{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:56:35Z","timestamp":1791161795615,"version":"4.1.0"},"reference-count":146,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2012,8,13]],"date-time":"2012-08-13T00:00:00Z","timestamp":1344816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Eating disorders, including anorexia and bulimia nervosa, are potentially life-threatening syndromes characterized by severe disturbances in eating behavior. An effective treatment strategy for these conditions remains to be established, as patients with eating disorders tend to suffer from multiple relapses. Because ghrelin was originally discovered in the stomach mucosa, it has been widely studied over the past decade in an effort to uncover its potential roles; these studies have shed light on the mechanism by which ghrelin regulates food intake. Thus, studying ghrelin in the context of eating disorders could improve our understanding of the pathogenesis of eating disorders, possibly resulting in a promising new pharmacological treatment strategy for these patients. In addition, early detection and treatment of eating disorders are critical for ensuring recovery of young patients. Oral symptoms, including mucosal, dental, and saliva abnormalities, are typically observed in the early stages of eating disorders. Although oral care is not directly related to the treatment of eating disorders, knowledge of the oral manifestations of eating disorder patients may aid in early detection, resulting in earlier treatment; thus, oral care might contribute to overall patient management and prognosis. Moreover, ghrelin has also been found in saliva, which may be responsible for oral hygiene and digestion-related functions. This review discusses the pharmacological potential of ghrelin in regulating food-intake and the role of saliva and oral care in young patients with eating disorders.<\/jats:p>","DOI":"10.3390\/nu4080967","type":"journal-article","created":{"date-parts":[[2012,8,13]],"date-time":"2012-08-13T11:07:25Z","timestamp":1344856045000},"page":"967-989","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The Role of Ghrelin, Salivary Secretions, and Dental Care in Eating Disorders"],"prefix":"10.3390","volume":"4","author":[{"given":"Takakazu","family":"Yagi","sequence":"first","affiliation":[{"name":"Department of Orthodontics, Medical and Dental Hospital, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Ueda","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Medical and Dental Hospital, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruka","family":"Amitani","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Asakawa","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouichi","family":"Miyawaki","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Inui","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2012,8,13]]},"reference":[{"key":"ref_1","unstructured":"(2000). Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR, American Psychiatric Association. [4th]."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1176\/ajp.148.7.917","article-title":"50-year trends in the incidence of anorexia nervosa in Rochester, Minn.: A population-based study","volume":"148","author":"Lucas","year":"1991","journal-title":"Am. J. Psychiatry"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/01.yco.0000228759.95237.78","article-title":"Incidence, prevalence and mortality of anorexia nervosa and other eating disorders","volume":"19","author":"Hoek","year":"2006","journal-title":"Curr. Opin. Psychiatry"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1002\/eat.20316","article-title":"Time trends in the incidence of eating disorders: A primary care study in the Netherlands","volume":"39","author":"Bartelds","year":"2006","journal-title":"Int. J. Eat. Disord."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/45230","article-title":"Ghrelin is a growth-hormone-releasing acylated peptide from stomach","volume":"402","author":"Kojima","year":"1999","journal-title":"Nature"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/35086018","article-title":"Ghrelin: An orexigenic and somatotrophic signal from the stomach","volume":"2","author":"Inui","year":"2001","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Wren, A.M., Seal, L.J., Cohen, M.A., Brynes, A.E., Frost, G.S., Murphy, K.G., Dhillo, W.S., Ghatei, M.A., and Bloom, S.R. (2001). Ghrelin enhances appetite and increases food intake in humans. J. Clin. Endocrinol. Metab., 86.","DOI":"10.1210\/jcem.86.12.8111"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1136\/gut.52.7.947","article-title":"Antagonism of ghrelin receptor reduces food intake and body weight gain in mice","volume":"52","author":"Asakawa","year":"2003","journal-title":"Gut"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1373\/clinchem.2004.040667","article-title":"Identification of ghrelin in human saliva: Production by the salivary glands and potential role in proliferation of oral keratinocytes","volume":"51","author":"Groschl","year":"2005","journal-title":"Clin. Chem."