{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T13:32:47Z","timestamp":1776432767437,"version":"3.51.2"},"reference-count":44,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Purpose: The primary aim of this study was to determine the efficacy of acute fish oil (FO) supplementation on indices of exercise-induced muscle damage (EIMD) in young healthy adults. Methods: Twenty-two healthy young male and females were randomly assigned to two experimental groups: fish oil (FO) or placebo control (CON). Participants performed a muscle damage protocol consisting of 10 sets of 10 plyometric drop jumps. Vertical jump height, isometric maximal voluntary contraction (MVC) torque, and systemic inflammation markers were assessed at pre-exercise, immediately post (post-0), post-24, post-48, and post-72 h. Results: Vertical jump performance and quadriceps peak torque significantly decreased in the CON group at post-0, 24, and 48 h (p &lt; 0.05), while FO group recovered to baseline levels by post 48 h. Hamstring peak torque reductions recovered in the FO group at post-48 h but remained suppressed in the CON group until post-72 h (p &lt; 0.05). Muscle soreness was significantly higher in the CON group compared to the FO group at post-48 h (p &lt; 0.05). Systemic TNF-\u03b1 levels significantly increased from baseline to post-0, 24, and 48 h in both groups (p &lt; 0.05), with the CON group showing a trend toward incomplete recovery (p = 0.065). Conclusions: Our findings indicate that acute FO administration may modestly aid muscle recovery and reduce muscle soreness following EIMD in healthy young adults while the overall impact may be limited.<\/jats:p>","DOI":"10.3390\/nu17213408","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:50:19Z","timestamp":1761785419000},"page":"3408","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of Acute Fish Oil Supplementation on Muscle Function and Soreness After Eccentric Contraction-Induced Muscle Damage"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0306-3854","authenticated-orcid":false,"given":"Sang-Rok","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Kinesiology, Samford University, Birmingham, AL 35229, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1215-9056","authenticated-orcid":false,"given":"Dean","family":"Directo","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, New Mexico State University, Las Cruces, NM 88003, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangmi","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Exercise Science and Athletic Training, Ithaca College, Ithaca, NY 14850, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Stein","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, New Mexico State University, Las Cruces, NM 88003, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mason","family":"Calvert","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, New Mexico State University, Las Cruces, NM 88003, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7520-3644","authenticated-orcid":false,"given":"Yong Woo","family":"An","sequence":"additional","affiliation":[{"name":"Department of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA 90045, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7556-8632","authenticated-orcid":false,"given":"Do-Houn","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Human Physiology, Gonzaga University, Spokane, WA 99258, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1139\/h99-020","article-title":"Etiology of exercise-induced muscle damage","volume":"24","author":"Clarkson","year":"1999","journal-title":"Can. 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