{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:05:05Z","timestamp":1793293505875,"version":"4.5.0"},"reference-count":72,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:00:00Z","timestamp":1731628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Periodontitis is a chronic inflammatory disease driven by the accumulation of bacterial plaque and the host\u2019s immune response, leading to the destruction of periodontal tissues. Nutrition, particularly the intake of micronutrients with anti-inflammatory and antioxidant properties, plays a crucial role in maintaining periodontal health. This review explores the impact of various micronutrients\u2014vitamins (A, B, C, D, E), minerals (calcium, iron, zinc, potassium, copper, manganese, selenium), and omega-3 fatty acids\u2014on periodontal disease prevention and management. Deficiencies in these nutrients can exacerbate periodontal tissue damage by impairing immune responses, promoting oxidative stress, and reducing bone and tissue regeneration capabilities. While certain populations may be more vulnerable to these deficiencies, such as those following Western diets or living in low- and middle-income countries, even in developed nations, suboptimal nutrient intake is associated with worse periodontal outcomes. Although some studies suggest that supplementation of specific micronutrients may benefit periodontal therapy, the evidence remains inconclusive, necessitating further randomized clinical trials. This review underscores the importance of considering nutritional guidance in periodontal treatment protocols and highlights the need for tailored recommendations based on recent findings.<\/jats:p>","DOI":"10.3390\/nu16223901","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T06:59:13Z","timestamp":1731653953000},"page":"3901","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["The Impact of Nutritional Components on Periodontal Health: A Literature Review"],"prefix":"10.3390","volume":"16","author":[{"given":"Yarden","family":"Berg","sequence":"first","affiliation":[{"name":"Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus (RHCC), Haifa P.O. Box 9602, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0429-2883","authenticated-orcid":false,"given":"Eran","family":"Gabay","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus (RHCC), Haifa P.O. Box 9602, Israel"},{"name":"Faculty of Medicine, Technion\u2014Israel Institute of Technology, Haifa 3101101, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0391-0574","authenticated-orcid":false,"given":"Darko","family":"Bo\u017ei\u0107","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dental Medicine, HR-10000 Zagreb, Croatia"},{"name":"Department of Periodontology, University Hospital Centre Zagreb, HR-10000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamil Awad","family":"Shibli","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 12245-000, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8736-9753","authenticated-orcid":false,"given":"Ofir","family":"Ginesin","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus (RHCC), Haifa P.O. Box 9602, Israel"},{"name":"Faculty of Medicine, Technion\u2014Israel Institute of Technology, Haifa 3101101, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thabet","family":"Asbi","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus (RHCC), Haifa P.O. Box 9602, Israel"},{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 12245-000, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Takakura","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 12245-000, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5500-7961","authenticated-orcid":false,"given":"Yaniv","family":"Mayer","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus (RHCC), Haifa P.O. Box 9602, Israel"},{"name":"Faculty of Medicine, Technion\u2014Israel Institute of Technology, Haifa 3101101, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S173","DOI":"10.1002\/JPER.17-0721","article-title":"Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"89","author":"Papapanou","year":"2018","journal-title":"J. Periodontol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1600-0757.2012.00450.x","article-title":"Periodontitis: A host-mediated disruption of microbial homeostasis. 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