{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:01:28Z","timestamp":1787029288694,"version":"build-2736575974"},"reference-count":84,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Objectives: Dietary habits are identified as a potential factor influencing the quality of life of individuals diagnosed with Hashimoto\u2019s disease (HAT). The objective of this study was to analyze the relationship between quality of diet and selected parameters of nutritional status, and quality of life in female patients with HAT. Methods: A descriptive cross-sectional study was conducted among 147 women aged 39.9 \u00b1 10.39 years. Diet quality was determined with the Pro-Healthy Diet Index (pHDI-10), quality of life with a thyroid-specific questionnaire (ThyPROpl), and gastrointestinal symptoms with the Gastrointestinal Symptom Rating Scale (GSRS). Results: The mean pHDI-10 score was 25.5 \u00b1 9.59; 80% of women had a low pro-healthy diet quality (LQD group, 21.9 \u00b1 6,89 pts.) and 20% had a medium pro-healthy diet quality (MQD group, 39.7 \u00b1 4.69 pts.). Nutritional status and anthropometric and health risk parameters did not differ between the groups. The ThyPROpl score was 49.15 \u00b1 31.16 (LQD: 49.58 \u00b1 31.01, MQD: 47.41 \u00b1 32.28, p = 0.73). Conclusions: Quality of diet was not associated with the quality of life or nutritional status of HAT patients. However, the majority of participants showed poor healthy eating habits, elevated body mass index and unsatisfactory quality of life in areas, such as tiredness, hypothyroid symptoms, depression, emotional vulnerability, and anxiety.<\/jats:p>","DOI":"10.3390\/nu17061015","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T04:29:18Z","timestamp":1741926558000},"page":"1015","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["No Association Between Diet Quality, Nutritional Status, and Quality of Life in Women with Hashimoto\u2019s Thyroiditis\u2014A Cross-Sectional Study"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9087-067X","authenticated-orcid":false,"given":"Karolina","family":"Osowiecka","sequence":"first","affiliation":[{"name":"Department of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (WULS), 02-776 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5643-6899","authenticated-orcid":false,"given":"Damian","family":"Skrypnik","sequence":"additional","affiliation":[{"name":"Department of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznan University of Medical Sciences, 60-355 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7167-1993","authenticated-orcid":false,"given":"Joanna","family":"Myszkowska-Ryciak","sequence":"additional","affiliation":[{"name":"Department of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (WULS), 02-776 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,14]]},"reference":[{"key":"ref_1","unstructured":"Departament Bada\u0144 Spo\u0142ecznych (2025, January 10). Stan Zdrowia Ludno\u015bci Polski w 2019. G\u0142\u00f3wny Urz\u0105d Statystyczny, Warsaw, (In Polish)."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Hu, X., Chen, Y., Shen, Y., Tian, R., Sheng, Y., and Que, H. (2022). Global prevalence and epidemiological trends of Hashimoto\u2019s thyroiditis in adults: A systematic review and meta-analysis. Front. Public Health, 10.","DOI":"10.3389\/fpubh.2022.1020709"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s40618-020-01477-1","article-title":"An update on the pathogenesis of Hashimoto\u2019s thyroiditis","volume":"44","author":"Weetman","year":"2021","journal-title":"J. Endocrinol. Investig."},{"key":"ref_4","first-page":"16222","article-title":"Hashimoto thyroiditis: An evidence-based guide to etiology, diagnosis and treatment","volume":"132","author":"Wartofsky","year":"2022","journal-title":"Pol. Arch. Intern. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.kjms.2016.06.006","article-title":"Autoimmunity affects health-related quality of life in patients with Hashimoto\u2019s thyroiditis","volume":"32","author":"Ayhan","year":"2016","journal-title":"Kaohsiung J. Med. Sci."