{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T01:35:50Z","timestamp":1782869750602,"version":"3.54.5"},"reference-count":56,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Structural and Investment Funds","award":["#KK.01.1.1.01.0010"],"award-info":[{"award-number":["#KK.01.1.1.01.0010"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: This study investigated the effect of the consumption of carnosine-enriched chicken meat on endothelium-dependent and independent microvascular reactivity and inflammatory mediators in patients with chronic coronary syndrome (CCS). Materials and Methods: In total, 38 CCS participants were randomized to two groups: the Control group (N = 19), who consumed regular chicken meat, and the Carnosine group (N = 19), who consumed carnosine-enriched chicken meat for 3 weeks. Skin microvascular reactivity in response to vascular occlusion (PORH), acetylcholine (ACh ID), sodium nitroprusside (SNP ID), and local thermal hyperemia (LTH) was measured. Arterial blood pressure (BP), heart rate (HR), biochemical parameters, anti- and proinflammatory cytokine levels, and markers of oxidative stress were assessed before and after the intervention. Results: The consumption of carnosine-enriched chicken meat improved endothelium-dependent (PORH, LTH) and endothelium-independent vasodilation (SNP ID). Systolic BP (SBP), diastolic BP (DBP), and mean BP (MAP), as well as serum concentrations of tumor necrosis factor-alpha (TNF-\u03b1), interleukin-6 (IL-6), and endoglin, decreased from the initial measurements. Conclusion: The consumption of carnosine-enriched chicken meat enhances microvascular endothelium-dependent and independent vasodilatation. Patients with CCS can benefit from carnosine-enriched chicken meat consumption through improved hemodynamic parameters, reduced inflammation, and enhanced microvascular relaxation.<\/jats:p>","DOI":"10.3390\/nu18060928","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T13:32:07Z","timestamp":1773667927000},"page":"928","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Carnosine-Enriched Chicken Meat Improves Microvascular Function and Anti-Inflammatory Phenotype in Patients with Chronic Coronary Syndrome"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9063-1433","authenticated-orcid":false,"given":"Dora","family":"Ur\u0161i\u0107","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Clinical Immunology and Allergology, University Hospital Center Osijek, 31000Osijek, Croatia"},{"name":"Department of Internal Medicine and History of Medicine, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"},{"name":"Scientific Centre of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5649-8317","authenticated-orcid":false,"given":"Nikolina","family":"Kolobari\u0107","sequence":"additional","affiliation":[{"name":"Scientific Centre of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"},{"name":"Department of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4964-7721","authenticated-orcid":false,"given":"Ines","family":"Drenjan\u010devi\u0107","sequence":"additional","affiliation":[{"name":"Scientific Centre of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"},{"name":"Department of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6631-071X","authenticated-orcid":false,"given":"Zrinka","family":"Mihaljevi\u0107","sequence":"additional","affiliation":[{"name":"Scientific Centre of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"},{"name":"Department of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petar","family":"\u0160u\u0161njara","sequence":"additional","affiliation":[{"name":"Scientific Centre of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"},{"name":"Department of Interdisciplinary Sciences, Faculty of Kinesiology Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7446-0021","authenticated-orcid":false,"given":"Ana","family":"Stupin","sequence":"additional","affiliation":[{"name":"Scientific Centre of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"},{"name":"Department of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3795-2112","authenticated-orcid":false,"given":"Ivana","family":"Juki\u0107","sequence":"additional","affiliation":[{"name":"Scientific Centre of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"},{"name":"Department of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7843-1079","authenticated-orcid":false,"given":"Aleksandar","family":"Kibel","sequence":"additional","affiliation":[{"name":"Scientific Centre of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"},{"name":"Department of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"},{"name":"Scientific Unit for Medical Research, International Medical Center Priora, 31431 Cepin, Croatia"},{"name":"Department of Clinical Medicine, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.2174\/0929867326666190712091515","article-title":"Inflammation as the Common Biological Link Between Depression and Cardiovascular Diseases: Can Carnosine Exert a Protective Role?","volume":"27","author":"Caruso","year":"2020","journal-title":"Curr. Med. Chem."