{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T12:11:41Z","timestamp":1788783101978,"version":"build-2803163510"},"reference-count":23,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nurs. Rep.","Nursing Reports"],"abstract":"<jats:p>Background\/Objectives: Sarcopenia can compromise mobility and self-care. This study estimated the prevalence of an operationally defined sarcopenia phenotype among older Egyptian outpatients and described characteristics relevant to nursing assessment; Orem\u2019s Self-Care Deficit Nursing Theory framed interpretation but was not tested. Methods: This cross-sectional study consecutively recruited 320 adults aged \u226560 years from outpatient clinics at four randomly selected public hospitals in El-Beheira Governorate (August 2024\u2013January 2025). The operational definition, based on the EWGSOP 2010 framework, combined calf circumference &lt;31 cm as a pragmatic muscle-mass proxy with low handgrip strength and\/or gait speed \u2264 0.8 m\/s. Nutrition and functional independence were assessed using the BMI-based MNA-SF and Lawton-Brody IADL scale. Primary analyses comprised descriptive summaries and Wilson 95% confidence intervals; exploratory Firth-penalized logistic regression models adjusted for age and sex were sensitivity analyses. Results: The phenotype was present in 109\/320 participants (34.1%; 95% CI, 29.1\u201339.4%). Prevalence was 2.7% at ages 60\u201374 years, 16.8% at 75\u201384 years, and 91.6% at \u226585 years. Nutritional vulnerability, IADL dependence, food insecurity, polypharmacy, and recent hospitalization were descriptively more common among participants meeting the definition. Adjusted models retained several associations but yielded an unstable reversed nutritional estimate and wide confidence intervals. Conclusions: The operational phenotype identified a clinically vulnerable outpatient subgroup relevant to nursing and interdisciplinary assessment. The proxy-based definition, clinic sampling, extreme age imbalance, and cross-sectional design preclude confirmation of sarcopenia and independent-association, prognostic, or causal inference.<\/jats:p>","DOI":"10.3390\/nursrep16090326","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:30:46Z","timestamp":1788777046000},"page":"326","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Operationally Defined Sarcopenia Phenotype Among Older Egyptian Outpatients: A Descriptive Cross-Sectional Study"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2762-3350","authenticated-orcid":false,"given":"Fatma Magdi","family":"Ibrahim","sequence":"first","affiliation":[{"name":"Faculty of Nursing, Mansoura University, Mansoura 35516, Egypt"},{"name":"RAK College of Nursing, RAK Medical and Health Sciences University, Ras Al Khaimah P.O. Box 11172, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"101883","DOI":"10.1016\/j.arr.2023.101883","article-title":"An elusive consensus definition of sarcopenia impedes research and clinical treatment: A narrative review","volume":"86","author":"Coletta","year":"2023","journal-title":"Ageing Res. Rev."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: Revised European consensus on definition and diagnosis","volume":"48","author":"Bahat","year":"2019","journal-title":"Age Ageing"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.gerinurse.2024.09.018","article-title":"Prevalence and risk factors for sarcopenia in active community-dwelling older adults according to the EWGSOP2 criteria","volume":"60","year":"2024","journal-title":"Geriatr. Nurs."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/jcsm.12783","article-title":"Global prevalence of sarcopenia and severe sarcopenia: A systematic review and meta-analysis","volume":"13","author":"Balntzi","year":"2022","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Tan You Mei, C., Seah Si Ying, S., Lim Yanshan, D., Koh, S.V., Karthikeyan, G., Xia Jiawen, O., Low, X.L., Quek, H.Y., Ong Shuyi, A., and Low, L.L. (2024). Prevalence and factors associated with sarcopenia among older adults in a post-acute hospital in Singapore. PLoS ONE, 19.","DOI":"10.1371\/journal.pone.0291702"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1159\/000549808","article-title":"Prevalence and factors associated with sarcopenia in community-dwelling older adults: A systematic review and meta-analysis","volume":"72","author":"Wang","year":"2026","journal-title":"Gerontology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis","volume":"39","author":"Baeyens","year":"2010","journal-title":"Age Ageing"},{"key":"ref_8","unstructured":"Orem, D.E. (2001). Nursing: Concepts of Practice, Mosby. [6th ed.]