{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T01:04:32Z","timestamp":1793581472869,"version":"4.5.0"},"reference-count":84,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T00:00:00Z","timestamp":1738022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Michael Smith Health Research BC Health Professional Investigator Award"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Emerging evidence underscores the pivotal role of diet in preventing and managing inflammatory bowel disease (IBD). As our comprehension of the microbiome\u2019s role in IBD expands, dietary modifications are increasingly recognized as potential adjuncts or primary therapeutic strategies. Key components of the Mediterranean diet (MD)\u2014including microbiota-accessible carbohydrates, omega-3 fatty acids, polyphenols, and antioxidants\u2014have demonstrated promise in enhancing gut microbiota diversity and reducing intestinal inflammation, making it a practical approach for managing IBD. Moreover, the MD offers additional benefits considering the rising prevalence of comorbid chronic inflammatory conditions such as diabetes, cardiovascular disease, and obesity in IBD patients. The purpose of this narrative review was to provide an overview of the feasibility and clinical outcomes of the MD and offer evidence-based guidance for researchers and practitioners on how to adapt the MD to patients with IBD. According to several cross-sectional and interventional studies, the MD is feasible for patients with IBD and confers several benefits, such as reduced inflammation, improved disease activity, and enhanced quality of life, with a strong adherence rate and minimal adverse effects. To facilitate knowledge translation, we provide a practical framework for integrating the MD as a nutritional therapy for IBD, including specific recommendations and messaging that researchers, practitioners, and patients can use. By synthesizing current evidence and offering actionable insights, the aim is to facilitate the integration of the MD into IBD management, with the potential to improve patient outcomes.<\/jats:p>","DOI":"10.3390\/nu17030470","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T07:54:08Z","timestamp":1738050848000},"page":"470","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["From Evidence to Practice: A Narrative Framework for Integrating the Mediterranean Diet into Inflammatory Bowel Disease Management"],"prefix":"10.3390","volume":"17","author":[{"given":"Riya Gautam","family":"Naik","sequence":"first","affiliation":[{"name":"Department of Biology, Irving K. Barber Faculty of Science, University of British Columbia Okanagan, Kelowna, BC V1V 1V7, Canada"},{"name":"Centre for Chronic Disease Prevention and Management, Southern Medical Program, Faculty of Medicine, University of British Columbia, Kelowna, BC V1V 1V7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah A.","family":"Purcell","sequence":"additional","affiliation":[{"name":"Centre for Chronic Disease Prevention and Management, Southern Medical Program, Faculty of Medicine, University of British Columbia, Kelowna, BC V1V 1V7, Canada"},{"name":"Division of Endocrinology, Department of Medicine, University of British Columbia, Vancouver, BC V5Z 1M9, Canada"},{"name":"School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC V1V 1V7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie L.","family":"Gold","sequence":"additional","affiliation":[{"name":"The Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Christiansen","sequence":"additional","affiliation":[{"name":"Gastroenterology Clinic, Red Deer Regional Hospital, Department of Nutrition Services, Alberta Health Services, Red Deer, AB T4N 4E7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leah D.","family":"D\u2019Aloisio","sequence":"additional","affiliation":[{"name":"Department of Biology, Irving K. Barber Faculty of Science, University of British Columbia Okanagan, Kelowna, BC V1V 1V7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9129-3632","authenticated-orcid":false,"given":"Maitreyi","family":"Raman","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7349-9445","authenticated-orcid":false,"given":"Natasha","family":"Haskey","sequence":"additional","affiliation":[{"name":"Department of Biology, Irving K. 