{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T23:14:26Z","timestamp":1793229266287,"version":"4.5.0"},"reference-count":81,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T00:00:00Z","timestamp":1619049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the Center of Excellence on Agricultural Biotechnology, Science and Technology Postgraduate Education and Research Development Office, Office of Higher Education Commission, Ministry of Higher Education, Science, Research and Innovation. (AG-BIO\/PERDO-CHE","award":["AG-BIO\/61-003-011"],"award-info":[{"award-number":["AG-BIO\/61-003-011"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>(1) Background: Bartonella spp. are Gram-negative, facultative, intracellular bacteria transmitted by hematophagous insects. Several species cause zoonotic diseases such as cat-scratch disease. Bartonella henselae and Bartonella clarridgeiae are the main species found in Thailand, however, there have been few studies on Bartonella spp. In addition, the hematological evaluation of Bartonella-infected animals is limited in Thailand. The aims of this study were prevalence investigation and hematological evaluation of Bartonella-infected dogs and cats residing in Bangkok, Thailand. (2) Methods: In total, 295 dogs and 513 cats were molecularly evaluated to detect Bartonella spp. using PCR with primers targeting the partial gltA, rpoB, ftsZ, ribC, and groEL genes. In total, 651 domestic animals were evaluated for hematological parameters compared between Bartonella-positive and Bartonella-negative animals. (3) Results: Overall, the prevalence of Bartonella spp. was 1.61% which was found only in free-ranging cats (2.83%). Bartonella henselae and B. clarridgeiae were confirmed from a concatenated phylogenetic tree of partial gltA and ribC genes, with 100% bootstrapping replication. For other housekeeping gene sequences, mixed infection was expected from the amplicons of rpoB, ftsZ, and groEL. Importantly, the mean corpuscular volume (MCV) was significantly increased in Bartonella-positive cats. (4) Conclusions: We suggest that B. henselae and B. clarridgeiae are important species and are still circulating in domestic animals, especially cats. The evaluation of blood parameters, especially a raised MCV, should be of concern in Bartonella infection in asymptomatic cats. Additionally, the knowledge of how to prevent Bartonella-related diseases should be promoted with people in at-risk situations.<\/jats:p>","DOI":"10.3390\/pathogens10050503","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T13:59:14Z","timestamp":1619099954000},"page":"503","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Molecular Detection of Bartonella spp. and Hematological Evaluation in Domestic Cats and Dogs from Bangkok, Thailand"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0432-0998","authenticated-orcid":false,"given":"Phirabhat","family":"Saengsawang","sequence":"first","affiliation":[{"name":"Center for Agricultural Biotechnology, Kamphaeng Saen Campus, Kasetsart University, Nakhon Pathom 73140, Thailand"},{"name":"Center of Excellence on Agricultural Biotechnology (AG-BIO\/PERDO-CHE), Bangkok 10900, Thailand"},{"name":"Akkhraratchakumari Veterinary College, Walailak University, Nakhon Si Thammarat 80161, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunn","family":"Kaewmongkol","sequence":"additional","affiliation":[{"name":"Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5982-4811","authenticated-orcid":false,"given":"Tawin","family":"Inpankaew","sequence":"additional","affiliation":[{"name":"Center for Agricultural Biotechnology, Kamphaeng Saen Campus, Kasetsart University, Nakhon Pathom 73140, Thailand"},{"name":"Center of Excellence on Agricultural Biotechnology (AG-BIO\/PERDO-CHE), Bangkok 10900, Thailand"},{"name":"Department of Parasitology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,4,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cimid.2012.10.004","article-title":"Ctenocephalides felis an in vitro potential vector for five Bartonella species","volume":"36","author":"Bouhsira","year":"2013","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1196\/annals.1374.041","article-title":"Arthropod-borne diseases in homeless","volume":"1078","author":"Brouqui","year":"2006","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.actatropica.2017.11.003","article-title":"The epidemic typhus and trench fever are risk for public health due to increased migration in southeast of Turkey","volume":"178","author":"Ulutasdemir","year":"2018","journal-title":"Acta Trop."