{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:44:51Z","timestamp":1792806291455,"version":"4.5.0"},"reference-count":51,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Peking University Medical-Qingyan Boshi Joint Laboratory","award":["L202206"],"award-info":[{"award-number":["L202206"]}],"id":[{"id":"https:\/\/ror.org\/02v51f717","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Peking University Medical-Qingyan Boshi Joint Laboratory","award":["YFF24000662"],"award-info":[{"award-number":["YFF24000662"]}],"id":[{"id":"https:\/\/ror.org\/02v51f717","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Peking University Medical-Qingyan Boshi Joint Laboratory","award":["BSU20240500"],"award-info":[{"award-number":["BSU20240500"]}],"id":[{"id":"https:\/\/ror.org\/02v51f717","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Peking University Health Science Center","award":["L202206"],"award-info":[{"award-number":["L202206"]}],"id":[{"id":"https:\/\/ror.org\/02v51f717","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Peking University Health Science Center","award":["YFF24000662"],"award-info":[{"award-number":["YFF24000662"]}],"id":[{"id":"https:\/\/ror.org\/02v51f717","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Peking University Health Science Center","award":["BSU20240500"],"award-info":[{"award-number":["BSU20240500"]}],"id":[{"id":"https:\/\/ror.org\/02v51f717","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: This study investigated the effects of combined Rhodiola rosea (RHO) and caffeine (CAF) supplementation on lower limb explosive power and fatigue recovery in volleyball players, aiming to validate their potential synergistic effects. Methods: A randomized, double-blind, placebo-controlled design was implemented involving 48 male volleyball athletes allocated into four groups: placebo (CTR), Rhodiola rosea (RHO), caffeine (CAF), and combined (RHO + CAF). Over four weeks, participants engaged in twice-weekly high-intensity lower limb resistance training, with performance evaluated through multiple tests, including two-step-approach jump height, countermovement jump (CMJ), five-jump test (5 JT), continuous 20 vertical jumps, and intermittent jump recovery alongside Rate of Perceived Exertion (RPE) assessments. Results: Results showed that the combined supplementation (RHO + CAF) group exhibited significant improvement across multiple performance metrics. In particular, the combined group demonstrated the highest increases in jump height and the least power decline during high-frequency jumps, outperforming the CTR and other supplementation groups (p &lt; 0.05). Additionally, RHO + CAF supplementation significantly lowered RPE scores, particularly in the final week of training, indicating improved perceived fatigue and recovery. Conclusions: This study suggests that combining RHO and CAF optimizes high-intensity performance by enhancing explosive power, reducing fatigue, and improving recovery, presenting an effective nutritional strategy for volleyball athletes.<\/jats:p>","DOI":"10.3390\/nu17040681","type":"journal-article","created":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T06:52:01Z","timestamp":1739515921000},"page":"681","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effects of the Combined Supplementation of Caffeine and Rhodiola Rosea with Resistance Training on Lower Limb Explosive Power in Male Volleyball Players"],"prefix":"10.3390","volume":"17","author":[{"given":"Zhaolong","family":"Wang","sequence":"first","affiliation":[{"name":"Chinese College of Volleyball, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyu","family":"Du","sequence":"additional","affiliation":[{"name":"Chinese College of Volleyball, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6768-4884","authenticated-orcid":false,"given":"Huixin","family":"Li","sequence":"additional","affiliation":[{"name":"School of Sport Science, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Zhao","sequence":"additional","affiliation":[{"name":"Chinese College of Volleyball, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingran","family":"Zhao","sequence":"additional","affiliation":[{"name":"Chinese College of Volleyball, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifei","family":"Ma","sequence":"additional","affiliation":[{"name":"Chinese College of Volleyball, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiashuo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Chinese College of Volleyball, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangshuo","family":"Wu","sequence":"additional","affiliation":[{"name":"Chinese College of Volleyball, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Jiang","sequence":"additional","affiliation":[{"name":"Chinese College of Volleyball, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7867-6807","authenticated-orcid":false,"given":"Chang","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Sport Science, Beijing Sport University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Yun, H., Lu, B., Su, W., Wang, J., Zheng, J., Wang, J., Wang, Z., Li, Y., Sun, Y., and Liu, C. (2024). Combined effects of Rhodiola rosea and caffeine supplementation on aerobic endurance and muscle explosiveness: A synergistic approach. Front. Nutr., 11.","DOI":"10.3389\/fnut.2024.1335950"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1017\/S0007114523001988","article-title":"Rhodiola rosea as an adaptogen to enhance exercise performance: A review of the literature","volume":"131","author":"Tinsley","year":"2024","journal-title":"Br. J. Nutr."