{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T11:03:37Z","timestamp":1761649417549,"version":"build-2065373602"},"reference-count":8,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T00:00:00Z","timestamp":1730073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>During the COVID-19 pandemic, prenatal care services were disrupted. We analyzed the trajectory slopes of cases of congenital toxoplasmosis (CT) and acute toxoplasmosis during pregnancy from 2019 to 2022 (to reflect the cases during the pandemic years 2020\u20132022) vs. 2000 to 2019, using data from the Remington Laboratory, the National Reference Center for Toxoplasmosis in the US. During the pandemic, there was a statistically significant upward trajectory in the yearly number of CT cases. Monitoring of this trend is needed.<\/jats:p>","DOI":"10.3390\/pathogens13110937","type":"journal-article","created":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T11:52:47Z","timestamp":1730116367000},"page":"937","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Increase in Congenital Toxoplasmosis During the COVID-19 Pandemic in the US"],"prefix":"10.3390","volume":"13","author":[{"given":"Despina G.","family":"Contopoulos-Ioannidis","sequence":"first","affiliation":[{"name":"Dr. Jack S. Remington Laboratory for Specialty Diagnostics, Palo Alto Medical Foundation, Sutter Health, Palo Alto, CA 94301, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Bonetti","sequence":"additional","affiliation":[{"name":"Dr. Jack S. Remington Laboratory for Specialty Diagnostics, Palo Alto Medical Foundation, Sutter Health, Palo Alto, CA 94301, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose G.","family":"Montoya","sequence":"additional","affiliation":[{"name":"Dr. Jack S. Remington Laboratory for Specialty Diagnostics, Palo Alto Medical Foundation, Sutter Health, Palo Alto, CA 94301, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.3201\/eid2707.204670","article-title":"Prolonged SARS-CoV-2 RNA Shedding from Therapy Cat after Cluster Outbreak in Retirement Home","volume":"27","author":"Schulz","year":"2021","journal-title":"Emerg. Infect. Dis."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Doliff, R., and Martens, P. (2022). Cats and SARS-CoV-2: A Scoping Review. Animals, 12.","DOI":"10.3390\/ani12111413"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"de Oliveira-Filho, E.F., de Carvalho, O.V., Carneiro, I.O., Fernandes, F., Vaz, S.N., Pedroso, C., Gonzalez-Auza, L., Urbieta, V.C., K\u00fchne, A., and Mayoral, R. (2022). Frequent Infection of Cats with SARS-CoV-2 Irrespective of Pre-Existing Enzootic Coronavirus Immunity, Brazil 2020. Front. Immunol., 13.","DOI":"10.3389\/fimmu.2022.857322"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1056\/NEJMc2013400","article-title":"Transmission of SARS-CoV-2 in Domestic Cats","volume":"383","author":"Halfmann","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Hebert, M., Bouhout, S., Vadboncoeur, J., and Aubin, M.J. (2022). Recurrent and De Novo Toxoplasmosis Retinochoroiditis following Coronavirus Disease 2019 Infection or Vaccination. Vaccines, 10.","DOI":"10.3390\/vaccines10101692"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s10238-021-00751-7","article-title":"COVID-19-associated opportunistic infections: A snapshot on the current reports","volume":"22","author":"Abdoli","year":"2022","journal-title":"Clin. Exp. Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1093\/trstmh\/trab142","article-title":"Considering opportunistic parasitic infections in COVID-19 policies and recommendations","volume":"115","author":"Mewara","year":"2021","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s13256-023-03855-8","article-title":"First description of congenital toxoplasmosis after maternal coinfection with Toxoplasma gondii and severe acute respiratory syndrome coronavirus 2: A case report","volume":"17","author":"Dao","year":"2023","journal-title":"J. Med. Case Rep."}],"container-title":["Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-0817\/13\/11\/937\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:22:25Z","timestamp":1760113345000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-0817\/13\/11\/937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,28]]},"references-count":8,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11]]}},"alternative-id":["pathogens13110937"],"URL":"https:\/\/doi.org\/10.3390\/pathogens13110937","relation":{},"ISSN":["2076-0817"],"issn-type":[{"type":"electronic","value":"2076-0817"}],"subject":[],"published":{"date-parts":[[2024,10,28]]}}}