{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T02:42:44Z","timestamp":1787971364305,"version":"build-2784847793"},"reference-count":56,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Malnutrition and sarcopenia are highly prevalent in intensive care settings and are associated with adverse clinical outcomes. Aim: The study aimed to evaluate the association between nutritional care, nutritional status, and patient outcomes in intensive care units. Methods: This prospective observational study at a Tunisian tertiary hospital investigated nutritional status and management of 100 intensive care unit patients, each of whom was followed for seven days after ICU admission. Malnutrition Risk was assessed by NUTRIC and MNA scores. The severity of disease was assessed using the APACHE II and SOFA scores. Malnutrition was diagnosed using body mass index and weight loss. Sarcopenia was assessed through grip strength, calf circumference, and psoas muscle area. Nutritional management was evaluated using calculations of caloric and protein intake. Clinical outcomes included the need for intubation, difficulty with oxygen weaning, healthcare-associated infections, and the development of pressure ulcers. Results: The participants had a mean age of 54.85 \u00b1 17.25 years, with a slight male predominance (53 males, 47 females). Pre-existing metabolic conditions affected 80% of patients, including hypertension (40 patients), diabetes (36), and obesity (18). The primary reasons for admission were respiratory disorders (25%), infectious diseases (23%), and metabolic disorders (16%). The mean APACHE II score was 15.91 \u00b1 6.84, and the mean NUTRIC score was 3 \u00b1 1.66; 27% were classified as at high risk of malnutrition. The prevalence of malnutrition reached 50% (28% moderate, 22% severe). Only 31% received adequate caloric intake, while 84% had insufficient protein intake. Malnourished patients required intubation more frequently (50% versus 22.5%; p = 0.014), experienced greater difficulty with oxygen weaning (78.4% versus 48.6%; p = 0.008), and developed pressure ulcers more often (43.5% versus 6%; p &lt; 0.001). Sarcopenic patients showed similar patterns for intubation (51.4% versus 18.9%, p = 0.003), oxygen weaning difficulty (77.5% versus 46.9%, p = 0.007), and pressure ulcers (39.2% versus 6.7%, p &lt; 0.001). Conclusions: Malnutrition and sarcopenia are highly prevalent in intensive care patients and are associated with severe complications, including prolonged mechanical ventilation and pressure ulcer development. Inadequate nutritional support remains common despite known consequences. Early comprehensive nutritional assessment and appropriate management from admission are essential to improve outcomes in critically ill patients.<\/jats:p>","DOI":"10.3390\/nu18060883","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T17:04:24Z","timestamp":1773162264000},"page":"883","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["High Prevalence of Malnutrition and Sarcopenia with Inadequate Nutritional Support in Intensive Care Unit Patients: A Prospective Observational Study of Clinical Outcomes"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2453-9778","authenticated-orcid":false,"given":"Rym","family":"Ben Othman","sequence":"first","affiliation":[{"name":"Research Unit on Obesity UR18ES01, Faculty of Medicine, University of Tunis El Manar, 15 Rue Jebel Lakhdar, Beb Saadoun, Tunis 1007, Tunisia"},{"name":"Faculty of Medicine Tunis, University of Tunis el Manar, 11 Rue Jebel Lakhdar, Beb Saadoun, Tunis 1007, Tunisia"},{"name":"National Institute of Nutrition and Food Technology of Tunis, 11 Jbal Lakhdar Street, Tunis 1007, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Cherni","sequence":"additional","affiliation":[{"name":"National Institute of Nutrition and Food Technology of Tunis, 11 Jbal Lakhdar Street, Tunis 1007, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8091-1856","authenticated-orcid":false,"given":"Ismail","family":"Dergaa","sequence":"additional","affiliation":[{"name":"Higher Institute of Sport and Physical Education of Ksar Sa\u00efd, University of Manouba, Manouba 2010, Tunisia"},{"name":"Physical Activity Research Unit, Sport and Health (UR18JS01), National Observatory of Sports, Tunis 1003, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2214-4667","authenticated-orcid":false,"given":"Halil \u0130brahim","family":"Ceylan","sequence":"additional","affiliation":[{"name":"Department of Physical Education of Sports Teaching, Faculty of Sports Sciences, Atat\u00fcrk University, Erzurum 25240, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagihan Bur\u00e7ak","family":"Ceylan","sequence":"additional","affiliation":[{"name":"Graduate Education Institute, Bayburt University, Bayburt 69000, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4031-1412","authenticated-orcid":false,"given":"Valentina","family":"Stefanica","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport, Faculty of Sciences, Physical Education and Informatics, National University of Science and Technology Politehnica Bucharest, 060042 Pite\u0219ti, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Sedghiani","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Hbib Thameur Hospital, Tunis 1008, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nebiha","family":"Borsali","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Hbib Thameur Hospital, Tunis 1008, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8215-3718","authenticated-orcid":false,"given":"Henda","family":"Jamoussi","sequence":"additional","affiliation":[{"name":"Research Unit on Obesity UR18ES01, Faculty of Medicine, University of Tunis El Manar, 15 Rue Jebel Lakhdar, Beb Saadoun, Tunis 1007, Tunisia"},{"name":"Faculty of Medicine Tunis, University of Tunis el Manar, 11 Rue Jebel Lakhdar, Beb Saadoun, Tunis 1007, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.reaurg.2010.06.009","article-title":"Physiopathologie de La D\u00e9nutrition En R\u00e9animation","volume":"19","author":"Souweine","year":"2010","journal-title":"R\u00e9animation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.clnu.2018.08.037","article-title":"ESPEN Guideline on Clinical Nutrition in the Intensive Care Unit","volume":"38","author":"Singer","year":"2019","journal-title":"Clin. 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