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.peptides.2004.11.008","article-title":"A comparison of leptin and ghrelin levels in plasma and saliva of young healthy subjects","volume":"26","author":"Aydin","year":"2005","journal-title":"Peptides"},{"key":"ref_11","unstructured":"(1987). Diagnostic and Statistical Manual of Mental Disorders: DSM-III-R, American Psychiatric Association. [3rd]."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/eat.10222","article-title":"Review of the prevalence and incidence of eating disorders","volume":"34","author":"Hoek","year":"2003","journal-title":"Int. J. Eat. Disord."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/s11920-012-0282-y","article-title":"Epidemiology of eating disorders: Incidence, prevalence and mortality rates","volume":"14","author":"Smink","year":"2012","journal-title":"Curr. Psychiatry Rep."},{"key":"ref_14","first-page":"275","article-title":"Anorexia nervosa in Singapore: An eight-year retrospective study","volume":"46","author":"Lee","year":"2005","journal-title":"Singap. Med. J."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.appet.2009.11.008","article-title":"Body image and eating disorders amongst Japanese adolescents. A review of the literature","volume":"54","author":"Chisuwa","year":"2010","journal-title":"Appetite"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/ajmg.b.32000","article-title":"No association of brain-derived neurotrophic factor Val66Met polymorphism with anorexia nervosa in Japanese","volume":"159B","author":"Ando","year":"2012","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0193-953X(05)70375-0","article-title":"Epidemiology of the eating disorders","volume":"19","author":"Hsu","year":"1996","journal-title":"Psychiatr. Clin. N. Am."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1176\/appi.ajp.159.8.1284","article-title":"The outcome of anorexia nervosa in the 20th century","volume":"159","author":"Steinhausen","year":"2002","journal-title":"Am. J. Psychiatry"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.yhbeh.2006.06.030","article-title":"Understanding eating disorders","volume":"50","author":"Sodersten","year":"2006","journal-title":"Horm. Behav."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1093\/cercor\/bhn100","article-title":"Sex differences and the impact of steroid hormones on the developing human brain","volume":"19","author":"Neufang","year":"2009","journal-title":"Cereb. Cortex"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"S177","DOI":"10.1007\/s00406-011-0246-y","article-title":"Aetiology of anorexia nervosa: From a \u201cpsychosomatic family model\u201d to a neuropsychiatric disorder?","volume":"261","author":"Seitz","year":"2011","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1176\/appi.ajp.161.12.2215","article-title":"Comorbidity of anxiety disorders with anorexia and bulimia nervosa","volume":"161","author":"Kaye","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0140-6736(03)12378-1","article-title":"Eating disorders","volume":"361","author":"Fairburn","year":"2003","journal-title":"Lancet"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1176\/appi.ajp.160.11.2046","article-title":"Cognitive behavior therapy in the posthospitalization treatment of anorexia nervosa","volume":"160","author":"Pike","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/0006-3223(91)90180-T","article-title":"Feeding patterns in bulimia nervosa","volume":"30","author":"Weltzin","year":"1991","journal-title":"Biol. Psychiatry"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1017\/S0033291700037557","article-title":"Bulimia nervosa in Rochester, Minnesota from 1980 to 1990","volume":"25","author":"Soundy","year":"1995","journal-title":"Psychol. Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1192\/bjp.169.6.705","article-title":"The demand for eating disorder care. An epidemiological study using the general practice research database","volume":"169","author":"Turnbull","year":"1996","journal-title":"Br. J. Psychiatry"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/eat.10193","article-title":"Predicting the outcome of eating disorders using structural equation modeling","volume":"34","author":"Fichter","year":"2003","journal-title":"Int. J. Eat. Disord."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1017\/S0033291700038083","article-title":"Early onset bulimia nervosa: Who is at risk? A retrospective case-control study","volume":"22","author":"Schmidt","year":"1992","journal-title":"Psychol. Med."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0300-5712(95)00002-X","article-title":"Anorexia and bulimia nervosa (the eating disorders): Conditions of interest to the dental practitioner","volume":"24","author":"Robb","year":"1996","journal-title":"J. Dent."