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"100101","DOI":"10.1016\/j.jtauto.2021.100101","article-title":"Persisting symptoms in patients with Hashimoto\u2019s disease despite normal thyroid hormone levels: Does thyroid autoimmunity play a role? A systematic review","volume":"4","author":"Groenewegen","year":"2021","journal-title":"J. Transl. Autoimmun."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s12020-018-1649-6","article-title":"Cognitive functioning and quality of life in patients with Hashimoto thyroiditis on long-term levothyroxine replacement","volume":"62","author":"Djurovic","year":"2018","journal-title":"Endocrine"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.11124\/JBIES-20-00043","article-title":"Association between anti-thyroid antibodies and quality of life in patients with Hashimoto thyroiditis: A systematic review and meta-analysis","volume":"19","author":"Patti","year":"2021","journal-title":"JBI Evid. Synth."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Ruggeri, R.M., Barbalace, M.C., Croce, L., Malaguti, M., Campenn\u00ec, A., Rotondi, M., Cannav\u00f2, S., and Hrelia, S. (2023). Autoimmune Thyroid Disorders: The Mediterranean Diet as a Protective Choice. Nutrients, 15.","DOI":"10.3390\/nu15183953"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1186\/s12955-020-01581-z","article-title":"A systematic review of the association between dietary patterns and health-related quality of life","volume":"18","author":"Vajdi","year":"2020","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Matana, A., Torlak, V., Brdar, D., Popovi\u0107, M., Lozi\u0107, B., Barbali\u0107, M., Perica, V.B., Punda, A., Pola\u0161ek, O., and Hayward, C. (2017). Dietary Factors Associated with Plasma Thyroid Peroxidase and Thyroglobulin Antibodies. Nutrients, 9.","DOI":"10.3390\/nu9111186"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Song, R.H., Wang, B., Yao, Q.M., Li, Q., Jia, X., and Zhang, J.A. (2019). The Impact of Obesity on Thyroid Autoimmunity and Dysfunction: A Systematic Review and Meta-Analysis. Front. Immunol., 10.","DOI":"10.3389\/fimmu.2019.02349"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Danailova, Y., Velikova, T., Nikolaev, G., Mitova, Z., Shinkov, A., Gagov, H., and Konakchieva, R. (2022). Nutritional Management of Thyroiditis of Hashimoto. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23095144"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Osowiecka, K., and Myszkowska-Ryciak, J. (2023). The Influence of Nutritional Intervention in the Treatment of Hashimoto\u2019s Thyroiditis\u2014A Systematic Review. Nutrients, 15.","DOI":"10.3390\/nu15041041"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Szczuko, M., Syrenicz, A., Szymkowiak, K., Przybylska, A., Szczuko, U., Pob\u0142ocki, J., and Kulpa, D. (2022). Doubtful Justification of the Gluten-Free Diet in the Course of Hashimoto\u2019s Disease. Nutrients, 14.","DOI":"10.3390\/nu14091727"},{"key":"ref_16","first-page":"381","article-title":"Successful dietary intervention plan for Hashimoto\u2019s thyroiditis: A case study","volume":"27","year":"2020","journal-title":"Rom. J. Diabetes Nutr. Metab. Dis."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"140","DOI":"10.12775\/JEHS.2023.34.01.012","article-title":"Does a gluten-free diet result in nutritional deficiencies?\u2014A review of literature\u201d","volume":"34","author":"Antkowiak","year":"2023","journal-title":"J. Educ. Health Sport"},{"key":"ref_18","unstructured":"Jezewska-Zychowicz, M., Gawecki, J., Wadolowska, L., Czarnocinska, J., Galinski, G., Kollajtis-Dolowy, A., Roszkowski, W., Wawrzyniak, A., Przybylowicz, K., and Krusinska, B. (2023, July 20). Dietary Habits and Nutrition Beliefs Questionnaire and the Manual for Developing of Nutritional Data. Polish Academy of Sciences. Available online: http:\/\/www.medprew.cm-uj.krakow.pl\/doku\/kwestionariusz_kompan2016.pdf."