{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T05:04:52Z","timestamp":1784178292310,"version":"3.55.0"},"reference-count":73,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: Colorectal cancer (CRC) disproportionately affects Romania, where mortality exceeds the EU average and screening uptake remains low. Diet is among the most modifiable CRC risk factors, yet no validated instrument for assessing nutritional knowledge, attitudes, and practices (KAP) related to CRC prevention exists for the Romanian population. We developed and pilot-tested the EduNutriCRC questionnaire and characterised the corresponding nutritional KAP profile of Romanian adults. Methods: In a cross-sectional pilot study (April\u2013May 2026), a convenience sample of 301 Romanian adults aged 18\u201374 years completed the 51-item self-administered questionnaire. The instrument was evaluated for internal consistency and dimensional structure (exploratory factor analysis), with non-parametric tests used for group comparisons. Results: The composite knowledge score (C1\u2013C9; maximum 9) was 6.12 \u00b1 2.25 with wide item-level variation. Internal consistency was acceptable, and the Attitudes subscale resolved into two factors (Motivation &amp; Self-Efficacy and Perceived Barriers). Screening engagement was critically low (92.4% never tested; 81.7% unaware of the national programme). Although 64.1% expressed willingness to change their diet, 46.2% reported consuming processed meat at least weekly. Motivation &amp; Self-Efficacy, but not the knowledge score, was inversely correlated with risk-food consumption (\u03c1 = \u22120.39, p &lt; 0.001). Conclusions: EduNutriCRC demonstrated acceptable psychometric properties at the pilot stage. The study identified prevalent nutritional misconceptions, a marked knowledge\u2013behaviour gap, low screening awareness, and a structural mismatch between information sources used and those trusted. Attitudes and self-efficacy, rather than factual knowledge, were the more proximal correlates of dietary behaviour, supporting the development of self-efficacy-focused, culturally adapted educational interventions for CRC prevention in Romania, with EduNutriCRC serving as a baseline and monitoring instrument.<\/jats:p>","DOI":"10.3390\/nu18142293","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:55:21Z","timestamp":1783990521000},"page":"2293","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The EduNutriCRC Questionnaire: A Pilot Knowledge\u2013Attitudes\u2013Practices Study on Nutritional Prevention of Colorectal Cancer in Romanian Adults"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5219-5466","authenticated-orcid":false,"given":"Andreea-Adriana","family":"Neam\u021bu","sequence":"first","affiliation":[{"name":"Department of Toxicology, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"},{"name":"Research Centre for Pharmaco-Toxicological Evaluation, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"},{"name":"Department of Pathology, Clinical County Emergency Hospital of Arad, Andrenyi Karoly Str., No. 2\u20134, 310037 Arad, Romania"},{"name":"Department of Pathology, \u201cPius Brinzeu\u201d Clinical County Emergency Hospital Timi\u0219oara, Liviu Rebreanu Boulevard, No. 156, 300723 Timi\u0219oara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3818-5261","authenticated-orcid":false,"given":"Alina","family":"Anton","sequence":"additional","affiliation":[{"name":"Department of Toxicology, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"},{"name":"Research Centre for Pharmaco-Toxicological Evaluation, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8901-8271","authenticated-orcid":false,"given":"Laura","family":"Maghiar","sequence":"additional","affiliation":[{"name":"Department of Psycho-Neurosciences and Rehabilitation, Faculty of Medicine and Pharmacy, University of Oradea, Universit\u0103\u021bii Str., No. 1, 410087 Oradea, Romania"},{"name":"Department of Dermatovenerology, Clinical County Emergency Hospital Bihor, 410169 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrada","family":"Iftode","sequence":"additional","affiliation":[{"name":"Department of Toxicology, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"},{"name":"Research Centre for Pharmaco-Toxicological Evaluation, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5908-0231","authenticated-orcid":false,"given":"Anca-Maria","family":"C\u0103praru","sequence":"additional","affiliation":[{"name":"Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania"},{"name":"Department of Pharmacy, Poiana Mare Psychiatry Hospital, G\u0103rii Str., No. 40, 207470 Poiana Mare, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Dumitrescu","sequence":"additional","affiliation":[{"name":"Department of Toxicology, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"},{"name":"Research Centre for Pharmaco-Toxicological Evaluation, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4581-8487","authenticated-orcid":false,"given":"Andreea-Mihaela","family":"Kis","sequence":"additional","affiliation":[{"name":"Department