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Hepatol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/ecco-jcc\/jjy004","article-title":"Primary non-response to tumor necrosis factor antagonists is associated with inferior response to second-line biologics in patients with Inflammatory bowel diseases: A systematic review and meta-analysis","volume":"12","author":"Singh","year":"2018","journal-title":"J. Crohns Colitis"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1016\/j.cgh.2020.01.028","article-title":"Changing Global Epidemiology of Inflammatory Bowel Diseases: Sustaining Health Care Delivery Into the 21st Century","volume":"18","author":"Ananthakrishnan","year":"2020","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/apt.16703","article-title":"Systematic review with meta-analysis: Environmental and dietary differences of inflammatory bowel disease in Eastern and Western populations","volume":"55","author":"Zhao","year":"2022","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1002\/ueg2.12319","article-title":"Environmental risk factors for inflammatory bowel disease","volume":"10","author":"Singh","year":"2022","journal-title":"United Eur. Gastroenterol. J."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Clemente-Su\u00e1rez, V.J., Beltr\u00e1n-Velasco, A.I., Redondo-Fl\u00f3rez, L., Mart\u00edn-Rodr\u00edguez, A., and Tornero-Aguilera, J.F. (2023). Global Impacts of Western Diet and Its Effects on Metabolism and Health: A Narrative Review. Nutrients, 15.","DOI":"10.3390\/nu15122749"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Garc\u00eda-Montero, C., Fraile-Mart\u00ednez, O., G\u00f3mez-Lahoz, A.M., Pekarek, L., Castellanos, A.J., Noguerales-Fraguas, F., Coca, S., Guijarro, L.G., Garc\u00eda-Honduvilla, N., and As\u00fansolo, A. (2021). Nutritional components in western diet versus mediterranean diet at the gut microbiota-immune system interplay. implications for health and disease. Nutrients, 13.","DOI":"10.3390\/nu13020699"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1053\/j.gastro.2023.11.303","article-title":"AGA Clinical Practice Update on Diet and Nutritional Therapies in Patients With Inflammatory Bowel Disease: Expert Review","volume":"166","author":"Hashash","year":"2024","journal-title":"Gastroenterology"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1017\/S1368980011002515","article-title":"Mediterranean diet pyramid today. Science and cultural updates","volume":"14","author":"Berry","year":"2011","journal-title":"Public Health Nutr."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1053\/j.gastro.2022.05.037","article-title":"Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation","volume":"163","author":"Turpin","year":"2022","journal-title":"Gastroenterology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1093\/ecco-jcc\/jjad073","article-title":"A Mediterranean Diet Pattern improves intestinal inflammation concomitant with reshaping of the bacteriome in ulcerative colitis: A randomized controlled trial","volume":"17","author":"Haskey","year":"2023","journal-title":"J. Crohns Colitis"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1053\/j.gastro.2021.05.047","article-title":"A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn\u2019s Disease","volume":"161","author":"Lewis","year":"2021","journal-title":"Gastroenterology"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Khavandegar, A., Heidarzadeh, A., Angoorani, P., Hasani-Ranjbar, S., Ejtahed, H.-S., Larijani, B., and Qorbani, M. (2024). Adherence to the Mediterranean diet can beneficially affect the gut microbiota composition: A systematic review. BMC Med. Genom., 17.","DOI":"10.1186\/s12920-024-01861-3"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1016\/j.cgh.2022.11.026","article-title":"Dietary Interventions for the Treatment of Inflammatory Bowel Diseases: An Updated Systematic Review and Meta-analysis","volume":"21","author":"Limketkai","year":"2023","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Reznikov, E.A., and Suskind, D.L. (2023). Current Nutritional Therapies in Inflammatory Bowel Disease: Improving Clinical Remission Rates and Sustainability of Long-Term Dietary Therapies. Nutrients, 15.","DOI":"10.3390\/nu15030668"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Aleksandrova, K., Romero-Mosquera, B., and Hernandez, V. (2017). Diet, gut microbiome and epigenetics: Emerging links with inflammatory bowel diseases and prospects for management and prevention. Nutrients, 9.","DOI":"10.20944\/preprints201707.0039.v1"},{"key":"ref_18","first-page":"CD012839","article-title":"Dietary interventions for induction and maintenance of remission in inflammatory bowel disease","volume":"2","author":"Limketkai","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1093\/ibd\/izz297","article-title":"Diet Therapy for Inflammatory Bowel Diseases: A Call to the Dining Table","volume":"26","author":"Limketkai","year":"2020","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Aldars-Garc\u00eda, L., Chaparro, M., and Gisbert, J.P. (2021). Systematic review: The gut microbiome and its potential clinical application in inflammatory bowel disease. Microorganisms, 9.","DOI":"10.3390\/microorganisms9050977"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2976","DOI":"10.4049\/jimmunol.1700105","article-title":"Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor\u2013Dependent Repression of Claudin-2","volume":"199","author":"Zheng","year":"2017","journal-title":"J. Immunol."