{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T07:26:41Z","timestamp":1781249201400,"version":"3.54.1"},"reference-count":49,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Organisation de Coordination pour la lutte contre les End\u00e9mies en Afrique Centrale (OCEAC)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>This prospective survey determined the prevalence and intensity of infections due to geohelminths and the associated risk factors in five onchocerciasis-endemic communities in Gabon between January and February 2020. Onchocerciasis endemicity was confirmed by Ov16 IgG testing. STHs were detected using the Kato\u2013Katz techniques. Prevalence and parasite density were analyzed according to age, sex, and onchocerciasis endemicity. STHs were found in 64.8% of participants and were more common in hypoendemic (80.9%) and hyperendemic (63.9%) onchocerciasis communities (p &lt; 0.01). Ascaris lumbricoides (65.5%), Trichuris trichiura (57.1%), and hookworms (17.3%) were prevalent in areas hypoendemic for onchocerciasis (p = 0.04). Male participants were more often infected by hookworms. Adults were more frequently infected by STHs (75.9%) than elders, who were the least infected (39.3%) (p &lt; 0.01). Participants living in sporadic onchocerciasis areas frequently but not significantly harbored a moderate ascariasis load (6960.0 (1068.0\u20139492.0) eggs per gram) (p = 0.4). The highest parasite density was observed among participants aged 20\u201345 years (15,336.0 (3888.0\u201335,028.0)). A low T. trichiuria prevalence was found in all communities. STHs are highly prevalent in hypoendemic and hyperendemic areas and adults. An integrated combined approach of STH and onchocerciasis elimination through efficacious mass drug administration targeting all age groups should be considered.<\/jats:p>","DOI":"10.3390\/pathogens13110967","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T06:27:39Z","timestamp":1730874459000},"page":"967","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prevalence and Sociodemographic Risk Factors of Soil-Transmitted Helminths in Rural Communities Living in Endemic Foci of Onchocerciasis in Southern Gabon"],"prefix":"10.3390","volume":"13","author":[{"given":"Reinne","family":"Moutongo Mouandza","sequence":"first","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Recherche en Pathog\u00e8nes Infectieux et Pathologies Associ\u00e9es (CREIPA), Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Formation et de Recherche en Microbiologie-Maladies Infectieuses et Tropicales (CREMMIT), Institute of Infectious Diseases Pr. Daniel Gahouma, Owendo P.O. Box 18141, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Romain","family":"Mourou Mbina","sequence":"additional","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7811-2334","authenticated-orcid":false,"given":"Bridy","family":"Moutombi Ditombi","sequence":"additional","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Recherche en Pathog\u00e8nes Infectieux et Pathologies Associ\u00e9es (CREIPA), Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Formation et de Recherche en Microbiologie-Maladies Infectieuses et Tropicales (CREMMIT), Institute of Infectious Diseases Pr. Daniel Gahouma, Owendo P.O. Box 18141, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce Coella","family":"Mihindou","sequence":"additional","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Recherche en Pathog\u00e8nes Infectieux et Pathologies Associ\u00e9es (CREIPA), Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Formation et de Recherche en Microbiologie-Maladies Infectieuses et Tropicales (CREMMIT), Institute of Infectious Diseases Pr. Daniel Gahouma, Owendo P.O. Box 18141, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitri Ardrin","family":"Moussavou Mabicka","sequence":"additional","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Recherche en Pathog\u00e8nes Infectieux et Pathologies Associ\u00e9es (CREIPA), Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Formation et de Recherche en Microbiologie-Maladies Infectieuses et Tropicales (CREMMIT), Institute of Infectious Diseases Pr. Daniel Gahouma, Owendo P.O. Box 18141, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Mayandza","sequence":"additional","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Recherche en Pathog\u00e8nes Infectieux et Pathologies Associ\u00e9es (CREIPA), Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noe Patrick","family":"Mbondoukwe","sequence":"additional","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Recherche en Pathog\u00e8nes Infectieux et Pathologies Associ\u00e9es (CREIPA), Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Formation et de Recherche en Microbiologie-Maladies Infectieuses et Tropicales (CREMMIT), Institute of Infectious Diseases Pr. Daniel Gahouma, Owendo P.O. Box 18141, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bedrich","family":"Pongui Ngondza","sequence":"additional","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Recherche en Pathog\u00e8nes Infectieux et Pathologies Associ\u00e9es (CREIPA), Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luccheri","family":"Ndong Akomezoghe","sequence":"additional","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"},{"name":"Centre de Recherche en Pathog\u00e8nes Infectieux et Pathologies Associ\u00e9es (CREIPA), Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. Box 4009, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise Patricia","family":"Mawili Mboumba","sequence":"additional","affiliation":[{"name":"Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Universit\u00e9 des Sciences de la Sant\u00e9, Libreville P.O. 