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"4414","DOI":"10.1002\/ptr.7950","article-title":"Rhodiola rosea supplementation on sports performance: A systematic review of randomized controlled trials","volume":"37","author":"Noreen","year":"2023","journal-title":"Phytother. Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1139\/apnm-2016-0547","article-title":"The effect of caffeine on skeletal muscle anabolic signaling and hypertrophy","volume":"42","author":"Moore","year":"2017","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1079\/NRR2006122","article-title":"Nutritional supplements: Prevalence of use and contamination with doping agents","volume":"19","author":"Delbeke","year":"2006","journal-title":"Nutr. Res. Rev."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Marcinek, K., Luzak, B., and Rozalski, M. (2024). The Effects of Caffeine on Blood Platelets and the Cardiovascular System through Adenosine Receptors. Int. J. Mol. Sci., 25.","DOI":"10.20944\/preprints202406.1844.v1"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Liu, C., Zhao, H., Yan, Y., Yang, W., Chen, S., Song, G., Li, X., Gu, Y., Yun, H., and Li, Y. (2023). Synergistic Effect of Rhodiola rosea and Caffeine Supplementation on the Improvement of Muscle Strength and Muscular Endurance: A Pilot Study for Rats, Resistance Exercise-Untrained and -Trained Volunteers. Nutrients, 15.","DOI":"10.3390\/nu15030582"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Liu, C., Lib, Y., Song, G., Li, X., Chen, S., Zou, D., and Li, H. (2023). Caffeine promotes the production of Irish in muscles and thus facilitates the browning of white adipose tissue. J. Funct. Foods, 108.","DOI":"10.1016\/j.jff.2023.105702"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1152\/physiol.00038.2018","article-title":"High-intensity exercise and mitochondrial biogenesis: Current controversies and future research directions","volume":"34","author":"Bishop","year":"2019","journal-title":"Physiology"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Huang, B., Cheng, X., Wang, D., Peng, M., Xue, Z., Da, Y., Zhang, N., Yao, Z., Li, M., and Xu, A. (2014). Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK\/Sirt1\/PGC-1\u03b1 signaling. Oncotarget, 5.","DOI":"10.18632\/oncotarget.1963"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.phymed.2018.10.031","article-title":"Salidroside stimulates the Sirt1\/PGC-1\u03b1 axis and ameliorates diabetic nephropathy in mice","volume":"54","author":"Xue","year":"2019","journal-title":"Phytomedicine"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ejphar.2012.01.027","article-title":"Salidroside stimulates the accumulation of HIF-1\u03b1 protein resulted in the induction of EPO expression: A signaling via blocking the degradation pathway in kidney and liver cells","volume":"679","author":"Zheng","year":"2012","journal-title":"Eur. J. Pharmacol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"486","DOI":"10.3177\/jnsv.55.486","article-title":"Dissociation between PGC-1alpha and GLUT-4 expression in skeletal muscle of rats fed a high-fat diet","volume":"55","author":"Higashida","year":"2009","journal-title":"J. Nutr. Sci. Vitaminol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/s41556-020-0461-8","article-title":"Energy-stress-mediated AMPK activation inhibits ferroptosis","volume":"22","author":"Lee","year":"2020","journal-title":"Nat. Cell Biol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1096\/fj.15-276907","article-title":"Training intensity modulates changes in PGC-1\u03b1 and p53 protein content and mitochondrial respiration, but not markers of mitochondrial content in human skeletal muscle","volume":"30","author":"Granata","year":"2016","journal-title":"FASEB J."},{"key":"ref_16","unstructured":"USDA National Nutrient Database for Standard Reference (2025, January 25). U.S. Department of Agriculture. Agricultural Research Service, Available online: https:\/\/fdc.nal.usda.gov."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1123\/ijspp.2013-0448","article-title":"Enhancing physical performance in male volleyball players with a caffeine-containing energy drink","volume":"9","author":"Salinero","year":"2014","journal-title":"Int. J. Sports Physiol. Perform."