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Zhao, M., Chu, J., Feng, S., Guo, C., Xue, B., He, K., and Li, L. (2023). Immunological mechanisms of inflammatory diseases caused by gut microbiota dysbiosis: A review. Biomed. Pharmacother., 164.","DOI":"10.1016\/j.biopha.2023.114985"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Linares, R., Franc\u00e9s, R., Guti\u00e9rrez, A., and Juanola, O. (2021). Bacterial Translocation as Inflammatory Driver in Crohn\u2019s Disease. Front. Cell Dev. Biol., 9.","DOI":"10.3389\/fcell.2021.703310"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1111\/all.15825","article-title":"Mechanisms of gut epithelial barrier impairment caused by food emulsifiers polysorbate 20 and polysorbate 80","volume":"78","author":"Ogulur","year":"2023","journal-title":"Allergy Eur. J. Allergy Clin. Immunol."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Wagenaar, C.A., van de Put, M., Bisschops, M., Walrabenstein, W., de Jonge, C.S., Herrema, H., and van Schaardenburg, D. (2021). The effect of dietary interventions on chronic inflammatory diseases in relation to the microbiome: A systematic review. Nutrients, 13.","DOI":"10.3390\/nu13093208"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Khademi, Z., Milajerdi, A., Larijani, B., and Esmaillzadeh, A. (2021). Dietary Intake of Total Carbohydrates, Sugar and Sugar-Sweetened Beverages, and Risk of Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies. Front. Nutr., 8.","DOI":"10.3389\/fnut.2021.707795"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1024\/0300-9831\/a000508","article-title":"A posteriori dietary patterns and risk of inflammatory bowel disease: A meta-analysis of observational studies","volume":"90","author":"Khorshidi","year":"2020","journal-title":"Int. J. Vitam. Nutr. Res."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1093\/ecco-jcc\/jjab219","article-title":"Western and Carnivorous Dietary Patterns are Associated with Greater Likelihood of IBD Development in a Large Prospective Population-based Cohort","volume":"16","author":"Peters","year":"2022","journal-title":"J. Crohns Colitis"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1093\/advances\/nmaa145","article-title":"Association of Dietary Fiber, Fruit, and Vegetable Consumption with Risk of Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis","volume":"12","author":"Milajerdi","year":"2021","journal-title":"Adv. Nutr."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/1751-2980.12910","article-title":"Systematic review and meta-analysis: Association of a pre-illness Western dietary pattern with the risk of developing inflammatory bowel disease","volume":"21","author":"Li","year":"2020","journal-title":"J. Dig. Dis."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1136\/gutjnl-2013-305304","article-title":"Long-term intake of dietary fat and risk of ulcerative colitis and Crohn\u2019s disease","volume":"63","author":"Ananthakrishnan","year":"2014","journal-title":"Gut"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00394-019-01901-0","article-title":"Dietary intake of fish, n-3 polyunsaturated fatty acids, and risk of inflammatory bowel disease: A systematic review and meta-analysis of observational studies","volume":"59","author":"Mozaffari","year":"2020","journal-title":"Eur. J. Nutr."