{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T03:03:33Z","timestamp":1791601413593,"version":"4.3.4"},"reference-count":143,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Cordyceps militaris is an entomopathogenic fungus traditionally used in Asian ethnomedicine and increasingly investigated for its potential health-promoting properties, including immunomodulatory and anti-inflammatory activities. In recent years, it has gained attention as a dietary supplement with possible applications in sports nutrition. This narrative review summarizes and critically evaluates the current human evidence regarding the ergogenic and post-exercise recovery effects of C. militaris supplementation in healthy individuals. A structured database search was conducted using predefined eligibility criteria, and the methodological quality of included studies was appraised through domain-based risk-of-bias assessment. Five intervention studies published between 2017 and 2024, comprising 321 participants aged 16\u201335 years, were identified. Supplementation protocols ranged from 1 to 16 weeks, with daily doses of 1\u201312 g administered either as isolated fungal material or as a part of multi-ingredient formulations. Assessed outcomes included indices of aerobic performance and exercise capacity, such as maximal or peak oxygen uptake (VO2max\/VO2peak), time to exhaustion, power output, running performance, and maintenance of peripheral oxygen saturation during high-intensity exercise. Several studies also evaluated biochemical markers related to muscle damage and inflammatory responses, including creatine kinase, blood urea nitrogen, and white blood cell counts. Although some studies reported improvements in selected performance and recovery parameters, the findings were inconsistent. The certainty of the evidence is limited by small sample sizes, heterogeneity of participants and exercise protocols, insufficient reporting of randomization, lack of trial registration in most studies, absence of standardized preparations with quantified bioactive constituents, and the use of multi-ingredient supplements. Well-designed randomized controlled trials using chemically characterized preparations and homogeneous athletic populations are required to clarify the efficacy and practical relevance of C. militaris in sports nutrition.<\/jats:p>","DOI":"10.3390\/nu18050781","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T17:05:16Z","timestamp":1772211916000},"page":"781","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in Humans\u2014A Narrative Review"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7696-869X","authenticated-orcid":false,"given":"Maciej","family":"J\u0119drejko","sequence":"first","affiliation":[{"name":"Department of Medicinal Plant and Mushroom Biotechnology, Medical College, Jagiellonian University, 9 Medyczna Street, 30-688 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5301-2396","authenticated-orcid":false,"given":"Karol","family":"J\u0119drejko","sequence":"additional","affiliation":[{"name":"Department of Medicinal Plant and Mushroom Biotechnology, Medical College, Jagiellonian University, 9 Medyczna Street, 30-688 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5779-4505","authenticated-orcid":false,"given":"Dominika","family":"Granda","sequence":"additional","affiliation":[{"name":"Department of Nutrition Physiology, Institute of Sport-National Research Institute, 01-982 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8354-211X","authenticated-orcid":false,"given":"Katarzyna","family":"Ka\u0142a","sequence":"additional","affiliation":[{"name":"Department of Medicinal Plant and Mushroom Biotechnology, Medical College, Jagiellonian University, 9 Medyczna Street, 30-688 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4217-7560","authenticated-orcid":false,"given":"Andrzej","family":"Pokrywka","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Pharmacogenomics, Faculty of Pharmacy, Medical University of Warsaw, 02-097 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5007-1486","authenticated-orcid":false,"given":"Bo\u017cena","family":"Muszy\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Medicinal Plant and Mushroom Biotechnology, Medical College, Jagiellonian University, 9 Medyczna Street, 30-688 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1080\/00221473.1969.10613918","article-title":"The Facts about Ergogenic Aids and Sports Performance","volume":"40","author":"Fowler","year":"1969","journal-title":"J. Health Phys. Educ. Recreat."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1079\/095442299108728956","article-title":"Nutritional Ergogenic Aids and Exercise Performance","volume":"12","author":"Maughan","year":"1999","journal-title":"Nutr. Res. Rev."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1123\/ijsnem.2018-0026","article-title":"Dietary Supplements and the High-Performance Athlete","volume":"28","author":"Maughan","year":"2018","journal-title":"Int. J. Sport Nutr. Exerc. Metab."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1123\/ijsnem.2018-0020","article-title":"IOC Consensus Statement: Dietary Supplements and the High-Performance Athlete","volume":"28","author":"Maughan","year":"2018","journal-title":"Int. J. Sport Nutr. Exerc. Metab."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1136\/bjsports-2019-101961","article-title":"UEFA Expert Group Statement on Nutrition in Elite Football. Current Evidence to Inform Practical Recommendations and Guide Future Research","volume":"55","author":"Collins","year":"2021","journal-title":"Br. J. Sports Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"869S","DOI":"10.1093\/jn\/127.5.869S","article-title":"Search for the Competitive Edge: A History of Dietary Fads and Supplements","volume":"127","author":"Applegate","year":"1997","journal-title":"J. Nutr."