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1002\/j.0022-0337.2005.69.3.tb03921.x","article-title":"Knowledge of oral and physical manifestations of anorexia and bulimia nervosa among dentists and dental hygienists","volume":"69","author":"DeBate","year":"2005","journal-title":"J. Dent. Educ."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/BF03325007","article-title":"Oral manifestations in a group of young patients with anorexia nervosa","volume":"8","author":"Montecchi","year":"2003","journal-title":"Eat. Weight Disord."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0011-8532(22)00539-0","article-title":"Eating disorders in women\u2019s oral health","volume":"45","author":"Elliott","year":"2001","journal-title":"Dent. Clin. N. Am."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/erv.795","article-title":"Brief report: Decreased bone mineral density as a long-term complication of teenage-onset anorexia nervosa","volume":"15","author":"Wentz","year":"2007","journal-title":"Eur. Eat. Disord. Rev."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1002\/erv.812","article-title":"A study of bone density change in patients with anorexia nervosa","volume":"15","author":"Mascarenhas","year":"2007","journal-title":"Eur. Eat. Disord. Rev."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"87","DOI":"10.17796\/jcpd.33.2.d0kwj02t525t8177","article-title":"Oral health and bone density in adolescents and young women with anorexia nervosa","volume":"33","author":"Shaughnessy","year":"2008","journal-title":"J. Clin. Pediatr. Dent."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1124\/pr.109.001958","article-title":"Ghrelin gene products and the regulation of food intake and gut motility","volume":"61","author":"Chen","year":"2009","journal-title":"Pharmacol. Rev."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/j.1601-0825.2007.01422.x","article-title":"Oral manifestations of eating disorders: A critical review","volume":"14","author":"Campisi","year":"2008","journal-title":"Oral Dis."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/35007534","article-title":"Central nervous system control of food intake","volume":"404","author":"Schwartz","year":"2000","journal-title":"Nature"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1210\/en.2002-220795","article-title":"Agouti-related peptide, neuropeptide Y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus","volume":"144","author":"Seoane","year":"2003","journal-title":"Endocrinology"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/nature07181","article-title":"UCP2 mediates ghrelin\u2019s action on NPY\/AgRP neurons by lowering free radicals","volume":"454","author":"Andrews","year":"2008","journal-title":"Nature"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/00001756-200001170-00023","article-title":"Effect of 2-mercaptoacetate and 2-deoxy-D-glucose administration on the expression of NPY, AGRP, POMC, MCH and hypocretin\/orexin in the rat hypothalamus","volume":"11","author":"Sergeyev","year":"2000","journal-title":"Neuroreport"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0006-8993(99)01177-4","article-title":"Corticotropin-releasing factor receptor type 1 mediates emotional stress-induced inhibition of food intake and behavioral changes in rats","volume":"823","author":"Hotta","year":"1999","journal-title":"Brain Res."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1053\/gast.2001.22158","article-title":"Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin","volume":"120","author":"Asakawa","year":"2001","journal-title":"Gastroenterology"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1124\/jpet.102.034827","article-title":"Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure","volume":"302","author":"Banks","year":"2002","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"3454","DOI":"10.1210\/en.2002-220255","article-title":"Chicken ghrelin: Purification, cDNA cloning, and biological activity","volume":"143","author":"Kaiya","year":"2002","journal-title":"Endocrinology"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"40441","DOI":"10.1074\/jbc.M105212200","article-title":"Bullfrog ghrelin is modified by n-octanoic acid at its third threonine residue","volume":"276","author":"Kaiya","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"4143","DOI":"10.1210\/en.2002-220644","article-title":"Goldfish ghrelin: Molecular characterization of the complementary deoxyribonucleic acid, partial gene structure and evidence for its stimulatory role in food intake","volume":"143","author":"Unniappan","year":"2002","journal-title":"Endocrinology"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1006\/bbrc.2000.4039","article-title":"Ghrelin and des-acyl ghrelin: Two major forms of rat ghrelin peptide in gastrointestinal tissue","volume":"279","author":"Hosoda","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S1043-2760(00)00362-3","article-title":"Ghrelin: Discovery of the natural endogenous ligand for the growth hormone secretagogue receptor","volume":"12","author":"Kojima","year":"2001","journal-title":"Trends Endocrinol. Metab."