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Battisti, J.M., Lawyer, P.G., and Minnick, M.F. (2015). Colonization of Lutzomyia verrucarum and Lutzomyia longipalpis sand flies (Diptera: Psychodidae) by Bartonella bacilliformis, the etiologic agent of Carri\u00f3n\u2019s disease. PLoS Negl. Trop. Dis., 9.","DOI":"10.1371\/journal.pntd.0004128"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Wechtaisong, W., Bonnet, S.I., Lien, Y.-Y., Chuang, S.-T., and Tsai, Y.-L. (2020). Transmission of Bartonella henselae within Rhipicephalus sanguineus: Data on the potential vector role of the tick. PLoS Negl. Trop. Dis., 14.","DOI":"10.1371\/journal.pntd.0008664"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"313","DOI":"10.14411\/fp.2006.039","article-title":"Bartonella infections in fleas (Siphonaptera: Pulicidae) and lack of bartonellae in ticks (Acari: Ixodidae) from Hungary","volume":"53","author":"Tornyai","year":"2006","journal-title":"Folia Parasitol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10493-019-00380-6","article-title":"The role of juvenile Dermacentor reticulatus ticks as vectors of microorganisms and the problem of \u201cmeal contamination\u201d","volume":"78","author":"Mierzejewska","year":"2019","journal-title":"Exp. Appl. Acarol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e811","DOI":"10.1016\/j.ijid.2013.02.016","article-title":"Treatment outcomes of human bartonellosis: A systematic review and meta-analysis","volume":"17","author":"Prutsky","year":"2013","journal-title":"Int. J. Infect. Dis."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.vetmic.2009.11.011","article-title":"Bartonellosis","volume":"140","author":"Guptill","year":"2010","journal-title":"Vet. Microbiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1051\/vetres:2005009","article-title":"Factors associated with the rapid emergence of zoonotic Bartonella infections","volume":"36","author":"Boulouis","year":"2005","journal-title":"Vet. Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"431","DOI":"10.3389\/fcimb.2018.00431","article-title":"Molecular mechanisms of Bartonella and mammalian erythrocyte interactions: A review","volume":"8","author":"Deng","year":"2018","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Yuan, C., Zhu, C., Wu, Y., Pan, X., and Hua, X. (2011). Bacteriological and molecular identification of Bartonella species in cats from different regions of China. PLoS Negl. Trop. Dis., 5.","DOI":"10.1371\/journal.pntd.0001301"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"105056","DOI":"10.1016\/j.actatropica.2019.105056","article-title":"Molecular detection and characterization of Bartonella spp. in pet cats and dogs in Shenzhen, China","volume":"197","author":"Zhang","year":"2019","journal-title":"Acta Trop."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1186\/s13071-018-3152-6","article-title":"Bartonella infections in cats and dogs including zoonotic aspects","volume":"11","author":"Breitschwerdt","year":"2018","journal-title":"Parasit. Vectors"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1365-2672.2010.04679.x","article-title":"Bartonellosis, an increasingly recognized zoonosis","volume":"109","author":"Chomel","year":"2010","journal-title":"J. Appl. Microbiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"389","DOI":"10.3201\/eid1203.050931","article-title":"Bartonella spp. in pets and effect on human health","volume":"12","author":"Chomel","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1016\/j.rvsc.2012.03.015","article-title":"Prevalence of Bartonella species, hemoplasmas, and Rickettsia felis DNA in blood and fleas of cats in Bangkok, Thailand","volume":"93","author":"Assarasakorn","year":"2012","journal-title":"Res. Vet. Sci."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.actatropica.2019.02.026","article-title":"Bartonella henselae and Bartonella clarridgeiae infection, hematological changes and associated factors in domestic cats and dogs from an Atlantic rain forest area, Brazil","volume":"193","author":"Campos","year":"2019","journal-title":"Acta Trop."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.ttbdis.2014.03.011","article-title":"Arthropod-borne pathogens circulating in free-roaming domestic cats in a zoo environment in Brazil","volume":"5","author":"Henrique","year":"2014","journal-title":"Ticks Tick Borne Dis."