{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T22:42:38Z","timestamp":1785278558830,"version":"3.55.0"},"reference-count":58,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T00:00:00Z","timestamp":1733529600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"MHLW, Research on Emerging and Re-emerging Infectious Diseases and Immunization","award":["JPMH21HA2011"],"award-info":[{"award-number":["JPMH21HA2011"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: COVID-19 patients develop various clinical symptoms, including malnutrition. However, the risk factors for long-term nutritional disorders remain unclear. Identifying these factors is crucial for preventing nutritional disorders by initiating early nutritional interventions. Methods: This was a post hoc analysis of COVID-19 Recovery Study II (CORESII). The study included adult patients hospitalized for COVID-19 and discharged from the hospital. Information, including post-COVID-19 symptoms one month after onset and changes in daily life during the first year, was collected using a self-administered questionnaire sent one year after hospital discharge. We examined the association between baseline characteristics, disease severity, and symptoms that persisted one month after onset with malnutrition disorders one year after onset, defined as a Malnutrition Universal Screening Tool score \u22651, using a logistic regression analysis. Results: A total of 1081 patients (mean age of 56.0 years; 34% females; 38% admitted to the intensive care unit) were analyzed. Of these patients, 266 patients (24.6%) had malnutrition one year after onset. In a multivariable logistic regression analysis using variables that were significant in a univariate logistic regression analysis, the following factors were independently associated with malnutrition: BMI &lt; 18.5 kg\/m2 (odds ratio [95% confidence interval (CI)], 48.9 [14.3\u2013168]), 18.5 \u2264 BMI \u2264 20 (10.5 [5.89\u201318.8]), 30 &lt; BMI (2.64 [1.84\u20133.75]), length of hospital stay (1.01 [1.00\u20131.02]), maintenance dialysis (3.19 [1.19\u20138.61]), and difficulty concentrating one month after onset (1.73 [1.07\u20132.79]). Conclusions: Being underweight or obese, prolonged hospitalization, maintenance dialysis, and difficulty concentrating one month after onset were associated with a risk of malnutrition one year post-illness. Patients with these factors may be at a high risk of long-term nutritional disorders.<\/jats:p>","DOI":"10.3390\/nu16234234","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T08:17:49Z","timestamp":1733732269000},"page":"4234","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Risk Factors for Long-Term Nutritional Disorders One Year After COVID-19: A Post Hoc Analysis of COVID-19 Recovery Study II"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-7395-6931","authenticated-orcid":false,"given":"Keiichiro","family":"Kawabata","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, Yokohama City University Hospital, Kanagawa 236-0004, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8481-0294","authenticated-orcid":false,"given":"Kensuke","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Yokohama City University Hospital, Kanagawa 236-0004, Japan"},{"name":"Department of Emergency and Critical Care Medicine, Hitachi General Hospital, Ibaraki 317-0077, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8003-534X","authenticated-orcid":false,"given":"Naoki","family":"Kanda","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Hitachi General Hospital, Ibaraki 317-0077, Japan"},{"name":"Division of General Internal Medicine, Jichi Medical University, Tochigi 329-0431, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8234-9032","authenticated-orcid":false,"given":"Muneaki","family":"Hemmi","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Yokohama City University Hospital, Kanagawa 236-0004, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Suganuma","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Yokohama City University Hospital, Kanagawa 236-0004, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Muto","sequence":"additional","affiliation":[{"name":"Institute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo 162-8655, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arisa","family":"Iba","sequence":"additional","affiliation":[{"name":"Institute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo 162-8655, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miyuki","family":"Hori","sequence":"additional","affiliation":[{"name":"Institute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo 162-8655, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6886-5156","authenticated-orcid":false,"given":"Mariko","family":"Hosozawa","sequence":"additional","affiliation":[{"name":"Institute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo 162-8655, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyasu","family":"Iso","sequence":"additional","affiliation":[{"name":"Institute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo 162-8655, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e2111417","DOI":"10.1001\/jamanetworkopen.2021.11417","article-title":"Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19: A Systematic Review","volume":"4","author":"Nasserie","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"ref_2","unstructured":"WHO (2024, October 05). Long COVID, Post COVID-19 Condition. Available online: https:\/\/www.who.int\/europe\/news-room\/fact-sheets\/item\/post-covid-19-condition."