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.regpep.2004.08.038","article-title":"Identification of ghrelin and its receptor in neurons of the rat arcuate nucleus","volume":"126","author":"Mondal","year":"2005","journal-title":"Regul. Pept."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1210\/en.2005-0174","article-title":"Molecular forms of hypothalamic ghrelin and its regulation by fasting and 2-deoxy-D-glucose administration","volume":"146","author":"Sato","year":"2005","journal-title":"Endocrinology"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/35051587","article-title":"A role for ghrelin in the central regulation of feeding","volume":"409","author":"Nakazato","year":"2001","journal-title":"Nature"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"4163","DOI":"10.1210\/endo.142.10.8490","article-title":"Minireview: Ghrelin and the regulation of energy balance\u2014a hypothalamic perspective","volume":"142","author":"Horvath","year":"2001","journal-title":"Endocrinology"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"4255","DOI":"10.1210\/endo.141.11.7757","article-title":"Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans","volume":"141","author":"Date","year":"2000","journal-title":"Endocrinology"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1136\/gut.2004.038737","article-title":"Stomach regulates energy balance via acylated ghrelin and desacyl ghrelin","volume":"54","author":"Asakawa","year":"2005","journal-title":"Gut"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1053\/gast.2002.35954","article-title":"The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats","volume":"123","author":"Date","year":"2002","journal-title":"Gastroenterology"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1373\/clinchem.2006.078956","article-title":"Simultaneous quantification of ghrelin and desacyl-ghrelin by liquid chromatography-tandem mass spectrometry in plasma, serum, and cell supernatants","volume":"53","author":"Rauh","year":"2007","journal-title":"Clin. Chem."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"R7","DOI":"10.1530\/eje.0.143r007","article-title":"Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats","volume":"143","author":"Seoane","year":"2000","journal-title":"Eur. J. Endocrinol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.2337\/diabetes.50.11.2540","article-title":"Ghrelin causes hyperphagia and obesity in rats","volume":"50","author":"Wren","year":"2001","journal-title":"Diabetes"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.regpep.2004.02.010","article-title":"Exogenous and endogenous ghrelin in gastroprotection against stress-induced gastric damage","volume":"120","author":"Brzozowski","year":"2004","journal-title":"Regul. Pept."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.regpep.2007.09.007","article-title":"Effects of ghrelin on glucose-sensing and gastric distension sensitive neurons in rat dorsal vagal complex","volume":"146","author":"Wang","year":"2008","journal-title":"Regul. Pept."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1113\/jphysiol.2003.040600","article-title":"Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats","volume":"550","author":"Fujino","year":"2003","journal-title":"J. Physiol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1111\/j.1440-1746.2011.06638.x","article-title":"Ghrelin family of peptides and gut motility","volume":"26","author":"Asakawa","year":"2011","journal-title":"J. Gastroenterol. Hepatol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1210\/en.2004-0629","article-title":"Transgenic mice overexpressing des-acyl ghrelin show small phenotype","volume":"146","author":"Ariyasu","year":"2005","journal-title":"Endocrinology"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0014-2999(03)02083-1","article-title":"Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin","volume":"476","author":"Bedendi","year":"2003","journal-title":"Eur. J. Pharmacol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1091\/mbc.e06-05-0402","article-title":"Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells","volume":"18","author":"Filigheddu","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/j.peptides.2005.10.011","article-title":"Stimulatory effect of n-octanoylated ghrelin on locomotor activity in the goldfish, Carassius auratus","volume":"27","author":"Matsuda","year":"2006","journal-title":"Peptides"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1126\/science.1117255","article-title":"Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin\u2019s effects on food intake","volume":"310","author":"Zhang","year":"2005","journal-title":"Science"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1136\/pgmj.61.711.3","article-title":"Gastrointestinal disturbance in anorexia nervosa","volume":"61","author":"Crisp","year":"1985","journal-title":"Postgrad. Med. J."