{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:25:45Z","timestamp":1760059545401,"version":"build-2065373602"},"reference-count":33,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Andalusian Society of Nutrition and Dietetics (SANCYD)","award":["8-2024","B35982818"],"award-info":[{"award-number":["8-2024","B35982818"]}]},{"name":"Lima Farma","award":["8-2024","B35982818"],"award-info":[{"award-number":["8-2024","B35982818"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Objectives: To describe the results of nutritional and morphofunctional assessment in a cohort of adults with cystic fibrosis; to evaluate differences in nutritional status between patients with and without exocrine and\/or endocrine pancreatic involvement. Methods: Cross-sectional study: A cohort of adults with cystic fibrosis evaluated in a multidisciplinary unit was analyzed. Pancreatic status was examined, and malnutrition was diagnosed according to GLIM criteria. Morphofunctional assessment consisted of nutritional ultrasound, bioelectrical impedance, handgrip dynamometry, and anthropometry. Qualitative variables are expressed as n (%), quantitative variables as median (IQR). For group comparisons, Fisher\u2019s exact test was used for qualitative variables and the non-parametric median comparison test for quantitative variables. Results: n = 101 participants were recruited, of whom 44 (43.6%) were women. Median age was 33 (25\u201340.5) years. A total of 64 participants (63.4%) had exocrine pancreatic insufficiency (EPI), 44 (43.6%) had endocrine pancreatic insufficiency, and 28 (27.7%) had cystic fibrosis-related diabetes (CFRD). Median BMI was 23.4 (20.1\u201324.89) kg\/m2. A total of 48 patients (47.5%) were malnourished. Males with EPI had a higher prevalence of undernourishment than those without (56.4% vs. 16.7%, p = 0.005), but not women. CFRD patients displayed no differences in morphofunctional assessment. Conclusions: Almost half the sample was undernourished using GLIM criteria. Males with exocrine pancreatic insufficiency had worse nutritional status. Endocrine pancreatic involvement did not affect nutritional status.<\/jats:p>","DOI":"10.3390\/nu17132057","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T11:23:24Z","timestamp":1750418604000},"page":"2057","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nutritional and Morphofunctional Assessment in a Cohort of Adults Living with Cystic Fibrosis with or Without Pancreatic Exocrine and\/or Endocrine Involvement"],"prefix":"10.3390","volume":"17","author":[{"given":"Ana","family":"Pi\u00f1ar-Guti\u00e9rrez","sequence":"first","affiliation":[{"name":"UGC Endocrinolog\u00eda y Nutrici\u00f3n, Hospital Universitario Virgen del Roc\u00edo, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Pereira-Cunill","sequence":"additional","affiliation":[{"name":"UGC Endocrinolog\u00eda y Nutrici\u00f3n, Instituto de Biomedicina de Sevilla, IBiS\/Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6130-8184","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Jim\u00e9nez-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"UGC Endocrinolog\u00eda y Nutrici\u00f3n, Instituto de Biomedicina de Sevilla, IBiS\/Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5192-8026","authenticated-orcid":false,"given":"Silvia","family":"Garc\u00eda-Rey","sequence":"additional","affiliation":[{"name":"UGC Endocrinolog\u00eda y Nutrici\u00f3n, Hospital Universitario Virgen del Roc\u00edo, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Roque-Cu\u00e9llar","sequence":"additional","affiliation":[{"name":"UGC Endocrinolog\u00eda y Nutrici\u00f3n, Hospital Universitario Virgen del Roc\u00edo, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2878-4017","authenticated-orcid":false,"given":"Antonio","family":"Mart\u00ednez-Ortega","sequence":"additional","affiliation":[{"name":"UGC Endocrinolog\u00eda y Nutrici\u00f3n, Instituto de Biomedicina de Sevilla, IBiS\/Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Gonz\u00e1lez-Navarro","sequence":"additional","affiliation":[{"name":"UGC Endocrinolog\u00eda y Nutrici\u00f3n, Hospital Universitario Virgen del Roc\u00edo, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2747-1921","authenticated-orcid":false,"given":"Esther","family":"Quintana-Gallego","sequence":"additional","affiliation":[{"name":"UGC Neumolog\u00eda y Cirug\u00eda Tor\u00e1cica, Instituto de Biomedicina de Sevilla, IBiS\/Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ngeles","family":"Pizarro","sequence":"additional","affiliation":[{"name":"UGC Aparato Digestivo, Instituto de Biomedicina de Sevilla, IBiS\/Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Castell","sequence":"additional","affiliation":[{"name":"UGC Radiodiagn\u00f3stico, Instituto de Biomedicina de Sevilla, IBiS\/Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Romero-G\u00f3mez","sequence":"additional","affiliation":[{"name":"UGC Aparato Digestivo, Instituto de Biomedicina de Sevilla, IBiS\/Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7460-5422","authenticated-orcid":false,"given":"Pedro","family":"Garc\u00eda-Luna","sequence":"additional","affiliation":[{"name":"UGC Endocrinolog\u00eda y Nutrici\u00f3n, Instituto de Biomedicina de Sevilla, IBiS\/Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla, Avda. Manuel Siurot s\/n, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1056\/NEJMra2216474","article-title":"Cystic Fibrosis","volume":"389","author":"Grasemann","year":"2023","journal-title":"N. Engl. J. 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