{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T07:51:05Z","timestamp":1778399465097,"version":"3.51.4"},"reference-count":46,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T00:00:00Z","timestamp":1461801600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Guangzhou Science and Technology Bureau","award":["2011Y2-00025, 2012J5100038, and 201508030037"],"award-info":[{"award-number":["2011Y2-00025, 2012J5100038, and 201508030037"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>There was limited evidence revealing the association of Chinese maternal dietary patterns with fetal growth. We aimed to examine the relationship of maternal dietary patterns during pregnancy to neonatal birth weight and birth weight for gestational age in a Chinese population. A total of 6954 mother-child pairs were included from the Born in Guangzhou Cohort Study. Maternal diet during pregnancy was assessed using a self-administered food frequency questionnaire. Cluster analysis was used to identify dietary patterns. The following six dietary patterns were identified: \u201cCereals, eggs, and Cantonese soups\u201d (n 1026, 14.8%), \u201cDairy\u201d (n 1020, 14.7%), \u201cFruits, nuts, and Cantonese desserts\u201d (n 799, 11.5%), \u201cMeats\u201d (n 1066, 15.3%), \u201cVegetables\u201d (n 1383, 19.9%), and \u201cVaried\u201d (n 1224, 17.6%). The mean neonatal birth weight Z scores of women in the above patterns were 0.02, 0.07, 0.20, 0.01, 0.06, and 0.14, respectively. Women in the \u201cFruits, nuts, and Cantonese desserts\u201d and \u201cVaried\u201d groups had significantly heavier infants compared with those in the \u201cCereals, eggs, and Cantonese soups\u201d group. Compared with women in the \u201cCereals, eggs, and Cantonese soups\u201d group, those in the \u201cVaried\u201d group had marginally significantly lower odds of having a small-for-gestational age (SGA) infant after adjustment for other confounders (OR 0.77, 95% CI 0.57, 1.04, p = 0.08). These findings suggest that compared to a traditional Cantonese diet high in cereals, eggs, and Cantonese soups, a diet high in fruits, nuts, and Cantonese desserts might be associated with a higher birth weight, while a varied diet might be associated with a greater birth weight and also a decreased risk of having a SGA baby.<\/jats:p>","DOI":"10.3390\/nu8050257","type":"journal-article","created":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T10:25:55Z","timestamp":1461839155000},"page":"257","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Maternal Dietary Patterns and Fetal Growth: A Large Prospective Cohort Study in China"],"prefix":"10.3390","volume":"8","author":[{"given":"Min-Shan","family":"Lu","sequence":"first","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiao-Zhu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Rong","family":"He","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue-Ling","family":"Wei","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Hua","family":"Lu","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng-Hui","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing-Xuan","family":"Wen","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan-Fan","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nian-Nian","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Qiu","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Bi","family":"Mai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui-Fang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cui-Yue","family":"Hu","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Min","family":"Xia","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiu","family":"Qiu","sequence":"additional","affiliation":[{"name":"Division of Birth Cohort Study, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, 9 Junsui Road, Tianhe District, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2016,4,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1053\/j.ajkd.2008.12.042","article-title":"Is low birth weight an antecedent of ckd in later life? A systematic review of observational studies","volume":"54","author":"White","year":"2009","journal-title":"Am. J. Kidney Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1001\/jama.2008.886","article-title":"Birth weight and risk of type 2 diabetes: A systematic review","volume":"300","author":"Whincup","year":"2008","journal-title":"JAMA"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1017\/S2040174414000440","article-title":"Birth weight and risk of coronary heart disease in adults: A meta-analysis of prospective cohort studies","volume":"5","author":"Wang","year":"2014","journal-title":"J. Dev. Orig. Health Dis."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1097\/HCO.0000000000000180","article-title":"Birth weight and arterial hypertension","volume":"30","author":"Bruno","year":"2015","journal-title":"Curr. Opin. Cardiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1038\/ijo.2011.248","article-title":"High birth weight and obesity--a vicious circle across generations","volume":"36","author":"Cnattingius","year":"2012","journal-title":"Int. J. Obes. (Lond.)"