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Kowalkowska, J., Wadolowska, L., Czarnocinska, J., Czlapka-Matyasik, M., Galinski, G., Jezewska-Zychowicz, M., Bronkowska, M., Dlugosz, A., Loboda, D., and Wyka, J. (2018). Reproducibility of a Questionnaire for Dietary Habits, Lifestyle and Nutrition Knowledge Assessment (KomPAN) in Polish Adolescents and Adults. Nutrients, 10.","DOI":"10.3390\/nu10121845"},{"key":"ref_20","unstructured":"(2024, July 20). Antropometry Procedures Manual, Available online: https:\/\/wwwn.cdc.gov\/nchs\/data\/nhanes\/public\/2017\/manuals\/2017_Anthropometry_Procedures_Manual.pdf."},{"key":"ref_21","unstructured":"(2025, January 10). A Healthy Lifestyle\u2014WHO Recommendations. Available online: https:\/\/www.who.int\/europe\/news-room\/fact-sheets\/item\/a-healthy-lifestyle---who-recommendations."},{"key":"ref_22","unstructured":"(2024, July 20). Waist Circumference and Waist-Hip Ratio, Available online: https:\/\/www.who.int\/publications\/i\/item\/9789241501491."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"431","DOI":"10.3345\/kjp.2016.59.11.425","article-title":"Waist-to-Height Ratio as a Screening Tool for Obesity and Cardiometabolic Risk","volume":"59","author":"Yoo","year":"2016","journal-title":"Korean J. Pediatr."},{"key":"ref_24","first-page":"1","article-title":"Principles of Hypertension Management\u20142019. Guidelines of the Polish Society of Hypertension [Zasady Post\u0119powania w Nadci\u015bnieniu T\u0119tniczym\u20142019 Rok. Wytyczne Polskiego Towarzystwa Nadci\u015bnienia T\u0119tniczego]","volume":"5","author":"Tykarski","year":"2019","journal-title":"Nadci\u015bnienie T\u0119tnicze W Prakt."},{"key":"ref_25","first-page":"367","article-title":"ThyPROpl\u2014The Polish Version of the Thyroid-Specific Quality of Life Questionnaire ThyPRO","volume":"66","author":"Watt","year":"2015","journal-title":"Endokrynol. Pol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1530\/EJE-09-0521","article-title":"Validity and reliability of the novel thyroid-specific quality of life questionnaire, ThyPRO","volume":"162","author":"Watt","year":"2010","journal-title":"Eur. J. Endocrinol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3109\/00365529609095544","article-title":"Relevance of Norm Values as Part of the Documentation of Quality of Life Instruments for Use in Upper Gastrointestinal Disease","volume":"31","author":"Carlsson","year":"1996","journal-title":"Scand. J. Gastroenterol. Suppl."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1477-7525-6-12","article-title":"Reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in dyspepsia: A six-country study","volume":"6","author":"Kulich","year":"2008","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Boushey, C., Ard, J., Bazzano, L., Heymsfield, S., Mayer-Davis, E., Sabat\u00e9, J., Snetselaar, L., Van Horn, L., Schneeman, B., and English, L.K. (2020). Dietary Patterns and Growth, Size, Body Composition, and\/or Risk of Overweight or Obesity: A Systematic Review, U.S. Department of Agriculture, Food and Nutrition Service, Center for Nutrition Policy and Promotion, Nutrition Evidence System.","DOI":"10.52570\/NESR.DGAC2020.SR0101"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1017\/S1368980024001927","article-title":"Identification of Chinese dietary patterns and their relationships with health outcomes: A systematic review and meta-analysis","volume":"27","author":"Hu","year":"2024","journal-title":"Public Health Nutr."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.nutres.2017.01.006","article-title":"A posteriori healthy dietary patterns may decrease the risk of central obesity: Findings from a systematic review and meta-analysis","volume":"41","author":"Rezagholizadeh","year":"2017","journal-title":"Nutr. Res."