{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:17:53Z","timestamp":1790979473603,"version":"4.1.0"},"reference-count":41,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,12]],"date-time":"2025-01-12T00:00:00Z","timestamp":1736640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Special Program for Science &amp; Technology Basic Resources Investigation of China","award":["2017FY101100"],"award-info":[{"award-number":["2017FY101100"]}]},{"name":"National Special Program for Science &amp; Technology Basic Resources Investigation of China","award":["2017FY101107"],"award-info":[{"award-number":["2017FY101107"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: The prevalence of both myopia and obesity is increasing among children and adolescents around the world. We aimed to examine the association between weight status and myopia in Chinese children and adolescents. Methods: The analysis included 35,108 participants aged 6\u201317 from a nationwide cross-sectional survey. Results: Our results indicated that girls with overweight and obesity had higher odds ratio (OR) of myopia and mild myopia: ages 6\u20138 (OR = 1.33, 95% CI: 1.01\u20131.76; OR = 1.71, 95% CI: 1.14\u20132.55) and 9\u201311 (OR = 1.22, 95% CI: 1.03\u20131.44; OR = 1.31, 95% CI: 1.06\u20131.62). Myopic boys had higher body fat percentages (BFP) at ages 6\u20138 (\u03b2 = 1.18, 95% CI: 0.38\u20131.98), 9\u201311 (\u03b2 = 0.58, 95% CI: 0.08\u20131.07), and 15\u201317 (\u03b2 = 0.42, 95% CI: 0.03\u20130.80), and higher body mass index (BMI) at ages 9\u201311 (\u03b2 = 0.30, 95% CI: 0.12\u20130.48) and 12\u201314 (\u03b2 = 0.19, 95% CI: 0.02\u20130.38). Girls had higher BFP at ages 9\u201311 (\u03b2 = 0.62, 95% CI: 0.19\u20131.05) and 12\u201314 (\u03b2 =0.53, 95% CI: 0.19\u20130.88) and higher BMI at 9\u201311 (\u03b2 = 0.53, 95% CI: 0.34\u20130.73). Furthermore, the dose\u2013response curves revealed a significant gender- and age-specific association between BMI, BFP, and myopia odds ratio. Conclusions: the study found an association between overweight or obesity and myopia in girls aged 6\u201311, and indicated that high BFP and BMI are associated with myopia, varying by sex and age.<\/jats:p>","DOI":"10.3390\/nu17020260","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T05:40:40Z","timestamp":1736746840000},"page":"260","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Weight Status and Myopia in Children and Adolescents: A Nationwide Cross-Sectional Study of China"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4315-9271","authenticated-orcid":false,"given":"Chunjie","family":"Yin","sequence":"first","affiliation":[{"name":"School of Public Health, Xinjiang Medical University, Urumqi 830017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3259-3969","authenticated-orcid":false,"given":"Qian","family":"Gan","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People\u2019s Republic of China, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peipei","family":"Xu","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People\u2019s Republic of China, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Titi","family":"Yang","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People\u2019s Republic of China, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Xu","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People\u2019s Republic of China, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Cao","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People\u2019s Republic of China, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongliang","family":"Wang","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People\u2019s Republic of China, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Pan","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People\u2019s Republic of China, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruihe","family":"Luo","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People\u2019s Republic of China, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Xiao","sequence":"additional","affiliation":[{"name":"School of Public Health, Xinjiang Medical University, Urumqi 830017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Public Health, Xinjiang Medical University, Urumqi 830017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People\u2019s Republic of China, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","article-title":"Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050","volume":"123","author":"Holden","year":"2016","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1038\/s41574-019-0176-8","article-title":"Obesity: Global epidemiology and pathogenesis","volume":"15","year":"2019","journal-title":"Nat. Rev. Endocrinol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e14562","DOI":"10.1111\/sms.14562","article-title":"Associations of school physical activity environment with comorbid obesity and myopia in children and adolescents: Findings from a Chinese national follow-up study","volume":"34","author":"Dang","year":"2024","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.ophtha.2018.10.029","article-title":"Potential