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ttbdis.2017.08.013","article-title":"Molecular detection of vector-borne pathogens in Greek cats","volume":"9","author":"Mylonakis","year":"2018","journal-title":"Ticks Tick Borne Dis."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.rvsc.2009.11.005","article-title":"Molecular detection of Bartonella henselae and Bartonella clarridgeiae in clinical samples of pet cats from Southern Italy","volume":"88","author":"Pennisi","year":"2010","journal-title":"Res. Vet. Sci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.rvsc.2011.07.013","article-title":"Occurrence of Bartonella henselae types I and II in Central Italian domestic cats","volume":"93","author":"Ebani","year":"2012","journal-title":"Res. Vet. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.vetmic.2010.08.012","article-title":"Combined MLST and AFLP typing of Bartonella henselae isolated from cats reveals new sequence types and suggests clonal evolution","volume":"148","author":"Mietze","year":"2011","journal-title":"Vet. Microbiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.cimid.2011.09.002","article-title":"Bartonellae in animals and vectors in New Caledonia","volume":"34","author":"Mediannikov","year":"2011","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.jfms.2009.12.015","article-title":"Feline immunodeficiency virus, feline leukemia virus and Bartonella species in stray cats on St Kitts, West Indies","volume":"12","author":"Kelly","year":"2010","journal-title":"J. Feline Med. Surg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.jfms.2009.10.007","article-title":"Association of Bartonella species, feline calicivirus, and feline herpesvirus 1 infection with gingivostomatitis in cats","volume":"12","author":"Dowers","year":"2010","journal-title":"J. Feline Med. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.jfms.2010.07.003","article-title":"Bartonella species, feline herpesvirus-1, and Toxoplasma gondii PCR assay results from blood and aqueous humor samples from 104 cats with naturally occurring endogenous uveitis","volume":"12","author":"Powell","year":"2010","journal-title":"J. Feline Med. Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jfms.2006.05.003","article-title":"Prevalence of Mycoplasma haemofelis, \u2018Candidatus Mycoplasma haemominutum\u2019, Bartonella species, Ehrlichia species, and Anaplasma phagocytophilum DNA in the blood of cats with anemia","volume":"9","author":"Ishak","year":"2007","journal-title":"J. Feline Med. Surg."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jfms.2005.08.003","article-title":"Prevalence of Bartonella species, haemoplasma species, Ehrlichia species, Anaplasma phagocytophilum, and Neorickettsia risticii DNA in the blood of cats and their fleas in the United States","volume":"8","author":"Lappin","year":"2006","journal-title":"J. Feline Med. Surg."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Alanazi, A.D., Alouffi, A.S., Alyousif, M.S., Alshahrani, M.Y., Abdullah, H.H.A.M., Abdel-Shafy, S., Calvani, N.E., Ansari-Lari, M., Sazmand, A., and Otranto, D. (2021). Molecular survey of vector-borne pathogens of dogs and cats in two regions of Saudi Arabia. Pathogens, 10.","DOI":"10.3390\/pathogens10010025"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jfms.2008.06.005","article-title":"Prevalence of Bartonella species antibodies and Bartonella species DNA in the blood of cats with and without fever","volume":"11","author":"Lappin","year":"2009","journal-title":"J. Feline Med. Surg."},{"key":"ref_32","first-page":"1","article-title":"Evidence of Bartonella spp., Rickettsia spp. and Anaplasma phagocytophilum in domestic, shelter and stray cat blood and fleas, Portugal","volume":"15","author":"Alves","year":"2009","journal-title":"Microbiol. Infect. Dis."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1046\/j.1469-0691.2002.00434.x","article-title":"Lack of correlation between Bartonella DNA detection within fleas, serological results, and results of blood culture in a Bartonella-infected stray cat population","volume":"8","author":"Davoust","year":"2002","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0378-1135(01)00304-2","article-title":"Epidemiology of Bartonella infection in domestic cats in France","volume":"80","author":"Gurfield","year":"2001","journal-title":"Vet. Microbiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.vetpar.2017.01.019","article-title":"Feline and canine leishmaniosis and other vector-borne diseases in the Aeolian Islands: Pathogen and vector circulation in a confined environment","volume":"236","author":"Otranto","year":"2017","journal-title":"Vet. Parasitol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1469-0691.2008.02203.x","article-title":"Serological and molecular detection of Bartonella spp. in humans, cats and dogs from northern Sardinia, Italy","volume":"15","author":"Zobba","year":"2009","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.ttbdis.2015.11.003","article-title":"Molecular detection of vector-borne pathogens in wild and domestic carnivores and their ticks at the human-wildlife interface","volume":"7","author":"Proboste","year":"2016","journal-title":"Ticks Tick Borne Dis."