},{"key":"ref_32","unstructured":"(2025, January 10). Profilaktyka i Leczenie Oty\u0142o\u015bci u Os\u00f3b Doros\u0142ych [Prevention and Treatment of Obesity in Adults]. Najwy\u017csza Izba Kontroli [Supreme Audit Office], (In Polish)."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1186\/s40001-023-01480-1","article-title":"Causal association between body mass index and autoimmune thyroiditis: Evidence from Mendelian randomization","volume":"28","author":"Huo","year":"2023","journal-title":"Eur. J. Med. Res."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"e35951","DOI":"10.1097\/MD.0000000000035951","article-title":"Relationship between thyroid function and dietary inflammatory index in Hashimoto thyroiditis patients","volume":"102","author":"Chen","year":"2023","journal-title":"Medicine"},{"key":"ref_35","first-page":"345","article-title":"Body composition and Hashimoto disease. Rocz","volume":"72","author":"Malczyk","year":"2021","journal-title":"Panstw. Zakl. Hig."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Mikulska-Sauermann, A.A., Resztak, M., Kara\u017aniewicz-\u0141ada, M., Filipowicz, D., Rucha\u0142a, M., and G\u0142\u00f3wka, F.K. (2024). Assessment of Vitamin Concentrations in Patients with Hashimoto\u2019s Thyroiditis and Their Relationships with Thyroid Function, Biochemical Status, and Anthropometric Parameters\u2014A Preliminary Study. Nutrients, 16.","DOI":"10.3390\/nu16111694"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Zhang, L., Yang, L., Luo, Z., Wu, Z., Wang, J., Qin, S., Ren, F., and Hu, T. (2024). Inverse association between serum iron levels and Hashimoto\u2019s thyroiditis in United States females of reproductive age: Analysis of the NHANES 2007\u20132012. Front. Nutr., 11.","DOI":"10.3389\/fnut.2024.1410538"},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Alijani, S., Ghadir, M., and Gargari, B.P. (2024). The association between dietary inflammatory index and dietary total antioxidant capacity and Hashimoto\u2019s thyroiditis: A case-control study. BMC Endocr. Disord., 24.","DOI":"10.1186\/s12902-024-01708-z"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1530\/EC-18-0272","article-title":"The effect of obesity and dietary habits on oxidative stress in Hashimoto\u2019s thyroiditis","volume":"7","author":"Giannakou","year":"2018","journal-title":"Endocr. Connect."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Klobu\u010dar, S., Ken\u0111el Jovanovi\u0107, G., Kryczyk-Kozio\u0142, J., Cigrovski Berkovi\u0107, M., Vu\u010dak Lon\u010dar, J., Mori\u0107, N., Peljhan, K., Raheli\u0107, D., Mudri, D., and Bili\u0107-\u0106ur\u010di\u0107, I. (2024). Association of Dietary Inflammatory Index and Thyroid Function in Patients with Hashimoto\u2019s Thyroiditis: An Observational Cross\u2013Sectional Multicenter Study. Medicina, 60.","DOI":"10.3390\/medicina60091454"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Kali\u010danin, D., Cvek, M., Bari\u0107, A., \u0160krabi\u0107, V., Punda, A., and Boraska Perica, V. (2023). Associations between vitamin D levels and dietary patterns in patients with Hashimoto\u2019s thyroiditis. Front. Nutr., 10.","DOI":"10.3389\/fnut.2023.1188612"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1089\/thy.2020.0299","article-title":"Influence of Dietary Habits on Oxidative Stress Markers in Hashimoto\u2019s Thyroiditis","volume":"31","author":"Ruggeri","year":"2021","journal-title":"Thyroid"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Kali\u010danin, D., Br\u010di\u0107, L., Ljubeti\u0107, K., Bari\u0107, A., Gra\u010dan, S., Brekalo, M., Torlak Lovri\u0107, V., Kol\u010di\u0107, I., Pola\u0161ek, O., and Zemunik, T. (2020). Differences in food consumption between patients with Hashimoto\u2019s thyroiditis and healthy individuals. Sci. Rep., 10.","DOI":"10.1038\/s41598-020-67719-7"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Li, J., Huang, Q., Sun, S., Zhou, K., Wang, X., Pan, K., Zhang, Y., Wang, Y., Han, Q., and Si, C. (2024). Thyroid antibodies in Hashimoto\u2019s