{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T06:05:57Z","timestamp":1769839557607,"version":"3.49.0"},"reference-count":17,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T00:00:00Z","timestamp":1672358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>The burrowing mite Sarcoptes scabiei causes sarcoptic mange in dogs and other mammals, including humans. Despite S. scabiei infests several animals, little is known about the epidemiology, clinical features, and treatment of sarcoptic mange in cats. A few reports have shown that clinical signs of S. scabiei infestation in cats may vary from non-pruritic crusted lesions to itchy and mild lesions, while severe signs are very infrequent. The present report describes a severe case of S. scabiei infestation in a stray cat from Italy, characterized by bilateral alopecia, diffuse and multifocal hyperpigmented, crusted, erythematous, scaled, and exfoliated lesions. The cat was FIV-positive and also infected by the cestode Dipylidium caninum. After treatment with a broad-spectrum parasiticide and an antibiotic, the cat showed an almost complete clinical recovery in 4 weeks. Unfortunately, no further clinical examinations were performed due to the lack of compliance of the owner and to the death of the cat for causes unrelated to sarcoptic mange. This clinical case indicates that under certain circumstances, S. scabiei can reproduce and cause severe clinical signs in cats which are usually considered non-permissive hosts for this mite, and in which the disease is usually self-limiting. Clinic\u2013pathological, epidemiological, and zoonotic implications are discussed.<\/jats:p>","DOI":"10.3390\/pathogens12010062","type":"journal-article","created":{"date-parts":[[2023,1,2]],"date-time":"2023-01-02T03:50:32Z","timestamp":1672631432000},"page":"62","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["An Uncommon and Severe Clinical Case of Sarcoptes scabiei Infestation in a Cat"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5177-3386","authenticated-orcid":false,"given":"Mariasole","family":"Colombo","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6344-0239","authenticated-orcid":false,"given":"Simone","family":"Morelli","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marzia","family":"Sacra","sequence":"additional","affiliation":[{"name":"Clinica Veterinaria Borghesiana, 00132 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaia","family":"Trezza","sequence":"additional","affiliation":[{"name":"Clinica Veterinaria Borghesiana, 00132 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4247-4867","authenticated-orcid":false,"given":"Barbara","family":"Paoletti","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donato","family":"Traversa","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Di Cesare","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1017\/S0031182016001505","article-title":"A syn- thetic review of Notoedres species mites and mange","volume":"143","author":"Foley","year":"2016","journal-title":"Parasitology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"221-e56","DOI":"10.1111\/vde.12340","article-title":"Evidence-based veterinary dermatology: A review of published studies of treatments for Otodectes cynotis (ear mite) infestation in cats","volume":"27","author":"Yang","year":"2016","journal-title":"Vet. Dermatol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/vde.12806","article-title":"Diagnosis and treatment of demodicosis in dogs and cats: Clinical consensus guidelines of the World Association for Veterinary Dermatology","volume":"31","author":"Mueller","year":"2020","journal-title":"Vet. Dermatol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1136\/vr.101001","article-title":"Feline sarcoptic mange in the UK: A case report","volume":"171","author":"Hardy","year":"2012","journal-title":"Vet. Rec."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e00266-20","DOI":"10.1128\/CMR.00266-20","article-title":"Canine and feline parasitology: Analogies, differences, and relevance for human health","volume":"34","author":"Morelli","year":"2021","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_6","first-page":"85","article-title":"The origin and evolution of host associations of Sarcoptes scabiei and the subfamily Sarcoptinae Murray","volume":"24","author":"Andrews","year":"1983","journal-title":"Acarologia"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.jfms.2006.05.005","article-title":"Crusted scabies (sarcoptic mange) in four cats due to Sarcoptes scabiei infestation","volume":"8","author":"Malik","year":"2006","journal-title":"J. Feline Med. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.vetpar.2008.05.019","article-title":"Long-term study of Sarcoptes scabiei infection in Norwegian red foxes (Vulpes vulpes) indicating host\/parasite adaptation","volume":"156","author":"Davidson","year":"2008","journal-title":"Vet. Parasitol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1111\/jdv.14351","article-title":"European guideline for the management of scabies","volume":"31","author":"Salavastru","year":"2017","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1186\/s13071-017-2234-1","article-title":"A review of Sarcoptes scabiei: Past, present and future","volume":"10","author":"Arlian","year":"2017","journal-title":"Parasites Vectors"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"457-e105","DOI":"10.1111\/vde.12049","article-title":"Feline sarcoptic mange in Taiwan: A case series of five cats","volume":"24","author":"Huang","year":"2013","journal-title":"Vet. Dermatol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s00580-014-2023-6","article-title":"Cat affected with sarcoptic mange in YSR District of Andhra Pradesh, India","volume":"24","author":"Sivajothi","year":"2015","journal-title":"Comp. Clin. Path."},{"key":"ref_13","first-page":"18","article-title":"Two rare disorders in the cat: Demodectic otitis externa and sarcoptic mange","volume":"26","author":"Kontos","year":"1998","journal-title":"Feline Pract."},{"key":"ref_14","first-page":"1572","article-title":"Sarcoptic scabiei infestation in cats","volume":"190","author":"Hawkins","year":"1987","journal-title":"J. Am. Vet. Med. Ass."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1097\/00007611-199403000-00011","article-title":"Crusted (Norwegian) scabies in patients with AIDS: The range of clinical presentations","volume":"87","author":"Schlesinger","year":"1994","journal-title":"South. Med. J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1186\/s13071-017-2320-4","article-title":"Host immune responses to the itch mite, Sarcoptes scabiei, in humans","volume":"10","author":"Bhat","year":"2017","journal-title":"Parasites Vectors"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.3201\/eid2506.181891","article-title":"Sarcoptic mange of fox origin in multiple farm animals and scabies in humans, Switzerland, 2018","volume":"25","author":"Pisano","year":"2019","journal-title":"Emerg. Infect. 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