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(2020). Global Nutrition Report: Action on Equity to End Malnutrition, Development Initiatives Poverty Ltd."},{"key":"ref_2","unstructured":"GBD 2019 Risk Factors Collaborators (2020). Global burden of 87 risk factors in 204 countries and territories, 1990\u20132019: A systematic analysis for the Global Burden of Disease Study 2019. Lancet, 396, 1223\u20131249."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Neufingerl, N., and Eilander, A. (2021). Nutrient Intake and Status in Adults Consuming Plant-Based Diets Compared to Meat-Eaters: A Systematic Review. Nutrients, 14.","DOI":"10.3390\/nu14010029"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Noce, A., Di Lauro, M., Di Daniele, F., Zaitseva, A.P., Marrone, G., Borboni, P., and Di Daniele, N. (2021). Natural Bioactive Compounds Useful in Clinical Management of Metabolic Syndrome. 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Immunol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"372","DOI":"10.5507\/bp.2016.044","article-title":"The long-term effects of probiotics in the therapy of ulcerative colitis: A clinical study","volume":"160","author":"Palumbo","year":"2016","journal-title":"Biomed. Pap."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Corsello, A., Pugliese, D., Gasbarrini, A., and Armuzzi, A. (2020). Diet and Nutrients in Gastrointestinal Chronic Diseases. Nutrients, 12.","DOI":"10.3390\/nu12092693"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Zhang, P. (2022). Influence of Foods and Nutrition on the Gut Microbiome and Implications for Intestinal Health. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23179588"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Rinninella, E., Cintoni, M., Raoul, P., Lopetuso, L.R., Scaldaferri, F., Pulcini, G., Miggiano, G.A.D., Gasbarrini, A., and Mele, M.C. (2019). 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Immunol., 11.","DOI":"10.3389\/fimmu.2020.594150"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Xu, G.B., Cai, M., Kadayifci, F.Z., Dong, J., Zheng, S., Mei, W., Zhao, W., Pan, Y.-X., and Chen, H. (2023). Increasing dietary nutrient levels modulates colon immune adaptation and alleviates inflammation in the epithelial heterogeneous nuclear ribonucleoprotein I (Hnrnp I) knockout mice. J. Nutr. 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