{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T05:22:26Z","timestamp":1774588946633,"version":"3.50.1"},"reference-count":52,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea (NRF)","doi-asserted-by":"publisher","award":["2021R1A2C1007869"],"award-info":[{"award-number":["2021R1A2C1007869"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: This study aimed to investigate the association between dietary patterns and the risk of developing osteoporosis in women, emphasizing the role of nutrition in bone health during menopause-related hormonal changes. Methods: We conducted a prospective study involving 4865 women aged 40\u201369 years without osteoporosis at baseline. Dietary information was collected using a validated semi-quantitative food frequency questionnaire, and composite-defined osteoporosis (CDO) was defined using self-administered questionnaires and quantitative ultrasound. Multivariate Cox proportional hazards regression analysis was employed to calculate hazard ratios and 95% confidence intervals to assess the association between dietary patterns and the risk of CDO. Results: During a median follow-up of 8.26 years, 895 and 1525 cases of CDO were reported in premenopausal and postmenopausal women, respectively. Three dietary patterns were identified in premenopausal women: the \u201cVegetables and Seafood,\u201d \u201cWestern,\u201d and \u201cWhite rice, Meat, and Alcohol\u201d patterns. In postmenopausal women, the \u201cDiverse,\u201d \u201cPlant-based,\u201d and \u201cSweets and Drinks\u201d patterns were identified. Among premenopausal women, the \u201cWhite rice, Meat, and Alcohol\u201d pattern was associated with a significantly greater risk of CDO in the highest tertile compared with that in the lowest tertile, whereas no significant patterns were observed in postmenopausal women. Conclusions: These findings underscore the importance of dietary factors in maintaining bone health, particularly in premenopausal women. Encouraging the reduction in dietary factors associated with an increased osteoporosis risk may help improve bone health and quality of life in women, especially before significant menopause-induced bone loss occurs. This study highlights the need for early dietary interventions to prevent osteoporosis in women.<\/jats:p>","DOI":"10.3390\/nu17182947","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T09:43:41Z","timestamp":1757929421000},"page":"2947","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dietary Patterns and the Risk of Composite-Defined Osteoporosis in Pre- and Postmenopausal Women: A Prospective Cohort Study"],"prefix":"10.3390","volume":"17","author":[{"given":"Yejung","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Food & Nutrition, Yeungnam University, 280 Daehak-ro, Gyeongsan 38541, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4681-1584","authenticated-orcid":false,"given":"Kyong","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Food & Nutrition, Yeungnam University, 280 Daehak-ro, Gyeongsan 38541, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Nih Consensus Development Panel on Osteoporosis Prevention Diagnosis Therapy (2001). 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