{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T16:28:09Z","timestamp":1789576089481,"version":"build-2803163510"},"reference-count":33,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T00:00:00Z","timestamp":1484956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Previous studies suggest that the prevalence of wheat\/gluten sensitivity and adherence to a gluten-free diet (GFD) are high in Latin population despite a poor diagnosis of celiac disease. However, these prevalence rates still remain unknown in most Latin American countries. Methods: A cross-sectional survey study was conducted in Santa Fe, Argentina. Results: The estimated self-reported prevalence rates were (95% Confidence Interval [CI]): self-reported gluten sensitivity (SR-GS) 7.61% (6.2\u20139.2), SR-GS currently following a GFD 1.82% (1.2\u20132.7), celiac disease 0.58% (0.3\u20131.2), wheat allergy 0.33% (0.12\u20130.84), self-reported non-celiac gluten sensitivity (SR-NCGS) 6.28% (5.1\u20137.8), SR-NCGS currently following a GFD 0.91% (0.5\u20131.6), and adherence to a GFD 6.37% (5.1\u20137.9). SR-GS was more common in women (6.0%; p &lt; 0.001) and associated with irritable bowel syndrome (p &lt; 0.001). Among the GFD followers, 71.4% were doing it for reasons other than health-related benefits and 50.6% without medical\/dietitian advice. In the non-SR-GS group, the main motivations for following a GFD were weight control and the perception that a GFD is healthier. Conclusion: In Argentina, gluten sensitivity is commonly reported and it seems that physicians\/gastroenterologists are aware of celiac disease diagnosis. Trustable information about the benefits and potential consequences of following a GFD should be given to the general population.<\/jats:p>","DOI":"10.3390\/nu9010081","type":"journal-article","created":{"date-parts":[[2017,1,23]],"date-time":"2017-01-23T10:40:33Z","timestamp":1485168033000},"page":"81","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["Prevalence of Self-Reported Gluten Sensitivity and Adherence to a Gluten-Free Diet in Argentinian Adult Population"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4985-9169","authenticated-orcid":false,"given":"Francisco","family":"Cabrera-Ch\u00e1vez","sequence":"first","affiliation":[{"name":"Nutrition Sciences Academic Unit, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, Sinaloa 80019, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gimena","family":"Dezar","sequence":"additional","affiliation":[{"name":"Facultad de Bioqu\u00edmica y Ciencias Biol\u00f3gicas, Universidad Nacional del Litoral, Santa Fe 3000, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Islas-Zamorano","sequence":"additional","affiliation":[{"name":"Nutrition Sciences Academic Unit, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, Sinaloa 80019, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Espinoza-Alderete","sequence":"additional","affiliation":[{"name":"Nutrition Sciences Academic Unit, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, Sinaloa 80019, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Vergara-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Nutrition Sciences Academic Unit, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, Sinaloa 80019, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalia","family":"Maga\u00f1a-Ordorica","sequence":"additional","affiliation":[{"name":"Nutrition Sciences Academic Unit, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, Sinaloa 80019, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8678-0447","authenticated-orcid":false,"given":"No\u00e9","family":"Ontiveros","sequence":"additional","affiliation":[{"name":"Nutrition Sciences Academic Unit, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, Sinaloa 80019, Mexico"},{"name":"Regional Program for PhD in Biotechnology, FCQB, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, Sinaloa 80019, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2017,1,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3839","DOI":"10.3390\/nu5103839","article-title":"Non-celiac gluten sensitivity: The new frontier of gluten related disorders","volume":"5","author":"Catassi","year":"2013","journal-title":"Nutrients"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Sapone, A., Bai, J.C., Ciacci, C., Dolinsek, J., Green, P.H., Hadjivassiliou, M., Kaukinen, K., Rostami, K., Sanders, D.S., and Schumann, M. (2012). Spectrum of gluten-related disorders: Consensus on new nomenclature and classification. BMC Med., 