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1002\/ijc.29900","article-title":"Sex-specific associations between birth weight and adult primary liver cancer in a large cohort of danish children","volume":"138","author":"Zimmermann","year":"2015","journal-title":"Int. J. Cancer"},{"key":"ref_7","first-page":"382","article-title":"Evaluating the role of birth weight and gestational age on acute lymphoblastic leukemia risk among those of hispanic ethnicity","volume":"32","author":"Barahmani","year":"2015","journal-title":"Pediatr. Hematol. Oncol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/ije\/dyu265","article-title":"Infant birthweight and risk of childhood cancer: International population-based case control studies of 40 000 cases","volume":"44","author":"Murphy","year":"2015","journal-title":"Int. J. Epidemiol."},{"key":"ref_9","first-page":"203","article-title":"Fetal development and risk of cardiovascular diseases and diabetes type 2 in adult life","volume":"15","author":"Szamotulska","year":"2011","journal-title":"Med. Wieku. Rozwoj."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1017\/S0029665115002396","article-title":"Improving maternal nutrition for better pregnancy outcomes","volume":"74","author":"Nnam","year":"2015","journal-title":"Proc. Nutr. Soc."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1080\/14034940600717688","article-title":"Association between fruit and vegetable consumption and birth weight: A prospective study among 43,585 danish women","volume":"34","author":"Mikkelsen","year":"2006","journal-title":"Scand. J. Public Health"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1093\/ajcn\/87.4.887","article-title":"Maternal n-3, n-6, and trans fatty acid profile early in pregnancy and term birth weight: A prospective cohort study","volume":"87","author":"Hornstra","year":"2008","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1093\/humrep\/der005","article-title":"Dietary iron intake during early pregnancy and birth outcomes in a cohort of british women","volume":"26","author":"Alwan","year":"2011","journal-title":"Hum. Reprod."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1365-3016.2012.01292.x","article-title":"Effect of n-3 long-chain polyunsaturated fatty acid intake during pregnancy on maternal, infant, and child health outcomes: A systematic review","volume":"26","author":"Briggs","year":"2012","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1289\/ehp.1206333","article-title":"Bulky dna adducts in cord blood, maternal fruit-and-vegetable consumption, and birth weight in a european mother-child study (newgeneris)","volume":"121","author":"Pedersen","year":"2013","journal-title":"Environ. Health Perspect."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1475-2891-12-20","article-title":"Micronutrients and pregnancy; effect of supplementation on pregnancy and pregnancy outcomes: A systematic review","volume":"12","author":"Zerfu","year":"2013","journal-title":"Nutr. J."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.3945\/jn.114.205948","article-title":"Maternal protein intake during pregnancy is not associated with offspring birth weight in a multiethnic asian population","volume":"145","author":"Chong","year":"2015","journal-title":"J. Nutr."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/00041433-200202000-00002","article-title":"Dietary pattern analysis: A new direction in nutritional epidemiology","volume":"13","author":"Hu","year":"2002","journal-title":"Curr. Opin. Lipidol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/026010609501000203","article-title":"Maternal eating patterns and birth weight of mexican american infants","volume":"10","author":"Wolff","year":"1995","journal-title":"Nutr. Health"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/sj.ejcn.1602745","article-title":"Major dietary patterns in pregnancy and fetal growth","volume":"62","author":"Knudsen","year":"2008","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1038\/sj.ejcn.1602789","article-title":"Adjusting for energy intake in dietary pattern investigations using principal components analysis","volume":"62","author":"Northstone","year":"2008","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1017\/S0007114509993606","article-title":"Maternal dietary patterns in pregnancy and the association with small-for-gestational-age infants","volume":"103","author":"Thompson","year":"2010","journal-title":"Br. J. Nutr."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1017\/S0007114511004636","article-title":"Maternal dietary patterns in pregnancy and fetal growth in japan: The osaka maternal and child health study","volume":"107","author":"Okubo","year":"2012","journal-title":"Br. J. Nutr."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/S0034-8910.2015049005403","article-title":"Dietary patterns in pregnancy and birth weight","volume":"49","author":"Cunha","year":"2015","journal-title":"Rev. Saude Publica"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.3390\/nu7021318","article-title":"Association between dietary patterns during pregnancy and birth size measures in a diverse population in southern us","volume":"7","author":"Racette","year":"2015","journal-title":"Nutrients"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.3945\/jn.114.190686","article-title":"Preconception dietary patterns in human pregnancies are associated with preterm delivery","volume":"144","author":"Grieger","year":"2014","journal-title":"J. Nutr."