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Zhu, H., Zhao, H., Qian, H., and Liu, C. (2024). Urolithin A Ameliorates Athletic Ability and Intestinal Microbiota in Sleep Deprivation from the Perspective of the Gut-Muscle Axis. Mol. Nutr. Food Res., 68.","DOI":"10.1002\/mnfr.202300599"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Dun, Y., Liu, S., Zhang, W., Xie, M., and Qiu, L. (2017). Exercise combined with Rhodiola sacra supplementation improves exercise capacity and ameliorates exhaustive exer-cise-induced muscle damage through enhancement of mitochondrial quality control. Oxidative Med. Cell. Longev., 2017.","DOI":"10.1155\/2017\/8024857"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Fu, H., Zhang, Y., An, Q., Wang, D., You, S., Zhao, D., Zhang, J., Wang, C., and Li, M. (2022). Anti-photoaging effect of Rhodiola rosea fermented by Lactobacillus plantarum on UVA-damaged fibroblasts. Nutrients, 14.","DOI":"10.3390\/nu14112324"},{"key":"ref_21","first-page":"3161","article-title":"Rhodiola Crenulata ameliorates exhaustive exercise-induced fatigue in mice by suppressing mitophagy in skeletal muscle","volume":"20","author":"Hou","year":"2020","journal-title":"Exp. Ther. Med."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Fu, S., Meng, Y., Zhang, W., Wang, J., He, Y., Huang, L., Chen, H., Kuang, J., and Du, H. (2019). Transcriptomic responses of skeletal muscle to acute exercise in diabetic Goto-Kakizaki rats. Front. Physiol., 10.","DOI":"10.3389\/fphys.2019.00872"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Zhang, Z.-H., Zhu, W., Ren, H.-Z., Zhao, X., Wang, S., Ma, H.-C., and Shi, X.-L. (2017). Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure. Stem Cell Res. Ther., 8.","DOI":"10.1186\/s13287-017-0524-3"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1038\/jcbfm.2009.50","article-title":"Enhanced cerebral expression of MCT1 and MCT2 in a rat ischemia model occurs in activated microglial cells","volume":"29","author":"Moreira","year":"2009","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1007\/s00421-017-3731-9","article-title":"Effects of normoxic and hypoxic exercise regimens on lymphocyte apoptosis induced by oxidative stress in sedentary males","volume":"117","author":"Wang","year":"2017","journal-title":"Eur. J. Appl. Physiol."},{"key":"ref_26","first-page":"16","article-title":"Association of free radicals and the tissue renin-angiotensin system: Prospective effects of Rhodiola, a genus of Chinese herb, on hypoxia-induced pancreatic injury","volume":"2","author":"Ip","year":"2001","journal-title":"JOP J. Pancreas"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"316","DOI":"10.4077\/CJP.2009.AMH029","article-title":"Attenuation of long-term Rhodiola rosea supplementation on exhaustive swimming-evoked oxidative stress in the rat","volume":"52","author":"Huang","year":"2009","journal-title":"Chin. J. Physiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1142\/S0192415X09007053","article-title":"Chronic Rhodiola rosea extract supplementation enforces exhaustive swimming tolerance","volume":"37","author":"Lee","year":"2009","journal-title":"Am. J. Chin. Med."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Guest, N.S., VanDusseldorp, T.A., Nelson, M.T., Grgic, J., Schoenfeld, B.J., Jenkins, N.D.M., Arent, S.M., Antonio, J., Stout, J.R., and Trexler, E.T. (2021). International society of sports nutrition position stand: Caffeine and exercise performance. J. Int. Soc. Sports Nutr., 18.","DOI":"10.1186\/s12970-020-00383-4"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Wang, Z., Qiu, B., Gao, J., and Del Coso, J. (2022). Effects of caffeine intake on endurance running performance and time to exhaustion: A sys-tematic review and Meta-analysis. Nutrients, 15.","DOI":"10.3390\/nu15010148"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.pbb.2014.03.027","article-title":"Acute intraperitoneal injection of caffeine improves endurance exercise performance in association with increasing brain dopamine release during exercise","volume":"122","author":"Zheng","year":"2014","journal-title":"Pharmacol. Biochem. Behav."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0031-6997(24)01396-6","article-title":"Actions of caffeine in the brain with special reference to factors that contribute to its widespread use","volume":"51","author":"Fredholm","year":"1999","journal-title":"Pharmacol. Rev."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1046\/j.1471-4159.2003.02245.x","article-title":"Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure","volume":"88","author":"Quarta","year":"2004","journal-title":"J. Neurochem."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/S0278-6915(02)00096-0","article-title":"Effects of caffeine on human behavior","volume":"40","author":"Smith","year":"2002","journal-title":"Food Chem. Toxicol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0304-3940(96)12780-4","article-title":"Adenosine A1 and A2 receptors modulate extracellular dopamine levels in rat striatum","volume":"212","author":"Okada","year":"1998","journal-title":"Neurosci. Lett."