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1136\/gutjnl-2020-322670","article-title":"Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome","volume":"70","author":"Bolte","year":"2021","journal-title":"Gut"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Deleu, S., Becherucci, G., Godny, L., Mentella, M.C., Petito, V., and Scaldaferri, F. (2024). The Key Nutrients in the Mediterranean Diet and Their Effects in Inflammatory Bowel Disease: A Narrative Review. Nutrients, 16.","DOI":"10.3390\/nu16234201"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Rodr\u00edguez-Daza, M.C., Pulido-Mateos, E.C., Lupien-Meilleur, J., Guyonnet, D., Desjardins, Y., and Roy, D. (2021). Polyphenol-Mediated Gut Microbiota Modulation: Toward Prebiotics and Further. Front. Nutr., 8.","DOI":"10.3389\/fnut.2021.689456"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"101605","DOI":"10.1016\/j.smim.2022.101605","article-title":"Specialized pro-resolving mediators as modulators of immune responses","volume":"59","author":"Julliard","year":"2022","journal-title":"Semin. Immunol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1093\/ecco-jcc\/jjad204","article-title":"The Impact of Dietary Interventions on the Microbiota in Inflammatory Bowel Disease: A Systematic Review","volume":"18","author":"Nieva","year":"2024","journal-title":"J. Crohns Colitis"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ibd\/izaa097","article-title":"Multidimensional Impact of Mediterranean Diet on IBD Patients","volume":"27","author":"Chicco","year":"2021","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Erol Do\u011fan, \u00d6., Karaca \u00c7elik, K.E., Ba\u015f, M., Alan, E.H., and \u00c7a\u011f\u0131n, Y.F. (2024). Effects of Mediterranean Diet, Curcumin, and Resveratrol on Mild-to-Moderate Active Ulcerative Colitis: A Multicenter Randomized Clinical Trial. Nutrients, 16.","DOI":"10.3390\/nu16101504"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Strauss, J.C., Haskey, N., Ramay, H.R., Ghosh, T.S., Taylor, L.M., Yousuf, M., Ohland, C., McCoy, K.D., Ingram, R.J.M., and Ghosh, S. (2023). Weighted Gene Co-Expression Network Analysis Identifies a Functional Guild and Metabolite Cluster Mediating the Relationship between Mucosal Inflammation and Adherence to the Mediterranean Diet in Ulcerative Colitis. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24087323"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1093\/ecco-jcc\/jjaa084","article-title":"A diversified dietary pattern is associated with a balanced gut microbial composition of faecalibacterium and escherichia\/Shigella in patients with crohn\u2019s disease in remission","volume":"14","author":"Zhang","year":"2020","journal-title":"J. Crohns Colitis"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1016\/j.cgh.2018.10.044","article-title":"Barriers and Facilitators to Mediterranean Diet Adoption by Patients With Nonalcoholic Fatty Liver Disease in Northern Europe","volume":"17","author":"Haigh","year":"2019","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/jhn.12523","article-title":"Barriers to adopting a Mediterranean diet in Northern European adults at high risk of developing cardiovascular disease","volume":"31","author":"Moore","year":"2018","journal-title":"J. Hum. Nutr. Diet."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1016\/j.cgh.2023.05.006","article-title":"Breaking Barriers in Dietary Research: Strategies to Diversify Recruitment in Clinical Studies and Develop Culturally Tailored Diets for Hispanic Communities Living With Inflammatory Bowel Disease","volume":"21","author":"Damas","year":"2023","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.3945\/ajcn.111.031484","article-title":"Nut intake and adiposity: Meta-analysis of clinical trials","volume":"97","author":"Basora","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"5516","DOI":"10.1039\/D3FO00488K","article-title":"Olive oil and body fat: A systematic review with meta-analysis","volume":"14","author":"Santos","year":"2023","journal-title":"Food Funct."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1007\/s00394-019-01972-z","article-title":"Adherence to Mediterranean diet in Crohn\u2019s disease","volume":"59","author":"Papada","year":"2020","journal-title":"Eur. J. Nutr."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1007\/s00394-019-02158-3","article-title":"Adherence to the Mediterranean diet is associated with decreased fecal calprotectin in patients with ulcerative colitis after pouch surgery","volume":"59","author":"Godny","year":"2020","journal-title":"Eur. J. Nutr."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Naqvi, S.A., Taylor, L.M., Panaccione, R., Ghosh, S., Barkema, H.W., Hotte, N., Shommu, N., Kaur, S., Reimer, R.A., and Madsen, K.L. (2021). Dietary patterns, food groups and nutrients in Crohn\u2019s disease: Associations with gut and systemic inflammation. Sci. Rep., 11.","DOI":"10.1038\/s41598-020-80924-8"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.clnesp.2021.09.726","article-title":"Adherence to mediterranean diet in patients with inflammatory bowel disease","volume":"46","author":"Fiorindi","year":"2021","journal-title":"Clin. Nutr. ESPEN"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"714","DOI":"10.5152\/tjg.2023.22193","article-title":"The Effect of Adherence to Mediterranean Diet on Disease Activity in Patients with Inflammatory Bowel Disease","volume":"34","author":"Erzin","year":"2023","journal-title":"Turk. J. Gastroenterol."