},{"key":"ref_7","unstructured":"Andr\u00e9n-Sandberg, \u00c5. (2016). The History of Doping and Anti-Doping. A Systematic Collection of Published Scientific Literature 2000\u20132015, Publishing house of the Department of Surgery, Karolinska Institutet at Karolinska University Hospital."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Mottram, D.R., and Chester, N. (2022). Drugs in Sport, Routledge.","DOI":"10.4324\/9781003096160"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Das, G., Shin, H.-S., Leyva-G\u00f3mez, G., Del Prado-Audelo, M.L., Cortes, H., Singh, Y.D., Panda, M.K., Mishra, A.P., Nigam, M., and Saklani, S. (2021). Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials. Front. Pharmacol., 11.","DOI":"10.3389\/fphar.2020.602364"},{"key":"ref_10","unstructured":"European Comission (EC) (2025, November 01). Novel Food Status Catalogue. Available online: https:\/\/ec.europa.eu\/food\/food-feed-portal\/screen\/novel-food-catalogue."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Pal, M., and Misra, K. (2018). Cordyceps sp.: The Precious Mushroom for High-Altitude Maladies. Management of High Altitude Pathophysiology, Elsevier.","DOI":"10.1016\/B978-0-12-813999-8.00006-9"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"142548","DOI":"10.1016\/j.scitotenv.2020.142548","article-title":"Chinese Caterpillar Fungus (Ophiocordyceps sinensis) in China: Current Distribution, Trading, and Futures under Climate Change and Overexploitation","volume":"755","author":"Wei","year":"2021","journal-title":"Sci. Total Environ."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"114215","DOI":"10.1016\/j.jep.2021.114215","article-title":"Discovery of the Signal Pathways and Major Bioactive Compounds Responsible for the Anti-Hypoxia Effect of Chinese Cordyceps","volume":"277","author":"Long","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1089\/jmf.2014.3350","article-title":"Cordyceps militaris Enhances Cell-Mediated Immunity in Healthy Korean Men","volume":"18","author":"Kang","year":"2015","journal-title":"J. Med. Food"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"258","DOI":"10.4163\/jnh.2019.52.3.258","article-title":"Effects of Cordyceps militaris Supplementation on the Immune Response and Upper Respiratory Infection in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study","volume":"52","author":"Jung","year":"2019","journal-title":"J. Nutr. Health"},{"key":"ref_16","first-page":"169","article-title":"The Efficacy of Cordyceps militaris Capsules in Treatment of Chronic Bronchitis","volume":"13","author":"Gai","year":"2004","journal-title":"Chin. New Drug J."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.ijbiomac.2019.04.020","article-title":"Advance in Cordyceps militaris (Linn) Link Polysaccharides: Isolation, Structure, and Bioactivities: A Review","volume":"132","author":"Zhang","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"174616","DOI":"10.1155\/2015\/174616","article-title":"Studies on the Antifatigue Activities of Cordyceps militaris Fruit Body Extract in Mouse Model","volume":"2015","author":"Song","year":"2015","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1615\/IntJMedMushrooms.v18.i12.30","article-title":"Effect of Polysaccharide from Cordyceps militaris (Ascomycetes) on Physical Fatigue Induced by Forced Swimming","volume":"18","author":"Xu","year":"2016","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s12970-017-0171-1","article-title":"Evaluation of Anti-Fatigue Property of the Extruded Product of Cereal Grains Mixed with Cordyceps militaris on Mice","volume":"14","author":"Zhong","year":"2017","journal-title":"J. Int. Soc. Sports Nutr."},{"key":"ref_21","unstructured":"Corchane Methods Bias (2025, November 01). RoB 2: A Revised Cochrane Risk-of-Bias Tool for Randomized Trials. Available online: https:\/\/methods.cochrane.org\/bias\/resources\/rob-2-revised-cochrane-risk-bias-tool-randomized-trials."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1080\/19390211.2016.1203386","article-title":"Cordyceps militaris Improves Tolerance to High-Intensity Exercise After Acute and Chronic Supplementation","volume":"14","author":"Hirsch","year":"2017","journal-title":"J. Diet. Suppl."},{"key":"ref_23","first-page":"1","article-title":"The Effects of High and Low-Dose Cordyceps Militaris-Containing Mushroom Blend Supplementation After Seven and Twenty-Eight Days","volume":"6","year":"2018","journal-title":"Am. J. Sports Sci."},{"key":"ref_24","first-page":"2802","article-title":"Effects of Cordyceps militaris Effective Substances on the Physical Function of Athletes","volume":"12","author":"Wang","year":"2021","journal-title":"J. Food Saf. Qual."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Nakamura, A., Shinozaki, E., Suzuki, Y., Santa, K., Kumazawa, Y., Kobayashi, F., Nagaoka, I., and Koikawa, N. (2024). Effect of the Administration of Cordyceps militaris Mycelium Extract on Blood Markers for Anemia in Long-Distance Runners. Nutrients, 16.","DOI":"10.3390\/nu16121835"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3923\/ajbs.2024.85.92","article-title":"Improved Oxygen Saturation and Performance of Athletes Using Cordyceps militaris","volume":"17","author":"Pasha","year":"2024","journal-title":"Asian J. Biol. Sci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s13668-025-00690-9","article-title":"Ergogenic Aid by Cordyceps: Does It Work??","volume":"14","author":"Dewi","year":"2025","journal-title":"Curr. Nutr. Rep."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"P45","DOI":"10.1186\/1550-2783-12-S1-P45","article-title":"Chronic Supplementation of a Mushroom Blend on Oxygen Kinetics, Peak Power, and Time to Exhaustion","volume":"12","author":"Hirsch","year":"2015","journal-title":"J. Int. Soc. Sports Nutr."