{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T09:59:36Z","timestamp":1785405576291,"version":"3.56.0"},"reference-count":58,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Science and Technology Major Project of China","award":["2024ZD0524500"],"award-info":[{"award-number":["2024ZD0524500"]}]},{"name":"National Science and Technology Major Project of China","award":["2024ZD0524502"],"award-info":[{"award-number":["2024ZD0524502"]}]},{"name":"Science Technology Project of Guangzhou Municipal Health Commission","award":["20251A011053"],"award-info":[{"award-number":["20251A011053"]}]},{"award":["20251A011053"],"award-info":[{"award-number":["20251A011053"]}],"id":[{"id":"https:\/\/ror.org\/044bb5p62","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Key Project of Medicine Discipline of Guangzhou","award":["2025-2027-12"],"award-info":[{"award-number":["2025-2027-12"]}]},{"name":"Science and Technology Plan Project of Guangzhou","award":["2024A03J0418"],"award-info":[{"award-number":["2024A03J0418"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Optimizing nutritional care for people with multimorbidity requires effective and feasible tools for early risk identification. This study aimed to investigate the associations of conicity index (C-index) and body roundness index (BRI) with multimorbidity among adults in Guangzhou, and to explore their potential utility in identifying individuals who may benefit from prioritized nutritional assessment. Methods: Based on the Fourth Adult Chronic Disease and Risk Factor Surveillance Program in Guangzhou, a total of 15,532 adults were recruited in this cross-sectional study. Multiple logistic regression analysis, restricted cubic spline (RCS) analysis and receiver operating characteristic curve (ROC) analysis with DeLong\u2019s test were performed. Results: The prevalence of multimorbidity was 38.95%. Higher C-index and BRI quartiles were significantly associated with increased multimorbidity risk. Compared with the lowest quartile, the adjusted OR for the highest C-index quartile was 1.98 (95% CI: 1.78\u20132.21), and for the highest BRI quartile it was 3.05 (95% CI: 2.74\u20133.41). A dose\u2013response relationship was observed (p &lt; 0.001). BRI showed statistically significantly higher discriminative ability relative to traditional anthropometric indices, though its overall discriminative performance was modest (AUC = 0.678). Conclusions: C-index and BRI are strongly and positively associated with multimorbidity. These simple, non-invasive indices may support community-based risk stratification and help identify individuals who warrant further clinical and nutritional assessment.<\/jats:p>","DOI":"10.3390\/nu18142286","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T08:53:58Z","timestamp":1783932838000},"page":"2286","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of Conicity Index and Body Roundness Index with Multimorbidity Among Adults in Guangzhou, China: A Cross-Sectional Study and Implications for Nutritional Risk Stratification"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6227-627X","authenticated-orcid":false,"given":"Jiamin","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Basic Public Health, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"},{"name":"Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Basic Public Health, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"},{"name":"Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0484-1715","authenticated-orcid":false,"given":"Weiquan","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Basic Public Health, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"},{"name":"Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liying","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Basic Public Health, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"},{"name":"Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minying","family":"Sun","sequence":"additional","affiliation":[{"name":"Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"},{"name":"Department of Science and Education Information, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaohui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Basic Public Health, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"},{"name":"Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"},{"name":"Department of Foodborne Diseases and Food Safety Risk Surveillance, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunou","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Basic Public Health, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"},{"name":"Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8924-0734","authenticated-orcid":false,"given":"Lei","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Health Management, Guangzhou Medical University, Guangzhou 510182, China"},{"name":"Social Science Key Laboratory of Guangdong Higher Education Institutes for Health Management Policy and Precision Health Services, Guangzhou 510515, China"},{"name":"Social Science Key Laboratory of Guangdong Higher Education Institutes for Health Governance Based on Big Data Utilization, Guangzhou 511436, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Basic Public Health, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"},{"name":"Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"ref_1","unstructured":"WHO (2008). The World Health Report 2008: Primary Health Cared Now More Than Ever, WHO Press."