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Haskey, N., Shim, R.C.K., Davidson-Hunt, A., Ye, J., Singh, S., Dieleman, L.A., Jacobson, K., Ghosh, S., and Gibson, D.L. (2022). Dietary adherence to the Mediterranean diet pattern in a randomized clinical trial of patients with quiescent ulcerative colitis. Front. Nutr., 9.","DOI":"10.3389\/fnut.2022.1080156"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/S2468-1253(21)00097-2","article-title":"The role of precision nutrition in the modulation of microbial composition and function in people with inflammatory bowel disease","volume":"6","author":"Sasson","year":"2021","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.2147\/JIR.S349502","article-title":"Adherence to the Mediterranean Diet Improved Clinical Scores and Inflammatory Markers in Children with Active Inflammatory Bowel Disease: A Randomized Trial","volume":"15","author":"Elashry","year":"2022","journal-title":"J. Inflamm. Res."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"s1","DOI":"10.1136\/gutjnl-2019-318484","article-title":"British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults","volume":"68","author":"Lamb","year":"2019","journal-title":"Gut"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s11894-019-0705-6","article-title":"Evolving Epidemiology of IBD","volume":"21","author":"Windsor","year":"2019","journal-title":"Curr. Gastroenterol. Rep."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Flynn, M.M., Tierney, A., and Itsiopoulos, C. (2023). Is Extra Virgin Olive Oil the Critical Ingredient Driving the Health Benefits of a Mediterranean Diet? A Narrative Review. Nutrients, 15.","DOI":"10.3390\/nu15132916"},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Zabetakis, I., Tsoupras, A., Lordan, R., and Ramji, D. (2023). Chapter 4\u2014Olive oil. Functional Foods and Their Implications for Health Promotion, Academic Press.","DOI":"10.1016\/B978-0-12-823811-0.00003-1"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1038\/s41467-020-15646-6","article-title":"Dietary lipids fuel GPX4-restricted enteritis resembling Crohn\u2019s disease","volume":"11","author":"Mayr","year":"2020","journal-title":"Nat. Commun."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"2055441","DOI":"10.1080\/19490976.2022.2055441","article-title":"A Mediterranean-like fat blend protects against the development of severe colitis in the mucin-2 deficient murine model","volume":"14","author":"Haskey","year":"2022","journal-title":"Gut Microbes"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s11746-016-2943-1","article-title":"Comparative Fingerprint Changes of Toxic Volatiles in Low PUFA Vegetable Oils Under Deep-Frying","volume":"94","author":"Santos","year":"2017","journal-title":"JAOCS J. Am. Oil Chem. Soc."},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Jimenez-Lopez, C., Carpena, M., Louren\u00e7o-Lopes, C., Gallardo-Gomez, M., Lorenzo, J.M., Barba, F.J., Prieto, M.A., and Simal-Gandara, J. (2020). Bioactive compounds and quality of extra virgin olive oil. Foods, 9.","DOI":"10.3390\/foods9081014"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1017\/jns.2016.41","article-title":"Flavonoids: An overview","volume":"5","author":"Panche","year":"2016","journal-title":"J. Nutr. Sci."},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Man, A.W.C., Zhou, Y., Xia, N., and Li, H. (2020). Involvement of gut microbiota, microbial metabolites and interaction with polyphenol in host immunometabolism. Nutrients, 12.","DOI":"10.3390\/nu12103054"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jcm.2016.08.008","article-title":"Health Benefits of Dietary Whole Grains: An Umbrella Review of Meta-analyses","volume":"16","author":"McRae","year":"2017","journal-title":"J. Chiropr. Med."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"2742","DOI":"10.1111\/1541-4337.12728","article-title":"Health benefits of whole grain: Effects on dietary carbohydrate quality, the gut microbiome, and consequences of processing","volume":"20","author":"Seal","year":"2021","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/star.201000099","article-title":"Resistant starch as prebiotic: A review","volume":"63","author":"Sendra","year":"2011","journal-title":"Starch St\u00e4rke"},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Haskey, N., Gold, S.L., Faith, J.J., and Raman, M. (2023). To Fiber or Not to Fiber: The Swinging Pendulum of Fiber Supplementation in Patients with Inflammatory Bowel Disease. Nutrients, 15.","DOI":"10.3390\/nu15051080"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1093\/advances\/nmac077","article-title":"Consumption of Nuts and Seeds and Health Outcomes Including Cardiovascular Disease, Diabetes and Metabolic Disease, Cancer, and Mortality: An Umbrella Review","volume":"13","author":"Balakrishna","year":"2022","journal-title":"Adv. Nutr."