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"2933","DOI":"10.3390\/nu5082933","article-title":"Dietary intake and food habits of pregnant women residing in urban and rural areas of deyang city, sichuan province, china","volume":"5","author":"Gao","year":"2013","journal-title":"Nutrients"},{"key":"ref_28","first-page":"229","article-title":"A dietary survey of the chinese population in urban and rural areas of tianjin","volume":"5","author":"Tian","year":"1996","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1017\/S0007114515000707","article-title":"Maternal dietary patterns and gestational diabetes mellitus: A large prospective cohort study in china","volume":"113","author":"He","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1136\/archdischild-2013-305923","article-title":"A new birthweight reference in guangzhou, southern china, and its comparison with the global reference","volume":"99","author":"He","year":"2014","journal-title":"Arch. Dis. Child."},{"key":"ref_31","first-page":"1","article-title":"The guidelines for prevention and control of overweight and obesity in chinese adults","volume":"17","author":"Chen","year":"2004","journal-title":"Biomed. Environ. Sci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1017\/S1368980010002521","article-title":"Nutritional adequacy of three dietary patterns defined by cluster analysis in 997 pregnant japanese women: The osaka maternal and child health study","volume":"14","author":"Okubo","year":"2011","journal-title":"Public Health Nutr."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1136\/bmj.312.7028.410","article-title":"Maternal nutrition in early and late pregnancy in relation to placental and fetal growth","volume":"312","author":"Godfrey","year":"1996","journal-title":"BMJ"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1542\/peds.2005-2374","article-title":"Dietary recommendations for children and adolescents: A guide for practitioners","volume":"117","author":"Gidding","year":"2006","journal-title":"Pediatrics"},{"key":"ref_35","unstructured":"(2010). Dietary Guidelines for American."},{"key":"ref_36","unstructured":"Chinese Nutrition Society (2009). Dietary Guidelines for Chinese Residents, Tibet People\u2019s Press."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3390\/nu7010153","article-title":"A review of the impact of dietary intakes in human pregnancy on infant birthweight","volume":"7","author":"Grieger","year":"2015","journal-title":"Nutrients"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/jn\/131.4.1217","article-title":"Intake of micronutrient-rich foods in rural indian mothers is associated with the size of their babies at birth: Pune maternal nutrition study","volume":"131","author":"Rao","year":"2001","journal-title":"J. Nutr."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.placenta.2006.01.018","article-title":"Prenatal vitamin c status is associated with placental apoptosis in normal-term human pregnancies","volume":"28","author":"Ahn","year":"2007","journal-title":"Placenta"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1111\/j.1471-0528.2012.03321.x","article-title":"Homocysteine and folate concentrations in early pregnancy and the risk of adverse pregnancy outcomes: The generation r study","volume":"119","author":"Bergen","year":"2012","journal-title":"BJOG"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.3945\/ajcn.2009.28866","article-title":"Diet quality in early pregnancy and its effects on fetal growth outcomes: The infancia y medio ambiente (childhood and environment) mother and child cohort study in spain","volume":"91","author":"Rebagliato","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1046\/j.1440-1754.2001.00684.x","article-title":"Risk factors for small-for-gestational-age babies: The auckland birthweight collaborative study","volume":"37","author":"Thompson","year":"2001","journal-title":"J. Paediatr. Child Health"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1139\/H10-010","article-title":"Dietary patterns, approaches, and multicultural perspective","volume":"35","author":"Tucker","year":"2010","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"5834","DOI":"10.3390\/nu7075253","article-title":"Major dietary patterns in relation to general and central obesity among chinese adults","volume":"7","author":"Yu","year":"2015","journal-title":"Nutrients"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1038\/sj.ejcn.1602324","article-title":"Dietary patterns and associated lifestyles in preconception, pregnancy and postpartum","volume":"60","author":"Cuco","year":"2006","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.3945\/jn.109.109579","article-title":"Women\u2019s dietary patterns change little from before to during pregnancy","volume":"139","author":"Crozier","year":"2009","journal-title":"J. Nutr."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/8\/5\/257\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:23:02Z","timestamp":1760210582000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/8\/5\/257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,28]]},"references-count":46,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2016,5]]}},"alternative-id":["nu8050257"],"URL":"https:\/\/doi.org\/10.3390\/nu8050257","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,28]]}}}