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/BF03327494","article-title":"Plasma des-acyl and acyl ghrelin in patients with eating disorders","volume":"10","author":"Uehara","year":"2005","journal-title":"Eat. Weight Disord."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.regpep.2006.11.005","article-title":"Total ghrelin plasma level in patients with the restrictive type of anorexia nervosa","volume":"140","year":"2007","journal-title":"Regul. Pept."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0022-3956(02)00067-5","article-title":"Habitual binge\/purge behavior influences circulating ghrelin levels in eating disorders","volume":"37","author":"Tanaka","year":"2003","journal-title":"J. Psychiatr. Res."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1159\/000087923","article-title":"Plasma ghrelin in anorexia, bulimia, and binge-eating disorder: Relations with eating patterns and circulating concentrations of cortisol and thyroid hormones","volume":"81","author":"Troisi","year":"2005","journal-title":"Neuroendocrinology"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1055\/s-0031-1279703","article-title":"Increase in energy intake leads to a decrease in obestatin in restricting-type of anorexia nervosa","volume":"119","author":"Uehara","year":"2011","journal-title":"Exp. Clin. Endocrinol. Diabetes"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"4418","DOI":"10.1210\/jc.2008-1138","article-title":"Plasma obestatin, ghrelin, and ghrelin\/obestatin ratio are increased in underweight patients with anorexia nervosa but not in symptomatic patients with bulimia nervosa","volume":"93","author":"Monteleone","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"165","DOI":"10.33549\/physiolres.931952","article-title":"Changes of plasma obestatin, ghrelin and NPY in anorexia and bulimia nervosa patients before and after a high-carbohydrate breakfast","volume":"60","author":"Sedlackova","year":"2011","journal-title":"Physiol. Res."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/S0306-4530(02)00066-5","article-title":"Fasting plasma ghrelin levels in subtypes of anorexia nervosa","volume":"28","author":"Tanaka","year":"2003","journal-title":"Psychoneuroendocrinology"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.regpep.2004.06.015","article-title":"Effect of nutritional rehabilitation on circulating ghrelin and growth hormone levels in patients with anorexia nervosa","volume":"122","author":"Tanaka","year":"2004","journal-title":"Regul. Pept."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1210\/jc.2002-021669","article-title":"Loss of meal-induced decrease in plasma ghrelin levels in patients with anorexia nervosa","volume":"88","author":"Nedvidkova","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1210\/jc.2003-031861","article-title":"Growth hormone and ghrelin responses to an oral glucose load in adolescent girls with anorexia nervosa and controls","volume":"89","author":"Misra","year":"2004","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1677\/joe.0.175r001","article-title":"Plasma ghrelin concentrations in elderly subjects: Comparison with anorexic and obese patients","volume":"175","author":"Rigamonti","year":"2002","journal-title":"J. Endocrinol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1210\/jc.2002-020645","article-title":"Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women","volume":"88","author":"Tolle","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"E347","DOI":"10.1152\/ajpendo.00615.2004","article-title":"Secretory dynamics of ghrelin in adolescent girls with anorexia nervosa and healthy adolescents","volume":"289","author":"Misra","year":"2005","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1530\/EJE-1450669","article-title":"Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa","volume":"145","author":"Otto","year":"2001","journal-title":"Eur. J. Endocrinol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1210\/jc.2005-2304","article-title":"Ghrelin has partial or no effect on appetite, growth hormone, prolactin, and cortisol release in patients with anorexia nervosa","volume":"91","author":"Miljic","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.psyneuen.2008.10.001","article-title":"Ghrelin\/obestatin ratio in two populations with low bodyweight: Constitutional thinness and anorexia nervosa","volume":"34","author":"Germain","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.biopsych.2007.04.005","article-title":"Obestatin, acyl ghrelin, and des-acyl ghrelin responses to an oral glucose tolerance test in the restricting type of anorexia nervosa","volume":"63","author":"Harada","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"5707","DOI":"10.1210\/jc.2004-0353","article-title":"Plasma levels of intact and degraded ghrelin and their responses to glucose infusion in anorexia nervosa","volume":"89","author":"Hotta","year":"2004","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1055\/s-0030-1252017","article-title":"Changes in acyl ghrelin, des-acyl ghrelin, and ratio of acyl ghrelin to total ghrelin with short-term refeeding in female inpatients with restricting-type anorexia nervosa","volume":"42","author":"Koyama","year":"2010","journal-title":"Horm. Metab. Res."