{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:13:23Z","timestamp":1777896803549,"version":"3.51.4"},"reference-count":95,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>There is currently no treatment for Parkinson\u2019s (PD) and Alzheimer\u2019s (AD) diseases, and medications that target the blockage of amyloid plaque cascades appear to be the most promising for preventing these diseases. However, it is believed that consuming natural antioxidants, particularly phytochemicals such as phenolic compounds, may help the treatment process for neurodegenerative illnesses. Phenolic substances such as phenolic acids, polyphenols, and flavonoids have been shown to have antioxidant properties in plants and are thought to have a similar impact in humans. This review provides an analysis of the current landscape of PD and AD pathophysiology, paying particular attention to phytochemical-based therapeutic, preventive, and management strategies using disclosed herb candidates in in vivo\/vitro studies. We also highlight the herb-derived components that have recently been identified for their effects in the treatment of PD\/AD to provide a review and perspectives for the development of the next generation of drugs and preparations for the treatment of PD\/AD.<\/jats:p>","DOI":"10.3390\/nu18030439","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T10:08:57Z","timestamp":1769681337000},"page":"439","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Neuroprotective Herbs Associated with Parkinson\u2019s and Alzheimer\u2019s Disease"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5543-2001","authenticated-orcid":false,"given":"Georgiana Smaranda","family":"Mar\u021bi\u0219","sequence":"first","affiliation":[{"name":"Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 64 Calea Floresti, 400509 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8095-8937","authenticated-orcid":false,"given":"Rodica Ana","family":"Ungur","sequence":"additional","affiliation":[{"name":"Department of Medical Specialties, Faculty of Medicine, \u201cIuliu-Ha\u021bieganu\u201d University of Medicine and Pharmacy, 8 Victor Babe\u0219 Street, 400012 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3582-1258","authenticated-orcid":false,"given":"Anamaria","family":"Pop","sequence":"additional","affiliation":[{"name":"Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 64 Calea Floresti, 400509 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelina Maria","family":"Bordean","sequence":"additional","affiliation":[{"name":"Raluca Ripan Technical College, 21th Bistritei, 400430 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3599-5506","authenticated-orcid":false,"given":"Claudia","family":"Pa\u0219ca","sequence":"additional","affiliation":[{"name":"Department of Apiculture and Sericulture, Faculty of Animal Science and Biotechnologies, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Calea M\u0103n\u0103\u015ftur 3\u20135, 400372 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6337-8831","authenticated-orcid":false,"given":"Ileana Monica","family":"Borda","sequence":"additional","affiliation":[{"name":"Department of Medical Specialties, Faculty of Medicine, \u201cIuliu-Ha\u021bieganu\u201d University of Medicine and Pharmacy, 8 Victor Babe\u0219 Street, 400012 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e11440","DOI":"10.1016\/j.heliyon.2022.e11440","article-title":"Potential therapeutic use of plant flavonoids in AD and PD","volume":"8","author":"Sun","year":"2022","journal-title":"Heliyon"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Baranowska-Wojcik, E., Gajowniczek-Alasa, D., Pawlikowska-Pawlega, B., and Szwajgier, D. 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