{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:01:49Z","timestamp":1790787709729,"version":"4.1.0"},"reference-count":19,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Objectives: This study examines the mediating role of nutritional intake in the relationship between tooth loss and healthy ageing in older American adults. Methods: A secondary data analysis was conducted using the Health and Retirement Study (HRS), a longitudinal survey of American older adults aged 50 years and over. Data from six waves from 2006 to 2016 were used. Nutritional intake was assessed in 2013 using ten essential nutrients, categorised as adequate or inadequate based on national dietary recommendations. Healthy ageing was an aggregate variable composed of freedom from cognitive impairment, freedom from disability, and high physical functioning. Tooth loss was measured as a dichotomous variable (edentate\/dentate). Structural equation modelling was used to assess the associations between tooth loss in 2012, nutrition in 2013, and healthy ageing in 2016, accounting for demographic\/socioeconomic factors and behaviours. Results: A total of 3665 participants were included on the analysis. A significant association was found between being dentate in 2012 and nutritional intake in 2013 (coefficient 0.63: 95% CI: 0.62, 0.54, p &lt; 0.001). Healthy ageing in 2016 was significantly influenced by socioeconomic factors in 2006 (coefficient 0.84: 95% CI: 1.38, 1.42, p &lt; 0.001) and nutrition in 2013 (coefficient 0.05: 95% CI: 0.04, 0.05, p &lt; 0.001). Non-Black individuals showed a significant association with healthy ageing. Conclusions: The findings underscore the complex interplay of nutrition, socioeconomic status, health behaviours, and oral health in predicting healthy ageing trajectories. This study highlights the importance of oral health to maintaining adequate nutritional intake, which in turn promotes healthy ageing.<\/jats:p>","DOI":"10.3390\/nu17040719","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T08:36:19Z","timestamp":1739867779000},"page":"719","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The Nutritional Pathway Between Tooth Loss and Healthy Ageing: A Longitudinal Study of Older American Adults"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5649-8421","authenticated-orcid":false,"given":"Lujain","family":"Sahab","sequence":"first","affiliation":[{"name":"Faculty of Dentistry, Oral and Craniofacial Research, King\u2019s College London, London SE5 8AF, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4082-6942","authenticated-orcid":false,"given":"Jonathon","family":"Newton","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Oral and Craniofacial Research, King\u2019s College London, London SE5 8AF, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6339-9480","authenticated-orcid":false,"given":"Wael","family":"Sabbah","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Oral and Craniofacial Research, King\u2019s College London, London SE5 8AF, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e96289","DOI":"10.1371\/journal.pone.0096289","article-title":"Measuring the speed of aging across population subgroups","volume":"9","author":"Sanderson","year":"2014","journal-title":"PLoS ONE"},{"key":"ref_2","unstructured":"WHO (2024). Ageing and Health, WHO. Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/ageing-and-health."},{"key":"ref_3","unstructured":"Vespa, J., Medina, L., and Armstrong, D.M. (2020). Demographic Turning Points for the United States: Population Projections for 2020 to 2060."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1016\/S0140-6736(09)61460-4","article-title":"Ageing populations: The challenges ahead","volume":"374","author":"Christensen","year":"2009","journal-title":"Lancet"},{"key":"ref_5","first-page":"359","article-title":"Definitions of successful ageing: A brief review of a multidimensional concept","volume":"90","author":"Urtamo","year":"2019","journal-title":"Acta Biomed."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1093\/advances\/nmab032","article-title":"Healthy Aging-Nutrition Matters: Start Early and Screen Often","volume":"12","author":"Roberts","year":"2021","journal-title":"Adv. Nutr."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1111\/joim.13728","article-title":"Diet strategies for promoting healthy aging and longevity: An epidemiological perspective","volume":"295","author":"Hu","year":"2024","journal-title":"J. Intern. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.cger.2020.06.008","article-title":"Nutrition and Healthy Aging","volume":"36","author":"Black","year":"2020","journal-title":"Clin. Geriatr. Med."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Dominguez, L.J., Veronese, N., Baiamonte, E., Guarrera, M., Parisi, A., Ruffolo, C., Tagliaferri, F., and Barbagallo, M. (2022). Healthy Aging and Dietary Patterns. Nutrients, 14.","DOI":"10.3390\/nu14040889"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Zhou, Y.F., Song, X.Y., Pan, A., and Koh, W.P. (2023). Nutrition and Healthy Ageing in Asia: A Systematic Review. Nutrients, 15.","DOI":"10.3390\/nu15143153"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.identj.2022.06.001","article-title":"Oral Health for Healthy Ageing: A People-centred and Function-focused Approach","volume":"72","author":"Fukai","year":"2022","journal-title":"Int. Dent. J."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Chan, A.K.Y., Tsang, Y.C., Jiang, C.M., Leung, K.C.M., Lo, E.C.M., and Chu, C.H. (2023). Diet, Nutrition, and Oral Health in Older Adults: A Review of the Literature. Dent. J., 11.","DOI":"10.3390\/dj11090222"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/ger.12510","article-title":"Oral health and healthy chewing for healthy cognitive ageing: A comprehensive narrative review","volume":"38","author":"Catena","year":"2021","journal-title":"Gerodontology"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.jamda.2023.01.009","article-title":"Socioeconomic and Ethnic Inequalities in the Progress of Multimorbidity and the Role of Health Behaviors","volume":"24","author":"Mira","year":"2023","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1093\/gerona\/glr234","article-title":"An examination of healthy aging across a conceptual continuum: Prevalence estimates, demographic patterns, and validity","volume":"67","author":"Mclaughlin","year":"2012","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Byrne, B.M. (2013). Structural Equation Modeling with Mplus Basic Concepts, Applications, and Programming, Taylor and Francis.","DOI":"10.4324\/9780203807644"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"101365","DOI":"10.1016\/j.arr.2021.101365","article-title":"Socioeconomic position and healthy ageing: A systematic review of cross-sectional and longitudinal studies","volume":"69","author":"Wagg","year":"2021","journal-title":"Ageing Res. Rev."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1002\/jcsm.13174","article-title":"Causal linkage of tobacco smoking with ageing: Mendelian randomization analysis towards telomere attrition and sarcopenia","volume":"14","author":"Park","year":"2023","journal-title":"J. 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