{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:39:24Z","timestamp":1792028364380,"version":"4.4.0"},"reference-count":51,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fondazione Cassa di Risparmio di Torino","award":["2022.AI1398.U1598"],"award-info":[{"award-number":["2022.AI1398.U1598"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Anorexia nervosa (AN) remains a severe psychiatric disorder with multifactorial pathogenesis and an uncertain prognosis. It is essential to identify any factors that may contribute to its onset in order to improve the targeting of preventive and therapeutic interventions. The present study explores the characteristics of parents of daughters with AN, comparing those with different ages of onset and ages at intake, in order to identify potential contributing factors from the parental side. Methods: The study recruited 69 adolescents and 56 adults diagnosed with AN, along with 73 healthy controls (HC). The 80 mothers and 69 fathers of the participants were compared to controls in terms of the age of onset and age at intake of their daughters. Self-administered instruments were used to assess personality (TCI), eating behaviors (EDI-2), general psychopathology (BDI), and family functioning (FAD). Results: The analysis revealed that several personality and psychopathological traits distinguished the parents of AN participants from the HC group in both conditions. Both mothers of adolescent- and adult-onset AN participants with any age at intake displayed greater harm avoidance and lower self-directedness facets, as well as greater inadequacy and social insecurity than controls. Fathers were less disordered and more self-indulgent and compassionate, but lower in role definition. Specifically, mothers of daughters with adolescent-onset AN and younger age at intake were more prone to depression. In contrast, mothers of daughters with an adult age at intake showed lower resourcefulness and higher levels of perceived inadequacy. Conclusions: Higher resourcefulness and a lower sense of ineffectiveness may help mothers facilitate earlier therapeutic intervention for their daughters. On the other hand, maternal depressive symptoms may play a significant role in the earlier onset of and intake for AN in their daughters. Supporting assertive qualities in mothers through preventive interventions is recommended, while maternal depression should be appropriately treated to prevent an early psychopathological onset in daughters.<\/jats:p>","DOI":"10.3390\/nu17071115","type":"journal-article","created":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T04:48:18Z","timestamp":1742791698000},"page":"1115","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Parents of Adolescents with Anorexia Nervosa and Parents of Adult Women with Anorexia Nervosa"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7079-8391","authenticated-orcid":false,"given":"Federico","family":"Amianto","sequence":"first","affiliation":[{"name":"Neurosciences Department, University of Torino, Via Cherasco 15, 10126 Torino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Dell\u2019Oca","sequence":"additional","affiliation":[{"name":"Neurosciences Department, University of Torino, Via Cherasco 15, 10126 Torino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Marcotulli","sequence":"additional","affiliation":[{"name":"Section of Child and Adolescent Neuropsychiatry, Department of Public Health and Pediatric Sciences, University of Turin, 10126 Torino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4378-8419","authenticated-orcid":false,"given":"Chiara","family":"Davico","sequence":"additional","affiliation":[{"name":"Section of Child and Adolescent Neuropsychiatry, Department of Public Health and Pediatric Sciences, University of Turin, 10126 Torino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0319-3579","authenticated-orcid":false,"given":"Andrea","family":"Martinuzzi","sequence":"additional","affiliation":[{"name":"Section of Child and Adolescent Neuropsychiatry, Department of Public Health and Pediatric Sciences, University of Turin, 10126 Torino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/eat.22005","article-title":"The need for complex ideas in anorexia nervosa: Why biology, environment, and psyche all matter, why therapists make mistakes, and why clinical benchmarks are needed for managing weight correction","volume":"45","author":"Strober","year":"2012","journal-title":"Int. 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