of Management and Communication in Dental Medicine, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3852-9060","authenticated-orcid":false,"given":"Ramona Amina","family":"Popovici","sequence":"additional","affiliation":[{"name":"Department of Management and Communication in Dental Medicine, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina-Adriana","family":"Dehelean","sequence":"additional","affiliation":[{"name":"Department of Toxicology, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"},{"name":"Research Centre for Pharmaco-Toxicological Evaluation, \u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timi\u0219oara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teodor-Andrei","family":"Maghiar","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Pharmacy, University of Oradea, Universit\u0103\u021bii Str., No. 1, 410087 Oradea, Romania"},{"name":"Department of Surgery, Pelican Hospital, Corneliu Coposu Str., No. 2, 410450 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"ref_1","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J. Clin."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Wu, S., Zhang, Y., Lin, Z., and Wei, M. (2025). Global burden of colorectal cancer in 2022 and projections to 2050: Incidence and mortality estimates from GLOBOCAN. BMC Cancer, 25.","DOI":"10.1186\/s12885-025-15138-0"},{"key":"ref_3","unstructured":"OECD\/European Observatory on Health Systems and Policies (2025). EU Country Cancer Profile: Romania 2025, OECD Publishing."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"OECD (2024). Tackling the Impact of Cancer on Health, the Economy and Society, OECD Publishing. OECD Health Policy Studies.","DOI":"10.1787\/85e7c3ba-en"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S2468-1253(21)00426-X","article-title":"The rising tide of early-onset colorectal cancer: A comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection","volume":"7","author":"Patel","year":"2022","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41572-023-00432-7","article-title":"Young-onset colorectal cancer","volume":"9","author":"Spaander","year":"2023","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1056\/NEJMra2200869","article-title":"Increasing incidence of early-onset colorectal cancer","volume":"386","author":"Sinicrope","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1001\/jamaoncol.2025.4777","article-title":"Ultraprocessed Food Consumption and Risk of Early-Onset Colorectal Cancer Precursors Among Women","volume":"12","author":"Wang","year":"2026","journal-title":"JAMA Oncol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"164","DOI":"10.3390\/gidisord6010012","article-title":"The influence of ultra-processed food on colorectal cancer: A systematic review","volume":"6","year":"2024","journal-title":"Gastrointest. Disord."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"487","DOI":"10.21614\/chirurgia.2023.v.118.i.5.p.487","article-title":"Covid-19 and its impact on colorectal cancer diagnosis in Romania: A single-centred 5-year retrospective cohort study","volume":"118","author":"Maghiar","year":"2023","journal-title":"Chirurgia"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"37","DOI":"10.15403\/jgld-5380","article-title":"Introducing colorectal cancer screening in Romania\u2014Preliminary results from the regional pilot programs (ROCCAS)","volume":"33","author":"Manuc","year":"2024","journal-title":"J. Gastrointest. Liver Dis."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.21037\/jgo-22-510","article-title":"Barriers to colorectal cancer screening in the Eastern Mediterranean Region: A scoping review using the theoretical domains framework","volume":"14","author":"Hartley","year":"2023","journal-title":"J. Gastrointest. Oncol."},{"key":"ref_13","unstructured":"Romanian Ministry of Health (2022). National Cancer Prevention and Control Plan 2023\u20132030."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Belean, M.-C., Maghiar, T.-A., C\u0103praru, A.-M., Neam\u021bu, A.-A., Iliescu, D., Iovin, V.-C., Faur, F.-I., Bugi, M.-A., Totorean, A., and T\u0103ban, S. (2025). Acceptability of a colorectal cancer-preventive diet promoting red meat reduction and increased fiber and micronutrient intake: A cross-sectional study in Romanian adults. Nutrients, 17.","DOI":"10.3390\/nu17142386"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"5123","DOI":"10.1007\/s11357-025-01646-1","article-title":"Association between red and processed meat consumption and colorectal cancer risk: A comprehensive meta-analysis of prospective studies","volume":"47","author":"Ungvari","year":"2025","journal-title":"GeroScience"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1158\/0008-5472.CAN-14-2554","article-title":"A central role for heme iron in colon carcinogenesis associated with red meat intake","volume":"75","author":"Bastide","year":"2015","journal-title":"Cancer Res."