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Methods: We examined the impact of the Mediterranean Diet and Ultra Processed Food (UPF) intake on the risk of prevalent MASLD in older adults. Results: Our major findings include that increased adherence to a Mediterranean Dietary pattern was associated with a decreased risk of MASLD. Additionally, we found that high UPF intake was associated with an increased risk of MASLD. Furthermore, our study found that even with a high UPF intake, the risk of MASLD decreased if the individual also had a higher Mediterranean Diet intake compared to a lower Mediterranean Diet intake. Conclusions: These results are of particular importance in older people, given the known links between MASLD, metabolic comorbidities and frailty. Public health messaging should focus on promoting Mediterranean dietary habits, and ways to help older people achieve this given the social and economic barriers they may face.<\/jats:p>","DOI":"10.3390\/nu17091415","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T06:38:37Z","timestamp":1745390317000},"page":"1415","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Associations Between MASLD, Ultra-Processed Food and a Mediterranean Dietary Pattern in Older Adults"],"prefix":"10.3390","volume":"17","author":[{"given":"Isabella","family":"Commins","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia"},{"name":"School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7479-9669","authenticated-orcid":false,"given":"Daniel","family":"Clayton-Chubb","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia"},{"name":"School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia"},{"name":"Department of Gastroenterology, Eastern Health, Box Hill, VIC 3128, Australia"},{"name":"Department of Gastroenterology, St Vincent\u2019s Hospital Melbourne, Fitzroy, VIC 3065, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica A.","family":"Fitzpatrick","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia"},{"name":"School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1385-2371","authenticated-orcid":false,"given":"Elena S.","family":"George","sequence":"additional","affiliation":[{"name":"Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3220, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans G.","family":"Schneider","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia"},{"name":"Department of Pathology, Alfred Health, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aung Zaw Zaw","family":"Phyo","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ammar","family":"Majeed","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia"},{"name":"School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5693-0248","authenticated-orcid":false,"given":"Natasha","family":"Janko","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia"},{"name":"School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Vaughan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia"},{"name":"Department of Nutrition & Dietetics, Alfred Health, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1249-6149","authenticated-orcid":false,"given":"Robyn L.","family":"Woods","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4807-6069","authenticated-orcid":false,"given":"Alice J.","family":"Owen","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1049-5129","authenticated-orcid":false,"given":"John J.","family":"McNeil","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0787-7273","authenticated-orcid":false,"given":"William W.","family":"Kemp","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia"},{"name":"School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9015-7997","authenticated-orcid":false,"given":"Stuart K.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia"},{"name":"School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,23]]},"reference":[{"key":"ref_1","first-page":"S32","article-title":"Epidemiology of 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