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.jfms.2011.03.006","article-title":"Prevalence of Bartonella species, haemoplasmas and Toxoplasma gondii in cats in Scotland","volume":"13","author":"Bennett","year":"2011","journal-title":"J. Feline Med. Surg."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.jfms.2010.02.003","article-title":"Prevalence of selected infectious agents in cats in Ireland","volume":"12","author":"Juvet","year":"2010","journal-title":"J. Feline Med. Surg."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.ttbdis.2016.05.001","article-title":"Molecular detection of Anaplasma platys, Ehrlichia canis, Hepatozoon canis and Rickettsia monacensis in dogs from Maio Island of Cape Verde archipelago","volume":"7","author":"Lauzi","year":"2016","journal-title":"Ticks Tick Borne Dis."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.vetpar.2007.11.008","article-title":"Prevalence of Ehrlichia canis, Anaplasma platys, Babesia canis vogeli, Hepatozoon canis, Bartonella vinsonii berkhoffii, and Rickettsia spp. in dogs from Grenada","volume":"151","author":"Yabsley","year":"2008","journal-title":"Vet. Parasitol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.jvc.2018.04.006","article-title":"Polymerase chain reaction detection of Bartonella spp. in dogs from Spain with blood culture-negative infectious endocarditis","volume":"20","author":"Roura","year":"2018","journal-title":"J. Vet. Cardiol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jvc.2019.11.005","article-title":"Prevalence of Bartonella sp. in United States military working dogs with infectious endocarditis: A retrospective case\u2013control study","volume":"27","author":"Davis","year":"2020","journal-title":"J. Vet. Cardiol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.vetpar.2013.10.017","article-title":"Flea species infesting dogs in Florida and Bartonella spp. prevalence rates","volume":"199","author":"Yore","year":"2014","journal-title":"Vet. Parasitol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"105277","DOI":"10.1016\/j.actatropica.2019.105277","article-title":"Detection of Bartonella infection in pet dogs from Manila, the Philippines","volume":"205","author":"Singer","year":"2020","journal-title":"Acta Trop."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.vetmic.2010.05.017","article-title":"Enrichment culture and molecular identification of diverse Bartonella species in stray dogs","volume":"146","author":"Bai","year":"2010","journal-title":"Vet. Microbiol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.bjid.2017.02.002","article-title":"Bartonella species pathogenic for humans infect pets, free-ranging wild mammals and their ectoparasites in the Caatinga biome, Northeastern Brazil: A serological and molecular study","volume":"21","author":"Fontalvo","year":"2017","journal-title":"Braz. J. Infect. Dis."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/1756-3305-7-115","article-title":"Bacterial and protozoal agents of feline vector-borne diseases in domestic and stray cats from southern Portugal","volume":"7","author":"Maia","year":"2014","journal-title":"Parasit. Vectors"},{"key":"ref_49","first-page":"423","article-title":"Prevalence of Bartonella clarridgeiae and Bartonella henselae in domestic cats from France and detection of the organisms in erythrocytes by immunofluorescence","volume":"11","author":"Rolain","year":"2004","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1089\/vbz.2014.1673","article-title":"Prevalence and genetic diversity of Bartonella strains in rodents from northwestern Mexico","volume":"14","author":"Rubio","year":"2014","journal-title":"Vector Borne Zoonotic Dis."