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Here, we report a case of an HIV-negative patient presenting disseminated sporotrichosis with widespread cutaneous lesions mimicking pyoderma gangrenosum, with bone marrow infection, pancytopenia, and hemophagocytic syndrome. However, all the clinical manifestations and a bacterial coinfection delayed the request for a fungal diagnosis. Therefore, sporotrichosis should always be investigated in patients from endemic areas presenting with widespread cutaneous lesions associated with pancytopenia.<\/jats:p>","DOI":"10.3390\/pathogens11121516","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T01:42:27Z","timestamp":1670809347000},"page":"1516","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Late Diagnosis of Disseminated Sporothrix brasiliensis Infection with Bone Marrow Involvement in an HIV-Negative Patient"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0035-6261","authenticated-orcid":false,"given":"Vanessa Caroline Randi","family":"Magalh\u00e3es","sequence":"first","affiliation":[{"name":"Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Av. Ant\u00f4nio Carlos, 6627, Belo Horizonte 31270-901, Brazil"},{"name":"Hospital Eduardo de Menezes, Funda\u00e7\u00e3o Hospitalar do Estado de Minas Gerais (FHEMIG), R. Dr. Cristiano Rezende, 2213, Belo Horizonte 30622-020, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2378-8649","authenticated-orcid":false,"given":"Salene Angelini","family":"Colombo","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine, School of Veterinary, Universidade Federal de Minas Gerais, Av. Ant\u00f4nio Carlos, 6627, Belo Horizonte 31270-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Jos\u00e9 Cota","family":"Freitas","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Av. Ant\u00f4nio Carlos, 6627, Belo Horizonte 31270-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4818-5425","authenticated-orcid":false,"given":"Alexandre Sampaio","family":"Moura","sequence":"additional","affiliation":[{"name":"Hospital Eduardo de Menezes, Funda\u00e7\u00e3o Hospitalar do Estado de Minas Gerais (FHEMIG), R. Dr. Cristiano Rezende, 2213, Belo Horizonte 30622-020, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1via Cardoso Lopez","family":"Vieira","sequence":"additional","affiliation":[{"name":"Hospital Eduardo de Menezes, Funda\u00e7\u00e3o Hospitalar do Estado de Minas Gerais (FHEMIG), R. 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Ant\u00f4nio Carlos, 6627, Belo Horizonte 31270-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Gremi\u00e3o, I.D.F., Miranda, L.H.M., Reis, E.G., Rodrigues, A.M., and Pereira, S.A. (2017). Zoonotic Epidemic of Sporotrichosis: Cat to Human Transmission. PLoS Pathog, 13.","DOI":"10.1371\/journal.ppat.1006077"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Bonifaz, A., and Tirado-S\u00e1nchez, A. (2017). Cutaneous Disseminated and Extracutaneous Sporotrichosis: Current Status of a Complex Disease. J. Fungi, 3.","DOI":"10.3390\/jof3010006"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Rossow, J.A., Queiroz-Telles, F., Caceres, D.H., Beer, K.D., Jackson, B.R., Pereira, J.G., Ferreira Gremi\u00e3o, I.D., and Pereira, S.A. (2020). 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