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.peptides.2010.10.004","article-title":"Plasma nesfatin-1 concentrations in restricting-type anorexia nervosa","volume":"32","author":"Ogiso","year":"2011","journal-title":"Peptides"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.biopsych.2007.08.005","article-title":"Plasma obestatin concentrations are negatively correlated with body mass index, insulin resistance index, and plasma leptin concentrations in obesity and anorexia nervosa","volume":"64","author":"Nakahara","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1507\/endocrj.K09E-168","article-title":"Ghrelin increases hunger and food intake in patients with restricting-type anorexia nervosa: A pilot study","volume":"56","author":"Hotta","year":"2009","journal-title":"Endocr. J."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1530\/eje.0.146r001","article-title":"Increased fasting plasma ghrelin levels in patients with bulimia nervosa","volume":"146","author":"Tanaka","year":"2002","journal-title":"Eur. J. Endocrinol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.psyneuen.2009.07.001","article-title":"Enhanced ghrelin secretion in the cephalic phase of food ingestion in women with bulimia nervosa","volume":"35","author":"Monteleone","year":"2010","journal-title":"Psychoneuroendocrinology"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1365-2265.2004.02176.x","article-title":"Altered ghrelin and peptide YY responses to meals in bulimia nervosa","volume":"62","author":"Kojima","year":"2005","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1017\/S0033291704003368","article-title":"Circulating brain-derived neurotrophic factor is decreased in women with anorexia and bulimia nervosa but not in women with binge-eating disorder: Relationships to co-morbid depression, psychopathology and hormonal variables","volume":"35","author":"Monteleone","year":"2005","journal-title":"Psychol. Med."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.psyneuen.2004.12.008","article-title":"Hormonal and metabolic responses to acute ghrelin administration in patients with bulimia nervosa","volume":"30","author":"Fassino","year":"2005","journal-title":"Psychoneuroendocrinology"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"407","DOI":"10.14219\/jada.archive.1987.0262","article-title":"Oral findings in anorexia nervosa and bulimia nervosa: A study of 47 cases","volume":"115","author":"Roberts","year":"1987","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_100","first-page":"178","article-title":"Dental aspects of anorexia and bulimia nervosa","volume":"16","author":"Roberts","year":"1989","journal-title":"Pediatrician"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1067\/moe.2002.116598","article-title":"Eating disorders: Dental implications","volume":"93","author":"Little","year":"2002","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/j.1834-7819.2005.tb00079.x","article-title":"Eating disorders and oral health: A review of the literature","volume":"50","author":"Frydrych","year":"2005","journal-title":"Aust. Dent. J."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/sj.bdj.4808695","article-title":"The distribution of erosion in the dentitions of patients with eating disorders","volume":"178","author":"Robb","year":"1995","journal-title":"Br. Dent. J."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/0030-4220(80)90433-8","article-title":"The anorexia nervosa syndrome","volume":"50","author":"Brady","year":"1980","journal-title":"Oral Surg. Oral Med. Oral Pathol."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"723","DOI":"10.14219\/jada.archive.1984.0186","article-title":"Dental sequelae to the binge-purge syndrome (bulimia): Report of cases","volume":"109","author":"Wolcott","year":"1984","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_106","first-page":"71","article-title":"Oral complications in anorexia nervosa","volume":"85","author":"Hellstrom","year":"1977","journal-title":"Scand. J. Dent. Res."},{"key":"ref_107","first-page":"134","article-title":"Oral complications of anorexia nervosa and\/or bulimia: With a review of the literature","volume":"40","author":"Clark","year":"1985","journal-title":"J. Oral Med."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/sj.bdj.4806915","article-title":"The orodental status of anorexics and bulimics","volume":"167","author":"Milosevic","year":"1989","journal-title":"Br. Dent. J."