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1007\/s00204-021-03064-6","article-title":"Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo","volume":"95","author":"Seiwert","year":"2021","journal-title":"Arch. Toxicol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"d6617","DOI":"10.1136\/bmj.d6617","article-title":"Dietary fibre, whole grains, and risk of colorectal cancer: Systematic review and dose-response meta-analysis of prospective studies","volume":"343","author":"Aune","year":"2011","journal-title":"BMJ"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1007\/s11357-024-01296-9","article-title":"Adherence to the Mediterranean diet and its protective effects against colorectal cancer: A meta-analysis of 26 studies with 2,217,404 participants","volume":"47","author":"Ungvari","year":"2025","journal-title":"GeroScience"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"113131","DOI":"10.1016\/j.nut.2026.113131","article-title":"Efficacy of Mediterranean diet for the primary prevention of oncological diseases: A systematic review and meta-analysis featured in the Italian National Guidelines \u201cLa Dieta Mediterranea\u201d","volume":"148","author":"Brunello","year":"2026","journal-title":"Nutrition"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s12672-024-01313-5","article-title":"Short-chain fatty acids play a positive role in colorectal cancer","volume":"15","author":"Liu","year":"2024","journal-title":"Discov. Oncol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1038\/s41591-022-01779-2","article-title":"Targeting the gut and tumor microbiota in cancer","volume":"28","author":"Park","year":"2022","journal-title":"Nat. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1038\/s41575-019-0209-8","article-title":"Gut microbiota in colorectal cancer: Mechanisms of action and clinical applications","volume":"16","author":"Wong","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1177\/10815589241277829","article-title":"The role of Fusobacterium nucleatum in the pathogenesis of colon cancer","volume":"72","author":"Hong","year":"2024","journal-title":"J. Investig. Med."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Paduraru, D.N., Palcau, A.C., Dinca, V.G., Ciuc, D.M., and Constantinescu, A. (2025). The role of gut microbiota in colorectal cancer pathogenesis: A comprehensive literature review. Int. J. Mol. Sci., 26.","DOI":"10.3390\/ijms262411870"},{"key":"ref_26","unstructured":"World Cancer Research Fund\/American Institute for Cancer Research (2018). Diet, Nutrition, Physical Activity and Cancer: A Global Perspective. Continuous Update Project Expert Report 2018."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/1878-0261.70201","article-title":"European Code Against Cancer, 5th edition\u2014Diet, excess body weight, physical activity, sedentary behavior, breastfeeding, and cancer","volume":"20","author":"Leitzmann","year":"2026","journal-title":"Mol. Oncol."},{"key":"ref_28","unstructured":"European Commission (2021). Europe\u2019s Beating Cancer Plan, European Commission. Communication from the Commission to the European Parliament and the Council; COM(2021) 44 final."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Sessa, A., Abbate, R., Di Giuseppe, G., Marinelli, P., and Angelillo, I.F. (2008). Knowledge, attitudes, and preventive practices about colorectal cancer among adults in an area of Southern Italy. BMC Cancer, 8.","DOI":"10.1186\/1471-2407-8-171"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Alkhaldy, A.A. (2025). Knowledge, attitudes, and practices toward colorectal cancer lifestyle risk factors among adults in Saudi Arabia. Front. Nutr., 12.","DOI":"10.3389\/fnut.2025.1507563"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"4503448","DOI":"10.1155\/2024\/4503448","article-title":"Knowledge, Awareness, and Practices toward Colorectal Cancer and Its Dietary and Lifestyle-Related Risk Factors among Jordanian University Students: A Cross-Sectional Study","volume":"2024","author":"Khraiwesh","year":"2024","journal-title":"J. Cancer Epidemiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1038\/s41430-020-0616-5","article-title":"Reliability and validity of a General Nutrition Knowledge Questionnaire for adults in a Romanian population","volume":"74","author":"Putnoky","year":"2020","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Forray, A.I., Coman, M.A., Chereche\u0219, R.M., and Borzan, C.M. (2023). Exploring the Impact of Sociodemographic Characteristics and Health Literacy on Adherence to Dietary Recommendations and Food Literacy. Nutrients, 15.","DOI":"10.3390\/nu15132853"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Boateng, G.O., Neilands, T.B., Frongillo, E.A., Melgar-Qui\u00f1onez, H.R., and Young, S.L. (2018). Best practices for developing and validating scales for health, social, and behavioral research: A primer. Front. Public Health, 6.","DOI":"10.3389\/fpubh.2018.00149"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1177\/109019817400200403","article-title":"Historical origins of the Health Belief Model","volume":"2","author":"Rosenstock","year":"1974","journal-title":"Health Educ. Monogr."