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Ler, H.Y., Tan, J.Y., and Chan, K.Q. (2023). Effect of Cordyceps militaris, Arginine and Citrulline Supplementation on Long Distance Runners in Hot Conditions. Proceedings of the 8th International Conference on Movement, Health and Exercise, Springer.","DOI":"10.1007\/978-981-99-2162-1_32"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"J\u0119drejko, K.J., Lazur, J., and Muszy\u0144ska, B. (2021). Cordyceps militaris: An Overview of Its Chemical Constituents in Relation to Biological Activity. Foods, 10.","DOI":"10.3390\/foods10112634"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"8141","DOI":"10.1038\/s41598-025-92790-3","article-title":"Cordycepin Combined with Antioxidant Effects Improves Fatigue Caused by Excessive Exercise","volume":"15","author":"Cheng","year":"2025","journal-title":"Sci. Rep."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"vvaf097","DOI":"10.1093\/ijfood\/vvaf097","article-title":"Determination of Cordycepin, Ergothioneine, and Other Bioactive Compounds in Cordyceps militaris Fruiting Bodies Cultivated on Different Substrates","volume":"60","author":"Krakowska","year":"2025","journal-title":"Int. J. Food Sci. Technol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1615\/IntJMedMushr.v16.i3.80","article-title":"Chemical Composition and Nutritional and Medicinal Value of Fruit Bodies and Submerged Cultured Mycelia of Culinary-Medicinal Higher Basidiomycetes Mushrooms","volume":"16","author":"Cohen","year":"2014","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_34","first-page":"74","article-title":"Comparison of Bioactive Compoundscontained in Discard Solid State Culture and Cordyceps militaris fruiting Bodywines","volume":"13","author":"Labua","year":"2023","journal-title":"J. Curr. Sci. Technol."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Radhi, M., Ashraf, S., Lawrence, S., Tranholm, A.A., Wellham, P.A.D., Hafeez, A., Khamis, A.S., Thomas, R., McWilliams, D., and de Moor, C.H. (2021). A Systematic Review of the Biological Effects of Cordycepin. Molecules, 26.","DOI":"10.3390\/molecules26195886"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Qin, P., Li, X., Yang, H., Wang, Z.-Y., and Lu, D. (2019). Therapeutic Potential and Biological Applications of Cordycepin and Metabolic Mechanisms in Cordycepin-Producing Fungi. Molecules, 24.","DOI":"10.3390\/molecules24122231"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Ashraf, S.A., Elkhalifa, A.E.O., Siddiqui, A.J., Patel, M., Awadelkareem, A.M., Snoussi, M., Ashraf, M.S., Adnan, M., and Hadi, S. (2020). Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Medicinal Fungus Cordyceps with Its Nutraceutical and Therapeutic Potential. Molecules, 25.","DOI":"10.3390\/molecules25122735"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"342","DOI":"10.3923\/ajft.2011.342.347","article-title":"Nutraceutical Market and Its Regulation","volume":"6","author":"Ahmad","year":"2011","journal-title":"Am. J. Food Technol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1080\/12298093.2020.1831135","article-title":"Beneficial Effect of Cordyceps militaris on Exercise Performance via Promoting Cellular Energy Production","volume":"48","author":"Choi","year":"2020","journal-title":"Mycobiology"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.bbrc.2022.11.010","article-title":"Cordycepin Exhibits Anti-Fatigue Effect via Activating TIGAR\/SIRT1\/PGC-1\u03b1 Signaling Pathway","volume":"637","author":"Chai","year":"2022","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.cca.2014.10.036","article-title":"SIRT1: Role in Cardiovascular Biology","volume":"440","author":"Ma","year":"2015","journal-title":"Clin. Chim. Acta"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"7994","DOI":"10.1038\/s41598-024-58742-z","article-title":"A Randomized Controlled Clinical Trial Examining the Effects of Cordyceps militaris Beverage on the Immune Response in Healthy Adults","volume":"14","author":"Ontawong","year":"2024","journal-title":"Sci. Rep."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1615\/IntJMedMushrooms.v17.i7.50","article-title":"Chemical Composition and Medicinal Value of Fruiting Bodies and Submerged Cultured Mycelia of Caterpillar Medicinal Fungus Cordyceps militaris CBS-132098 (Ascomycetes)","volume":"17","author":"Chan","year":"2015","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1017\/S0954422419000301","article-title":"The Biology of Ergothioneine, an Antioxidant Nutraceutical","volume":"33","author":"Borodina","year":"2020","journal-title":"Nutr. Res. Rev."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"J\u0119drejko, M., Ka\u0142a, K., and Muszy\u0144ska, B. (2025). Anserine, Balenine, and Ergothioneine: Impact of Histidine-Containing Compounds on Exercise Performance\u2014A Narrative Review. Nutrients, 17.","DOI":"10.3390\/nu17050828"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1002\/1873-3468.14350","article-title":"Ergothioneine, Where Are We Now?","volume":"596","author":"Halliwell","year":"2022","journal-title":"FEBS Lett."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.bbrc.2016.07.074","article-title":"Ergothioneine Levels in an Elderly Population Decrease with Age and Incidence of Cognitive Decline; a Risk Factor for Neurodegeneration?","volume":"478","author":"Cheah","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1111\/pcn.13893","article-title":"Serum Ergothioneine and Risk of Dementia in a General Older Japanese Population: The Hisayama Study","volume":"79","author":"Meng","year":"2025","journal-title":"Psychiatry Clin. Neurosci."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1002\/1873-3468.14299","article-title":"Decline of Ergothioneine in Frailty and Cognition Impairment","volume":"596","author":"Kondoh","year":"2022","journal-title":"FEBS Lett."