{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:48:41Z","timestamp":1790660921819,"version":"4.1.0"},"reference-count":30,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: Sarcopenia, defined by a loss of muscle mass, strength, and function, is a potential comorbidity in axial spondyloarthritis (axSpA). Its prevalence, along with malnutrition, remains unclear. Methods: This cross-sectional study assessed sarcopenia (using the European Working Group on Sarcopenia in Older People (EWGSOP-2) criteria), presarcopenia, and malnutrition (using the Global Leadership Initiative on Malnutrition (GLIM) criteria) in a Spanish axSpA cohort. We included 94 patients aged \u2265 50 years. Sarcopenia was evaluated using the SARC-F questionnaire and by measuring muscle strength, mass, and performance. Presarcopenia was defined as low muscle mass alone. Malnutrition was assessed using body mass index (BMI) and fat-free mass index (FFMI). Results: The prevalence of sarcopenia, presarcopenia, and malnutrition was 3.2%, 23.4%, and 10.6%, respectively. Sarcopenia correlated with worse functionality and quality of life (Bath Ankylosing Spondylitis Functional Index (BASFI) 7.6 \u00b1 1.2 vs. 3.6 \u00b1 2.5, p = 0.02; ASAS Health Index (ASAS-HI) 11 \u00b1 2 vs. 5.6 \u00b1 3.7, p = 0.03). Presarcopenia was linked to a lower BMI (24.7 \u00b1 4.1 vs. 29.1 \u00b1 4.2, p &lt; 0.01), FFMI (16.1 \u00b1 2 vs. 19.6 \u00b1 2.6, p &lt; 0.01), and reduced biologic treatment use (31.8% vs. 61.1%, p = 0.03). Malnourished patients had lower muscle mass (5.14 \u00b1 0.73 vs. 6.23 \u00b1 0.96, p &lt; 0.01). SARC-F showed 100% sensitivity and 75.8% specificity for sarcopenia detection. Conclusions: Despite low sarcopenia prevalence, presarcopenia and malnutrition are frequent, highlighting the need for early detection in axSpA.<\/jats:p>","DOI":"10.3390\/nu17061019","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T07:02:16Z","timestamp":1741935736000},"page":"1019","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessing Sarcopenia, Presarcopenia, and Malnutrition in Axial Spondyloarthritis: Insights from a Spanish Cohort"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3373-7503","authenticated-orcid":false,"given":"Laura","family":"Berbel-Arcob\u00e9","sequence":"first","affiliation":[{"name":"Rheumatology Department, Hospital Universitari de Bellvitge-IDIBELL, Carrer de la Feixa Llarga S\/N, L\u2019Hospitalet de Llobregat, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9119-5330","authenticated-orcid":false,"given":"Diego","family":"Benavent","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital Universitari de Bellvitge-IDIBELL, Carrer de la Feixa Llarga S\/N, L\u2019Hospitalet de Llobregat, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Valencia-Muntal\u00e0","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital Universitari de Bellvitge-IDIBELL, Carrer de la Feixa Llarga S\/N, L\u2019Hospitalet de Llobregat, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"G\u00f3mez-Vaquero","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital Universitari de Bellvitge-IDIBELL, Carrer de la Feixa Llarga S\/N, L\u2019Hospitalet de Llobregat, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Juanola","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital Universitari de Bellvitge-IDIBELL, Carrer de la Feixa Llarga S\/N, L\u2019Hospitalet de Llobregat, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2358-6767","authenticated-orcid":false,"given":"Joan M.","family":"Nolla","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital Universitari de Bellvitge-IDIBELL, Carrer de la Feixa Llarga S\/N, L\u2019Hospitalet de Llobregat, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1136\/ard.2004.029728","article-title":"Association between radiographic damage of the spine and spinal mobility for individual patients with ankylosing spondylitis: Can assessment of spinal mobility be a proxy for radiographic evaluation?","volume":"64","author":"Wanders","year":"2005","journal-title":"Ann. 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