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0749-5978(91)90020-T","article-title":"The theory of planned behavior","volume":"50","author":"Ajzen","year":"1991","journal-title":"Organ. Behav. Hum. Decis. Process."},{"key":"ref_37","unstructured":"Bandura, A. (1986). Social Foundations of Thought and Action: A Social Cognitive Theory, Prentice-Hall."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Tarta, C., Marian, M., Capitanio, M., Faur, F.I., Duta, C., Diaconescu, R., Oprescu-Macovei, A.M., Totolici, B., and Dobrescu, A. (2022). The Challenges of Colorectal Cancer Surgery during the COVID-19 Pandemic in Romania: A Three-Year Retrospective Study. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph192114320"},{"key":"ref_39","first-page":"3","article-title":"Estimating ordinal reliability for Likert-type and ordinal item response data: A conceptual, empirical, and practical guide","volume":"17","author":"Gadermann","year":"2012","journal-title":"Pract. Assess. Res. Eval."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"290","DOI":"10.2307\/270723","article-title":"Asymptotic confidence intervals for indirect effects in structural equation models","volume":"13","author":"Sobel","year":"1982","journal-title":"Sociol. Methodol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1080\/19312458.2012.679848","article-title":"Advantages of Monte Carlo confidence intervals for indirect effects","volume":"6","author":"Preacher","year":"2012","journal-title":"Commun. Methods Meas."},{"key":"ref_42","unstructured":"Hern\u00e1n, M.A., and Robins, J.M. (2020). Causal Inference: What If, Chapman & Hall\/CRC."},{"key":"ref_43","unstructured":"Hayes, A.F. (2018). Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach, Guilford Press. [2nd ed.]."},{"key":"ref_44","unstructured":"DeVellis, R.F., and Thorpe, C.T. (2021). Scale Development: Theory and Applications, SAGE Publications, Inc.. [5th ed.]."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"3510","DOI":"10.1007\/s12144-019-00300-2","article-title":"Exploratory factor analysis: Current use, methodological developments and recommendations for good practice","volume":"40","author":"Goretzko","year":"2021","journal-title":"Curr. Psychol."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Watkins, M.W. (2021). A Step-by-Step Guide to Exploratory Factor Analysis with R and RStudio, Routledge.","DOI":"10.4324\/9781003120001"},{"key":"ref_47","unstructured":"Brown, T.A. (2015). Confirmatory Factor Analysis for Applied Research, The Guilford Press. [2nd ed.]."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/S1470-2045(21)00199-6","article-title":"Colorectal cancer incidence, mortality, and stage distribution in European countries in the colorectal cancer screening era: An international population-based study","volume":"22","author":"Cardoso","year":"2021","journal-title":"Lancet Oncol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S2468-1253(22)00084-X","article-title":"Proportion and stage distribution of screen-detected and non-screen-detected colorectal cancer in nine European countries: An international, population-based study","volume":"7","author":"Cardoso","year":"2022","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.cgh.2020.02.026","article-title":"Differences in incidence and mortality trends of colorectal cancer worldwide based on sex, age, and anatomic location","volume":"19","author":"Wong","year":"2021","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/s41575-019-0253-4","article-title":"Early-onset colorectal cancer: Initial clues and current views","volume":"17","author":"Hofseth","year":"2020","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/s41575-023-00841-9","article-title":"Changing epidemiology of colorectal cancer\u2014Birth cohort effects and emerging risk factors","volume":"21","author":"Murphy","year":"2024","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"EVIDra2100035","DOI":"10.1056\/EVIDra2100035","article-title":"Colorectal cancer screening\u2014Approach, evidence, and future directions","volume":"1","author":"Helsingen","year":"2022","journal-title":"NEJM Evid."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"US Preventive Services Task Force (2021). Screening for colorectal cancer: US Preventive Services Task Force recommendation statement. JAMA, 325, 1965\u20131977.","DOI":"10.1001\/jama.2021.6238"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/S1470-2045(15)00444-1","article-title":"Carcinogenicity of consumption of red and processed meat","volume":"16","author":"Bouvard","year":"2015","journal-title":"Lancet Oncol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1007\/s10654-021-00741-9","article-title":"Consumption of red meat and processed meat and cancer incidence: A systematic review and meta-analysis of prospective studies","volume":"36","author":"Farvid","year":"2021","journal-title":"Eur. J. Epidemiol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"e2037341","DOI":"10.1001\/jamanetworkopen.2020.37341","article-title":"Role of diet in colorectal cancer incidence: Umbrella review of meta-analyses of prospective observational studies","volume":"4","author":"Veettil","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"ref_58","unstructured":"World Health Organization Regional Office for Europe (2022). WHO European Regional Obesity Report 2022, WHO Regional Office for Europe."