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"152210","DOI":"10.1016\/j.bbrc.2025.152210","article-title":"Characteristics of Ergothioneine Distribution across Skeletal Muscles and Adipose Tissues","volume":"776","author":"Nishioka","year":"2025","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1093\/procel\/pwad048","article-title":"Ergothioneine and Its Congeners: Anti-Ageing Mechanisms and Pharmacophore Biosynthesis","volume":"15","author":"Chen","year":"2024","journal-title":"Protein Cell"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"111921","DOI":"10.1016\/j.biopha.2021.111921","article-title":"L-Ergothioneine and Its Combination with Metformin Attenuates Renal Dysfunction in Type-2 Diabetic Rat Model by Activating Nrf2 Antioxidant Pathway","volume":"141","author":"Dare","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"111982","DOI":"10.1016\/j.exger.2022.111982","article-title":"Ergothioneine and Its Prospects as an Anti-Ageing Compound","volume":"170","author":"Apparoo","year":"2022","journal-title":"Exp. Gerontol."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Sprenger, H.-G., Mittenb\u00fchler, M.J., Sun, Y., Van Vranken, J.G., Schindler, S., Jayaraj, A., Khetarpal, S.A., Vargas-Castillo, A., Puszynska, A.M., and Spinelli, J.B. (2024). Ergothioneine Boosts Mitochondrial Respiration and Exercise Performance via Direct Activation of MPST. bioRxiv.","DOI":"10.1101\/2024.04.10.588849"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Fovet, T., Guilhot, C., Delobel, P., Chopard, A., Py, G., and Brioche, T. (2022). Ergothioneine Improves Aerobic Performance Without Any Negative Effect on Early Muscle Recovery Signaling in Response to Acute Exercise. Front. Physiol., 13.","DOI":"10.3389\/fphys.2022.834597"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s00580-021-03255-8","article-title":"Haematological Profiles and Erythrocyte Fragility of Arabian Stallions Subjected to a 2000-m Maximal Race Following Administration of Ergothioneine","volume":"30","author":"Adah","year":"2021","journal-title":"Comp. Clin. Path."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"163","DOI":"10.20473\/mkh.v33i3.2022.163-176","article-title":"Ergothioneine Modulates Biomarkers of Oxidative Stress, Biochemical Profiles and Rectal Temperatures of Arabian Stallions Following Exercise in A Hot-Humid Environment","volume":"33","author":"Adah","year":"2022","journal-title":"Media Kedokt. Hewan"},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Adah, A.S., Ayo, J.O., Adah, D.A., Nwonuma, C.O., and Lawal, T.A. (2023). Molecular Docking and Experimental Validation of the Effect of Ergothioneine on Heat Shock Protein-70 Following Endurance Exercise by Arabian Stallions. BMC Vet. Res., 19.","DOI":"10.1186\/s12917-023-03584-6"},{"key":"ref_59","first-page":"249","article-title":"Effect of Shiitake (Lentinus edodes) Extract on Antioxidant and Inflammatory Response to Prolonged Eccentric Exercise","volume":"64","author":"Gajewski","year":"2013","journal-title":"J. Physiol. Pharmacol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1089\/ars.2016.6778","article-title":"Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation","volume":"26","author":"Cheah","year":"2017","journal-title":"Antioxid. Redox Signal."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1177\/13872877241291253","article-title":"Investigating the Efficacy of Ergothioneine to Delay Cognitive Decline in Mild Cognitively Impaired Subjects: A Pilot Study","volume":"102","author":"Yau","year":"2024","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"103219","DOI":"10.1016\/j.cdnut.2024.103219","article-title":"The Effect of Ergothioneine Supplementation on Cognitive Function and Other Health-Related Outcomes in Older Adults with Subjective Memory Complaints","volume":"8","author":"Zajac","year":"2024","journal-title":"Curr. Dev. Nutr."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Zajac, I.T., Kakoschke, N., Kuhn-Sherlock, B., and May-Zhang, L.S. (2025). The Effect of Ergothioneine Supplementation on Cognitive Function, Memory, and Sleep in Older Adults with Subjective Memory Complaints: A Randomized Placebo-Controlled Trial. Nutraceuticals, 5.","DOI":"10.3390\/nutraceuticals5030015"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/s41538-024-00250-5","article-title":"TrkB Phosphorylation in Serum Extracellular Vesicles Correlates with Cognitive Function Enhanced by Ergothioneine in Humans","volume":"8","author":"Ishimoto","year":"2024","journal-title":"NPJ Sci. Food"},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Hu, Y., Wu, Y., Song, J., Ma, M., Xiao, Y., and Zeng, B. (2024). Advancing Cordyceps militaris Industry: Gene Manipulation and Sustainable Biotechnological Strategies. Bioengineering, 11.","DOI":"10.3390\/bioengineering11080783"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/s10482-025-02172-y","article-title":"Strain Improvement of Cordyceps militaris for Optimized Bioactive Metabolite Biosynthesis: Current Progress and Prospective Approaches","volume":"118","author":"Meshram","year":"2025","journal-title":"Antonie Van Leeuwenhoek"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/s12934-022-01891-5","article-title":"Enhancement of Ergothioneine Production by Discovering and Regulating Its Metabolic Pathway in Cordyceps militaris","volume":"21","author":"Chen","year":"2022","journal-title":"Microb. Cell Fact."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"S78","DOI":"10.21037\/atm.2019.04.12","article-title":"New Insights into Cordycepin Production in Cordyceps militaris and Applications","volume":"7","author":"Chamyuang","year":"2019","journal-title":"Ann. Transl. Med."