{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:52:12Z","timestamp":1790711532208,"version":"4.1.0"},"reference-count":40,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,6,5]],"date-time":"2023-06-05T00:00:00Z","timestamp":1685923200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"ALF (Region Sk\u00e5ne\/Lund University)"},{"name":"SUS fonder"},{"name":"S\u00f6dra Sjukv\u00e5rdsregionen"},{"name":"Crafoordska Stiftelsen"},{"name":"Alfred \u00d6sterlunds Stiftelse"},{"name":"Stiftelsen Sigurd och Elsa Goljes Minne"},{"name":"O. E. och Edla Johanssons Stiftelse"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Babesia is spread to humans via ticks or blood transfusions. Severity of Plasmodium falciparum malaria is strongly correlated to the ABO blood group of the patient. Babesia divergens is an intraerythrocytic parasite with many similarities to malaria, but the impact of ABO on the susceptibility to and progression of the infection in humans is unknown. We have now cultured B. divergens in human group A, B and O erythrocytes in vitro and measured rates of multiplication. The predilection for the different erythrocyte types was also determined using an in vitro erythrocyte preference assay when the parasites were grown in group A, B or O erythrocytes over time and then offered to invade differently stained erythrocytes of all the blood types at the same time. The results showed no difference in multiplication rates for the different blood types, and the parasite exhibited no obvious morphological differences in the different blood types. When cultured first in one blood type and then offered to grow in the others, the preference assay showed that there was no difference between the A, B or O blood groups. In conclusion, this indicates that individuals of the different ABO blood types are likely to be equally susceptible to B. divergens infections.<\/jats:p>","DOI":"10.3390\/pathogens12060803","type":"journal-article","created":{"date-parts":[[2023,6,5]],"date-time":"2023-06-05T04:01:47Z","timestamp":1685937707000},"page":"803","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Babesia divergens Shows Equal Predilection for Human ABO Blood Types in an In Vitro Erythrocyte Preference Assay"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3182-8949","authenticated-orcid":false,"given":"Muyideen K.","family":"Tijani","sequence":"first","affiliation":[{"name":"Cellular Parasitology Programme, Cell Biology and Genetics Unit, Department of Zoology, University of Ibadan, Ibadan 200132, Nigeria"},{"name":"Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, 22185 Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Danielsson","sequence":"additional","affiliation":[{"name":"Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, 22185 Lund, Sweden"},{"name":"Clinical Chemistry and Pharmacology, Laboratory Medicine, Office for Medical Services, Region Sk\u00e5ne, 22185 Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill R.","family":"Storry","sequence":"additional","affiliation":[{"name":"Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, 22185 Lund, Sweden"},{"name":"Department of Clinical Immunology and Transfusion Medicine, Office for Medical Services, Region Sk\u00e5ne, 22185 Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1647-9610","authenticated-orcid":false,"given":"Martin L.","family":"Olsson","sequence":"additional","affiliation":[{"name":"Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, 22185 Lund, Sweden"},{"name":"Department of Clinical Immunology and Transfusion Medicine, Office for Medical Services, Region Sk\u00e5ne, 22185 Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2661-3115","authenticated-orcid":false,"given":"Kristina E. M.","family":"Persson","sequence":"additional","affiliation":[{"name":"Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, 22185 Lund, Sweden"},{"name":"Clinical Chemistry and Pharmacology, Laboratory Medicine, Office for Medical Services, Region Sk\u00e5ne, 22185 Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/MOH.0000000000000606","article-title":"Human babesiosis: Recent advances and future challenges","volume":"27","author":"Lobo","year":"2020","journal-title":"Curr. Opin. Hematol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1093\/cid\/cix216","article-title":"Possible Transfusion-Transmitted Babesia divergens-like\/MO-1 Infection in an Arkansas Patient","volume":"64","author":"Burgess","year":"2017","journal-title":"Clin. 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