{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T15:06:02Z","timestamp":1773414362119,"version":"3.50.1"},"reference-count":42,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: Patients with food allergy (FA) may exhibit dysfunctional eating behaviours and\/or food aversions that extend beyond the necessary allergen elimination diet and may result in avoidant\/restrictive food intake disorder (ARFID) or food neophobia (FN); however, no data are available on adults. This study aimed to explore ARFID, FN, FA anxiety, and eating styles in adults with FA, analysing influences of sociodemographic and clinical factors. Methods: This cross-sectional preliminary study involved 79 adults with FA, who completed the Nine Item ARFID screen (NIAS), Food Neophobia Scale (FNS), Scale of Food Allergy Anxiety (SOFAA), and Dutch Eating Behaviour Questionnaire (DEBQ\u2014brief). Pearson and Spearman correlation coefficients and multiple linear regressions were performed (p &lt; 0.05). Results: In total, 25% and 73% of participants scored positively for ARFID and FN, respectively. A positive correlation was observed between FN and ARFID levels (p &lt; 0.006), and between FN and FA anxiety (p &lt; 0.001). Current psychological problems positively correlated with ARFID (p = 0.004), FN (p = 0.006), and FA anxiety scores (p = 0.03). Restrained eating was positively associated with female gender (p &lt; 0.001), and ARFID (p = 0.002) and FN scores (p = 0.028). External eating was negatively correlated with ARFID (p = 0.004). Adrenaline auto-injector (AAI) prescription was negatively associated with ARFID (p &lt; 001) and restrained eating (p = 0.006), while previous anaphylaxis was negatively associated with ARFID (p = 0.020) and positively associated with external eating (p = 0.021). Multiple logistic regression models confirmed that restrained eating was associated with a higher probability of both ARFID (p = 0.031) and FN (p = 0.074). Conclusions: Clinicians should be aware of the risk of ARFID and FN among adult patients with FA and recommend appropriate psychological and dietary support. Further studies are needed to better understand the protective and precipitating factors of ARFID and FN to develop effective prevention and treatment strategies.<\/jats:p>","DOI":"10.3390\/nu18060913","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T11:12:25Z","timestamp":1773400345000},"page":"913","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Avoidant\/Restrictive Food Intake Disorder and Food Neophobia in Adult Patients with Food Allergy: A Preliminary Study"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0158-359X","authenticated-orcid":false,"given":"Laura","family":"Polloni","sequence":"first","affiliation":[{"name":"Food Allergy Referral Centre, Veneto Region, Department of Women\u2019s and Children\u2019s Health, Padua University Hospital, 35128 Padua, Italy"},{"name":"Unit of Psychology, Padua University Hospital, 35128 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2360-9965","authenticated-orcid":false,"given":"Lucia","family":"Ronconi","sequence":"additional","affiliation":[{"name":"Computer and Statistical Services, Multifunctional Pole of Psychology, University of Padua, 35100 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"De Fazio","sequence":"additional","affiliation":[{"name":"Unit of Psychology, Padua University Hospital, 35128 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Bonaguro","sequence":"additional","affiliation":[{"name":"Food Allergy Referral Centre, Veneto Region, Department of Women\u2019s and Children\u2019s Health, Padua University Hospital, 35128 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Lazzarotto","sequence":"additional","affiliation":[{"name":"Food Allergy Referral Centre, Veneto Region, Department of Women\u2019s and Children\u2019s Health, Padua University Hospital, 35128 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Toniolo","sequence":"additional","affiliation":[{"name":"Food Allergy Referral Centre, Veneto Region, Department of Women\u2019s and Children\u2019s Health, Padua University Hospital, 35128 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossana","family":"Schiavo","sequence":"additional","affiliation":[{"name":"Unit of Psychology, Padua University Hospital, 35128 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Muraro","sequence":"additional","affiliation":[{"name":"Food Allergy Referral Centre, Veneto Region, Department of Women\u2019s and Children\u2019s Health, Padua University Hospital, 35128 Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/all.16345","article-title":"EAACI guidelines on the management of IgE-mediated food allergy","volume":"80","author":"Santos","year":"2025","journal-title":"Allergy"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e12078","DOI":"10.1002\/clt2.12078","article-title":"Psychological needs and support among patients and families undergoing food oral immunotherapy","volume":"12","author":"Polloni","year":"2022","journal-title":"Clin. Transl. Allergy"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/all.13319","article-title":"EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy","volume":"73","author":"Pajno","year":"2018","journal-title":"Allergy"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"100891","DOI":"10.1016\/j.waojou.2024.100891","article-title":"The mental health burden of food allergies: Insights from patients and their caregivers from the Food Allergy Research & Education (FARE) Patient Registry","volume":"17","author":"Casale","year":"2024","journal-title":"World Allergy Organ. J."