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.procbio.2013.10.017","article-title":"Efficient Production of Cordycepin by the Cordyceps militaris Mutant G81-3 for Practical Use","volume":"49","author":"Masuda","year":"2014","journal-title":"Process Biochem."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"31","DOI":"10.5941\/MYCO.2017.45.1.31","article-title":"Development of High Cordycepin-Producing Cordyceps militaris Strains","volume":"45","author":"Kang","year":"2017","journal-title":"Mycobiology"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.enzmictec.2006.09.008","article-title":"Enhanced Production of Cordycepin by Surface Culture Using the Medicinal Mushroom Cordyceps militaris","volume":"40","author":"Masuda","year":"2007","journal-title":"Enzym. Microb. Technol."},{"key":"ref_72","doi-asserted-by":"crossref","unstructured":"Turk, A., Lee, S., Yeon, S.W., Ryu, S.H., Han, Y.K., Kim, Y.J., Ko, S.M., Kim, B.S., Hwang, B.Y., and Lee, K.Y. (2023). Adenosine Deaminase Inhibitory Activity of Medicinal Plants: Boost the Production of Cordycepin in Cordyceps militaris. Antioxidants, 12.","DOI":"10.3390\/antiox12061260"},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Lee, S.K., Lee, J.H., Kim, H.R., Chun, Y., Lee, J.H., Yoo, H.Y., Park, C., and Kim, S.W. (2019). Improved Cordycepin Production by Cordyceps militaris KYL05 Using Casein Hydrolysate in Submerged Conditions. Biomolecules, 9.","DOI":"10.3390\/biom9090461"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"129742","DOI":"10.1016\/j.biortech.2023.129742","article-title":"High-Level Production of Cordycepin by the Xylose-Utilising Cordyceps militaris Strain 147 in an Optimised Medium","volume":"388","author":"Long","year":"2023","journal-title":"Bioresour. Technol."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Phoungthong, K., Aiphuk, W., Maneerat, T., Suwunwong, T., Choto, P., and Chomnunti, P. (2022). Utilization of Corncob Biochar in Cultivation Media for Cordycepin Production and Biomass of Cordyceps militaris. Sustainability, 14.","DOI":"10.3390\/su14159362"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.bej.2011.09.014","article-title":"Enhancement of Cordycepin Production in Submerged Cultures of Cordyceps militaris by Addition of Ferrous Sulfate","volume":"60","author":"Fan","year":"2012","journal-title":"Biochem. Eng. J."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1007\/s12010-011-9506-6","article-title":"Selenium Enrichment on Cordyceps militaris Link and Analysis on Its Main Active Components","volume":"166","author":"Dong","year":"2012","journal-title":"Appl. Biochem. Biotechnol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/s12011-018-1386-y","article-title":"Selenium Biofortification and Antioxidant Activity in Cordyceps militaris Supplied with Selenate, Selenite, or Selenomethionine","volume":"187","author":"Hu","year":"2019","journal-title":"Biol. Trace Elem. Res."},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"Turk, A., Abdelhamid, M.A.A., Yeon, S.W., Ryu, S.H., Lee, S., Ko, S.M., Kim, B.S., Pack, S.P., Hwang, B.Y., and Lee, M.K. (2022). Cordyceps mushroom with Increased Cordycepin Content by the Cultivation on Edible Insects. Front. Microbiol., 13.","DOI":"10.3389\/fmicb.2022.1017576"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.biortech.2018.07.128","article-title":"Enhancing Cordycepin Production in Liquid Static Cultivation of Cordyceps militaris by Adding Vegetable Oils as the Secondary Carbon Source","volume":"268","author":"Tang","year":"2018","journal-title":"Bioresour. Technol."},{"key":"ref_81","doi-asserted-by":"crossref","unstructured":"Park, H.-J. (2025). Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review. Foods, 14.","DOI":"10.3390\/foods14193408"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1080\/19476337.2017.1325406","article-title":"Effect of PH, Temperature and Incubation Time on Cordycepin Production from Cordyceps militaris Using Solid-State Fermentation on Various Substrates","volume":"15","author":"Adnan","year":"2017","journal-title":"CyTA-J. Food"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1080\/10942912.2024.2373781","article-title":"Growth of Cordyceps militaris Cultivation and Its Bioactive Component Accumulation as Affected by Various Single-Wavelength Light-Emitting Diodes (LED) Light Sources","volume":"27","author":"Lin","year":"2024","journal-title":"Int. J. Food Prop."},{"key":"ref_84","doi-asserted-by":"crossref","unstructured":"Wang, Y., Yang, Z., Bao, D., Li, B., Yin, X., Wu, Y., Chen, H., Tang, G., Li, N., and Zou, G. (2021). Improving Hypoxia Adaption Causes Distinct Effects on Growth and Bioactive Compounds Synthesis in an Entomopathogenic Fungus Cordyceps militaris. Front. Microbiol., 12.","DOI":"10.3389\/fmicb.2021.698436"},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Kontogiannatos, D., Koutrotsios, G., Xekalaki, S., and Zervakis, G.I. (2021). Biomass and Cordycepin Production by the Medicinal Mushroom Cordyceps militaris\u2014A Review of Various Aspects and Recent Trends towards the Exploitation of a Valuable Fungus. J. Fungi, 7.","DOI":"10.3390\/jof7110986"},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Trung, N.Q., Quyen, P.D.T., Ngoc, N.T.T., and Minh, T.N. (2024). Diversity of Host Species and Optimized Cultivation Practices for Enhanced Bioactive Compound Production in Cordyceps militaris. Appl. Sci., 14.","DOI":"10.3390\/app14188418"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1007\/s42770-023-01169-x","article-title":"Enhanced Production of Cordycepin under Solid-State Fermentation of Cordyceps militaris by Using Combinations of Grains\/Substrates","volume":"54","author":"Borde","year":"2023","journal-title":"Braz. J. Microbiol."},{"key":"ref_88","first-page":"e05060","article-title":"Statement on the Safety of Synthetic L-ergothioneine as a Novel Food\u2014Supplementary Dietary Exposure and Safety Assessment for Infants and Young Children, Pregnant and Breastfeeding Women","volume":"15","author":"Turck","year":"2017","journal-title":"EFSA J."