},{"key":"ref_51","first-page":"783","article-title":"Assessment of a quantitative 5\u2019 nuclease real-time polymerase chain reaction using the nicotinamide adenine dinucleotide dehydrogenase gamma subunit (nuoG) for Bartonella species in domiciled and stray cats in Brazil","volume":"18","author":"Dumler","year":"2015","journal-title":"J. Feline Med. Surg."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1128\/CMR.05009-11","article-title":"Intruders below the radar: Molecular pathogenesis of Bartonella spp.","volume":"25","author":"Harms","year":"2012","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1186\/s13071-017-2483-z","article-title":"Prevalence of Bartonella spp. by culture, PCR and serology, in veterinary personnel from Spain","volume":"10","author":"Oteo","year":"2017","journal-title":"Parasit. Vectors"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1177\/104063870101300406","article-title":"Evaluation and use of a nested polymerase chain reaction assay in cats experimentally infected with Bartonella henselae genotype I and Bartonella henselae genotype II","volume":"13","author":"Roy","year":"2001","journal-title":"J. Vet. Diagn. Investig."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1111\/jvim.12094","article-title":"Phylogenetic diversity of bacteria isolated from sick dogs using the BAPGM enrichment culture platform","volume":"27","author":"Davenport","year":"2013","journal-title":"J. Vet. Intern. Med."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.mimet.2007.08.006","article-title":"Identification of bacteria from clinical samples using Bartonella alpha-Proteobacteria growth medium","volume":"71","author":"Cadenas","year":"2007","journal-title":"J. Microbiol. Methods"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"593","DOI":"10.4269\/ajtmh.1999.60.593","article-title":"Bartonella henselae and Bartonella clarridgeiae infection in domestic cats from The Philippines","volume":"60","author":"Chomel","year":"1999","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1128\/CDLI.6.1.41-44.1999","article-title":"Prevalence of Bartonella henselae and Bartonella clarridgeiae in an urban Indonesian cat population","volume":"6","author":"Marston","year":"1999","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"783","DOI":"10.4269\/ajtmh.2001.65.783","article-title":"Prevalence of Bartonella species and 16s rRNA gene types of Bartonella henselae from domestic cats in Thailand","volume":"65","author":"Maruyama","year":"2001","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"931","DOI":"10.4269\/ajtmh.2011.10-0634","article-title":"Molecular detection of Rickettsia felis, Bartonella henselae, and B. clarridgeiae in fleas from domestic dogs and cats in Malaysia","volume":"85","author":"Mokhtar","year":"2011","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"473","DOI":"10.3201\/eid2003.131059","article-title":"Infective endocarditis in northeastern Thailand","volume":"20","author":"Watt","year":"2014","journal-title":"Emerg. Infect. Dis."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"989","DOI":"10.3201\/eid1806.111750","article-title":"Bartonella vinsonii subsp. arupensis in humans, Thailand","volume":"18","author":"Bai","year":"2012","journal-title":"Emerg. Infect. Dis."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"100001","DOI":"10.1016\/j.crpvbd.2020.100001","article-title":"Canine and feline vector-borne diseases of zoonotic concern in Southeast Asia","volume":"1","author":"Nguyen","year":"2021","journal-title":"Curr. Res. Parasitol. Vector-Borne Dis."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"e667","DOI":"10.1016\/j.ijid.2009.11.011","article-title":"Fleas and flea-borne diseases","volume":"14","author":"Bitam","year":"2010","journal-title":"Int. J. Infect. Dis."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.ijpara.2019.01.001","article-title":"Out-of-Africa, human-mediated dispersal of the common cat flea, Ctenocephalides felis: The hitchhiker\u2019s guide to world domination","volume":"49","author":"Lawrence","year":"2019","journal-title":"Int. J. Parasitol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1093\/jmedent\/35.5.625","article-title":"Experimental infection of domestic cats with Bartonella henselae by inoculation of Ctenocephalides felis (Siphonaptera: Pulicidae) feces","volume":"35","author":"Foil","year":"1998","journal-title":"J. Med. Entomol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0966-842X(03)00143-4","article-title":"Gene-sequence-based criteria for species definition in bacteriology: The Bartonella paradigm","volume":"11","author":"Zeaiter","year":"2003","journal-title":"Trends