{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T02:46:48Z","timestamp":1775098008400,"version":"3.50.1"},"reference-count":44,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T00:00:00Z","timestamp":1738281600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIHR Southampton Clinical Research Facility"},{"name":"National Institute for Health for the Southampton Health Research Biomedical Research Unit"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: In chronic kidney disease (CKD), poor nutrition is associated with poorer clinical outcomes. There are limited data on milder stages of childhood CKD. Methods: This study characterised the nutritional state of a cohort of children with CKD. Results: Within the cohort (mean age 10.5 years, mean eGFR = 57 mL\/min\/1.73 m2), obesity defined by body mass index rates was comparable to that in the general population, but central obesity (waist-to-height ratio &gt; 0.5) was evident in 44% of children. Although average nutrient intakes for the cohort were acceptable, there was marked variability in the risk of poor nutrient intake (&lt;LRNI): selenium (35%), magnesium (35%), iodine (30%), and zinc (30%). No child met the recommended dietary fibre intake. The prevalence of frank deficiency of vitamins and minerals in blood concentrations was low. Blood concentrations of vitamins A and E were near-universally elevated. In those who had a decline in kidney function at the 12-month follow-up, dietary intake of fibre correlated with the degree of decline. Conclusions: Much work is needed to optimise the nutritional status of children with CKD as an important modifiable risk factor for disease progression and other important outcomes.<\/jats:p>","DOI":"10.3390\/nu17030535","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T08:05:41Z","timestamp":1738310741000},"page":"535","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Nutritional Characterisation of Childhood Chronic Kidney Disease: Trace Element Malnutrition in Paediatric Renal Disease (TeMPeReD) Study"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2977-0263","authenticated-orcid":false,"given":"Matthew J.","family":"Harmer","sequence":"first","affiliation":[{"name":"Southampton Children\u2019s Hospital, Southampton SO16 6YD, UK"},{"name":"School of Development and Health, Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9495-9719","authenticated-orcid":false,"given":"Stephen A.","family":"Wootton","sequence":"additional","affiliation":[{"name":"School of Development and Health, Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodney D.","family":"Gilbert","sequence":"additional","affiliation":[{"name":"Southampton Children\u2019s Hospital, Southampton SO16 6YD, UK"},{"name":"School of Development and Health, Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline E.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Southampton Children\u2019s Hospital, Southampton SO16 6YD, UK"},{"name":"School of Development and Health, Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s00467-011-1939-1","article-title":"Epidemiology of chronic kidney disease in children","volume":"27","author":"Harambat","year":"2012","journal-title":"Pediatr. 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