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"101860","DOI":"10.1016\/j.eclinm.2023.101860","article-title":"Global and regional prevalence of multimorbidity in the adult population in community settings: A systematic review and meta-analysis","volume":"57","author":"Chowdhury","year":"2023","journal-title":"eClinicalMedicine"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"102165","DOI":"10.1016\/j.arr.2023.102165","article-title":"Prevalence and patterns of multimorbidity in China during 2002\u20132022: A systematic review and meta-analysis","volume":"93","author":"Hu","year":"2024","journal-title":"Ageing Res. Rev."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1071\/PY12035","article-title":"Multimorbidity is associated with higher out-of-pocket spending: A study of older Australians with multiple chronic conditions","volume":"19","author":"McRae","year":"2013","journal-title":"Aust. J. Prim. Health"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1002\/alz.12094","article-title":"Health-care use and cost for multimorbid persons with dementia in the National Health and Aging Trends Study","volume":"16","author":"Thompson","year":"2020","journal-title":"Alzheimer\u2019s Dement. J. Alzheimer\u2019s Assoc."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/s40520-024-02835-2","article-title":"The prevalence of disability in older adults with multimorbidity: A meta-analysis","volume":"36","author":"Zhang","year":"2024","journal-title":"Aging Clin. Exp. Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ejim.2015.02.016","article-title":"Chronic conditions, disability, and quality of life in older adults with multimorbidity in Spain","volume":"26","author":"Forjaz","year":"2015","journal-title":"Eur. J. Intern. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jad.2017.06.009","article-title":"Multimorbidity and depression: A systematic review and meta-analysis","volume":"221","author":"Read","year":"2017","journal-title":"J. Affect. Disord."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1001\/archinte.162.20.2269","article-title":"Prevalence, expenditures, and complications of multiple chronic conditions in the elderly","volume":"162","author":"Wolff","year":"2002","journal-title":"Arch. Intern. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1136\/jech.2009.088260","article-title":"Comorbid chronic diseases, discordant impact on mortality in older people: A 14-year longitudinal population study","volume":"64","author":"Caughey","year":"2010","journal-title":"J. Epidemiol. Community Health"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2235042x18804063","DOI":"10.1177\/2235042X18804063","article-title":"Multimorbidity and mortality: A 15-year longitudinal registry-based nationwide Danish population study","volume":"8","author":"Willadsen","year":"2018","journal-title":"J. Comorbidity"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.archger.2016.07.008","article-title":"Multimorbidity and mortality in older adults: A systematic review and meta-analysis","volume":"67","author":"Nunes","year":"2016","journal-title":"Arch. Gerontol. Geriatr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"100903","DOI":"10.1016\/j.arr.2019.04.005","article-title":"Multimorbidity and quality of life: Systematic literature review and meta-analysis","volume":"53","author":"Makovski","year":"2019","journal-title":"Ageing Res. Rev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1002\/cncr.28509","article-title":"Annual Report to the Nation on the status of cancer, 1975\u20132010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer","volume":"120","author":"Edwards","year":"2014","journal-title":"Cancer"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.clnu.2024.01.008","article-title":"ESPEN practical guideline: Nutritional support for polymorbid medical inpatients","volume":"43","author":"Wunderle","year":"2024","journal-title":"Clin. Nutr."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"26335565251357781","DOI":"10.1177\/26335565251357781","article-title":"Stratification tools for assessing older adults with multimorbidity in an integrated care context: A scoping review","volume":"15","author":"Christensen","year":"2025","journal-title":"J. Multimorb. Comorbidity"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Guh, D.P., Zhang, W., Bansback, N., Amarsi, Z., Birmingham, C.L., and Anis, A.H. (2009). The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis. BMC Public Health, 9.","DOI":"10.1186\/1471-2458-9-88"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Piqueras, P., Ballester, A., Dur\u00e1-Gil, J.V., Martinez-Hervas, S., Red\u00f3n, J., and Real, J.T. (2021). Anthropometric Indicators as a Tool for Diagnosis of Obesity and Other Health Risk Factors: A Literature Review. Front. Psychol., 12.","DOI":"10.3389\/fpsyg.2021.631179"},{"key":"ref_19","unstructured":"NCD Risk Factor Collaboration (NCD-RisC) (2017). Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128\u00b79 million children, adolescents, and adults. Lancet, 390, 2627\u20132642."},{"key":"ref_20","unstructured":"World Obesity Federation (2024). World Obesity Atlas 2024, World Obesity Federation."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S2213-8587(21)00118-2","article-title":"Health policy and public health implications of obesity in China","volume":"9","author":"Wang","year":"2021","journal-title":"Lancet Diabetes Endocrinol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/ajpa.20262","article-title":"Relationship between adiposity and body size reveals limitations of BMI","volume":"129","author":"Nevill","year":"2006","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1038\/s41591-024-03095-3","article-title":"A new framework for the diagnosis, staging and management of obesity in adults","volume":"30","author":"Busetto","year":"2024","journal-title":"Nat. Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2890","DOI":"10.1111\/dom.15610","article-title":"Adiposity indicators exhibit depot- and sex-specific associations with multimorbidity onset: A cohort study of the UK Biobank","volume":"26","author":"Ma","year":"2024","journal-title":"Diabetes Obes. Metab."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"3238","DOI":"10.1111\/dom.15651","article-title":"Association between two novel anthropometric measures and type 2 diabetes in a Chinese population","volume":"26","author":"Wang","year":"2024","journal-title":"Diabetes Obes. Metab."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s13105-016-0525-1","article-title":"Usefulness of the conicity index together with the conjoint use of adipocytokines and nutritional-inflammatory markers in hemodialysis patients","volume":"73","author":"Ruperto","year":"2017","journal-title":"J. Physiol. Biochem."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1002\/clc.22437","article-title":"Conicity Index and Waist-to-Hip Ratio Are Superior Obesity Indices in Predicting 10-Year Cardiovascular Risk Among Men and Women","volume":"38","author":"Motamed","year":"2015","journal-title":"Clin. Cardiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1002\/oby.20408","article-title":"Relationships between body roundness with body fat and visceral adipose tissue emerging from a new geometrical model","volume":"21","author":"Thomas","year":"2013","journal-title":"Obesity"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"e034768","DOI":"10.1161\/JAHA.124.034768","article-title":"Body Roundness Index Trajectories and the Incidence of Cardiovascular Disease: Evidence From the China Health and Retirement Longitudinal Study","volume":"13","author":"Yang","year":"2024","journal-title":"J. Am. Heart Assoc."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"e2415051","DOI":"10.1001\/jamanetworkopen.2024.15051","article-title":"Body Roundness Index and All-Cause Mortality Among US Adults","volume":"7","author":"Zhang","year":"2024","journal-title":"JAMA Netw. Open"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Calder\u00f3n-Garc\u00eda, J.F., Roncero-Mart\u00edn, R., Rico-Mart\u00edn, S., De Nicol\u00e1s-Jim\u00e9nez, J.M., L\u00f3pez-Espuela, F., Santano-Mogena, E., Alfageme-Garc\u00eda, P., and S\u00e1nchez Mu\u00f1oz-Torrero, J.F. (2021). Effectiveness of Body Roundness Index (BRI) and a Body Shape Index (ABSI) in Predicting Hypertension: A Systematic Review and Meta-Analysis of Observational Studies. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph182111607"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1123\/jpah.6.6.790","article-title":"Global physical activity questionnaire (GPAQ): Nine country reliability and validity study","volume":"6","author":"Bull","year":"2009","journal-title":"J. Phys. Act. Health"},{"key":"ref_33","unstructured":"WHO (2010). Global Recommendations on Physical Activity for Health WHO, Geneva 2010, WHO."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1177\/08901171221104458","article-title":"Physical Activity and Multimorbidity Among Community-Dwelling Older Adults: A Systematic Review With Meta-Analysis","volume":"36","author":"Delpino","year":"2022","journal-title":"Am. J. Health Promot. AJHP"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"e1232","DOI":"10.1016\/S2214-109X(24)00150-5","article-title":"National, regional, and global trends in insufficient physical activity among adults from 2000 to 2022: A pooled analysis of 507 population-based surveys with 5\u00b77 million participants","volume":"12","author":"Strain","year":"2024","journal-title":"Lancet Glob. Health"},{"key":"ref_36","first-page":"e984","article-title":"Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association","volume":"143","author":"Poirier","year":"2021","journal-title":"Circulation"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/s41416-019-0500-z","article-title":"Obesity, abdominal obesity and subsequent risk of kidney cancer: A cohort study of 23.3 million East Asians","volume":"121","author":"Nam","year":"2019","journal-title":"Br. J. Cancer"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s12933-020-01095-4","article-title":"Associations between abdominal obesity indices and diabetic complications: Chinese visceral adiposity index and neck circumference","volume":"19","author":"Wan","year":"2020","journal-title":"Cardiovasc. Diabetol."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Larsson, S.C., and Burgess, S. (2021). Causal role of high body mass index in multiple chronic diseases: A systematic review and meta-analysis of Mendelian randomization studies. BMC Med., 19.","DOI":"10.1186\/s12916-021-02188-x"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1038\/nature05487","article-title":"Mechanisms linking obesity with cardiovascular disease","volume":"444","author":"Mertens","year":"2006","journal-title":"Nature"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"e277","DOI":"10.1016\/S2468-2667(17)30074-9","article-title":"Overweight, obesity, and risk of cardiometabolic multimorbidity: Pooled analysis of individual-level data for 120813 adults from 16 cohort studies from the USA and Europe","volume":"2","author":"Kuosma","year":"2017","journal-title":"Lancet Public Health"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"100130","DOI":"10.1016\/j.ajpc.2020.100130","article-title":"Inflammation and cardiovascular disease: From mechanisms to therapeutics","volume":"4","author":"Alfaddagh","year":"2020","journal-title":"Am. J. Prev. Cardiol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1464-5491.2004.01158.x","article-title":"The associations of body mass index, C-peptide and metabolic status in Chinese Type 2 diabetic patients","volume":"21","author":"Chan","year":"2004","journal-title":"Diabet. Med. A J. Br. Diabet. Assoc."