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Di Cesare, G., Carciofi, A., Borgiani, F., Cappelletti, D., Correani, A., Monachesi, C., and Lionetti, M.E. (2025). Are We Meeting the Needs? A Systematic Review of Nutritional Gaps and Growth Outcomes in Children with Multiple Food Allergies. Nutrients, 17.","DOI":"10.3390\/nu17091590"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s12016-018-8708-x","article-title":"Beyond Avoidance: The Psychosocial Impact of Food Allergies","volume":"57","author":"Feng","year":"2019","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.jaip.2021.07.052","article-title":"Avoidant-restrictive food intake disorder (ARFID): A treatable complication of food allergy","volume":"10","author":"Patrawala","year":"2022","journal-title":"J. Allergy Clin. Immunol. Pract."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1016\/j.jaip.2023.04.010","article-title":"Systematic Review of the Incidence and\/or Prevalence of Eating Disorders in Individuals With Food Allergies","volume":"11","author":"Ciciulla","year":"2023","journal-title":"J. Allergy Clin. Immunol. Pract."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders, American Psychiatric Association.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1176\/appi.focus.20240008","article-title":"Avoidant\/Restrictive Food Intake Disorder: Review and Recent Advances","volume":"22","author":"Menzel","year":"2024","journal-title":"Focus"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Bia\u0142ek-Dratwa, A., Szczepa\u0144ska, E., Szyma\u0144ska, D., Grajek, M., Krupa-Kotara, K., and Kowalski, O. (2022). Neophobia\u2014A Natural Developmental Stage or Feeding Difficulties for Children?. Nutrients, 14.","DOI":"10.3390\/nu14071521"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1002\/eat.23520","article-title":"Validation of the nine item ARFID screen (NIAS) subscales for distinguishing ARFID presentations and screening for ARFID","volume":"54","author":"Murray","year":"2021","journal-title":"Int. J. Eat. Disord."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Bia\u0142ek-Dratwa, A., Sta\u015bkiewicz-Bartecka, W., Kiciak, A., Wardyniec, A., Grajek, M., Akta\u00e7, \u015e., and Kowalski, O. (2024). Food Neophobia and Avoidant\/Restrictive Food Intake among Adults and Related Factors. Nutrients, 16.","DOI":"10.3390\/nu16172952"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e70187","DOI":"10.1111\/pai.70187","article-title":"Food-induced anaphylaxis and mental health in children and their parents: A narrative review","volume":"36","author":"Polloni","year":"2025","journal-title":"Pediatr. Allergy Immunol."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Nocerino, R., Mercuri, C., Bosco, V., Giordano, V., Simeone, S., Guillari, A., and Rea, T. (2024). Development and Management of Avoidant\/Restrictive Food Intake Disorder and Food Neophobia in Pediatric Patients with Food Allergy: A Comprehensive Review. Nutrients, 16.","DOI":"10.3390\/nu16173034"},{"key":"ref_16","first-page":"81","article-title":"Psychological and Sociological Influences Contributing to Avoidant Restrictive Food Intake Disorder (ARFID) Across Age Groups and Gender","volume":"1","author":"Kerna","year":"2024","journal-title":"Eur. J. Arts Humanit. Soc. Sci."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/cea.13548","article-title":"Anxiety and food allergy: A review of the last two decades","volume":"50","author":"Polloni","year":"2020","journal-title":"Clin. Exp. Allergy"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jaip.2021.06.039","article-title":"Development of the Child- and Parent-Rated Scales of Food Allergy Anxiety (SOFAA)","volume":"10","author":"Dahlsgaard","year":"2021","journal-title":"J. Allergy Clin. Immunol. Pract."},{"key":"ref_19","first-page":"100197","article-title":"Food Allergy, Eating Disorders and Body Image","volume":"6","author":"Jafri","year":"2022","journal-title":"J. Affect. Disord. Rep."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"e14119","DOI":"10.1111\/pai.14119","article-title":"Feeding difficulties in children with food allergies: An EAACI Task Force Report","volume":"35","author":"Hill","year":"2024","journal-title":"Pediatr. Allergy Immunol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"150","DOI":"10.5114\/pedm.2019.87711","article-title":"Food neophobia in children Neofobia \u017cywieniowa u dzieci","volume":"25","author":"Januszewicz","year":"2019","journal-title":"Pediatr. Endocrinol. Diabetes Metab."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.appet.2017.11.111","article-title":"Initial validation of the Nine Item Avoidant\/Restrictive Food Intake disorder screen (NIAS): A measure of three restrictive eating patterns","volume":"123","author":"Zickgraf","year":"2018","journal-title":"Appetite"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0195-6663(92)90014-W","article-title":"Development of a scale to measure the trait of food neophobia in humans","volume":"19","author":"Pliner","year":"1992","journal-title":"Appetite"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.foodqual.2018.02.007","article-title":"Associations between food neophobia and responsiveness to \u201cwarning\u201d chemosensory sensations in food products in a large population sample","volume":"68","author":"Laureati","year":"2018","journal-title":"Food Qual. Prefer."