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(BMBF)","award":["P06-CTS-02341"],"award-info":[{"award-number":["P06-CTS-02341"]}],"id":[{"id":"https:\/\/ror.org\/04pz7b180","id-type":"ROR","asserted-by":"crossref"}]},{"name":"German Federal Ministry of Education and Research (BMBF)","award":["BFU2012-40254-C03-01"],"award-info":[{"award-number":["BFU2012-40254-C03-01"]}],"id":[{"id":"https:\/\/ror.org\/04pz7b180","id-type":"ROR","asserted-by":"crossref"}]},{"name":"German Federal Ministry of Education and Research (BMBF)","award":["ERC-2012-AdG e no. 322605"],"award-info":[{"award-number":["ERC-2012-AdG e no. 322605"]}],"id":[{"id":"https:\/\/ror.org\/04pz7b180","id-type":"ROR","asserted-by":"crossref"}]},{"name":"German Federal Ministry of Education and Research (BMBF)","award":["01GL2406A"],"award-info":[{"award-number":["01GL2406A"]}],"id":[{"id":"https:\/\/ror.org\/04pz7b180","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Else Kr\u00f6ner-Fresenius-Foundation and the Medical Faculty of LMU Munich","award":["P06-CTS-02341"],"award-info":[{"award-number":["P06-CTS-02341"]}],"id":[{"id":"https:\/\/ror.org\/05591te55","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Else Kr\u00f6ner-Fresenius-Foundation and the Medical Faculty of LMU Munich","award":["BFU2012-40254-C03-01"],"award-info":[{"award-number":["BFU2012-40254-C03-01"]}],"id":[{"id":"https:\/\/ror.org\/05591te55","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Else Kr\u00f6ner-Fresenius-Foundation and the Medical Faculty of LMU Munich","award":["ERC-2012-AdG e no. 322605"],"award-info":[{"award-number":["ERC-2012-AdG e no. 322605"]}],"id":[{"id":"https:\/\/ror.org\/05591te55","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Else Kr\u00f6ner-Fresenius-Foundation and the Medical Faculty of LMU Munich","award":["01GL2406A"],"award-info":[{"award-number":["01GL2406A"]}],"id":[{"id":"https:\/\/ror.org\/05591te55","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Fatty acid status during the perinatal period is important for optimal offspring growth and development. Objectives: We aimed to test the association between maternal fatty acid (FA) intake during the third trimester of pregnancy and the FA composition of placental phospholipids, a marker of maternal fatty acid status. Methods: This cohort study was performed on 54 mothers participating in the PREOBE study. Maternal dietary intake was assessed with prospective 7-day food diaries at 34 weeks of gestation. Placenta samples were collected immediately after delivery and phospholipid FA was quantified with established methods. Data were analyzed with Pearson correlations and linear regression models, with adjustment for confounding factors. Results: Total energy intake was 2019 \u00b1 527 kcal\/d (mean \u00b1 SD) and total fat intake of the mothers was 87 \u00b1 35 g\/day. Myristic, stearic, oleic, and \u03b1-linolenic acid intakes were modestly correlated with placental percentages, with r-values \u2264 0.33. Only docosahexaenoic (DHA) acid intake (%-energy, %-fat, and g\/d) showed r-values &gt; 0.4 for the correlation with placenta phospholipids. Intake of other fatty acids, including arachidonic acid, was not associated with the placenta percentage. Linear regression models considering confounders showed only dietary DHA intake significant associations. Total fat intake did not interfere with the association of DHA intake with placental incorporation. Conclusions: DHA and arachidonic acid are enriched in the placenta, but only placental DHA content seems modifiable by maternal dietary DHA intake.<\/jats:p>","DOI":"10.3390\/nu17152394","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T15:00:42Z","timestamp":1753196442000},"page":"2394","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Association Between Maternal Dietary Fatty Acid Intake and Fatty Acid Composition of Placental Phospholipids"],"prefix":"10.3390","volume":"17","author":[{"given":"Liliana","family":"Ladino","sequence":"first","affiliation":[{"name":"Department Pediatrics, Dr. von Hauner Children\u2019s Hospital, Division of Metabolic and Nutritional Medicine, LMU University Hospitals, LMU\u2014Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, 80337 Munich, Germany"},{"name":"German Center for Child and Adolescent Health, 81377 Munich, Germany"},{"name":"Excellence Centre for Paediatric Research (EURISTIKOS), University of Granada, 18016 Granada, Spain"},{"name":"Research and Education Center on Nutrition, CIENutrition, Bogot\u00e1 110221, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7812-5178","authenticated-orcid":false,"given":"Hans","family":"Demmelmair","sequence":"additional","affiliation":[{"name":"Department Pediatrics, Dr. von Hauner Children\u2019s Hospital, Division of Metabolic and Nutritional Medicine, LMU University Hospitals, LMU\u2014Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, 80337 Munich, Germany"},{"name":"German Center for Child and Adolescent Health, 81377 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Teresa","family":"Segura","sequence":"additional","affiliation":[{"name":"Excellence Centre for Paediatric Research (EURISTIKOS), University of Granada, 18016 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mireia","family":"Escudero-Marin","sequence":"additional","affiliation":[{"name":"Excellence Centre for Paediatric Research (EURISTIKOS), University of Granada, 18016 Granada, Spain"},{"name":"Department of Paediatrics, University of Granada, 18016 Granada, Spain"},{"name":"Biosanitary Research Institute of Granada (Ibs-GRANADA), 18014 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7168-2385","authenticated-orcid":false,"given":"Veit","family":"Grote","sequence":"additional","affiliation":[{"name":"Department Pediatrics, Dr. von Hauner Children\u2019s Hospital, Division of Metabolic and Nutritional Medicine, LMU University Hospitals, LMU\u2014Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, 80337 Munich, Germany"},{"name":"German Center for Child and Adolescent Health, 81377 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berthold","family":"Koletzko","sequence":"additional","affiliation":[{"name":"Department Pediatrics, Dr. von Hauner Children\u2019s Hospital, Division of Metabolic and Nutritional Medicine, LMU University Hospitals, LMU\u2014Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, 80337 Munich, Germany"},{"name":"German Center for Child and Adolescent Health, 81377 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9860-6785","authenticated-orcid":false,"given":"Cristina","family":"Campoy","sequence":"additional","affiliation":[{"name":"Excellence Centre for Paediatric Research (EURISTIKOS), University of Granada, 18016 Granada, Spain"},{"name":"Department of Paediatrics, University of Granada, 18016 Granada, Spain"},{"name":"Biosanitary Research Institute of Granada (Ibs-GRANADA), 18014 Granada, Spain"},{"name":"CIBERESP\u2014Epidemiology and Public Health Research Network\u2014ISCIII, Granada\u2019s Node, 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,22]]},"reference":[{"key":"ref_1","first-page":"425","article-title":"The developmental origins of health and disease: Current theories and epigenetic mechanisms","volume":"64","author":"Sinclair","year":"2007","journal-title":"Soc. 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