{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T01:15:05Z","timestamp":1770340505373,"version":"3.49.0"},"reference-count":27,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T00:00:00Z","timestamp":1668556800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Mexico is an endemic region for dengue virus (DENV). The increase in this disease coincides with outbreaks of COVID-19, both of which are single-stranded positive RNA viruses. These characteristics make it difficult to distinguish each disease because they share clinical and laboratory features, which can consequently result in misdiagnoses. This is why the use of precision confirmatory tests (qRT-PCR) are crucial for early diagnosis. We herein report a pediatric patient who presented a coinfection for DENV and COVID-19, \u201cSARS-CoV-2\/Dengue\u201d. This patient initially presented a fever, cough, and headache and, three days later, developed generalized pain and epistaxis. Blood studies revealed thrombocytopenia and leukopenia, and the patient was admitted to the hospital for a probable DENV infection. Within 48 h, qRT-PCR tests specific for SARS-CoV-2 and DENV were performed and resulted as positive. The patient immediately received pharmacological treatment with azithromycin, oseltamivir, and metamizole. During hospitalization (9 days), the patient had no signs of respiratory distress and maintained normal body temperature and normal blood oxygen saturation. This case warns of the need for early diagnosis and adequate clinical and pharmacological management in the face of a \u201cSARS-CoV-2\/Dengue\u201d coinfection. Early molecular detection of both viruses and timely treatment helped the patient to achieve a favorable recovery.<\/jats:p>","DOI":"10.3390\/pathogens11111360","type":"journal-article","created":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T02:24:53Z","timestamp":1668565493000},"page":"1360","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["SARS-CoV-2 and Dengue Virus Coinfection in a Mexican Pediatric Patient: A Case Report from Early Molecular Diagnosis"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6928-0712","authenticated-orcid":false,"given":"Eloy A.","family":"Zepeda-Carrillo","sequence":"first","affiliation":[{"name":"Specialized Unit in Research, Development and Innovation in Genomic Medicine, Nayarit Center for Innovation and Technology Transfer, Autonomous University of Nayarit, Tepic 63000, Mexico"},{"name":"Tepic Specialty Hospital \u201cDr. Antonio Gonz\u00e1lez Guevara\u201d, Health Services in Nayarit, Tepic 63000, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco M.","family":"Soria Saavedra","sequence":"additional","affiliation":[{"name":"Tepic Specialty Hospital \u201cDr. Antonio Gonz\u00e1lez Guevara\u201d, Health Services in Nayarit, Tepic 63000, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria B.","family":"Mercado Villegas","sequence":"additional","affiliation":[{"name":"Tepic Specialty Hospital \u201cDr. Antonio Gonz\u00e1lez Guevara\u201d, Health Services in Nayarit, Tepic 63000, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"L\u00f3pez Alvarado","sequence":"additional","affiliation":[{"name":"State Public Health Laboratory, Health Services in Nayarit, Tepic 63000, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Angel","family":"Regla-Nava","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Pathology, University Center for Health Science (CUCS), University of Guadalajara, Guadalajara 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7089-4343","authenticated-orcid":false,"given":"Rafael","family":"Torres-Valadez","sequence":"additional","affiliation":[{"name":"Specialized Unit in Research, Development and Innovation in Genomic Medicine, Nayarit Center for Innovation and Technology Transfer, Autonomous University of Nayarit, Tepic 63000, Mexico"},{"name":"Integral Health Academic Unit, Autonomous University of Nayarit, Tepic 63000, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e88","DOI":"10.1016\/S1473-3099(16)30473-X","article-title":"Dengue: Knowledge Gaps, Unmet Needs, and Research Priorities","volume":"17","author":"Katzelnick","year":"2017","journal-title":"Lancet Infect. 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