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/S2213-2600(22)00126-6","article-title":"Health outcomes in people 2 years after surviving hospitalisation with COVID-19: A longitudinal cohort study","volume":"10","author":"Huang","year":"2022","journal-title":"Lancet Respir. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1016\/j.clnu.2022.07.033","article-title":"COVID-19: Lessons on malnutrition, nutritional care and public health from the ESPEN-WHO Europe call for papers","volume":"41","author":"Barazzoni","year":"2022","journal-title":"Clin. Nutr."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.clnesp.2021.03.002","article-title":"Prevalence and outcomes of malnutrition among hospitalized COVID-19 patients: A systematic review and meta-analysis","volume":"43","author":"Abate","year":"2021","journal-title":"Clin. Nutr. ESPEN"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.clnesp.2020.09.018","article-title":"Prevalence and severity of malnutrition in hospitalized COVID-19 patients","volume":"40","author":"Bedock","year":"2020","journal-title":"Clin. Nutr. ESPEN"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.clnesp.2021.02.009","article-title":"The prevalence of malnutrition and analysis of related factors among adult patients with the Coronavirus Disease 2019 (COVID 19) in a tertiary government hospital: The MalnutriCoV study","volume":"42","author":"Larrazabal","year":"2021","journal-title":"Clin. Nutr. ESPEN"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1111\/j.1532-5415.2010.03016.x","article-title":"Frequency of malnutrition in older adults: A multinational perspective using the mini nutritional assessment","volume":"58","author":"Kaiser","year":"2010","journal-title":"J. Am. Geriatr. Soc."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1007\/s40520-023-02526-4","article-title":"Malnutrition in COVID-19 survivors: Prevalence and risk factors","volume":"35","author":"Tosato","year":"2023","journal-title":"Aging Clin. Exp. Res."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"G\u00e9rard, M., Mahmutovic, M., Malgras, A., Michot, N., Scheyer, N., Jaussaud, R., Nguyen-Thi, P.L., and Quilliot, D. (2021). Long-Term Evolution of Malnutrition and Loss of Muscle Strength after COVID-19: A Major and Neglected Component of Long COVID-19. Nutrients, 13.","DOI":"10.3390\/nu13113964"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/agm2.12287","article-title":"Navigating sarcopenia in COVID-19 patients and survivors: Understanding the long-term consequences, transitioning from hospital to community with mechanisms and interventions for future preparedness","volume":"7","author":"Vaezi","year":"2024","journal-title":"Aging Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/j.clnu.2020.03.022","article-title":"ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection","volume":"39","author":"Barazzoni","year":"2020","journal-title":"Clin. Nutr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1016\/j.clnu.2021.05.006","article-title":"Nutritional management of individuals with obesity and COVID-19: ESPEN expert statements and practical guidance","volume":"41","author":"Barazzoni","year":"2022","journal-title":"Clin. Nutr."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/0194599820926473","article-title":"The Prevalence of Olfactory and Gustatory Dysfunction in COVID-19 Patients: A Systematic Review and Meta-analysis","volume":"163","author":"Tong","year":"2020","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1056\/NEJMoa2002032","article-title":"Clinical Characteristics of Coronavirus Disease 2019 in China","volume":"382","author":"Guan","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1016\/j.jamda.2021.07.003","article-title":"Prevalence and Predictors of Persistence of COVID-19 Symptoms in Older Adults: A Single-Center Study","volume":"22","author":"Tosato","year":"2021","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Kurtz, A., Grant, K., Marano, R., Arrieta, A., Grant, K., Feaster, W., Steele, C., and Ehwerhemuepha, L. (2021). Long-term effects of malnutrition on severity of COVID-19. Sci. Rep., 11.","DOI":"10.1038\/s41598-021-94138-z"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.clnesp.2023.04.001","article-title":"Predictive value of multiple variable models including nutritional risk score (NRS 2002) on mortality and length of stay of patients with covid-19 infections. The INCOVO study","volume":"55","author":"Fatemeh","year":"2023","journal-title":"Clin. Nutr. ESPEN"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1186\/s13054-020-03286-7","article-title":"Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19","volume":"24","author":"Whittle","year":"2020","journal-title":"Crit. Care"},{"key":"ref_20","first-page":"8291","article-title":"Post-COVID-19 syndrome in a cohort of hospitalized COVID-19 patients","volume":"27","author":"Bildirici","year":"2023","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J. Biomed. Inform."