{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:37:37Z","timestamp":1760243857379,"version":"build-2065373602"},"reference-count":0,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2011,9,29]],"date-time":"2011-09-29T00:00:00Z","timestamp":1317254400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Infection ranks alongside cardiovascular disease as the major cause of human death across the world. Word Health Organization data for 2002 shows that 26% of all deaths, almost 15 million in number, were due to infectious disease with HIV\/AIDS, TB and malaria being the top three responsible infections. A significant proportion of these deaths were due to lower respiratory infections and diarrheal diseases in children. The worldwide morbidity associated with infectious disease is incalculable. When considered along with the consequences of infection in animals, it is hard to imagine any other disease that has such a significant impact on our lives\u2015on health systems, on agriculture and on world economics.\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tOur understanding of the agents responsible for infections\u2015bacteria, fungi, parasites, prions and viruses\u2015has an interesting history that heralds the great developments in modern biology and demonstrates how an understanding of disease pathogenesis can lead to successful prophylactic and therapeutic interventions. Van Leeuwenhoek\u2019s first observation of bacteria under the light microscope, John Snow\u2019s investigations tracing the source of a cholera epidemic in Victorian London\u2019s Soho and Pasteur\u2019s vaccines for rabies and anthrax contributed to an acceptance of the germ theory of disease and to the rational, scientific application of this knowledge to develop innovative disease control measures ranging from hygienic practices to antibiotics. [...]<\/jats:p>","DOI":"10.3390\/pathogens1010001","type":"journal-article","created":{"date-parts":[[2011,9,29]],"date-time":"2011-09-29T11:34:46Z","timestamp":1317296086000},"page":"1-2","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pathogens: A New Open Access Journal Serving All Those Interested in Infectious Disease"],"prefix":"10.3390","volume":"1","author":[{"given":"Lawrence S.","family":"Young","sequence":"first","affiliation":[{"name":"College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2011,9,29]]},"container-title":["Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-0817\/1\/1\/1\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:57:33Z","timestamp":1760219853000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-0817\/1\/1\/1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,29]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,9]]}},"alternative-id":["pathogens1010001"],"URL":"https:\/\/doi.org\/10.3390\/pathogens1010001","relation":{},"ISSN":["2076-0817"],"issn-type":[{"type":"electronic","value":"2076-0817"}],"subject":[],"published":{"date-parts":[[2011,9,29]]}}}