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2174\/1570159X13666141210215655","article-title":"Caffeine: Cognitive and physical performance enhancer or psychoactive drug?","volume":"13","author":"Cappelletti","year":"2015","journal-title":"Curr. Neuropharmacol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1007\/s00726-014-1709-z","article-title":"Caffeine-containing energy drink improves physical performance in female soccer players","volume":"46","author":"Lara","year":"2014","journal-title":"Amino Acids"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1007\/s00726-013-1473-5","article-title":"Caffeine-containing energy drink improves sprint performance during an international rugby sevens competition","volume":"44","author":"Portillo","year":"2013","journal-title":"Amino Acids"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.1519\/JSC.0000000000001763","article-title":"Effects of caffeine ingestion on skill performance during an international female Rugby sevens competition","volume":"31","author":"Portillo","year":"2017","journal-title":"J. Strength Cond. Res."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1249\/MSS.0b013e3181cabbd8","article-title":"Effect of caffeine ingestion on muscular strength and endurance: A meta-analysis","volume":"42","author":"Warren","year":"2010","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1249\/MSS.0000000000001596","article-title":"Caffeine, CYP1A2 genotype, and endurance performance in athletes","volume":"50","author":"Guest","year":"2018","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_42","first-page":"E394","article-title":"Skeletal muscle PGC-1\u03b2 signaling is sufficient to drive an endurance exercise phenotype and to counteract components of detraining in mice","volume":"312","author":"Lee","year":"2017","journal-title":"Am. J. Physiol. Metab."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"860","DOI":"10.2337\/db07-0843","article-title":"AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5","volume":"57","author":"McGee","year":"2008","journal-title":"Diabetes"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1152\/japplphysiol.00416.2006","article-title":"Increased submaximal insulin-stimulated glucose uptake in mouse skeletal muscle after treadmill exercise","volume":"101","author":"Hamada","year":"2006","journal-title":"J. Appl. Physiol. (1985)"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Baird, L., and Yamamoto, M. (2020). The molecular mechanisms regulating the KEAP1-NRF2 pathway. Mol. Cell. Biol., 40.","DOI":"10.1128\/MCB.00099-20"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Serafini, M.M., Catanzaro, M., Fagiani, F., Simoni, E., Caporaso, R., Dacrema, M., Romanoni, I., Govoni, S., Racchi, M., and Daglia, M. (2019). Modulation of Keap1\/Nrf2\/ARE signaling pathway by Curcuma- and garlic-derived hybrids. Front. Pharmacol., 10.","DOI":"10.3389\/fphar.2019.01597"},{"key":"ref_47","first-page":"705","article-title":"Candidate mechanisms of caffeine improving memory dysfunction","volume":"74","author":"Alhowail","year":"2019","journal-title":"Die Pharm."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1139\/apnm-2018-0671","article-title":"Acute caffeine supplementation promotes small to moderate improvements in performance tests indicative of in-game success in professional female basketball players","volume":"44","author":"Scanlan","year":"2019","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Punja, S., Shamseer, L., Olson, K., and Vohra, S. (2014). Rhodiola rosea for mental and physical fatigue in nursing students: A randomized controlled trial. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0108416"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1152\/japplphysiol.01108.2018","article-title":"Effects of caffeine and sex on muscle performance and delayed-onset muscle soreness after exercise-induced muscle damage: A double-blind randomized trial","volume":"127","author":"Chen","year":"2019","journal-title":"J. Appl. Physiol. (1985)"},{"key":"ref_51","unstructured":"American College of Sports Medicine (ACSM) (2018). ACSM\u2019s Guidelines for Exercise Testing and Prescription, Lippincott Williams & Wilkins. [10th ed.]."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/17\/4\/681\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:34:14Z","timestamp":1760027654000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/17\/4\/681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,14]]},"references-count":51,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["nu17040681"],"URL":"https:\/\/doi.org\/10.3390\/nu17040681","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,14]]}}}