thyroiditis patients are positively associated with inflammation and multiple symptoms. Sci. Rep., 14.","DOI":"10.1038\/s41598-024-78938-7"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Adamska, A., Pop\u0142awska-Kita, A., Siewko, K., \u0141ebkowska, A., Krentowska, A., Buczy\u0144ska, A., Pop\u0142awski, \u0141., Szumowski, P., Szelachowska, M., and Kr\u0119towski, A.J. (2021). Body Composition and Serum Anti-M\u00fcllerian Hormone Levels in Euthyroid Caucasian Women With Hashimoto Thyroiditis. Front. Endocrinol., 12.","DOI":"10.3389\/fendo.2021.657752"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1007\/s12020-015-0624-8","article-title":"Evaluation of hearing functions in patients with euthyroid Hashimoto\u2019s thyroiditis","volume":"50","author":"Arduc","year":"2015","journal-title":"Endocrine"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1080\/08820139.2018.1529040","article-title":"Thyroglobulin Antibodies are Associated with Symptom Burden in Patients with Hashimoto\u2019s Thyroiditis: A Cross-Sectional Study","volume":"48","author":"Brekalo","year":"2019","journal-title":"Immunol. Invest."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Cvek, M., Kali\u010danin, D., Bari\u0107, A., Vuleti\u0107, M., Gunja\u010da, I., Torlak Lovri\u0107, V., \u0160krabi\u0107, V., Punda, A., and Boraska Perica, V. (2021). Vitamin D and Hashimoto\u2019s Thyroiditis: Observations from CROHT Biobank. Nutrients, 13.","DOI":"10.3390\/nu13082793"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1080\/1028415X.2022.2110188","article-title":"The association of ultra-processed food consumption with adult mental health disorders: A systematic review and dose-response meta-analysis of 260,385 participants","volume":"26","author":"Mazloomi","year":"2023","journal-title":"Nutr. Neurosci."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"101403","DOI":"10.1016\/j.arr.2021.101403","article-title":"Associations between nutrition and the incidence of depression in middle-aged and older adults: A systematic review and meta-analysis of prospective observational population-based studies","volume":"70","author":"Matison","year":"2021","journal-title":"Ageing Res. Rev."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1017\/S0033291719001958","article-title":"Association of a priori dietary patterns with depressive symptoms: A harmonised meta-analysis of observational studies","volume":"50","author":"Nicolaou","year":"2020","journal-title":"Psychol. Med."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s41043-022-00303-z","article-title":"Dietary inflammatory potential and the incidence of depression and anxiety: A meta-analysis","volume":"41","author":"Li","year":"2022","journal-title":"J. Health Popul. Nutr."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Zhang, H., Li, M., Mo, L., Luo, J., Shen, Q., and Quan, W. (2023). Association between Western Dietary Patterns, Typical Food Groups, and Behavioral Health Disorders: An Updated Systematic Review and Meta-Analysis of Observational Studies. Nutrients, 16.","DOI":"10.3390\/nu16010125"},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Deligiannidou, G.-E., Philippou, E., Vasiari, E., de Andrade, V.L., Massaro, M., Chervenkov, M., Ivanova, T., Jorge, R., Dimitrova, D., and Ruskovska, T. (2024). Exploring the Relationship between Mediterranean Diet Adherence and Subjective Well-Being among Greek and Cypriot Adults. Nutrients, 16.","DOI":"10.3390\/nu16081238"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1093\/pm\/pnaa378","article-title":"Dietary Interventions Are Beneficial for Patients with Chronic Pain: A Systematic Review with Meta-Analysis","volume":"22","author":"Field","year":"2021","journal-title":"Pain Med."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3945\/an.114.007617","article-title":"Dietary Patterns, Cognitive Decline, and Dementia: A Systematic Review","volume":"6","author":"Berendsen","year":"2015","journal-title":"Adv. Nutr."