{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T03:24:54Z","timestamp":1782789894555,"version":"3.54.5"},"reference-count":25,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2017,7,28]],"date-time":"2017-07-28T00:00:00Z","timestamp":1501200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>In the following review, we evaluated the current literature and evidence-based data on transdermal magnesium application and show that the propagation of transdermal magnesium is scientifically unsupported. The importance of magnesium and the positive effects of magnesium supplementation are extensively documented in magnesium deficiency, e.g., cardiovascular disease and diabetes mellitus. The effectiveness of oral magnesium supplementation for the treatment of magnesium deficiency has been studied in detail. However, the proven and well-documented oral magnesium supplementation has become questioned in the recent years through intensive marketing for its transdermal application (e.g., magnesium-containing sprays, magnesium flakes, and magnesium salt baths). In both, specialist and lay press as well as on the internet, there are increasing numbers of articles claiming the effectiveness and superiority of transdermal magnesium over an oral application. It is claimed that the transdermal absorption of magnesium in comparison to oral application is more effective due to better absorption and fewer side effects as it bypasses the gastrointestinal tract.<\/jats:p>","DOI":"10.3390\/nu9080813","type":"journal-article","created":{"date-parts":[[2017,7,28]],"date-time":"2017-07-28T10:14:34Z","timestamp":1501236874000},"page":"813","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Myth or Reality\u2014Transdermal Magnesium?"],"prefix":"10.3390","volume":"9","author":[{"given":"Uwe","family":"Gr\u00f6ber","sequence":"first","affiliation":[{"name":"Akademie f\u00fcr Mikron\u00e4hrstoffmedizin, Zweigertstr. 55, 45130 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Werner","sequence":"additional","affiliation":[{"name":"IPEV Institute for Prevention and Nutrition, Adalperostr. 37, D-85737 Ismaning, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Vormann","sequence":"additional","affiliation":[{"name":"IPEV Institute for Prevention and Nutrition, Adalperostr. 37, D-85737 Ismaning, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Kisters","sequence":"additional","affiliation":[{"name":"Akademie f\u00fcr Mikron\u00e4hrstoffmedizin, Zweigertstr. 55, 45130 Essen, Germany"},{"name":"Medizinische Klinik I, St. Anna-Hospital, 44649 Herne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2017,7,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"8199","DOI":"10.3390\/nu7095388","article-title":"Magnesium in Prevention and Therapy","volume":"7","author":"Schmidt","year":"2015","journal-title":"Nutrients"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"i3","DOI":"10.1093\/ndtplus\/sfr163","article-title":"Magnesium basics","volume":"5","author":"Ketteler","year":"2012","journal-title":"Clin. 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