{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:09:49Z","timestamp":1792084189199,"version":"4.4.0"},"reference-count":32,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fetal Medicine Foundation","award":["1037116"],"award-info":[{"award-number":["1037116"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: To assess the incidence of dysglycaemia and metabolic syndrome and factors associated with them 5 months postpartum in women with gestational diabetes mellitus (GDM) in their last pregnancy. Methods: We conducted an observational prospective cohort study in 558 women with previous GDM who attended a 5-month postpartum follow-up clinic. Backward elimination was performed to select significant factors for the multivariable logistic regression model. Dysglycaemia (prediabetes and type 2 diabetes (T2D)) and metabolic syndrome were used as outcomes in separate models. Results: Dysglycaemia was diagnosed in 202 (36.2%) women, including 174 (31.2%) with prediabetes and 28 (5.0%) with T2D. Women with dysglycaemia, compared with those with normoglycaemia, were more likely to be of black ethnicity (33.2 vs. 20.5%) and have severe GDM (31.7 vs. 16%), a higher postpartum BMI (29.5 vs. 27.6 kg\/m2), and metabolic syndrome (20 vs. 7%). Multivariable logistic regression analysis showed that significant predictors of dysglycaemia were black (OR 2.09; 95% CI: 1.27\u20133.46) and mixed ethnicity (OR 3.05; 95% CI: 1.26\u20137.42), diagnosis of GDM before 24 weeks gestation (OR 3.05, 95% CI: 1.90\u20134.91), and treatment of GDM with metformin (OR 1.63; 95% CI: 1.05\u20132.55) or insulin (OR 2.08; 95% CI: 1.14\u20133.79) rather than diet alone. Significant predictors of metabolic syndrome were postpartum maternal BMI (OR 5.49; 95% CI: 2.60\u201311.59) and absence of breastfeeding (OR 2.14; 95% CI: 1.21\u20133.77). Conclusions: At 5 months postpartum, a high proportion of women who developed GDM showed evidence of dysglycaemia. Future studies should investigate interventions that could reduce the risk of short- and long-term consequences of suboptimal cardiometabolic health in such women.<\/jats:p>","DOI":"10.3390\/nu17030390","type":"journal-article","created":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T05:50:53Z","timestamp":1737525053000},"page":"390","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Predictors of Cardiometabolic Health a Few Months Postpartum in Women Who Had Developed Gestational Diabetes"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9359-997X","authenticated-orcid":false,"given":"Cristina","family":"G\u00f3mez Fern\u00e1ndez","sequence":"first","affiliation":[{"name":"Harris Birthright Research Centre for Fetal Medicine, King\u2019s College, London SE5 8BB, UK"},{"name":"Faculty of Medicine, Complutense University of Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0419-9582","authenticated-orcid":false,"given":"Rajna","family":"Golubic","sequence":"additional","affiliation":[{"name":"Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford OX3 9DU, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rea","family":"Mitsigiorgi","sequence":"additional","affiliation":[{"name":"Harris Birthright Research Centre for Fetal Medicine, King\u2019s College, London SE5 8BB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanvi","family":"Mansukhani","sequence":"additional","affiliation":[{"name":"Harris Birthright Research Centre for Fetal Medicine, King\u2019s College, London SE5 8BB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josip","family":"Car","sequence":"additional","affiliation":[{"name":"Department of Women and Children\u2019s Health, School of Life Course and Population Sciences, King\u2019s College London, London SE5 8BB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kypros H.","family":"Nicolaides","sequence":"additional","affiliation":[{"name":"Harris Birthright Research Centre for Fetal Medicine, King\u2019s College, London SE5 8BB, UK"},{"name":"Department of Women and Children\u2019s Health, School of Life Course and Population Sciences, King\u2019s College London, London SE5 8BB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"American Diabetes Association Professional Practice Committee (2022). 2. 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