Microbiol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1128\/jcm.33.7.1797-1803.1995","article-title":"Differentiation of Bartonella-like isolates at the species level by PCR-restriction fragment length polymorphism in the citrate synthase gene","volume":"33","author":"Norman","year":"1995","journal-title":"J. Clin. Microbiol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1128\/JCM.41.3.1069-1072.2003","article-title":"Detection and identification of Bartonella species pathogenic for humans by PCR amplification targeting the riboflavin synthase gene (ribC)","volume":"41","author":"Johnson","year":"2003","journal-title":"J. Clin. Microbiol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.2217\/fmb.13.77","article-title":"Natural history of Bartonella-infecting rodents in light of new knowledge on genomics, diversity and evolution","volume":"8","author":"Buffet","year":"2013","journal-title":"Future Microbiol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"101504","DOI":"10.1016\/j.cimid.2020.101504","article-title":"Molecular detection and phylogenetic analysis of \u2018Candidatus Bartonella merieuxii\u2019 in dogs and its effect on hematologic parameters","volume":"72","author":"Samsami","year":"2020","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"108404","DOI":"10.1016\/j.vetmic.2019.108404","article-title":"\u201cCandidatus Bartonella dromedarii\u201d in the dromedary camels of Iran: Molecular investigation, phylogenetic analysis, hematological findings, and acute-phase proteins quantitation","volume":"237","author":"Ghaemi","year":"2019","journal-title":"Vet. Microbiol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1574-6968.2000.tb08884.x","article-title":"Contact-dependent hemolytic activity distinct from deforming activity of Bartonella bacilliformis","volume":"182","author":"Hendrix","year":"2000","journal-title":"FEMS Microbiol. Lett."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"591","DOI":"10.3855\/jidc.8152","article-title":"Bartonella spp. and hematological changes in privately owned domestic cats from Rio de Janeiro, Brazil","volume":"11","author":"Souza","year":"2017","journal-title":"J. Infect. Dev. Ctries."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1017\/S003118201600247X","article-title":"Prevalence, hematological findings and genetic diversity of Bartonella spp. in domestic cats from Valdivia, Southern Chile","volume":"144","author":"Walker","year":"2017","journal-title":"Parasitology"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1051\/vetres\/2009011","article-title":"Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors","volume":"40","author":"Chomel","year":"2009","journal-title":"Vet. Res."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1574-6968.2000.tb09205.x","article-title":"Hemin-dependent growth and hemin binding of Bartonella henselae","volume":"189","author":"Sander","year":"2000","journal-title":"FEMS Microbiol. Lett."},{"key":"ref_78","unstructured":"Beugnet, F., and Halos, L. (2015). Parasitoses & Vector Borne Diseases of Cats, Merial."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1128\/JCM.39.2.430-437.2001","article-title":"Use of rpoB gene analysis for detection and identification of Bartonella species","volume":"39","author":"Renesto","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"3641","DOI":"10.1128\/JCM.40.10.3641-3647.2002","article-title":"Genetic classification and differentiation of Bartonella species based on comparison of partial ftsZ gene sequences","volume":"40","author":"Zeaiter","year":"2002","journal-title":"J. Clin. Microbiol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1099\/00207713-52-1-165","article-title":"Phylogenetic classification of Bartonella species by comparing groEL sequences","volume":"52","author":"Zeaiter","year":"2002","journal-title":"Int. J. Syst. Evol. Microbiol."}],"container-title":["Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-0817\/10\/5\/503\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:51:28Z","timestamp":1760161888000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-0817\/10\/5\/503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,22]]},"references-count":81,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5]]}},"alternative-id":["pathogens10050503"],"URL":"https:\/\/doi.org\/10.3390\/pathogens10050503","relation":{},"ISSN":["2076-0817"],"issn-type":[{"value":"2076-0817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,22]]}}}