},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Creedon, A.C., Hung, E.S., Berry, S.E., and Whelan, K. (2020). Nuts and their effect on gut microbiota, gut function and symptoms in adults: A systematic review and meta-analysis of randomised controlled trials. Nutrients, 12.","DOI":"10.3390\/nu12082347"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"174","DOI":"10.26574\/maedica.2023.18.2.174","article-title":"Impact of Dietary Patterns in Inflammatory Bowel Disease Subtypes","volume":"18","author":"Preda","year":"2023","journal-title":"Maedica"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"13486","DOI":"10.1021\/acs.jafc.0c04387","article-title":"Phytochemicals in Legumes: A Qualitative Reviewed Analysis","volume":"68","author":"Mattivi","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/nyas.13312","article-title":"Can pulses play a role in improving cardiometabolic health? Evidence from systematic reviews and meta-analyses","volume":"1392","author":"Viguiliouk","year":"2017","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1111\/apt.16549","article-title":"Systematic review with meta-analysis: Dietary intake in adults with inflammatory bowel disease","volume":"54","author":"Lambert","year":"2021","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1080\/07315724.2020.1800532","article-title":"The Effects of Dairy Product and Dairy Protein Intake on Inflammation: A Systematic Review of the Literature","volume":"40","author":"Nieman","year":"2021","journal-title":"J. Am. Coll. Nutr."},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Kempinski, R., Arabasz, D., and Neubauer, K. (2024). Effects of Milk and Dairy on the Risk and Course of Inflammatory Bowel Disease versus Patients\u2019 Dietary Beliefs and Practices: A Systematic Review. Nutrients, 16.","DOI":"10.3390\/nu16152555"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"18","DOI":"10.7812\/TPP\/18-107","article-title":"Westernized Diet is the Most Ubiquitous Environmental Factor in Inflammatory Bowel Disease","volume":"23","author":"Chiba","year":"2019","journal-title":"Perm. J."},{"key":"ref_78","doi-asserted-by":"crossref","unstructured":"Jia, X., Hu, C., Wu, X., Qi, H., Lin, L., Xu, M., Xu, Y., Wang, T., Zhao, Z., and Chen, Y. (2023). Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bowel Disease via Circulating Metabolites: A Mediation Mendelian Randomization Study. Metabolites, 13.","DOI":"10.3390\/metabo13101041"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"130874","DOI":"10.1016\/j.foodchem.2021.130874","article-title":"A critical review on the health benefits of fish consumption and its bioactive constituents","volume":"369","author":"Chen","year":"2022","journal-title":"Food Chem."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1017\/S1368980017000234","article-title":"The un Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing","volume":"21","author":"Monteiro","year":"2018","journal-title":"Public Health Nutr."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1093\/nutrit\/nuad101","article-title":"The association of ultra-processed food consumption with adult inflammatory bowel disease risk: A systematic review and dose-response meta-analysis of 4035694 participants","volume":"82","author":"Babaei","year":"2024","journal-title":"Nutr. Rev."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"832","DOI":"10.14309\/ajg.0000000000000608","article-title":"Effect of Lifestyle Factors on Outcomes in Patients with Inflammatory Bowel Diseases","volume":"115","author":"Rozich","year":"2020","journal-title":"Am. J. Gastroenterol."},{"key":"ref_83","first-page":"211","article-title":"Alcohol use in patients with inflammatory bowel disease","volume":"17","author":"Ramos","year":"2021","journal-title":"Gastroenterol. Hepatol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/j.cgh.2020.01.046","article-title":"Dietary Guidance From the International Organization for the Study of Inflammatory Bowel Diseases","volume":"18","author":"Levine","year":"2020","journal-title":"Clin. Gastroenterol. 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