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Zhou, D., Liu, X.C., Kenneth, L., Huang, Y.Q., and Feng, Y.Q. (2021). A Non-Linear Association of Triglyceride Glycemic Index With Cardiovascular and All-Cause Mortality Among Patients With Hypertension. Front. Cardiovasc. Med., 8.","DOI":"10.3389\/fcvm.2021.778038"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/978-3-031-63657-8_14","article-title":"Insulin Resistance, Obesity, and Lipotoxicity","volume":"1460","author":"Demir","year":"2024","journal-title":"Adv. Exp. Med. Biol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"e007292","DOI":"10.1161\/CIRCOUTCOMES.120.007292","article-title":"Obesity Prevalence and Risks Among Chinese Adults: Findings From the China PEACE Million Persons Project, 2014\u20132018","volume":"14","author":"Mu","year":"2021","journal-title":"Circ. Cardiovasc. Qual. Outcomes"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/s12933-019-0941-y","article-title":"Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes","volume":"18","author":"Son","year":"2019","journal-title":"Cardiovasc. Diabetol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4158\/EP161365.GL","article-title":"American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice Guidelines For Medical Care of Patients with Obesity","volume":"22","author":"Garvey","year":"2016","journal-title":"Endocr. Pract."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.clnu.2018.05.025","article-title":"Visceral adiposity index is associated with increased urinary albumin excretion: A population-based study","volume":"38","author":"Sun","year":"2019","journal-title":"Clin. Nutr."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/0002-9149(94)90676-9","article-title":"Waist circumference and abdominal sagittal diameter: Best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women","volume":"73","author":"Pouliot","year":"1994","journal-title":"Am. J. Cardiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1055\/s-2007-979126","article-title":"Conicity index as a predictor of blood pressure levels, insulin and triglyceride concentrations of healthy premenopausal women","volume":"28","author":"Mantzoros","year":"1996","journal-title":"Horm. Metab. Res."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"do Prado, C.B., Martins, C.A., Cremonini, A.C.P., Ferreira, J.R.S., Cattafesta, M., Almeida-de-Souza, J., Zandonade, E., Bezerra, O., and Salaroli, L.B. (2022). Cut Points of the Conicity Index and Associated Factors in Brazilian Rural Workers. Nutrients, 14.","DOI":"10.20944\/preprints202210.0128.v1"},{"key":"ref_53","first-page":"77","article-title":"A new index of abdominal adiposity as an indicator of risk for cardiovascular disease. A cross-population study","volume":"17","author":"Valdez","year":"1993","journal-title":"Int. J. Obes. Relat. Metab. Disord. J. Int. Assoc. Study Obes."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1017\/S0007114522002963","article-title":"Prevalence of adiposity-based chronic disease and its association with anthropometric and clinical indices: A cross-sectional study","volume":"130","year":"2023","journal-title":"Br. J. Nutr."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1590\/2359-3997000000187","article-title":"Association of the conicity index with diabetes and hypertension in Brazilian women","volume":"60","author":"Andrade","year":"2016","journal-title":"Arch. Endocrinol. Metab."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"100445","DOI":"10.1016\/j.jnha.2024.100445","article-title":"Association between cardiometabolic multimorbidity, body roundness index, and frailty index in Chinese middle-aged and older adults","volume":"29","author":"Zhang","year":"2025","journal-title":"J. Nutr. Health Aging"},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Geng, S., Chen, X., Shi, Z., Bai, K., and Shi, S. (2022). Association of anthropometric indices with the development of multimorbidity in middle-aged and older adults: A retrospective cohort study. PLoS ONE, 17.","DOI":"10.1371\/journal.pone.0276216"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"e190","DOI":"10.1017\/cts.2023.618","article-title":"Optimizing adaptive stepped-care interventions to change adults\u2019 health behaviors: A systematic review","volume":"7","author":"Roddy","year":"2023","journal-title":"J. Clin. Transl. Sci."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/18\/14\/2286\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T09:02:44Z","timestamp":1783933364000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/18\/14\/2286"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,13]]},"references-count":58,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2026,7]]}},"alternative-id":["nu18142286"],"URL":"https:\/\/doi.org\/10.3390\/nu18142286","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,13]]}}}