."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"von Elm, E., Altman, D.G., Egger, M., Pocock, S.J., G\u00f8tzsche, P.C., Vandenbroucke, J.P. (2007). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies. PLoS Med., 4.","DOI":"10.1371\/journal.pmed.0040296"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1093\/ageing\/afr051","article-title":"A review of the measurement of grip strength in clinical and epidemiological studies: Towards a standardised approach","volume":"40","author":"Roberts","year":"2011","journal-title":"Age Ageing"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1001\/jama.2010.1923","article-title":"Gait speed and survival in older adults","volume":"305","author":"Studenski","year":"2011","journal-title":"JAMA"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1046\/j.1532-5415.2003.51362.x","article-title":"Sarcopenia, calf circumference, and physical function of elderly women: A cross-sectional study","volume":"51","author":"Rolland","year":"2003","journal-title":"J. Am. Geriatr. Soc."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","article-title":"Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment","volume":"21","author":"Chen","year":"2020","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"ref_14","first-page":"8","article-title":"Prevalence of malnutrition in recently hospitalized elderly in Cairo using a valid and reliable short form of Arabic version of Mini Nutritional Assessment (MNA-SF-A)","volume":"9","year":"2012","journal-title":"Middle East J. Age Ageing"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1007\/s12603-009-0214-7","article-title":"Validation of the Mini Nutritional Assessment Short-Form (MNA-SF): A practical tool for identification of nutritional status","volume":"13","author":"Kaiser","year":"2009","journal-title":"J. Nutr. Health Aging"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"104018","DOI":"10.1016\/j.archger.2020.104018","article-title":"Overestimated functional dependency in older patients: Can we blame gender difference, unneeded assistance, or assessment tools?","volume":"88","author":"Rasheedy","year":"2020","journal-title":"Arch. Gerontol. Geriatr."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/biomet\/80.1.27","article-title":"Bias reduction of maximum likelihood estimates","volume":"80","author":"Firth","year":"1993","journal-title":"Biometrika"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1002\/sim.1047","article-title":"A solution to the problem of separation in logistic regression","volume":"21","author":"Heinze","year":"2002","journal-title":"Stat. Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1007\/s41999-021-00463-x","article-title":"Prevalence of sarcopenia and associated factors in older adults attending a day hospital service in Ireland","volume":"12","author":"Connolly","year":"2021","journal-title":"Eur. Geriatr. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/jcsm.12651","article-title":"Sarcopenia: Prevalence, associated factors, and the risk of mortality and disability in Japanese older adults","volume":"12","author":"Kitamura","year":"2021","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"389","DOI":"10.5720\/kjcn.2025.00360","article-title":"Dietary factors and nutritional guidelines for sarcopenia in older adults: A narrative review","volume":"30","author":"Heo","year":"2025","journal-title":"Korean J. Community Nutr."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Zhao, R., Dong, Y., Zheng, Q., and Yao, J. (2025). Exercise and nutrition strategies for sarcopenia in older adults: Evidence from a network meta-analysis based on EWGSOP and AWGS criteria. Front. Nutr., 12.","DOI":"10.3389\/fnut.2025.1685014"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1002\/jcsm.13190","article-title":"Sarcopenia is associated with a greater risk of polypharmacy and number of medications: A systematic review and meta-analysis","volume":"14","author":"Prokopidis","year":"2023","journal-title":"J. Cachexia Sarcopenia Muscle"}],"container-title":["Nursing Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2039-4403\/16\/9\/326\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T11:25:08Z","timestamp":1788780308000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-4403\/16\/9\/326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,7]]},"references-count":23,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["nursrep16090326"],"URL":"https:\/\/doi.org\/10.3390\/nursrep16090326","relation":{},"ISSN":["2039-4403"],"issn-type":[{"value":"2039-4403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,7]]}}}