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"101936","DOI":"10.1016\/j.smrv.2024.101936","article-title":"Dietary patterns and insomnia symptoms: A systematic review and meta-analysis","volume":"75","author":"Arab","year":"2024","journal-title":"Sleep Med. Rev."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Fabiani, R., Naldini, G., and Chiavarini, M. (2019). Dietary Patterns and Metabolic Syndrome in Adult Subjects: A Systematic Review and Meta-Analysis. Nutrients, 11.","DOI":"10.3390\/nu11092056"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1001\/jama.2018.13770","article-title":"Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis","volume":"320","author":"Feller","year":"2018","journal-title":"JAMA"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1210\/jc.2017-02668","article-title":"Effects of Altering Levothyroxine (L-T4) Doses on Quality of Life, Mood, and Cognition in L-T4 Treated Subjects","volume":"103","author":"Samuels","year":"2018","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.ijsu.2015.08.001","article-title":"Quality of life improvement in patients with Hashimoto thyroiditis and other goiters after surgery: A prospective cohort study","volume":"21","author":"Zivaljevic","year":"2015","journal-title":"Int. J. Surg."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.amsu.2020.10.030","article-title":"Quality of life among patients on levothyroxine: A cross-sectional study","volume":"60","author":"Bataineh","year":"2020","journal-title":"Ann. Med. Surg."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1001\/jamapsychiatry.2018.0190","article-title":"Association of Depression and Anxiety Disorders With Autoimmune Thyroiditis","volume":"75","author":"Siegmann","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Ma, Y., Wang, M., and Zhang, Z. (2024). The association between depression and thyroid function. Front. Endocrinol., 15.","DOI":"10.3389\/fendo.2024.1454744"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1507\/endocrj.EJ16-0418","article-title":"Is thyroid autoimmunity itself associated with psychological well-being in euthyroid Hashimoto\u2019s thyroiditis?","volume":"64","author":"Yalcin","year":"2017","journal-title":"Endocr. J."},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Yuan, J., Qi, S., Zhang, X., Lai, H., Li, X., Xiaoheng, C., Li, Z., Yao, S., and Ding, Z. (2023). Local symptoms of Hashimoto\u2019s thyroiditis: A systematic review. Front. Endocrinol., 13.","DOI":"10.3389\/fendo.2022.1076793"},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Yue, C., Gu, L., and Guo, W. (2024). Likelihood of Laryngeal Involvement in Autoimmune Thyroid Disorder Patients: A Meta-Analysis. Endocr. Metab. Immune Disord. Drug Targets, ahead of print.","DOI":"10.2174\/0118715303304858240904042316"},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Xu, G.-M., Hu, M.-X., Li, S.-Y., Ran, X., Zhang, H., and Ding, X.-F. (2024). Thyroid disorders and gastrointestinal dysmotility: An old association. Front. Physiol., 15.","DOI":"10.3389\/fphys.2024.1389113"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s12020-019-02185-4","article-title":"Prevalence of gastrointestinal disorders having an impact on tablet levothyroxine absorption: Should this formulation still be considered as the first-line therapy?","volume":"67","author":"Castellana","year":"2020","journal-title":"Endocrine"},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Zeng, W., Wang, Y., and Zhang, L. (2024). Associations of thyroid hormones with chronic diarrhea and constipation in euthyroid individuals. Front. Endocrinol., 15.","DOI":"10.3389\/fendo.2024.1395743"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1002\/fsn3.3270","article-title":"Cross-sectional associations between healthy eating index and thyroid function in U.S. male Adults, NHANES 2007\u20132012","volume":"11","author":"Chen","year":"2023","journal-title":"Food Sci. Nutr."