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Hepatic dysfunction has been seen in patients with COVID-19 and could be related to a viral cytopathic effect, an exacerbated immune reaction, or drug-induced liver damage. Currently, routine modification of immunosuppressive therapy in patients with autoimmune hepatitis (AIH) before and after SARS-CoV-2 infection remains an important topic to be discussed. However, there is little evidence about this thematic to support any recommendation. Here, we described a case report in which the use of an immunosuppressive drug by a patient with diagnosed AIH might have influenced the COVID-19 clinical course with altered laboratory hematological and biochemical parameters during infection.<\/jats:p>","DOI":"10.3390\/pathogens11091054","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T01:35:10Z","timestamp":1663292110000},"page":"1054","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient"],"prefix":"10.3390","volume":"11","author":[{"given":"Vanessa Duarte","family":"da Costa","sequence":"first","affiliation":[{"name":"Brazilian Reference Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilian Jean","family":"Wiggers","sequence":"additional","affiliation":[{"name":"Service of Gastroenterology, Hepatology and Liver Transplantation, Hospital Nossa Senhora das Gra\u00e7as, R. Alcides Munhoz, 433, Merc\u00eas, Curitiba 80810-040, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5422-557X","authenticated-orcid":false,"given":"Claudia Alexandra Pontes","family":"Ivantes","sequence":"additional","affiliation":[{"name":"Service of Gastroenterology, Hepatology and Liver Transplantation, Hospital Nossa Senhora das Gra\u00e7as, R. Alcides Munhoz, 433, Merc\u00eas, Curitiba 80810-040, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0943-5356","authenticated-orcid":false,"given":"Rodrigo Jardim Monteiro","family":"da Fonseca","sequence":"additional","affiliation":[{"name":"Computational and Systems Biology Laboratory, Graduate Program in Biodiversity and Health, Oswaldo Cruz Institute, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto Mart\u00edn Rivera","family":"D\u00e1vila","sequence":"additional","affiliation":[{"name":"Computational and Systems Biology Laboratory, Graduate Program in Biodiversity and Health, Oswaldo Cruz Institute, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5340-8697","authenticated-orcid":false,"given":"Otacilio C.","family":"Moreira","sequence":"additional","affiliation":[{"name":"Molecular Virology Laboratory, Oswaldo Cruz Institute, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz Iandra da Silva","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Molecular Virology Laboratory, Oswaldo Cruz Institute, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa Salete","family":"de Paula","sequence":"additional","affiliation":[{"name":"Molecular Virology Laboratory, Oswaldo Cruz Institute, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Lima","family":"da Silva","sequence":"additional","affiliation":[{"name":"Brazilian Reference Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alanna Calheiros","family":"Santos","sequence":"additional","affiliation":[{"name":"Brazilian Reference Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7644-8969","authenticated-orcid":false,"given":"Livia Melo","family":"Villar","sequence":"additional","affiliation":[{"name":"Brazilian Reference Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/j.jhep.2021.01.021","article-title":"SARS-CoV-2 infection in patients with autoimmune hepatitis","volume":"74","author":"Marjot","year":"2021","journal-title":"J. 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