10.","DOI":"10.1186\/1741-7015-10-13"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"6036","DOI":"10.3748\/wjg.v18.i42.6036","article-title":"Celiac disease: Prevalence, diagnosism pathogenesis and tratment","volume":"18","author":"Gujral","year":"2012","journal-title":"World J. Gastroenterol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/j.jaci.2008.02.019","article-title":"The prevalence of plant food allergies: A systematic review","volume":"121","author":"Zuidmeer","year":"2008","journal-title":"J. Allergy Clin. Immunol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"723954","DOI":"10.1155\/2015\/723954","article-title":"Assessing of celiac disease and nonceliac gluten sensitivity","volume":"2015","author":"Ontiveros","year":"2015","journal-title":"Gastroenterol. Res. Pract."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1053\/j.gastro.2013.04.051","article-title":"No effects of gluten in patients with self-reported non-celiac gluten sensitivity after dietary reduction of fermentable, poorly absorbed, short-chain carbohydrates","volume":"145","author":"Biesiekierski","year":"2013","journal-title":"Gastroenterology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1084\/jem.20102660","article-title":"Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4","volume":"209","author":"Junker","year":"2012","journal-title":"J. Exp. Med."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Molina-Infante, J., and Carroccio, A. (2016). Suspected nonceliac gluten sensitivity confirmed in few patients after gluten challenge in double-blind, placebo-controlled trials. Clin. Gastroenterol. Hepatol.","DOI":"10.1016\/j.cgh.2016.08.007"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"4966","DOI":"10.3390\/nu7064966","article-title":"Diagnosis of non-celiac gluten sensitivity (NCGS): The salerno experts\u2019 criteria","volume":"7","author":"Catassi","year":"2015","journal-title":"Nutrients"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1111\/apt.13155","article-title":"Systematic review: Noncoeliac gluten sensitivity","volume":"41","author":"Santolaria","year":"2015","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"6000","DOI":"10.3390\/nu7075267","article-title":"Self-reported prevalence of symptomatic adverse reactions to gluten and adherence to gluten-free diet in an adult Mexican population","volume":"7","author":"Ontiveros","year":"2015","journal-title":"Nutrients"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Cabrera-Ch\u00e1vez, F., Granda-Restrepo, D.M., Ar\u00e1mburo-G\u00e1lvez, J.G., Franco-Aguilar, A., Maga\u00f1a-Ordorica, D., Vergara-Jim\u00e9nez, M.D.J., and Ontiveros, N. (2016). Self-reported prevalence of gluten-related disorders and adherence to gluten-free diet in Colombian adult population. Gastroenterol. Res. Pract., 2016.","DOI":"10.1155\/2016\/4704309"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"714","DOI":"10.3390\/nu8110714","article-title":"Prevalence and characterization of self-reported gluten sensitivity in The Netherlands","volume":"8","author":"Nijeboer","year":"2016","journal-title":"Nutrients"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1046\/j.1365-2036.2002.01283.x","article-title":"Evidence of poor vitamin status in coeliac patients on a gluten-free diet for 10 years","volume":"16","author":"Hallert","year":"2002","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1111\/j.1365-2036.2010.04386.x","article-title":"Evidence of high sugar intake, and low fibre and mineral intake, in the gluten-free diet","volume":"32","author":"Wild","year":"2010","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1002\/mnfr.201100515","article-title":"Dietary exposure to fumonisins and evaluation of nutrient intake in a group of adult celiac patients on a gluten-free diet","volume":"56","author":"Scarlato","year":"2012","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/01.meg.0000435546.87251.f7","article-title":"A UK study assessing the population prevalence of self-reported gluten sensitivity and referral characteristics to secondary care","volume":"26","author":"Aziz","year":"2014","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Ontiveros, N., Valdez-Meza, E.E., Vergara-Jim\u00e9nez, M.J., Canizalez-Rom\u00e1n, A., Borzutzky, F., and Cabrera-Ch\u00e1vez, F. (2016). Parent-reported prevalence of food allergy in Mexican schoolchildren: A population-based study. Allergol. Immunopathol., 44.","DOI":"10.1016\/j.aller.2016.03.003"},{"key":"ref_19","unstructured":"Dean, A.G., Sullivan, K.M., and Soe, M.M. OpenEpi: Open Source Epidemiologic Statistics for Public Health, Version, Updated 2013\/04\/06. Available online: http:\/\/www.openepi.com."