{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T23:54:06Z","timestamp":1783727646250,"version":"3.55.0"},"reference-count":62,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T00:00:00Z","timestamp":1734998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department of Health of the Generalitat de Catalunya, Strategic Plan for Research and Innovation in Health (PERIS, 2022)","award":["SLT021\/21\/000009"],"award-info":[{"award-number":["SLT021\/21\/000009"]}]},{"name":"Department of Health of the Generalitat de Catalunya, Strategic Plan for Research and Innovation in Health (PERIS, 2022)","award":["4R21\/029"],"award-info":[{"award-number":["4R21\/029"]}]},{"name":"Department of Health of the Generalitat de Catalunya, Strategic Plan for Research and Innovation in Health (PERIS, 2022)","award":["2023 DI 00070"],"award-info":[{"award-number":["2023 DI 00070"]}]},{"name":"Research project","award":["SLT021\/21\/000009"],"award-info":[{"award-number":["SLT021\/21\/000009"]}]},{"name":"Research project","award":["4R21\/029"],"award-info":[{"award-number":["4R21\/029"]}]},{"name":"Research project","award":["2023 DI 00070"],"award-info":[{"award-number":["2023 DI 00070"]}]},{"name":"IDIAP 2020 project","award":["SLT021\/21\/000009"],"award-info":[{"award-number":["SLT021\/21\/000009"]}]},{"name":"IDIAP 2020 project","award":["4R21\/029"],"award-info":[{"award-number":["4R21\/029"]}]},{"name":"IDIAP 2020 project","award":["2023 DI 00070"],"award-info":[{"award-number":["2023 DI 00070"]}]},{"name":"AGAUR Doctorats Industrials","award":["SLT021\/21\/000009"],"award-info":[{"award-number":["SLT021\/21\/000009"]}]},{"name":"AGAUR Doctorats Industrials","award":["4R21\/029"],"award-info":[{"award-number":["4R21\/029"]}]},{"name":"AGAUR Doctorats Industrials","award":["2023 DI 00070"],"award-info":[{"award-number":["2023 DI 00070"]}]},{"name":"L. Cabricano-Canga of Generalitat de Catalunya","award":["SLT021\/21\/000009"],"award-info":[{"award-number":["SLT021\/21\/000009"]}]},{"name":"L. Cabricano-Canga of Generalitat de Catalunya","award":["4R21\/029"],"award-info":[{"award-number":["4R21\/029"]}]},{"name":"L. Cabricano-Canga of Generalitat de Catalunya","award":["2023 DI 00070"],"award-info":[{"award-number":["2023 DI 00070"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Multidisciplinary lifestyle interventions are being researched to treat fibromyalgia. However, the impact of nutrition as a key treatment component is little studied. This study aimed to evaluate the effectiveness of the SYNCHRONIZE + lifestyle multidisciplinary intervention in improving adherence to the Mediterranean diet, nutrition quality and dietary intake pattern in persons with fibromyalgia and chronic fatigue syndrome. Methods: A pragmatic randomized clinical trial was conducted in primary care. Data were collected using the 17-item energy-restricted Mediterranean Adherence Screener (er-MEDAS), the food frequency questionnaire (sFFQ) and the 24 h recall questionnaire (24 HR), in addition to chrono-nutritional, anthropometric, and body composition data, at baseline and 3-, 6-, and 12- month follow-up visits, and statistically analyzed. Results: A total of 158 participants were evaluated. Results showed the effectiveness of the intervention in improving adherence to the Mediterranean diet. The adherence depended on the group-time interaction being positive and significant at 3 and 6 months post-intervention in the INT group and on the participant age and educational level. Specifically, the intake of legumes, fruits, vegetables, nuts and blue fish was increased, while the intake of sweets and pastries, butter and cream and red and processed meat was reduced. Furthermore, the intake of chips and candies was also reduced, and the consumption of fermented food (yogurts, cheese, kefir) increased. Thus, general diet quality improved. Interestingly, the intake of key nutrients such as protein and iron increased. Furthermore, the number of night eaters was decreased significantly. Muscle mass index was also improved in the intervention group. These results were maintained in the medium to long term. Conclusion: SYNCHRONIZE + is a brief, low-cost, multidisciplinary intervention effective in improving adherence to the Mediterranean diet and improving nutritional and dietary intake patterns in persons with fibromyalgia and chronic fatigue syndrome. Further evaluation of the effect on quality of life and symptoms is needed.<\/jats:p>","DOI":"10.3390\/nu17010011","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T09:00:57Z","timestamp":1735030857000},"page":"11","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effectiveness of the SYNCHRONIZE + Brief Intervention in Improving Mediterranean Diet Adherence, Nutritional Quality and Intake Pattern in Persons with Fibromyalgia and Chronic Fatigue Syndrome"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5876-7082","authenticated-orcid":false,"given":"No\u00e8lia","family":"Carrasco-Querol","sequence":"first","affiliation":[{"name":"Unitat de Suport a la Recerca Terres de l\u2019Ebre, Fundaci\u00f3 Institut Universitari per a la Recerca a l\u2019Atenci\u00f3 Prim\u00e0ria de Salut Jordi Gol I Gurina (IDIAPJGol), 43500 Tortosa, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0094-4042","authenticated-orcid":false,"given":"Lorena","family":"Cabricano-Canga","sequence":"additional","affiliation":[{"name":"EAP Dreta Eixample, CAP Roger de Flor, C\/Roger de Flor 194, 08013 Barcelona, Spain"},{"name":"Departament de Bioqu\u00edmica i Biotecnologia, Facultat de Medicina i Ci\u00e8ncies de la Salut, Universitat Rovira i Virgili (URV), 43201 Reus, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2065-2981","authenticated-orcid":false,"given":"Nerea","family":"Bueno Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Unitat de Suport a la Recerca Terres de l\u2019Ebre, Fundaci\u00f3 Institut Universitari per a la Recerca a l\u2019Atenci\u00f3 Prim\u00e0ria de Salut Jordi Gol I Gurina (IDIAPJGol), 43500 Tortosa, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carme","family":"Mart\u00edn-Borr\u00e0s","sequence":"additional","affiliation":[{"name":"Unitat de Suport a la Recerca Terres de l\u2019Ebre, Fundaci\u00f3 Institut Universitari per a la Recerca a l\u2019Atenci\u00f3 Prim\u00e0ria de Salut Jordi Gol I Gurina (IDIAPJGol), 43500 Tortosa, Spain"},{"name":"Servei d\u2019Atenci\u00f3 Prim\u00e0ria Terres de l\u2019Ebre, Institut Catal\u00e0 de la Salut (ICS), 43500 Tortosa, Spain"},{"name":"Departament d\u2019Activitat F\u00edsica i Fisioter\u00e0pia, EUSES Terres de l\u2019Ebre, Universitat Rovira i Virgili (URV), 43500 Tortosa, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3272-6861","authenticated-orcid":false,"given":"Alessandra Queiroga","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Unitat de Suport a la Recerca Terres de l\u2019Ebre, Fundaci\u00f3 Institut Universitari per a la 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