Lost Productivity Resulting from the Global Burden of Myopia: Systematic Review, Meta-analysis, and Modeling","volume":"126","author":"Naidoo","year":"2019","journal-title":"Ophthalmology"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Ling, J., Chen, S., Zahry, N.R., and Kao, T.A. (2022). Economic burden of childhood overweight and obesity: A systematic review and meta-analysis. Obes. Rev., 24.","DOI":"10.1111\/obr.13535"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1002\/oby.23482","article-title":"Myopia and BMI: A nationwide study of 1.3 million adolescents","volume":"30","author":"Peled","year":"2022","journal-title":"Obesity"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1136\/bjophthalmol-2017-310292","article-title":"Environmental factors explain socioeconomic prevalence differences in myopia in 6-year-old children","volume":"102","author":"Tideman","year":"2018","journal-title":"Br. J. Ophthalmol."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Lee, S., Lee, H.-J., Lee, K.G., and Kim, J. (2022). Obesity and high myopia in children and adolescents: Korea National Health and Nutrition Examination Survey. PLoS ONE, 17.","DOI":"10.1371\/journal.pone.0265317"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"5579","DOI":"10.1167\/iovs.12-10106","article-title":"Prevalence of myopia and its association with body stature and educational level in 19-year-old male conscripts in Seoul, South Korea","volume":"53","author":"Jung","year":"2012","journal-title":"Investig. Opthalmol. Vis. Sci."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/112067219500500101","article-title":"Myopia and stature: Findings in a population of 106,926 males","volume":"5","author":"Rosner","year":"1995","journal-title":"Eur. J. Ophthalmol."},{"key":"ref_11","first-page":"703","article-title":"National Nutrition and Health Systematic Survey for 0\u201318 years old children in China: Study protocol for 6\u201318 years old children","volume":"51","author":"Zhang","year":"2022","journal-title":"J. Hyg. Res."},{"key":"ref_12","unstructured":"(2014). Screening Standard for Malnutrition of School-Age Children and Adolescents (Standard No. WS\/T456-2014)."},{"key":"ref_13","unstructured":"(2018). Screening for Overweight and Obesity Among School-Aged Children and Adolescents (Standard No. WS\/T 586-2018)."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.clnesp.2023.08.002","article-title":"Prediction of body fat percentage: Development and validation of new anthropometric equations","volume":"57","author":"Bennouar","year":"2023","journal-title":"Clin. Nutr. ESPEN"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s00394-008-0742-7","article-title":"Body composition obtained from the body mass index: An Italian study","volume":"47","author":"Martarelli","year":"2008","journal-title":"Eur. J. Nutr."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1080\/03630242.2011.623222","article-title":"Analysis of body composition methods in a community sample of African American women","volume":"51","author":"Lopez","year":"2011","journal-title":"Women Health"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.ophtha.2019.12.001","article-title":"Myopia and Childhood Migration: A Study of 607\u2009862 Adolescents","volume":"127","author":"Peled","year":"2020","journal-title":"Ophthalmology"},{"key":"ref_18","unstructured":"CAME OCo (2018). Application standard for detection and prevention of myopia in children and adolescents. Chin. J. Ophthalmol. Med., 8, 276\u2013288."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Lee, S.S.-Y., and Mackey, D.A. (2022). Prevalence and Risk Factors of Myopia in Young Adults: Review of Findings From the Raine Study. Front. Public Health, 10.","DOI":"10.3389\/fpubh.2022.861044"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1167\/iovs.63.1.8","article-title":"Annual Incidences and Progressions of Myopia and High Myopia in Chinese Schoolchildren Based on a 5-Year Cohort Study","volume":"63","author":"Li","year":"2022","journal-title":"Investig. Opthalmol. Vis. Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"386","DOI":"10.2188\/jea.JE20140258","article-title":"Five-Year Progression of Refractive Errors and Incidence of Myopia in School-Aged Children in Western China","volume":"26","author":"Zhou","year":"2016","journal-title":"J. Epidemiol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1167\/iovs.04-0565","article-title":"Incidence and progression of myopia in Singaporean school children","volume":"46","author":"Saw","year":"2005","journal-title":"Investig. Opthalmol. Vis. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"7961","DOI":"10.1167\/iovs.12-10402","article-title":"The relationship between growth spurts and myopia in Singapore children","volume":"53","author":"Yip","year":"2012","journal-title":"Investig. Opthalmol. Vis. Sci."