},{"key":"ref_22","unstructured":"(2024, October 05). The International Severe Acute Respiratory and Emerging Infection Consortium Follow-Up Form. Available online: https:\/\/isaric.org\/research\/covid-19-clinical-research-resources\/covid-19-long-term-follow-up-study-old\/."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Zhou, T., Guan, H., Wang, L., Zhang, Y., Rui, M., and Ma, A. (2021). Health-Related Quality of Life in Patients With Different Diseases Measured With the EQ-5D-5L: A Systematic Review. Front. Public Health, 9.","DOI":"10.3389\/fpubh.2021.675523"},{"key":"ref_24","first-page":"47","article-title":"Developing a Japanese version of the EQ-5D-5L value set","volume":"64","author":"Ikeda","year":"2015","journal-title":"J. Natl. Inst. Public Health"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Fern\u00e1ndez-de-Las-Pe\u00f1as, C., Rodr\u00edguez-Jim\u00e9nez, J., Palacios-Ce\u00f1a, M., de-la-Llave-Rinc\u00f3n, A.I., Fuensalida-Novo, S., Florencio, L.L., Ambite-Quesada, S., Ortega-Santiago, R., Arias-Bur\u00eda, J.L., and Liew, B.X.W. (2022). Psychometric Properties of the Hospital Anxiety and Depression Scale (HADS) in Previously Hospitalized COVID-19 Patients. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19159273"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Olss\u00f8n, I., Mykletun, A., and Dahl, A.A. (2005). The Hospital Anxiety and Depression Rating Scale: A cross-sectional study of psychometrics and case finding abilities in general practice. BMC Psychiatry, 5.","DOI":"10.1186\/1471-244X-5-46"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1378\/chest.93.3.580","article-title":"Evaluation of clinical methods for rating dyspnea","volume":"93","author":"Mahler","year":"1988","journal-title":"Chest"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"106984","DOI":"10.1016\/j.rmed.2022.106984","article-title":"Qualitative validation of the modified Medical Research Council (mMRC) dyspnoea scale as a patient-reported measure of breathlessness severity","volume":"203","author":"Sunjaya","year":"2022","journal-title":"Respir. Med."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/bjc.1993.140","article-title":"Performance status assessment in cancer patients. An inter-observer variability study","volume":"67","author":"Klee","year":"1993","journal-title":"Br. J. Cancer"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.6004\/jnccn.2024.0001","article-title":"Revisiting the Association of ECOG Performance Status With Clinical Outcomes in Diverse Patients With Cancer","volume":"22","author":"Kumar","year":"2024","journal-title":"J. Natl. Compr. Canc. Netw."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1079\/BJN20041258","article-title":"Malnutrition in hospital outpatients and inpatients: Prevalence, concurrent validity and ease of use of the \u2018malnutrition universal screening tool\u2019 (\u2018MUST\u2019) for adults","volume":"92","author":"Stratton","year":"2004","journal-title":"Br. J. Nutr."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1001\/jamaneurol.2020.1127","article-title":"Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China","volume":"77","author":"Mao","year":"2020","journal-title":"JAMA Neurol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"104364","DOI":"10.1016\/j.jcv.2020.104364","article-title":"Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan, China","volume":"127","author":"Zhang","year":"2020","journal-title":"J. Clin. Virol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2777","DOI":"10.1007\/s00415-020-09974-2","article-title":"Clinical manifestations and evidence of neurological involvement in 2019 novel coronavirus SARS-CoV-2: A systematic review and meta-analysis","volume":"267","author":"Wang","year":"2020","journal-title":"J. Neurol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1056\/NEJMoa2015432","article-title":"Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19","volume":"383","author":"Ackermann","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1056\/NEJMc2019373","article-title":"Neuropathological Features of Covid-19","volume":"383","author":"Solomon","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/s41579-023-00878-2","article-title":"The evolution of SARS-CoV-2","volume":"21","author":"Markov","year":"2023","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_38","first-page":"37","article-title":"SARS-CoV-2 infection and multi-organ system damage: A review","volume":"23","author":"Rabaan","year":"2023","journal-title":"Biomol. Biomed."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.1007\/s00415-020-09966-2","article-title":"Multifocal laminar cortical brain lesions: A consistent MRI finding in neuro-COVID-19 patients","volume":"267","author":"Anzalone","year":"2020","journal-title":"J. Neurol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"100484","DOI":"10.1016\/j.eclinm.2020.100484","article-title":"Cerebral Micro-Structural Changes in COVID-19 Patients\u2014An MRI-based 3-month Follow-up Study","volume":"25","author":"Lu","year":"2020","journal-title":"EClinicalMedicine"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1056\/NEJMoa2311330","article-title":"Cognition and Memory after Covid-19 in a Large Community Sample","volume":"390","author":"Hampshire","year":"2024","journal-title":"N. Engl. J. Med."