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"921","DOI":"10.3109\/00365521.2013.809598","article-title":"Prevalence of gluten-free diet adherence among individuals without celiac disease in the USA: Results from the continuous national health and nutrition examination survey 2009\u20132010","volume":"48","author":"DiGiacomo","year":"2013","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1097\/MIB.0000000000000335","article-title":"A study evaluating the bidirectional relationship between inflammatory bowel disease and self-reported non-celiac gluten sensitivity","volume":"21","author":"Aziz","year":"2015","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1017\/S1368980014000652","article-title":"Motivations for avoiding wheat consumption in Australia: Results from a population survey","volume":"18","author":"Golley","year":"2015","journal-title":"Public Health Nutr."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2700","DOI":"10.1111\/j.1572-0241.2001.04124.x","article-title":"Prevalence of celiac disease in Argentina: Screening of an adult population in the La Plata Area","volume":"96","author":"Gomez","year":"2001","journal-title":"Am. J. Gastroenterol."},{"key":"ref_24","unstructured":"Ministerio de Salud Crease el Programa Nacional Para la Detecci\u00f3n y Control de Enfermedad Celiaca. Available online: http:\/\/www.msal.gob.ar\/celiacos\/pdf\/resolucion-programa.pdf."},{"key":"ref_25","unstructured":"Ministerio de Salud Resoluci\u00f3n 1365\/15: Actualiza el Monto a Cubrir por Obras Sociales y Prepagas a un Valor de $326.83 Mensuales. Available online: http:\/\/www.msal.gob.ar\/celiacos\/pdf\/Resolucion%201365.pdf."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1016\/j.jaci.2007.03.011","article-title":"Prevalence of self-reported food allergy in American adults and use of food labels","volume":"119","author":"Vierk","year":"2007","journal-title":"J. Allergy Clin. Immunol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2332\/allergolint.11-OA-0345","article-title":"Prevalence of wheat allergy in Japanese adults","volume":"61","author":"Morita","year":"2012","journal-title":"Allergol. Int."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Volta, U., Bardella, M.T., Calabr\u00f2, A., Troncone, R., and Corazza, G.R. (2014). An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity. BMC Med., 12.","DOI":"10.1186\/1741-7015-12-85"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1001\/jamainternmed.2016.5254","article-title":"Time trends in the prevalence of celiac disease and gluten-free diet in the US population: Results from the national health and nutrition examination surveys 2009\u20132014","volume":"176","author":"Kim","year":"2016","journal-title":"JAMA Intern. Med."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"68","DOI":"10.32398\/cjhp.v14i2.1876","article-title":"Motivation for gluten-free diet adherence among adults with and without a clinically diagnosed gluten-related illness","volume":"14","author":"Pember","year":"2016","journal-title":"Calif. J. Health Promot."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1017\/S0007114515002056","article-title":"Are gluten-free foods healthier than non-gluten-free foods? An evaluation of supermarket products in Australia","volume":"114","author":"Wu","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Missbach, B., Schwingshackl, L., Billmann, A., Mystek, A., Hickelsberger, M., Bauer, G., and K\u00f6nig, J. (2015). Gluten-free food database: The nutritional quality and cost of packaged gluten-free foods. PeerJ, 3.","DOI":"10.7717\/peerj.1337"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"167","DOI":"10.14409\/fabicib.v16i1.906","article-title":"Disponibilidad, costo y valor nutricional de los alimentos libres de gluten en comercios de la ciudad de santa fe","volume":"16","author":"Ortega","year":"2012","journal-title":"FABICIB"}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/9\/1\/81\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T18:26:40Z","timestamp":1760207200000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/9\/1\/81"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,21]]},"references-count":33,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1]]}},"alternative-id":["nu9010081"],"URL":"https:\/\/doi.org\/10.3390\/nu9010081","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.727237783.793551383","asserted-by":"object"}]},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,21]]}}}