},{"key":"ref_89","doi-asserted-by":"crossref","unstructured":"Vali\u00f1o-Marques, A., Lamas, A., Miranda, J.M., Cepeda, A., and Regal, P. (2024). Nutritional Ergogenic Aids in Cycling: A Systematic Review. Nutrients, 16.","DOI":"10.3390\/nu16111768"},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"Bongiovanni, T., Genovesi, F., Carling, C., Greco, G., and J\u00e4ger, R. (2025). From Science to Dressing Room: Dietary Supplements for Elite Soccer Performance. J. Funct. Morphol. Kinesiol., 10.","DOI":"10.3390\/jfmk10040408"},{"key":"ref_91","doi-asserted-by":"crossref","unstructured":"Chen, B.-X., Wei, T., Xue, L.-N., Zheng, Q.-W., Ye, Z.-W., Zou, Y., Yang, Y., Yun, F., Guo, L.-Q., and Lin, J.-F. (2020). Transcriptome Analysis Reveals the Flexibility of Cordycepin Network in Cordyceps militaris Activated by L-Alanine Addition. Front. Microbiol., 11.","DOI":"10.3389\/fmicb.2020.00577"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"589","DOI":"10.38212\/2224-6614.3529","article-title":"Alanine Supplementation Enhancing Cordycepin Production in Cordyceps militaris via Upregulation of Cns2 and Cns3 Genes Expression Levels","volume":"32","author":"Yu","year":"2024","journal-title":"J. Food Drug Anal."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1123\/ijsnem.2013-0173","article-title":"Cycling Time Trial Performance May Be Impaired by Whey Protein and L-Alanine Intake During Prolonged Exercise","volume":"24","author":"Schroer","year":"2014","journal-title":"Int. J. Sport Nutr. Exerc. Metab."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s00726-008-0187-6","article-title":"The Effects of Alanine Ingestion on Metabolic Responses to Exercise in Cyclists","volume":"37","author":"Klein","year":"2009","journal-title":"Amino Acids"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1123\/ijsnem.2015-0137","article-title":"Amino Acid Mixture Enriched With Arginine, Alanine, and Phenylalanine Stimulates Fat Metabolism During Exercise","volume":"26","author":"Ueda","year":"2016","journal-title":"Int. J. Sport Nutr. Exerc. Metab."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1080\/09168451.2017.1303359","article-title":"Combination of Aerobic Exercise and an Arginine, Alanine, and Phenylalanine Mixture Increases Fat Mobilization and Ketone Body Synthesis","volume":"81","author":"Ueda","year":"2017","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"325","DOI":"10.7600\/jpfsm.6.325","article-title":"An Arginine, Alanine, and Phenylalanine Mixture Increases Synthesis of Ketone Bodies during Low-Intensity Exercise via Stimulating Glucagon Secretion in Men with Obesity","volume":"6","author":"Ueda","year":"2017","journal-title":"J. Phys. Fit. Sports Med."},{"key":"ref_98","doi-asserted-by":"crossref","unstructured":"Mantuano, P., Bianchini, G., Cappellari, O., Boccanegra, B., Conte, E., Sanarica, F., Mele, A., Camerino, G.M., Brandolini, L., and Allegretti, M. (2020). Ergogenic Effect of BCAAs and L-Alanine Supplementation: Proof-of-Concept Study in a Murine Model of Physiological Exercise. Nutrients, 12.","DOI":"10.3390\/nu12082295"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1139\/apnm-2016-0049","article-title":"l-Glutamine and l-Alanine Supplementation Increase Glutamine-Glutathione Axis and Muscle HSP-27 in Rats Trained Using a Progressive High-Intensity Resistance Exercise","volume":"41","author":"Leite","year":"2016","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1080\/19390211.2018.1470129","article-title":"Acute Effect of Oral N-Acetylcysteine on Muscle Soreness and Exercise Performance in Semi-Elite Rugby Players","volume":"16","author":"Rhodes","year":"2019","journal-title":"J. Diet. Suppl."},{"key":"ref_101","doi-asserted-by":"crossref","unstructured":"Fern\u00e1ndez-L\u00e1zaro, D., Dom\u00ednguez-Ortega, C., Busto, N., Santamar\u00eda-Pel\u00e1ez, M., Roche, E., Guti\u00e9rez-Abej\u00f3n, E., and Mielgo-Ayuso, J. (2023). Influence of N-Acetylcysteine Supplementation on Physical Performance and Laboratory Biomarkers in Adult Males: A Systematic Review of Controlled Trials. Nutrients, 15.","DOI":"10.3390\/nu15112463"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1249\/MSS.0b013e3182019a78","article-title":"Effectiveness of Sulfur-Containing Antioxidants in Delaying Skeletal Muscle Fatigue","volume":"43","author":"Ferreira","year":"2011","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"219","DOI":"10.7600\/jpfsm.10.219","article-title":"Effects of Pycnogenol-Containing Supplement on Professional Cycling Performance: A Single-Group Pretest-Posttest Pilot Study","volume":"10","author":"Hara","year":"2021","journal-title":"J. Phys. Fit. Sports Med."},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Fern\u00e1ndez-L\u00e1zaro, D., Arribalzaga, S., Guti\u00e9rrez-Abej\u00f3n, E., Azarbayjani, M.A., Mielgo-Ayuso, J., and Roche, E. (2024). Omega-3 Fatty Acid Supplementation on Post-Exercise Inflammation, Muscle Damage, Oxidative Response, and Sports Performance in Physically Healthy Adults\u2014A Systematic Review of Randomized Controlled Trials. Nutrients, 16.","DOI":"10.3390\/nu16132044"},{"key":"ref_105","first-page":"101002","article-title":"Chitosan Oligosaccharides-Modified Nanoliposome Improve the Stability, Antioxidant, and Anti-Inflammatory Activity of Cordycepin","volume":"11","author":"Jiao","year":"2025","journal-title":"Carbohydr. Polym. Technol. Appl."