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"III-27","DOI":"10.1161\/01.CIR.0000131515.03336.f8","article-title":"Role of endothelial dysfunction in atherosclerosis","volume":"109","author":"Davignon","year":"2004","journal-title":"Circulation"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1161\/CIRCRESAHA.115.306301","article-title":"Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis","volume":"118","author":"Gimbrone","year":"2016","journal-title":"Circ. Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur. Heart J."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"107230","DOI":"10.1016\/j.vph.2023.107230","article-title":"Hypertension, coronary artery disease and myocardial ischemic syndromes","volume":"153","author":"Volpe","year":"2023","journal-title":"Vasc. Pharmacol."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Gallo, G., Volpe, M., and Savoia, C. (2021). Endothelial Dysfunction in Hypertension: Current Concepts and Clinical Implications. Front. Med., 8.","DOI":"10.3389\/fmed.2021.798958"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1152\/physrev.00039.2012","article-title":"Physiology and pathophysiology of carnosine","volume":"93","author":"Boldyrev","year":"2013","journal-title":"Physiol. Rev."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1136\/gut.16.8.585","article-title":"Carnosinase activity of human gastrointestinal mucosa","volume":"16","author":"Sadikali","year":"1975","journal-title":"Gut"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.mam.2011.10.009","article-title":"Neuroprotective features of carnosine in oxidative driven diseases","volume":"32","author":"Bellia","year":"2011","journal-title":"Mol. Asp. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"8","DOI":"10.31665\/JFB.2019.5174","article-title":"Carnosine\u2014A natural bioactive dipeptide: Bioaccessibility, bioavailability and health benefits","volume":"5","author":"Xing","year":"2019","journal-title":"J. Food Bioact."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/chir.22056","article-title":"Predicting the physicochemical profile of diastereoisomeric histidine-containing dipeptides by property space analysis","volume":"24","author":"Vistoli","year":"2012","journal-title":"Chirality"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S1043-4526(09)57003-9","article-title":"Carnosine and its possible roles in nutrition and health","volume":"57","author":"Hipkiss","year":"2009","journal-title":"Adv. Food Nutr. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1007\/s00726-018-2592-9","article-title":"Carnosine and advanced glycation end products: A systematic review","volume":"50","author":"Ghodsi","year":"2018","journal-title":"Amino Acids"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"421","DOI":"10.4162\/nrp.2011.5.5.421","article-title":"Effects of \u03b1-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats","volume":"5","author":"Kim","year":"2011","journal-title":"Nutr. Res. Pr."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/iep.12252","article-title":"Carnosine decreased oxidation and glycation products in serum and liver of high-fat diet and low-dose streptozotocin-induced diabetic rats","volume":"98","author":"Uysal","year":"2017","journal-title":"Int. J. Exp. Pathol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"190","DOI":"10.18047\/poljo.21.1.sup.45","article-title":"Effect of \u03b2-alanine and L-histidine on concentration of carnosine in muscle tissue and oxidative stability of chicken meat","volume":"21","author":"Kralik","year":"2015","journal-title":"Poljoprivreda"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1111\/j.1582-4934.2010.01101.x","article-title":"The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats","volume":"15","author":"Aldini","year":"2011","journal-title":"J. Cell. Mol. Med."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ejphar.2005.02.010","article-title":"Histidine and carnosine delay diabetic deterioration in mice and protect human low density lipoprotein against oxidation and glycation","volume":"513","author":"Lee","year":"2005","journal-title":"Eur. J. Pharmacol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1177\/0960327115597468","article-title":"Beneficial effects of carnosine and carnosine plus vitamin E treatments on doxorubicin-induced oxidative stress and cardiac, hepatic, and renal toxicity in rats","volume":"35","author":"Kumral","year":"2016","journal-title":"Hum. Exp. Toxicol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.nut.2014.04.021","article-title":"Effects of oral administration of orodispersible levo-carnosine on quality of life and exercise performance in patients with chronic heart failure","volume":"31","author":"Lombardi","year":"2015","journal-title":"Nutrition"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Juki\u0107, I., Kolobari\u0107, N., Stupin, A., Mati\u0107, A., Kozina, N., Mihaljevi\u0107, Z., Mihalj, M., \u0160u\u0161njara, P., Stupin, M., and \u0106uri\u0107, \u017d.B. (2021). Carnosine, Small but Mighty-Prospect of Use as Functional Ingredient for Functional Food Formulation. Antioxidants, 10.","DOI":"10.3390\/antiox10071037"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"3415","DOI":"10.1093\/eurheartj\/ehae177","article-title":"2024 ESC Guidelines for the management of chronic coronary syndromes","volume":"45","author":"Vrints","year":"2024","journal-title":"Eur. Heart J."