{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:38:37Z","timestamp":1790127517131,"version":"4.0.1"},"reference-count":66,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Scientific Grant Agency of Ministry of Education, Science, Research and Sport of the Slovak Republic and Slovak Academy of Sciences","award":["VEGA 2\/0108\/22"],"award-info":[{"award-number":["VEGA 2\/0108\/22"]}]},{"name":"Scientific Grant Agency of Ministry of Education, Science, Research and Sport of the Slovak Republic and Slovak Academy of Sciences","award":["APVV 21-0431"],"award-info":[{"award-number":["APVV 21-0431"]}]},{"name":"Slovak Research and Development Agency","award":["VEGA 2\/0108\/22"],"award-info":[{"award-number":["VEGA 2\/0108\/22"]}]},{"name":"Slovak Research and Development Agency","award":["APVV 21-0431"],"award-info":[{"award-number":["APVV 21-0431"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>There is increasing evidence that arthropod-borne pathogens exploit saliva of their vectors during the transmission process to vertebrate hosts. Extensive research of the composition of tick saliva and its role in blood-feeding and transmission of pathogens started in the late 1980s and led to a number of discoveries on the composition and function of salivary molecules, some of which are associated with pathogen transmission. The study by Jones et al. published in 1989 can be ranked among the pioneer works in this field as it demonstrated for the first time the role of tick salivary glands in enhancement of transmission of a tick-borne virus. Thogoto virus was used in the model and subsequently similar results were obtained for tick-borne encephalitis virus. After a relatively silent period of almost 20 years, interest in tick\u2013arbovirus\u2013host interactions emerged again in the 2010s. However, no particular salivary molecule(s) enhancing virus transmission has (have) been identified to date. Intensive research in this field will certainly lead to new discoveries with future implications in the control of transmission of dangerous tick-borne viruses.<\/jats:p>","DOI":"10.3390\/pathogens12020334","type":"journal-article","created":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T02:04:03Z","timestamp":1676513043000},"page":"334","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Discovery of the Role of Tick Salivary Glands in Enhancement of Virus Transmission\u2014Beginning of an Exciting Story"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3979-2001","authenticated-orcid":false,"given":"Pavl\u00edna","family":"Bart\u00edkov\u00e1","sequence":"first","affiliation":[{"name":"Institute of Virology, Biomedical Research Center, Slovak Academy of Sciences, D\u00fabravsk\u00e1 Cesta 9, 845 05 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iveta","family":"\u0160tibr\u00e1niov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Virology, Biomedical Research Center, Slovak Academy of Sciences, D\u00fabravsk\u00e1 Cesta 9, 845 05 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6904-8342","authenticated-orcid":false,"given":"M\u00e1ria","family":"Kazim\u00edrov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Zoology, Slovak Academy of Sciences, D\u00fabravsk\u00e1 Cesta 9, 845 06 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"ref_1","unstructured":"Obenchain, F.D., and Galun, R. 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