},{"key":"ref_106","doi-asserted-by":"crossref","unstructured":"Yang, J., Tao, L., Lou, D., Patabendige, N.M., Ediriweera, A.N., Liu, S., Lu, W., Tarafder, E., Rapior, S., and Hapuarachchi, K.K. (2025). Innovative Applications of Medicinal Mushrooms in Functional Foods and Nutraceuticals: A Focus on Health-Boosting Beverages. Front. Cell. Infect. Microbiol., 15.","DOI":"10.3389\/fcimb.2025.1605301"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"e14169","DOI":"10.1111\/jfpp.14169","article-title":"Effects of Superfine Grinding on the Properties and Qualities of Cordyceps militaris and Its Spent Substrate","volume":"43","author":"Shi","year":"2019","journal-title":"J. Food Process. Preserv."},{"key":"ref_108","doi-asserted-by":"crossref","unstructured":"Ka\u0142a, K., Cicha-Jele\u0144, M., Hnatyk, K., Krakowska, A., Su\u0142kowska-Ziaja, K., Szewczyk, A., Lazur, J., and Muszy\u0144ska, B. (2024). Coffee with Cordyceps militaris and Hericium erinaceus Fruiting Bodies as a Source of Essential Bioactive Substances. Pharmaceuticals, 17.","DOI":"10.3390\/ph17070955"},{"key":"ref_109","doi-asserted-by":"crossref","unstructured":"Vito\u0161evi\u0107, B., Filipovi\u0107, M., Popovi\u0107, L., Sterkowicz-Przybycie\u0144, K., and Purenovi\u0107-Ivanovi\u0107, T. (2025). Juice-Based Supplementation Strategies for Athletic Performance and Recovery: A Systematic Review. Sports, 13.","DOI":"10.37766\/inplasy2025.6.0053"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.jsams.2007.10.007","article-title":"The Reliability of the 1RM Strength Test for Untrained Middle-Aged Individuals","volume":"12","author":"Levinger","year":"2009","journal-title":"J. Sci. Med. Sport"},{"key":"ref_111","doi-asserted-by":"crossref","unstructured":"de C\u00e1ssia Macedo, M., Souza, M.A., Ferreira, K.R., Campos, L.O., Souza, I.S.O., Barbosa, M.A., Brito, C.J., Intelangelo, L., and Barbosa, A.C. (2022). Validity and Test-Retest Reliability of a Novel Push Low-Cost Hand-Held Dynamometer for Knee Strength Assessment during Different Force Ranges. Diagnostics, 12.","DOI":"10.3390\/diagnostics12010186"},{"key":"ref_112","doi-asserted-by":"crossref","unstructured":"G\u00e1l-Pottyondy, A., Petr\u00f3, B., Cz\u00e9t\u00e9nyi, A., N\u00e9gyesi, J., Nagatomi, R., and Kiss, R.M. (2021). Collection and Advice on Basketball Field Tests\u2014A Literature Review. Appl. Sci., 11.","DOI":"10.3390\/app11198855"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"239","DOI":"10.2478\/hukin-2021-0094","article-title":"Design of a Tennis-Specific Agility Test (TAT) for Monitoring Tennis Players","volume":"80","author":"Jansen","year":"2021","journal-title":"J. Hum. Kinet."},{"key":"ref_114","first-page":"116","article-title":"Sports Musculoskeletal Injury in the Professional Athlete with Clinical and Rehabilitation Point","volume":"4","author":"Saffarijourshari","year":"2025","journal-title":"Eurasian J. Chem. Med. Pet. Res."},{"key":"ref_115","doi-asserted-by":"crossref","unstructured":"Martonovich, N., Maman, D., Mahamid, A., Alfandari, L., and Behrbalk, E. (2025). The Wrist as a Weightbearing Joint in Adult Handstand Practitioners: A Cross-Sectional Survey of Chronic Pain and Training-Related Factors. J. Funct. Morphol. Kinesiol., 10.","DOI":"10.3390\/jfmk10040372"},{"key":"ref_116","doi-asserted-by":"crossref","unstructured":"Pham, H., and Spaniol, F. (2024). The Efficacy of Non-Steroidal Anti-Inflammatory Drugs in Athletes for Injury Management, Training Response, and Athletic Performance: A Systematic Review. Sports, 12.","DOI":"10.3390\/sports12110302"},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jsams.2024.08.201","article-title":"The Impact of Injuries on Sports-Related Analgesic Use in Danish Youth Elite Athletes: A 4-Week Prospective Cohort Study","volume":"28","author":"Larsen","year":"2025","journal-title":"J. Sci. Med. Sport"},{"key":"ref_118","doi-asserted-by":"crossref","unstructured":"Christopher, S., Tadlock, B.A., Veroneau, B.J., Harnish, C., Perera, N.K.P., Knab, A.M., Vallabhajosula, S., and Bullock, G.S. (2020). Epidemiological Profile of Pain and Non-Steroid Anti-Inflammatory Drug Use in Collegiate Athletes in the United States. BMC Musculoskelet. Disord., 21.","DOI":"10.1186\/s12891-020-03581-y"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"e001846","DOI":"10.1136\/bmjsem-2023-001846","article-title":"What Is Known about the Health Effects of Non-Steroidal Anti-Inflammatory Drug (NSAID) Use in Marathon and Ultraendurance Running: A Scoping Review","volume":"10","author":"Pannone","year":"2024","journal-title":"BMJ Open Sport Exerc. Med."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s40798-020-00247-w","article-title":"Effect of Non-Steroidal Anti-Inflammatory Drugs on Sport Performance Indices in Healthy People: A Meta-Analysis of Randomized Controlled Trials","volume":"6","author":"Cornu","year":"2020","journal-title":"Sports Med. Open"},{"key":"ref_121","doi-asserted-by":"crossref","unstructured":"Phull, A.-R., Ahmed, M., and Park, H.-J. (2022). Cordyceps militaris as a Bio Functional Food Source: Pharmacological Potential, Anti-Inflammatory Actions and Related Molecular Mechanisms. Microorganisms, 10.","DOI":"10.3390\/microorganisms10020405"},{"key":"ref_122","doi-asserted-by":"crossref","unstructured":"Broeckel, J., Estes, L., Leonard, M., Dickerson, B.L., Gonzalez, D.E., Purpura, M., J\u00e4ger, R., Sowinski, R.J., Rasmussen, C.J., and Kreider, R.B. (2025). Effects of Ginger Supplementation on Markers of Inflammation and Functional Capacity in Individuals with Mild to Moderate Joint Pain. Nutrients, 17.","DOI":"10.3390\/nu17142365"},{"key":"ref_123","doi-asserted-by":"crossref","unstructured":"Salter, D., Yalamanchi, H., Yalamanchi, A., and Yalamanchi, A. (2025). Ten Days of Supplementation with a Standardized Boswellia Serrata Extract Attenuates Soreness and Accelerates Recovery after Repeated Bouts of Downhill Running in Recreationally Active Men. Front. Sports Act. Living, 7.","DOI":"10.3389\/fspor.2025.1488821"},{"key":"ref_124","first-page":"1","article-title":"Combined Effects of Turmeric Supplementation and Strengthening Exercises on Knee Pain, Physical Function, and Quality of Life among Knee Osteoarthritis Patients","volume":"13","author":"Ramakrishnan","year":"2025","journal-title":"Ann. Appl. Sport Sci."