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/pcn.13160","article-title":"COVID-19 pandemic-onset anorexia nervosa: Three adolescent cases","volume":"74","year":"2020","journal-title":"Psychiatry Clin. Neurosci."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Gibson, D., and Mehler, P.S. (2019). Anorexia Nervosa and the Immune System-A Narrative Review. J. Clin. Med., 8.","DOI":"10.3390\/jcm8111915"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1159\/000484679","article-title":"Mechanistic Links Underlying the Impact of C-Reactive Protein on Muscle Mass in Elderly","volume":"44","author":"Wilkinson","year":"2017","journal-title":"Cell Physiol. Biochem."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Ai, J.W., Zi, H., Wang, Y., Huang, Q., Wang, N., Li, L.Y., Pei, B., Ji, J., and Zeng, X.T. (2020). Clinical Characteristics of COVID-19 Patients With Gastrointestinal Symptoms: An Analysis of Seven Patients in China. Front. Med., 7.","DOI":"10.3389\/fmed.2020.00308"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"e00127-20","DOI":"10.1128\/JVI.00127-20","article-title":"Receptor Recognition by the Novel Coronavirus from Wuhan: An Analysis Based on Decade-Long Structural Studies of SARS Coronavirus","volume":"94","author":"Wan","year":"2020","journal-title":"J. Virol."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Hawkings, M.J., Vaselli, N.M., Charalampopoulos, D., Brierley, L., Elliot, A.J., Buchan, I., and Hungerford, D. (2023). A Systematic Review of the Prevalence of Persistent Gastrointestinal Symptoms and Incidence of New Gastrointestinal Illness after Acute SARS-CoV-2 Infection. Viruses, 15.","DOI":"10.1101\/2023.04.26.23289142"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1093\/ndt\/gfac008","article-title":"Recovery of dialysis patients with COVID-19: Health outcomes 3 months after diagnosis in ERACODA","volume":"37","author":"Hemmelder","year":"2022","journal-title":"Nephrol. Dial. Transplant."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Sousa-Catita, D., Godinho, C., Mascarenhas, P., Quaresma, F., and Fonseca, J. (2022). The Effects of an Intensive Rehabilitation Program on the Nutritional and Functional Status of Post-COVID-19 Pneumonia Patients. Nutrients, 14.","DOI":"10.3390\/nu14122501"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1016\/j.clnu.2020.10.043","article-title":"COVID-19 is associated with clinically significant weight loss and risk of malnutrition, independent of hospitalisation: A post-hoc analysis of a prospective cohort study","volume":"40","author":"Sofia","year":"2021","journal-title":"Clin. Nutr."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.clnu.2020.08.021","article-title":"Malnutrition and nutritional therapy in patients with SARS-CoV-2 disease","volume":"40","author":"Pironi","year":"2021","journal-title":"Clin. Nutr."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Levy, D., Giannini, M., Oulehri, W., Riou, M., Marcot, C., Pizzimenti, M., Debrut, L., Charloux, A., Geny, B., and Meyer, A. (2022). Long Term Follow-Up of Sarcopenia and Malnutrition after Hospitalization for COVID-19 in Conventional or Intensive Care Units. Nutrients, 14.","DOI":"10.3390\/nu14040912"},{"key":"ref_53","first-page":"53","article-title":"Long-term outcomes from critical care","volume":"39","author":"Morgan","year":"2021","journal-title":"Surgery"},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Hatakeyama, J., Inoue, S., Liu, K., Yamakawa, K., Nishida, T., Ohshimo, S., Hashimoto, S., Kanda, N., Maruyama, S., and Ogata, Y. (2022). Prevalence and Risk Factor Analysis of Post-Intensive Care Syndrome in Patients with COVID-19 Requiring Mechanical Ventilation: A Multicenter Prospective Observational Study. J. Clin. Med., 11.","DOI":"10.3390\/jcm11195758"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1007\/s40620-022-01295-z","article-title":"Long-lasting clinical symptoms 6 months after COVID-19 infection in the French national cohort of patients on dialysis","volume":"35","author":"Belkacemi","year":"2022","journal-title":"J. Nephrol."},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Sahathevan, S., Khor, B.H., Ng, H.M., Gafor, A.H.A., Mat Daud, Z.A., Mafra, D., and Karupaiah, T. (2020). Understanding Development of Malnutrition in Hemodialysis Patients: A Narrative Review. Nutrients, 12.","DOI":"10.3390\/nu12103147"},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Gualtieri, P., Falcone, C., Romano, L., Macheda, S., Correale, P., Arciello, P., Polimeni, N., and Lorenzo, A. (2020). Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21134670"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.nut.2010.07.004","article-title":"Diverse roles of leptin in the gastrointestinal tract: Modulation of motility, absorption, growth, and inflammation","volume":"27","author":"Yarandi","year":"2011","journal-title":"Nutrition"}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/16\/23\/4234\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:49:36Z","timestamp":1760114976000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/16\/23\/4234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,7]]},"references-count":58,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["nu16234234"],"URL":"https:\/\/doi.org\/10.3390\/nu16234234","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,7]]}}}