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"239","DOI":"10.2141\/jpsa.0170083","article-title":"Effect of Amino Acids on Growth Performance, Carcass Characteristics, Meat Quality, and Carnosine Concentration in Broiler Chickens","volume":"55","author":"Kralik","year":"2018","journal-title":"J. Poult. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Kolobari\u0107, N., Peri\u0107, L., Mihaljevi\u0107, Z., \u0160u\u0161njara, P., Boris, A., Drenjan\u010devi\u0107, I., Juki\u0107, I., and Stupin, A. (2025). Antioxidant Effects of Carnosine-Enriched Chicken Meat Consumption in Athletes: Modulation of SOD Activity and Superoxide Levels-A Randomized Control Trial. Antioxidants, 14.","DOI":"10.3390\/antiox14091069"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Kolobari\u0107, N., Gradinjan Centner, M., \u0160u\u0161njara, P., Mati\u0107, A., and Drenjan\u010devi\u0107, I. (2020). Anthropometric and Biochemical Parameters in Relation to Dietary Habits as Early Indicator of Cardiovascular Impairment in Young Adult Cohort. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17249208"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"5313","DOI":"10.1113\/JP271631","article-title":"The role of cyclo-oxygenase-1 in high-salt diet-induced microvascular dysfunction in humans","volume":"593","author":"Cavka","year":"2015","journal-title":"J. Physiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1139\/apnm-2017-0735","article-title":"Omega-3 polyunsaturated fatty acids-enriched hen eggs consumption enhances microvascular reactivity in young healthy individuals","volume":"43","author":"Stupin","year":"2018","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.tips.2006.07.008","article-title":"Methodological issues in the assessment of skin microvascular endothelial function in humans","volume":"27","author":"Cracowski","year":"2006","journal-title":"Trends Pharmacol. Sci."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0166-445X(02)00204-7","article-title":"Utility of the TBARS assay in detecting oxidative stress in white sucker (Catostomus commersoni) populations exposed to pulp mill effluent","volume":"63","author":"Oakes","year":"2003","journal-title":"Aquat. Toxicol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1006\/abio.1996.0292","article-title":"The ferric reducing ability of plasma (FRAP) as a measure of \u201cantioxidant power\u201d: The FRAP assay","volume":"239","author":"Benzie","year":"1996","journal-title":"Anal. Biochem."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S1566-0702(02)00048-6","article-title":"Effects of L-carnosine on renal sympathetic nerve activity and DOCA-salt hypertension in rats","volume":"97","author":"Niijima","year":"2002","journal-title":"Auton. Neurosci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"116905","DOI":"10.1016\/j.lfs.2019.116905","article-title":"The effects of l-Carnosine on development of metabolic syndrome in rats","volume":"237","author":"Alshogran","year":"2019","journal-title":"Life Sci."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0014-2999(84)90434-5","article-title":"Enhanced carnosine (beta-alanyl-L-histidine) breakdown and histamine metabolism following treatment with compound 48\/80","volume":"99","author":"Greene","year":"1984","journal-title":"Eur. J. Pharmacol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S0899-9007(99)00268-3","article-title":"Vasodilatory actions of the dietary peptide carnosine","volume":"16","author":"Ririe","year":"2000","journal-title":"Nutrition"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ejphar.2010.12.001","article-title":"Histidine and carnosine alleviated hepatic steatosis in mice consumed high saturated fat diet","volume":"653","author":"Mong","year":"2011","journal-title":"Eur. J. Pharmacol."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Saadati, S., Cameron, J., Menon, K., Hodge, A., Lu, Z.X., de Courten, M., Feehan, J., and de Courten, B. (2023). Carnosine Did Not Affect Vascular and Metabolic Outcomes in Patients with Prediabetes and Type 2 Diabetes: A 14-Week Randomized Controlled Trial. Nutrients, 15.","DOI":"10.3390\/nu15224835"},{"key":"ref_37","first-page":"1","article-title":"Carnosine-enriched functional food enhances micro- and macrovascular endothelium-independent vasodilation in competitive athletes-a randomized study","volume":"50","author":"Boris","year":"2025","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.archger.2014.04.008","article-title":"Anserine and carnosine supplementation in the elderly: Effects on cognitive functioning and physical capacity","volume":"59","author":"Rymaszewska","year":"2014","journal-title":"Arch. Gerontol. Geriatr."