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"586","DOI":"10.14219\/jada.archive.1947.0133","article-title":"Dissolution of tooth substance by lemon juice, acid beverages and acids from some other sources","volume":"34","author":"Stafne","year":"1947","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"618","DOI":"10.14219\/jada.archive.1984.0395","article-title":"Dental management of the chronic vomiting patient","volume":"108","author":"Kleier","year":"1984","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_111","first-page":"10","article-title":"Eating disorders: The untold story","volume":"89","author":"Hamilton","year":"1996","journal-title":"CDS Rev."},{"key":"ref_112","first-page":"837","article-title":"Oral scurvy and periodontal disease","volume":"63","author":"Touyz","year":"1997","journal-title":"J. Can. Dent. Assoc."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1002\/(SICI)1097-0347(199812)20:8<758::AID-HED16>3.0.CO;2-N","article-title":"Sialadenosis: A presenting sign in bulimia","volume":"20","author":"Coleman","year":"1998","journal-title":"Head Neck"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/154411130401500405","article-title":"Adverse drug reactions in the orofacial region","volume":"15","author":"Scully","year":"2004","journal-title":"Crit. Rev. Oral Biol. Med."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1177\/00220345910700060601","article-title":"Risk factors in dental erosion","volume":"70","author":"Jarvinen","year":"1991","journal-title":"J. Dent. Res."},{"key":"ref_116","first-page":"160","article-title":"A comparison of acidic dietary factors in children with and without dental erosion","volume":"67","author":"Curzon","year":"2000","journal-title":"ASDC J. Dent. Child."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"e39","DOI":"10.1016\/j.tripleo.2006.08.005","article-title":"Necrotizing sialometaplasia associated with bulimia: Case report and literature review","volume":"103","author":"Solomon","year":"2007","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1113\/expphysiol.1996.sp003934","article-title":"The effects of unilateral and bilateral chewing, empty clenching and simulated bruxism, on the masticatory-parotid salivary reflex in man","volume":"81","author":"Anderson","year":"1996","journal-title":"Exp. Physiol."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/0006-8993(94)91057-X","article-title":"Effect of salivation on neural taste responses in freely moving rats: Analyses of salivary secretion and taste responses of the chorda tympani nerve","volume":"649","author":"Matsuo","year":"1994","journal-title":"Brain Res."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0165-1838(89)90168-9","article-title":"Gustatory-salivary reflex: Neural activity of sympathetic and parasympathetic fibers innervating the submandibular gland of the hamster","volume":"26","author":"Matsuo","year":"1989","journal-title":"J. Auton. Nerv. Syst."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.ajodo.2004.02.007","article-title":"Relationships among nocturnal jaw muscle activities, decreased esophageal pH, and sleep positions","volume":"126","author":"Miyawaki","year":"2004","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"409","DOI":"10.14219\/jada.archive.1994.0059","article-title":"Salivary gland dysfunction: Causes, symptoms, treatment","volume":"125","author":"Atkinson","year":"1994","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s11010-009-0381-1","article-title":"Ghrelin and obestatin expression in oral squamous cell carcinoma: An immunohistochemical and biochemical study","volume":"339","author":"Alnema","year":"2010","journal-title":"Mol. Cell. Biochem."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1365-2842.2007.01794.x","article-title":"Salivary secretion, taste and hyposalivation","volume":"34","author":"Mese","year":"2007","journal-title":"J. Oral Rehabil."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF00305729","article-title":"Secretory responses in granular ducts and acini of submandibular glands in vivo to parasympathetic or sympathetic nerve stimulation in rats","volume":"264","author":"Garrett","year":"1991","journal-title":"Cell Tissue Res."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1159\/000201432","article-title":"Oesophageal acid and salivary secretion: Is chewing gum a treatment option for gastro-oesophageal reflux?","volume":"58","author":"Hector","year":"1997","journal-title":"Digestion"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1523\/JNEUROSCI.04-05-01208.1984","article-title":"Lateral hypothalamic modulation of the gustatory-salivary reflex in rats","volume":"4","author":"Matsuo","year":"1984","journal-title":"J. Neurosci."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1523\/JNEUROSCI.04-05-01201.1984","article-title":"Lateral hypothalamic modulation of oral sensory afferent activity in nucleus tractus solitarius neurons of rats","volume":"4","author":"Matsuo","year":"1984","journal-title":"J. Neurosci."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.autneu.2006.10.006","article-title":"Regulation of salivary gland function by autonomic nerves","volume":"133","author":"Proctor","year":"2007","journal-title":"Auton. Neurosci."