{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:31:22Z","timestamp":1782477082971,"version":"3.54.5"},"reference-count":33,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T00:00:00Z","timestamp":1647302400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Parasitic infections (PIs) are among the most frequent infectious diseases globally. Previous studies reported discrepant results regarding the prevalence of PIs in internationally adopted children (IAC). Data from IAC referred to our paediatric university hospital in 2009\u20132021 were collected to evaluate the frequency of PIs by the use of stool microscopic examination, antigen assays for Giardia lamblia and Cryptosporidium parvum, and serological tests for Toxocara canis, Strongyloides stercoralis, Schistosoma mansoni, Echinococcus spp., Taenia solium, and Trypanosoma cruzi. Uni- and multivariate logistic regression analyses were performed to evaluate risk factors for PIs and eosinophilia. The proportion of IAC with at least one positive test was 26.83% (640\/2385); 2.13% (n = 51) had positive tests for 2 or 3 parasites. A positive assay for helminthic infection was retrieved in 11.07% of children (n = 264), and 17.86% (n = 426) presented with eosinophilia. The most common positive tests were anti-Toxocara canis antibodies (n = 312; 13.8%), followed by positive stool antigen for Giardia lamblia (n = 290; 12.16%), and positive microscopic stool examination for Blastocystis hominis (n = 76; 3.19%). A statistically significant association was found between PIs and region of origin (children from Latin America and Africa were more likely to present PIs than children from Eastern Europe), age 5\u201314 years, and eosinophilia. No significant association was observed between PIs and gender, vitamin D deficiency, or anemia. In conclusion, PIs are relevant in IAC and an accurate protocol is needed to evaluate IAC once they arrive in their adoptive country.<\/jats:p>","DOI":"10.3390\/pathogens11030354","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T02:56:20Z","timestamp":1647312980000},"page":"354","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Parasitic Infections in Internationally Adopted Children: A Twelve-Year Retrospective Study"],"prefix":"10.3390","volume":"11","author":[{"given":"Elena","family":"Chiappini","sequence":"first","affiliation":[{"name":"Pediatric Infectious Disease Unit, Anna Meyer Children\u2019s University Hospital, 50100 Florence, Italy"},{"name":"Department of Health Sciences, University of Florence, 50100 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Paba","sequence":"additional","affiliation":[{"name":"Pediatric Infectious Disease Unit, Anna Meyer Children\u2019s University Hospital, 50100 Florence, Italy"},{"name":"Department of Health Sciences, University of Florence, 50100 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matilde","family":"Bestetti","sequence":"additional","affiliation":[{"name":"Pediatric Infectious Disease Unit, Anna Meyer Children\u2019s University Hospital, 50100 Florence, Italy"},{"name":"Department of Health Sciences, University of Florence, 50100 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Galli","sequence":"additional","affiliation":[{"name":"Pediatric Infectious Disease Unit, Anna Meyer Children\u2019s University Hospital, 50100 Florence, Italy"},{"name":"Department of Health Sciences, University of Florence, 50100 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1097\/INF.0000000000002399","article-title":"Intestinal Parasitic Infections in Internationally Adopted Children: A 10-Year Retrospective Study","volume":"38","author":"Buonsenso","year":"2019","journal-title":"Pediatr. 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