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Vanaken, L., Scheveneels, S., Belmans, E., and Hermans, D. (2020). Validation of the Impact of Event Scale With Modifications for COVID-19 (IES-COVID19). Front. Psychiatry, 11.","DOI":"10.3389\/fpsyt.2020.00738"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.appet.2013.08.010","article-title":"Italian version of the Dutch Eating Behavior Questionnaire. Psychometric proprieties and measurement invariance across sex, BMI-status and age","volume":"71","author":"Dakanalis","year":"2013","journal-title":"Appetite"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Jezewska-Zychowicz, M., Plichta, M., Drywie\u0144, M.E., and Hamulka, J. (2021). Food Neophobia among Adults: Differences in Dietary Patterns, Food Choice Motives, and Food Labels Reading in Poles. Nutrients, 13.","DOI":"10.3390\/nu13051590"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Bugi, M.-A., Jug\u0103naru, I., Simina, I.-E., Nicoar\u0103, D.-M., Cristun, L.-I., Brad, G.-F., Boru, C., C\u00eernatu, D., and M\u0103rginean, O. (2024). Exploring Adult Eating Behaviors and Food Neophobia: A National Study in Romania. Foods, 13.","DOI":"10.3390\/foods13091301"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Predieri, S., Sinesio, F., Monteleone, E., Spinelli, S., Cianciabella, M., Daniele, G.M., Dinnella, C., Gasperi, F., Endrizzi, I., and Torri, L. (2020). Gender, Age, Geographical Area, Food Neophobia and Their Relationships with the Adherence to the Mediterranean Diet: New Insights from a Large Population Cross-Sectional Study. Nutrients, 12.","DOI":"10.3390\/nu12061778"},{"key":"ref_30","first-page":"1","article-title":"Perception of typical Ukrainian foods among an Italian population","volume":"25","author":"Bignami","year":"2012","journal-title":"Food Qual. Preference"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"102502","DOI":"10.1016\/j.cpr.2024.102502","article-title":"Avoidant\/restrictive food intake disorder: Systematic review and meta-analysis demonstrating the impact of study quality on prevalence rates","volume":"114","author":"Waller","year":"2024","journal-title":"Clin. Psychol. Rev."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s40337-017-0149-z","article-title":"Burden and health-related quality of life of eating disorders, including Avoidant\/Restrictive Food Intake Disorder (ARFID), in the Australian population","volume":"5","author":"Hay","year":"2017","journal-title":"J. Eat. Disord."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.eatbeh.2016.12.004","article-title":"Clinical presentation and outcome of avoidant\/restrictive food intake disorder in a Japanese sample","volume":"24","author":"Nakai","year":"2017","journal-title":"Eat. Behav."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/s40337-023-00939-0","article-title":"Prevalence, characteristics, and correlates of probable avoidant\/restrictive food intake disorder among adult respondents to the National Eating Disorders Association online screen: A cross-sectional study","volume":"11","author":"Smolar","year":"2023","journal-title":"J. Eat. Disord."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Proctor, K.B., Vickery, B.P., and Sharp, W.G. (Int. J. Eat. Disord., 2026). When Medically Required Food Avoidance Goes Awry: A Conceptual Framework of ARFID as an Underrecognized Clinical Complication of Food Allergy, Int. J. Eat. Disord., online ahead of print.","DOI":"10.1002\/eat.70049"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/eat.24588","article-title":"The Prevalence and Burden of Avoidant\/Restrictive Food Intake Disorder ( ARFID ) Symptoms in the Adult General Population of the UK and USA","volume":"59","author":"Brownlow","year":"2025","journal-title":"Int. J. Eat. Disord."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1111\/all.13055","article-title":"Assessment of children\u2019s nutritional attitudes before oral food challenges to identify patients at risk of food reintroduction failure: A prospective study","volume":"72","author":"Polloni","year":"2017","journal-title":"Allergy"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1111\/all.16204","article-title":"Global availability and uptake of psychological services for adults, caregivers and children with food allergy","volume":"79","author":"Knibb","year":"2024","journal-title":"Allergy"},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Nocerino, R., Mercuri, C., Bosco, V., Aquilone, G., Guillari, A., Simeone, S., and Rea, T. (2024). Food Allergy-Related Bullying in Pediatric Patients: A Systematic Review. Children, 11.","DOI":"10.3390\/children11121485"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.jaip.2024.09.036","article-title":"Food allergy, nutrition, psychology, and health","volume":"13","author":"Gupta","year":"2024","journal-title":"J. Allergy Clin. Immunol. Pract."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"7010","DOI":"10.1038\/s41598-023-34113-y","article-title":"Alteration of taste perception, food neophobia and oral microbiota composition in children with food allergy","volume":"13","author":"Cattaneo","year":"2023","journal-title":"Sci. Rep."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Santos, A.F., Worm, M., Kurita, S., Wong, T., Contato, D., Pirillo, E., Esteban, A.E., Tassinari, P., Perna, F., and Chinthrajah, R.S. (2023). Living with food allergies: The experiences of adult patients and caregivers. Front. Allergy, 4.","DOI":"10.3389\/falgy.2023.1272851"}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/18\/6\/913\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T11:20:17Z","timestamp":1773400817000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/18\/6\/913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,13]]},"references-count":42,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,3]]}},"alternative-id":["nu18060913"],"URL":"https:\/\/doi.org\/10.3390\/nu18060913","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,13]]}}}