{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:59:09Z","timestamp":1785430749330,"version":"3.56.0"},"reference-count":34,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009687","name":"Wroclaw Medical University","doi-asserted-by":"publisher","award":["SUBZ.L010.26.045"],"award-info":[{"award-number":["SUBZ.L010.26.045"]}],"id":[{"id":"10.13039\/501100009687","id-type":"DOI","asserted-by":"publisher"}]},{"award":["SUBZ.L010.26.045"],"award-info":[{"award-number":["SUBZ.L010.26.045"]}],"id":[{"id":"https:\/\/ror.org\/01qpw1b93","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Wroc\u0142aw University of Science and Technology"},{"id":[{"id":"https:\/\/ror.org\/008fyn775","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: Surgical treatment of colorectal cancer (CRC) is associated with a substantial risk of postoperative complications and delayed recovery of functional capacity, particularly in older patients and those with multiple comorbidities. Preoperative prehabilitation has emerged as a strategy aimed at optimizing patients\u2019 physical, nutritional, and psychological status prior to surgery; however, its clinical effectiveness and feasibility of implementation remain subjects of ongoing debate. The aim of this narrative review was to provide a clinically oriented synthesis of current evidence regarding multimodal prehabilitation in patients undergoing CRC surgery, with particular emphasis on perioperative outcomes, functional recovery, nutritional optimization, and implementation-related considerations. Methods: A targeted narrative review of the peer-reviewed literature indexed in PubMed (2015\u20132025) was conducted to identify contemporary review-type publications, including narrative reviews, systematic reviews, scoping reviews, and meta-analyses, addressing prehabilitation in CRC surgery. The findings were synthesized narratively and interpreted with emphasis on clinical applicability and translational relevance. Results: Twenty contemporary review publications were included in the analysis. Across the included publications, the most frequently reported favorable effects were observed for multimodal prehabilitation, incorporating physical exercise, nutritional support, and a psychological component. These interventions were associated with improvements in functional capacity and, in some meta-analyses, with a reduction in postoperative complication rates and shorter length of hospital stay, particularly in high-risk patients. Prehabilitation was assessed as safe and well tolerated. Conclusions: The current body of evidence indicates that multimodal prehabilitation may constitute a beneficial adjunct, particularly in improving functional capacity, while its impact on hard postoperative outcomes remains closely dependent on intervention quality, appropriate patient selection, and seamless integration with established perioperative care pathways. Future meta-analyses should address underexplored components of prehabilitation, including preparation for stoma formation and targeted educational and psychological support related to sexual health.<\/jats:p>","DOI":"10.3390\/nu18152457","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:08:14Z","timestamp":1785161294000},"page":"2457","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prehabilitation in Colorectal Cancer Surgery: A Narrative Review of Current Evidence and Clinical Perspectives"],"prefix":"10.3390","volume":"18","author":[{"given":"Dorota","family":"Zierkiewicz","sequence":"first","affiliation":[{"name":"Division of Anesthetic and Surgical Nursing, Faculty of Nursing and Midwifery, Wroclaw Medical University, 51-618 Wroclaw, Poland"},{"name":"Department of Gastrointestinal Cancer, Lower Silesian Oncology, Hematology and Pulmonology Center, 53-413 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4292-161X","authenticated-orcid":false,"given":"Stanis\u0142aw","family":"Manulik","sequence":"additional","affiliation":[{"name":"Division of Healthcare Organization, Department of Nursing, Faculty of Nursing and Midwifery, Wroclaw Medical University, 51-618 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3812-2869","authenticated-orcid":false,"given":"Anna","family":"Chudiak","sequence":"additional","affiliation":[{"name":"Division of Anesthetic and Surgical Nursing, Faculty of Nursing and Midwifery, Wroclaw Medical University, 51-618 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota","family":"Kr\u00f3wczy\u0144ska","sequence":"additional","affiliation":[{"name":"Intensive Cardiac Care Unit, Department of Heart Failure and Transplantation, Cardinal Stefan Wyszynski Institute of Cardiology in Warsaw, 04-628 Warsaw, Poland"},{"name":"Department of Nursing and Obstetrics, Collegium Mazovia, 08-110 Siedlce, Poland"},{"name":"Department of Nursing, Faculty of Rehabilitation, J\u00f3zef Pi\u0142sudski University of Physical Education in Warsaw, 00-968 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Homola","sequence":"additional","affiliation":[{"name":"Gynaecology and Obstetrics Centre FemiMea, 55-040 Bielany Wroclawskie, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Pobrotyn","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurosciences, Faculty of Medicine, Wroc\u0142aw University of Science and Technology, 51-377 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janecka","family":"Wioletta","sequence":"additional","affiliation":[{"name":"Department of Nursing, Faculty of Health Sciences, The Mazovian University in P\u0142ock, 09-402 P\u0142ock, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5734-116X","authenticated-orcid":false,"given":"Mariola","family":"G\u0142owacka","sequence":"additional","affiliation":[{"name":"Department of Nursing, Faculty of Health Sciences, The Mazovian University in P\u0142ock, 09-402 P\u0142ock, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u0142gorzata","family":"Paprocka-Borowicz","sequence":"additional","affiliation":[{"name":"Department of Neurological Rehabilitation, Regional Specialist Hospital in Wroclaw, 51-128 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9232-4525","authenticated-orcid":false,"given":"Mariusz","family":"Chabowski","sequence":"additional","affiliation":[{"name":"Department of Surgery, 4th Military Teaching Hospital in Wroclaw, 50-981 Wroc\u0142aw, Poland"},{"name":"Department of Clinical Surgical Sciences, Faculty of Medicine, Wroclaw University of Science and Technology, 51-377 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,27]]},"reference":[{"key":"ref_1","first-page":"89","article-title":"Epidemiology of Colorectal Cancer: Incidence, Mortality, Survival, and Risk Factors","volume":"14","author":"Rawla","year":"2019","journal-title":"Prz. 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