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1093\/ajcn\/nqaa161","article-title":"Whole grain and dietary fiber intake and risk of colorectal cancer in the NIH-AARP Diet and Health Study cohort","volume":"112","author":"Hullings","year":"2020","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/jnci\/djaa164","article-title":"Comprehensive assessment of diet quality and risk of precursors of early-onset colorectal cancer","volume":"113","author":"Zheng","year":"2021","journal-title":"J. Natl. Cancer Inst."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1016\/j.clnu.2021.02.033","article-title":"Consumption of ultra-processed foods and drinks and colorectal, breast, and prostate cancer","volume":"40","author":"Romaguera","year":"2021","journal-title":"Clin. Nutr."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/S1470-2045(21)00279-5","article-title":"Global burden of cancer in 2020 attributable to alcohol consumption: A population-based study","volume":"22","author":"Rumgay","year":"2021","journal-title":"Lancet Oncol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"e17187","DOI":"10.2196\/17187","article-title":"Prevalence of health misinformation on social media: Systematic review","volume":"23","year":"2021","journal-title":"J. Med. Internet Res."},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"West, R., and Michie, S. (2020). A brief introduction to the COM-B Model of behaviour and the PRIME Theory of motivation. Qeios.","DOI":"10.32388\/WW04E6.2"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"n2061","DOI":"10.1136\/bmj.n2061","article-title":"A new framework for developing and evaluating complex interventions: Update of Medical Research Council guidance","volume":"374","author":"Skivington","year":"2021","journal-title":"BMJ"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"n332","DOI":"10.1136\/bmj.n332","article-title":"Changing behaviour: An essential component of tackling health inequalities","volume":"372","author":"Marteau","year":"2021","journal-title":"BMJ"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s41347-020-00134-x","article-title":"Social media and mental health: Benefits, risks, and opportunities for research and practice","volume":"5","author":"Naslund","year":"2020","journal-title":"J. Technol. Behav. Sci."},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Pelikan, J.M., Link, T., Stra\u00dfmayr, C., Waldherr, K., Alfers, T., B\u00f8ggild, H., Griebler, R., Lopatina, M., Mik\u0161ov\u00e1, D., and Nielsen, M.G. (2022). Measuring comprehensive, general health literacy in the general adult population: The development and validation of the HLS19-Q12 instrument in seventeen countries. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph192114129"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"m693","DOI":"10.1136\/bmj.m693","article-title":"Health equity in England: The Marmot review 10 years on","volume":"368","author":"Marmot","year":"2020","journal-title":"BMJ"},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Sarda, B., Julia, C., Serry, A.-J., and Ducrot, P. (2020). Appropriation of the front-of-pack nutrition label Nutri-Score across the French population: Evolution of awareness, support, and purchasing behaviors between 2018 and 2019. Nutrients, 12.","DOI":"10.3390\/nu12092887"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"76","DOI":"10.21101\/cejph.a6239","article-title":"International evidence for the effectiveness of the front-of-package nutrition label called Nutri-Score","volume":"29","author":"Andreeva","year":"2021","journal-title":"Cent. Eur. J. Public Health"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"e525","DOI":"10.1016\/S2214-109X(23)00042-6","article-title":"Non-communicable disease policy implementation from 2014 to 2021: A repeated cross-sectional analysis of global policy data for 194 countries","volume":"11","author":"Allen","year":"2023","journal-title":"Lancet Glob. Health"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"125","DOI":"10.12688\/wellcomeopenres.15906.2","article-title":"Delivering Behaviour Change Interventions: Development of a Mode of Delivery Ontology","volume":"5","author":"Marques","year":"2021","journal-title":"Wellcome Open Res."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/18\/14\/2293\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T04:24:18Z","timestamp":1784175858000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/18\/14\/2293"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,13]]},"references-count":73,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2026,7]]}},"alternative-id":["nu18142293"],"URL":"https:\/\/doi.org\/10.3390\/nu18142293","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,13]]}}}