},{"key":"ref_125","doi-asserted-by":"crossref","unstructured":"J\u0119drejko, K., Ka\u0142a, K., Su\u0142kowska-Ziaja, K., Pytko-Polo\u0144czyk, J., and Muszy\u0144ska, B. (2022). Effect of Cordyceps spp. and Cordycepin on Functions of Bones and Teeth and Related Processes: A Review. Molecules, 27.","DOI":"10.3390\/molecules27238170"},{"key":"ref_126","unstructured":"National Institutes of Health (NIH) (2025, November 20). Dietary Supplement Label Database, Available online: https:\/\/dsld.od.nih.gov\/."},{"key":"ref_127","doi-asserted-by":"crossref","unstructured":"Walpurgis, K., Thomas, A., Geyer, H., Mareck, U., and Thevis, M. (2020). Dietary Supplement and Food Contaminations and Their Implications for Doping Controls. Foods, 9.","DOI":"10.3390\/foods9081012"},{"key":"ref_128","doi-asserted-by":"crossref","unstructured":"Pokrywka, A., Morawin, B., Krzywa\u0144ski, J., and Zembro\u0144-Lacny, A. (2017). An Overview on Tribulus terrestris in Sports Nutrition and Energy Regulation. Sustained Energy for Enhanced Human Functions and Activity, Elsevier.","DOI":"10.1016\/B978-0-12-805413-0.00009-0"},{"key":"ref_129","unstructured":"Food and Drug Administration Ministry of Health and Welfare (2025, November 20). Act Governing Food Safety and Sanitation. Available online: https:\/\/faolex.fao.org\/docs\/pdf\/tw137915E.pdf."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1080\/87559129.2023.2238055","article-title":"Ergogenic Properties, Safety Evaluation and Regulations of Selected Ingredients in Testosterone Booster Dietary Supplements","volume":"40","author":"Lazarev","year":"2024","journal-title":"Food Rev. Int."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"100143","DOI":"10.1016\/j.prmcm.2022.100143","article-title":"The Effects of Cordyceps militaris Fruiting Bodies in Micturition and Prostate Size in Benign Prostatic Hyperplasia Patients: A Pilot Study","volume":"4","author":"Hsieh","year":"2022","journal-title":"Pharmacol. Res.-Mod. Chin. Med."},{"key":"ref_132","doi-asserted-by":"crossref","unstructured":"Kusama, K., Miyagawa, M., Ota, K., Kuwabara, N., Saeki, K., Ohnishi, Y., Kumaki, Y., Aizawa, T., Nakasone, T., and Okamatsu, S. (2020). Cordyceps militaris Fruit Body Extract Decreases Testosterone Catabolism and Testosterone-Stimulated Prostate Hypertrophy. Nutrients, 13.","DOI":"10.3390\/nu13010050"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"1","DOI":"10.24018\/ejbiomed.2023.2.2.51","article-title":"The Administration of Cordyceps militaris Inhibited the Decrease of Leydig Cell Number and Testosterone Level in Male Wistar Rats (Rattus norvegicus) Exposed with Cigarette Smoke","volume":"2","author":"Salim","year":"2023","journal-title":"Eur. J. Biomed. Res."},{"key":"ref_134","doi-asserted-by":"crossref","unstructured":"Kopalli, S.R., Cha, K.-M., Lee, S.-H., Hwang, S.-Y., Lee, Y.-J., Koppula, S., and Kim, S.-K. (2019). Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom Cordyceps militaris Linn., Ameliorates Age-Related Testicular Dysfunction in Rats. Nutrients, 11.","DOI":"10.3390\/nu11040906"},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1007\/s00204-019-02490-x","article-title":"Ecdysteroids as Non-Conventional Anabolic Agent: Performance Enhancement by Ecdysterone Supplementation in Humans","volume":"93","author":"Isenmann","year":"2019","journal-title":"Arch. Toxicol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"e14001","DOI":"10.1111\/and.14001","article-title":"The Effect of Eurycoma longifolia on the Regulation of Reproductive Hormones in Young Males","volume":"53","author":"Chan","year":"2021","journal-title":"Andrologia"},{"key":"ref_137","first-page":"27","article-title":"Safety and Efficacy of Furosap\u00ae, a Patented Trigonella foenum-graecum Seed Extract, in Boosting Testosterone Level, Reproductive Health and Mood Alleviation in Male Volunteers","volume":"42","author":"Sankhwar","year":"2023","journal-title":"J. Am. Nutr. Assoc."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1002\/ptr.3360","article-title":"Physiological Aspects of Male Libido Enhanced by Standardized Trigonella foenum-graecum Extract and Mineral Formulation","volume":"25","author":"Steels","year":"2011","journal-title":"Phytother. Res."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"189","DOI":"10.5114\/biolsport.2025.150047","article-title":"\u201eBrain Doping\u201d Substances: Prohibited or Not in Sports?","volume":"42","author":"Pokrywka","year":"2025","journal-title":"Biol. Sport"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"108448","DOI":"10.1016\/j.biotechadv.2024.108448","article-title":"The Biosynthesis of L-Phenylalanine-Derived Compounds by Engineered Microbes","volume":"77","author":"Qiu","year":"2024","journal-title":"Biotechnol. Adv."},{"key":"ref_141","doi-asserted-by":"crossref","unstructured":"Surguchov, A. (2020). Role of Phenylalanine and Its Metabolites in Health and Neurological Disorders. Synucleins: Biochemistry and Role in Disease, IntechOpen.","DOI":"10.5772\/intechopen.73750"},{"key":"ref_142","unstructured":"National Center for Biotechnology Information (2025, November 16). PubChem Compound Summary for CID 6140, L-Phenylalanine, Available online: https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/L-Phenylalanine."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s12970-017-0191-x","article-title":"The Effects of Phenylalanine on Exercise-Induced Fat Oxidation: A Preliminary, Double-Blind, Placebo-Controlled, Crossover Trial","volume":"14","author":"Ueda","year":"2017","journal-title":"J. Int. Soc. 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