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1177\/0022034511420431","article-title":"Expression and possible immune-regulatory function of ghrelin in oral epithelium","volume":"90","author":"Ohta","year":"2011","journal-title":"J. Dent. Res."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.archoralbio.2010.10.014","article-title":"Expression of ghrelin in human salivary glands and its levels in saliva and serum in Chinese obese children and adolescents","volume":"56","author":"Li","year":"2011","journal-title":"Arch. Oral Biol."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s10654-011-9585-2","article-title":"Reliability of hypothalamic-pituitary-adrenal axis assessment methods for use in population-based studies","volume":"26","author":"Golden","year":"2011","journal-title":"Eur. J. Epidemiol."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"679","DOI":"10.7150\/ijms.8.679","article-title":"Anorexia nervosa: A unified neurological perspective","volume":"8","author":"Hasan","year":"2011","journal-title":"Int. J. Med. Sci."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0165-1781(96)02985-X","article-title":"Neuropeptide abnormalities in anorexia nervosa","volume":"62","author":"Kaye","year":"1996","journal-title":"Psychiatry Res."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1017\/S0033291711000092","article-title":"Asymmetry of salivary cortisol and alpha-amylase responses to psychosocial stress in anorexia nervosa but not in bulimia nervosa","volume":"41","author":"Monteleone","year":"2011","journal-title":"Psychol. Med."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"455","DOI":"10.3109\/15622975.2011.590226","article-title":"Abnormal diurnal patterns of salivary alpha-amylase and cortisol secretion in acute patients with anorexia nervosa","volume":"12","author":"Monteleone","year":"2011","journal-title":"World J. Biol. Psychiatry"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1475-097X.1996.tb00731.x","article-title":"Salivary alpha-amylase as a measure of endogenous adrenergic activity","volume":"16","author":"Chatterton","year":"1996","journal-title":"Clin. Physiol."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jpsychires.2004.08.001","article-title":"A retrospective study of SSRI treatment in adolescent anorexia nervosa: Insufficient evidence for efficacy","volume":"39","author":"Holtkamp","year":"2005","journal-title":"J. Psychiatr. Res."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1177\/0009922807303929","article-title":"Pharmacological treatment of anorexia nervosa: A retrospective study in preadolescents and adolescents","volume":"46","author":"Rossi","year":"2007","journal-title":"Clin. Pediatr. (Phila.)"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/j.1365-2826.2010.02019.x","article-title":"The ghrelin\/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake","volume":"22","author":"Hassouna","year":"2010","journal-title":"J. Neuroendocrinol."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1001\/archpsyc.1987.01800240021004","article-title":"An evaluation of family therapy in anorexia nervosa and bulimia nervosa","volume":"44","author":"Russell","year":"1987","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1001\/archpsyc.1997.01830230063008","article-title":"Family and individual therapy in anorexia nervosa. A 5-year follow-up","volume":"54","author":"Eisler","year":"1997","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1001\/archpsyc.59.12.1105","article-title":"Relapse predictors of patients with bulimia nervosa who achieved abstinence through cognitive behavioral therapy","volume":"59","author":"Halmi","year":"2002","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_144","first-page":"60","article-title":"Eating disorders in adolescents","volume":"99","author":"Burns","year":"2003","journal-title":"W. Va. Med. J."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0011-8532(22)00545-6","article-title":"Women\u2019s health and oral health implications of the curriculum study","volume":"45","author":"Silverton","year":"2001","journal-title":"Dent. Clin. N. Am."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/j.0022-0337.1990.54.3.tb02404.x","article-title":"Bulimia and anorexia nervosa in dental and dental hygiene curricula","volume":"54","author":"Gross","year":"1990","journal-title":"J. Dent. Educ."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/4\/8\/967\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:51:46Z","timestamp":1760219506000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/4\/8\/967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,13]]},"references-count":146,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2012,8]]}},"alternative-id":["nu4080967"],"URL":"https:\/\/doi.org\/10.3390\/nu4080967","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,13]]}}}