{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T13:13:42Z","timestamp":1791724422198,"version":"4.3.4"},"reference-count":178,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T00:00:00Z","timestamp":1743292800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Exxon Mobil-NUS Research Fellowship grant","award":["exxonmobil2023"],"award-info":[{"award-number":["exxonmobil2023"]}]},{"name":"Exxon Mobil-NUS Research Fellowship grant","award":["CNIG23jul-0001"],"award-info":[{"award-number":["CNIG23jul-0001"]}]},{"name":"National Medical Research Council New Investigator grant","award":["exxonmobil2023"],"award-info":[{"award-number":["exxonmobil2023"]}]},{"name":"National Medical Research Council New Investigator grant","award":["CNIG23jul-0001"],"award-info":[{"award-number":["CNIG23jul-0001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Gestational diabetes mellitus (GDM) is a complication that affects 20% of pregnancies worldwide. It is associated with adverse short- and long-term cardiometabolic outcomes for both mother and infant. Effective management of GDM involves lifestyle modifications, including medical nutrition therapy (MNT) and physical activity (PA), with the addition of insulin or metformin if glycaemic control remains inadequate. However, substantial gaps persist in the determination of optimal medical nutrition therapy (MNT) for women with GDM. Challenges in MNT include individual variation in glucose tolerance and changing maternal physiology and dietary requirements during pregnancy. Achieving optimal glycaemic control depends on careful macronutrient balance, particularly the distribution and quality of carbohydrate intake and sufficient protein and fat intake. Additionally, micronutrient deficiencies, such as inadequate vitamin D, calcium, and essential minerals, may exacerbate oxidative stress, inflammation, and glycaemic dysregulation, further impacting foetal growth and development. Cultural beliefs and dietary practices among pregnant women can also hinder adherence to recommended nutritional guidelines. Conditions like hyperemesis gravidarum (HG) affect ~1% to 2% of pregnant women can result in unintended energy and nutrient deficits. This special issue explores the current evidence and major barriers to optimising dietary therapy for women with GDM. It also identifies future research priorities to advance clinical practice, improve maternal and foetal outcomes, and address gaps in personalised nutrition interventions.<\/jats:p>","DOI":"10.3390\/nu17071210","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T01:59:36Z","timestamp":1743386376000},"page":"1210","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Medical Nutrition Therapy for Women with Gestational Diabetes: Current Practice and Future Perspectives"],"prefix":"10.3390","volume":"17","author":[{"given":"Louisa","family":"Cheong","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, National University Hospital, Singapore 119074, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0429-2632","authenticated-orcid":false,"given":"Lawrence Siu-Chun","family":"Law","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, National University Hospital, Singapore 119074, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Ying Lyeann","family":"Tan","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, National University Hospital, Singapore 119074, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal Al-Amri","family":"Amal","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nizwa Hospital, Nizwa P.O. Box 1222, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin Meng","family":"Khoo","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, National University Hospital, Singapore 119074, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4172-1344","authenticated-orcid":false,"given":"Pei Chia","family":"Eng","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, National University Hospital, Singapore 119074, Singapore"},{"name":"Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S154","DOI":"10.2337\/diabetes.50.2007.S154","article-title":"Beta-cell adaptation and decompensation during the progression of diabetes","volume":"50","author":"Weir","year":"2001","journal-title":"Diabetes"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.mce.2008.08.012","article-title":"The incretin system and its role in type 2 diabetes mellitus","volume":"297","author":"Holst","year":"2009","journal-title":"Mol. 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