{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:50:42Z","timestamp":1790787042696,"version":"4.1.0"},"reference-count":34,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fresenius Kabi, Barcelona, Spain"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: The study aimed to characterize perioperative complications and their relationship with nutritional risk in gastrointestinal cancer patients undergoing surgical treatment. Methods: An observational, prospective, and multicenter study was carried out in 469 patients with gastrointestinal malignancies undergoing elective major abdominal surgical procedures in public hospitals throughout Spain. Complications developed during hospitalization and at 30 days after surgery were recorded, and the patients\u2019 nutritional status was evaluated using the MUST screening tool. Results: Colorectal and gastric cancer were the most common tumors. Complications during hospitalization occurred in 146 patients (rate 31.1%). Infections accounted for 68.5% of complications, in particular surgical site infections (SSIs), followed by paralytic ileus (40.4%). At 30 days, the complication rate was 9%, with infections as the most common events. In patients with severe nutritional risk at discharge (MUST score \u2265 2), the percentage of patients with complications was 24.7% as compared to 9.2% in patients without complications (p &lt; 0.0001). Conclusions: Clinicians should be aware of the high frequency of SSIs and that complications are higher among patients with severe nutritional risk. These findings emphasize the need for routine nutritional screening and targeted perioperative support in cancer patients undergoing gastrointestinal cancer surgery.<\/jats:p>","DOI":"10.3390\/nu18020325","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T11:27:58Z","timestamp":1768908478000},"page":"325","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Impact of Malnutrition Risk and Perioperative Complications in Gastrointestinal Cancer Patients Undergoing Elective Major Surgery: A Prospective Observational Multicenter Study"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4335-7208","authenticated-orcid":false,"given":"Manuel","family":"Dur\u00e1n-Poveda","sequence":"first","affiliation":[{"name":"Department of Digestive and General Surgery, Hospital Universitario Rey Juan Carlos, 28933 Madrid, Spain"},{"name":"Department of Medical Specialties and Public Health, Faculty of Health Sciences, Hospital Universitario Rey Juan Carlos, 28933 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8370-6003","authenticated-orcid":false,"given":"Gil","family":"Rodr\u00edguez Caravaca","sequence":"additional","affiliation":[{"name":"Department of Medical Specialties and Public Health, Faculty of Health Sciences, Hospital Universitario Rey Juan Carlos, 28933 Madrid, Spain"},{"name":"Service of Preventive Medicine, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, 28922 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1139-8547","authenticated-orcid":false,"given":"Alejandro","family":"Su\u00e1rez-de-la-Rica","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Surgical Care, Hospital Universitario de La Princesa, 28006 Madrid, Spain"},{"name":"Facultad de Ciencias Biom\u00e9dicas y de la Salud, Universidad Alfonso X el Sabio (UAX), 28691 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9116-7202","authenticated-orcid":false,"given":"Diego","family":"Rodr\u00edguez Villar","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Hospital Ram\u00f3n y Cajal, 28034 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0226-286X","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Pernaute","sequence":"additional","affiliation":[{"name":"Department of Digestive and General Surgery, Hospital Cl\u00ednico San Carlos, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0170-6243","authenticated-orcid":false,"given":"Emilia","family":"Cancer Minchot","sequence":"additional","affiliation":[{"name":"Service of Endocrinology and Nutrition, Hospital Universitario de Fuenlabrada, 28942 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6494-6717","authenticated-orcid":false,"given":"Julia","family":"Bret\u00f3n","sequence":"additional","affiliation":[{"name":"Service of Endocrinology and Nutrition, Hospital Universitario \u201cLozano Blesa\u201d, 50009 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4084-0501","authenticated-orcid":false,"given":"Tamara","family":"D\u00edaz-Vico","sequence":"additional","affiliation":[{"name":"Department of Digestive and General Surgery, Hospital Universitario Rey Juan Carlos, 28933 Madrid, Spain"},{"name":"Department of Medical Specialties and Public Health, Faculty of Health Sciences, Hospital Universitario Rey Juan Carlos, 28933 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7175-8017","authenticated-orcid":false,"given":"Brezo","family":"Mart\u00ednez-Amores","sequence":"additional","affiliation":[{"name":"Department of Medical Specialties and Public Health, Faculty of Health Sciences, Hospital Universitario Rey Juan Carlos, 28933 Madrid, Spain"},{"name":"Department of Medical Oncology, Hospital Universitario Rey Juan Carlos, 28933 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1007\/s00268-016-3600-4","article-title":"Perioperative complications are associated with adverse long-term prognosis and affect the cause of death after general surgery","volume":"40","author":"Tjeertes","year":"2016","journal-title":"World J. 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