},{"key":"ref_24","first-page":"1803","article-title":"Risk factors associated with myopia in schoolchildren in Ireland","volume":"103","author":"Harrington","year":"2019","journal-title":"Br. J. Ophthalmol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12886-024-03282-3","article-title":"Association Between Weight-Adjusted Waist Index and Myopia in Adolescents and Young Adults: Results from Nhanes 1999\u20132008","volume":"24","author":"Shi","year":"2024","journal-title":"BMC Ophthalmol."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Zhu, Y., Wang, Z., Maruyama, H., Onoda, K., and Huang, Q. (2022). Body Fat Percentage and Normal-Weight Obesity in the Chinese Population: Development of a Simple Evaluation Indicator Using Anthropometric Measurements. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19074238"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12886-020-1316-6","article-title":"Factors associated with myopia in Korean children: Korea National Health and Nutrition Examination Survey 2016\u20132017 (KNHANES VII)","volume":"20","author":"Kim","year":"2020","journal-title":"BMC Ophthalmol."},{"key":"ref_28","first-page":"1","article-title":"An epidemiological study of the risk factors associated with myopia in young adult men in Korea","volume":"8","author":"Lee","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.ophtha.2010.09.025","article-title":"Myopia over the lifecourse: Prevalence and early life influences in the 1958 British birth cohort","volume":"118","author":"Rahi","year":"2010","journal-title":"Ophthalmology"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.2147\/JMDH.S458978","article-title":"Inverse L-Shaped Association Between Body Mass Index and Myopia in Chinese Schoolchildren: A Pilot Study","volume":"17","author":"Zheng","year":"2024","journal-title":"J. Multidiscip. Healthc."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1034\/j.1600-0420.2002.800203.x","article-title":"An evolutionary analysis of the aetiology and pathogenesis of juvenile-onset myopia","volume":"80","author":"Cordain","year":"2002","journal-title":"Acta Ophthalmol. Scand."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0021-5155(99)00098-2","article-title":"Changes in refraction caused by induction of acute hyperglycemia in healthy volunteers","volume":"43","author":"Furushima","year":"1999","journal-title":"Jpn. J. Ophthalmol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.pmedr.2017.08.003","article-title":"Attainment of \u20185-2-1-0\u2019 obesity recommendations in preschool-aged children","volume":"8","author":"Khalsa","year":"2017","journal-title":"Prev. Med. Rep."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1001\/jama.2015.10803","article-title":"Effect of Time Spent Outdoors at School on the Development of Myopia Among Children in China: A Randomized Clinical Trial","volume":"314","author":"He","year":"2015","journal-title":"JAMA"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Yin, C., Gan, Q., Xu, P., Yang, T., Xu, J., Cao, W., Wang, H., Pan, H., Ren, Z., and Xiao, H. (2023). Dietary Patterns and Associations with Myopia in Chinese Children. Nutrients, 15.","DOI":"10.3390\/nu15081946"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Matsumura, S., Dannoue, K., Kawakami, M., Uemura, K., Kameyama, A., Takei, A., and Hori, Y. (2022). Prevalence of Myopia and Its Associated Factors Among Japanese Preschool Children. Front. Public Health, 10.","DOI":"10.3389\/fpubh.2022.901480"},{"key":"ref_37","first-page":"713","article-title":"Relationship between sugary food intake and myopia in 11\u201314 years old Chinese children in 2019\u20132021","volume":"51","author":"Ren","year":"2022","journal-title":"J. Hyg. Res."},{"key":"ref_38","first-page":"707","article-title":"Association of beverages intake with myopia among 11\u201314-year-old Chinese children in 2019\u20132021","volume":"51","author":"Xu","year":"2022","journal-title":"J. Hyg. Res."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1001\/jamaophthalmol.2014.4899","article-title":"Secular trends of reduced visual acuity from 1985 to 2010 and disease burden projection for 2020 and 2030 among primary and secondary school students in China","volume":"133","author":"Sun","year":"2015","journal-title":"JAMA Ophthalmol."},{"key":"ref_40","first-page":"1281","article-title":"Establishment and exploration of the mechanism of Co-morbidity, Shared Etiology, and Shared Prevention of major health problems of children and adolescents","volume":"44","author":"Song","year":"2023","journal-title":"Chin. J. Sch. Health"},{"key":"ref_41","first-page":"1333","article-title":"Progress on the relationship between high-sugar diet and myopia development","volume":"23","author":"Wang","year":"2023","journal-title":"Int. Eye Sci."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/17\/2\/260\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:27:10Z","timestamp":1759919230000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/17\/2\/260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,12]]},"references-count":41,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,1]]}},"alternative-id":["nu17020260"],"URL":"https:\/\/doi.org\/10.3390\/nu17020260","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,12]]}}}