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"399","DOI":"10.12659\/MSM.890528","article-title":"L-carnosine alters some hemorheologic and lipid peroxidation parameters in nephrectomized rats","volume":"20","author":"Yapislar","year":"2014","journal-title":"Med. Sci. Monit."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"887","DOI":"10.3390\/nu7020887","article-title":"The effect of chicken extract on mood, cognition and heart rate variability","volume":"7","author":"Young","year":"2015","journal-title":"Nutrients"},{"key":"ref_41","first-page":"H462","article-title":"Carnosine is a novel peptide modulator of intracellular calcium and contractility in cardiac cells","volume":"272","author":"Zaloga","year":"1997","journal-title":"Am. J. Physiol."},{"key":"ref_42","first-page":"1389","article-title":"The protective effect of carnosine in hypoxia and reoxygenation of the isolated rat heart","volume":"57","author":"Laptev","year":"1992","journal-title":"Biokhimiia"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1055\/s-0043-100117","article-title":"Effect of Carnosine on Renal Function, Oxidation and Glycation Products in the Kidneys of High-Fat Diet\/Streptozotocin-Induced Diabetic Rats","volume":"125","author":"Uysal","year":"2017","journal-title":"Exp. Clin. Endocrinol. Diabetes"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1113\/jphysiol.1996.sp021613","article-title":"The dipeptide carnosine constricts rabbit saphenous vein as a zinc complex apparently via a serotonergic receptor","volume":"495","author":"Miller","year":"1996","journal-title":"J. Physiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1248\/bpb.32.1836","article-title":"Carnosine facilitates nitric oxide production in endothelial f-2 cells","volume":"32","author":"Takahashi","year":"2009","journal-title":"Biol. Pharm. Bull."},{"key":"ref_46","first-page":"783","article-title":"Carnosine as a regulator of soluble guanylate cyclase","volume":"65","author":"Severina","year":"2000","journal-title":"Biochemistry"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"10","DOI":"10.2174\/1871530317666170703123519","article-title":"Carnosine Treatment Diminished Oxidative Stress and Glycation Products in Serum and Tissues of D-Galactose-Treated Rats","volume":"11","author":"Aydin","year":"2018","journal-title":"Curr. Aging Sci."},{"key":"ref_48","first-page":"9","article-title":"TNF-\u03b1 in the cardiovascular system: From physiology to therapy","volume":"7","author":"Urschel","year":"2015","journal-title":"Int. J. Interferon Cytokine Mediat. Res."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1182\/blood-2006-05-020875","article-title":"Tumor necrosis factor alpha (TNF-alpha) receptor-II is required for TNF-alpha-induced leukocyte-endothelial interaction in vivo","volume":"109","author":"Chandrasekharan","year":"2007","journal-title":"Blood"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1159\/000079706","article-title":"Role of JAK\/STAT pathway in IL-6-induced activation of vascular smooth muscle cells","volume":"24","author":"Watanabe","year":"2004","journal-title":"Am. J. Nephrol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1056\/NEJMra071014","article-title":"Platelet activation and atherothrombosis","volume":"357","author":"Patrono","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s11064-016-2104-9","article-title":"Carnosine Attenuates Brain Oxidative Stress and Apoptosis After Intracerebral Hemorrhage in Rats","volume":"42","author":"Xie","year":"2017","journal-title":"Neurochem. Res."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1093\/nutrit\/nuad150","article-title":"Effects of carnosine and histidine-containing dipeptides on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis","volume":"82","author":"Saadati","year":"2024","journal-title":"Nutr. Rev."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"6099","DOI":"10.1096\/fj.201802245R","article-title":"Regulation and role of endoglin in cholesterol-induced endothelial and vascular dysfunction in vivo and in vitro","volume":"33","author":"Vicen","year":"2019","journal-title":"FASEB J."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.atherosclerosis.2015.10.003","article-title":"Soluble endoglin, hypercholesterolemia and endothelial dysfunction","volume":"243","author":"Rathouska","year":"2015","journal-title":"Atherosclerosis"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.7150\/ijms.115222","article-title":"Soluble endoglin reflects endothelial dysfunction in myocardial infarction patients: A retrospective observational study","volume":"22","author":"Rathouska","year":"2025","journal-title":"Int. J. Med. Sci."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/18\/6\/928\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T13:39:57Z","timestamp":1773668397000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/18\/6\/928"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,15]]},"references-count":56,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,3]]}},"alternative-id":["nu18060928"],"URL":"https:\/\/doi.org\/10.3390\/nu18060928","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,15]]}}}