},{"key":"ref_72","first-page":"253","article-title":"Iron and ferritin deficiency in women with hypothyroidism and chronic lymphocytic thyroiditis\u2014systematic review","volume":"75","author":"Gierach","year":"2024","journal-title":"Endokrynol. Polska"},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Soda, M., Priante, C., Pesce, C., De Maio, G., and Lombardo, M. (2024). The Impact of Vitamin D on Immune Function and Its Role in Hashimoto\u2019s Thyroiditis: A Narrative Review. Life, 14.","DOI":"10.3390\/life14060771"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1089\/thy.2023.0556","article-title":"Selenium Supplementation in Patients with Hashimoto Thyroiditis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials","volume":"34","author":"Huwiler","year":"2024","journal-title":"Thyroid"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/jcpt.13605","article-title":"Effects of vitamin D treatment on thyroid function and autoimmunity markers in patients with Hashimoto\u2019s thyroiditis\u2014A meta-analysis of randomized controlled trials","volume":"47","author":"Jiang","year":"2022","journal-title":"J. Clin. Pharm. Ther."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"e33791","DOI":"10.1097\/MD.0000000000033791","article-title":"Clinical efficacy of selenium supplementation in patients with Hashimoto thyroiditis: A systematic review and meta-analysis","volume":"102","author":"Kong","year":"2023","journal-title":"Medicine"},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Kravchenko, V., and Zakharchenko, T. (2023). Thyroid hormones and minerals in immunocorrection of disorders in autoimmune thyroid diseases. Front. Endocrinol., 14.","DOI":"10.3389\/fendo.2023.1225494"},{"key":"ref_78","doi-asserted-by":"crossref","unstructured":"Mikulska, A.A., Kara\u017aniewicz-\u0141ada, M., Filipowicz, D., Rucha\u0142a, M., and G\u0142\u00f3wka, F.K. (2022). Metabolic Characteristics of Hashimoto\u2019s Thyroiditis Patients and the Role of Microelements and Diet in the Disease Management\u2014An Overview. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23126580"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"e36759","DOI":"10.1097\/MD.0000000000036759","article-title":"Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto\u2019s thyroiditis: A systematic review and meta-analysis","volume":"102","author":"Tang","year":"2023","journal-title":"Medicine"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"030006052110606","DOI":"10.1177\/03000605211060675","article-title":"Effects of vitamin D on thyroid autoimmunity markers in Hashimoto\u2019s thyroiditis: Systematic review and meta-analysis","volume":"49","author":"Zhang","year":"2021","journal-title":"J. Int. Med. Res."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"86","DOI":"10.2174\/1871530322666220627145635","article-title":"Correlation Between Vitamin B12 Deficiency and Autoimmune Thyroid Diseases","volume":"23","author":"Kacharava","year":"2023","journal-title":"Endocr. Metab. Immune Disord. Drug Targets"},{"key":"ref_82","doi-asserted-by":"crossref","unstructured":"Wang, K., Wei, H., Zhang, W., Li, Z., Ding, L., Yu, T., Tan, L., Liu, Y., Liu, T., and Wang, H. (2018). Severely low serum magnesium is associated with increased risks of positive anti-thyroglobulin antibody and hypothyroidism: A cross-sectional study. Sci. Rep., 8.","DOI":"10.1038\/s41598-018-28362-5"},{"key":"ref_83","first-page":"367","article-title":"Immunological harmony: The role of magnesium in the development of euthyroid Hashimoto\u2019s thyroiditis","volume":"29","author":"Celik","year":"2024","journal-title":"J. Elem."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1159\/000505094","article-title":"Vitamin B12 and Vitamin D Levels in Patients with Autoimmune Hypothyroidism and Their Correlation with Anti-Thyroid Peroxidase Antibodies","volume":"29","author":"Aktas","year":"2020","journal-title":"Med. Princ. 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