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Box 4009, Gabon"},{"name":"Centre de Formation et de Recherche en Microbiologie-Maladies Infectieuses et Tropicales (CREMMIT), Institute of Infectious Diseases Pr. Daniel Gahouma, Owendo P.O. Box 18141, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"World Health Organization (2024, July 24). Global Report on NTD 2024, Available online: https:\/\/www.who.int\/teams\/control-of-neglected-tropical-diseases\/global-report-on-neglected-tropical-diseases-2024.","DOI":"10.1016\/S1473-3099(24)00365-7"},{"key":"ref_2","unstructured":"World Health Organization (2012). Soil-Transmitted Helminthiases: Eliminating as Public Health Problem Soil-Transmitted Helminthiases in Children: Progress Report 2001\u20132010 and Strategic Plan 2011\u20132020."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"j4307","DOI":"10.1136\/bmj.j4307","article-title":"Efficacy of recommended drugs against soil transmitted helminths: Systematic review and network meta-analysis","volume":"358","author":"Moser","year":"2017","journal-title":"BMJ"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40249-021-00802-x","article-title":"Polyparasitism with Schistosoma haematobium, Plasmodium and soil-transmitted helminths in school-aged children in Muyuka-Cameroon following implementation of control measures: A cross sectional study","volume":"10","author":"Sumbele","year":"2021","journal-title":"Infect. Dis. Poverty"},{"key":"ref_5","unstructured":"World Health Organization (2015). Rapport de mission de cartographie de l\u2019onchocercose et de la loase dans 69 village au Gabon, African Programme for Onchocerciasis Control (APOC)."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s40249-017-0381-4","article-title":"Prevalence of and risk factors for malaria, filariasis, and intestinal parasites as single infections or co-infections in different settlements of Gabon, Central Africa","volume":"7","author":"Kendjo","year":"2018","journal-title":"Infect. Dis. Poverty"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"325","DOI":"10.4269\/ajtmh.19-0835","article-title":"Epidemiology of Schistosomiasis and Soil-Transmitted Helminth Coinfections among Schoolchildren Living in Lambarene, Gabon","volume":"103","author":"Honkpehedji","year":"2020","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1186\/1756-3305-7-325","article-title":"The geographic distribution of onchocerciasis in the 20 participating countries of the African Programme for Onchocerciasis Control: (2) pre-control endemicity levels and estimated number infected","volume":"7","author":"Noma","year":"2014","journal-title":"Parasites Vectors"},{"key":"ref_9","unstructured":"World Health Organization (2022). Expanded special Project for Elimination of NTD, Gabon 2020: Status of Onchocerciasis Elimination."},{"key":"ref_10","unstructured":"World Health Organization (2020). Ending the Neglect to Attain the Sustainable Development Goals: A Road Map for Neglected Tropical Diseases 2021\u20132030."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0065-308X(10)73002-5","article-title":"Multiparasitism a neglected reality on global, regional and local scale","volume":"73","author":"Steinmann","year":"2010","journal-title":"Adv. Parasitol."},{"key":"ref_12","first-page":"53","article-title":"The Mectizan donation program in Gabon: Progress and perspectives of distribution in the focus of onchocerciasis (1991\u20131997)","volume":"8","author":"Kombila","year":"1998","journal-title":"Sante"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1056\/NEJMoa1705026","article-title":"A Test-and-Not-Treat Strategy for Onchocerciasis in Loa loa\u2013Endemic Areas","volume":"377","author":"Kamgno","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e1047","DOI":"10.1093\/cid\/ciaa1829","article-title":"Feasibility of Onchocerciasis Elimination Using a \u201cTest-and-not-treat\u201d Strategy in Loa loa Co-endemic Areas","volume":"72","author":"Blok","year":"2021","journal-title":"Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s40249-019-0553-5","article-title":"Soil-transmitted helminth infection in school age children in Sierra Leone after a decade of preventive chemotherapy interventions","volume":"8","author":"Bah","year":"2019","journal-title":"Infect. Dis. Poverty"},{"key":"ref_16","first-page":"74","article-title":"Soil-transmitted Helminth infection in the Tiko Health District, South West Region of Cameroon: A post-intervention survey on prevalence and intensity of infection among primary school children","volume":"30","author":"Tabi","year":"2018","journal-title":"Pan Afr. Med. J."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Palmeirim, M.S., H\u00fcrlimann, E., Knopp, S., Speich, B., Belizario, V., Joseph, S.A., Vaillant, M., Olliaro, P., and Keiser, J. (2018). Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths: A systematic review, meta-analysis and individual patient data analysis. PLoS Neglected Trop. Dis., 12.","DOI":"10.1371\/journal.pntd.0006458"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Gebrezgabiher, G., Yewhalaw, D., Ayana, M., Hailu, A., and Mekonnen, Z. (2022). Impact of ivermectin mass drug administration on burden of soil-transmitted helminths in onchocerciasis control and elimination programs, Yeki district, southwest Ethiopia. PLoS ONE, 17.","DOI":"10.1371\/journal.pone.0263625"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"de Vos, A.S., Stolk, W.A., Coffeng, L.E., and de Vlas, S.J. (2021). The impact of mass drug administration expansion to low onchocerciasis prevalence settings in case of connected villages. PLoS Neglected Trop. Dis., 15.","DOI":"10.1371\/journal.pntd.0009011"},{"key":"ref_20","unstructured":"Metcalfe, C. (1999). Biostatistics: A Foundation for Analysis in the Health Sciences, Wiley. [7th ed.]."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9734\/IJTDH\/2016\/26774","article-title":"Prevalence of Soil-transmitted Helminths and Intestinal Protozoa in Shanty Towns of Libreville, Gabon","volume":"20","author":"Mbondoukwe","year":"2016","journal-title":"Int. J. Trop. Dis. Health"},{"key":"ref_22","first-page":"35","article-title":"Comparative examinations","volume":"3","author":"Kato","year":"1954","journal-title":"Jpn. J. Parasitol."},{"key":"ref_23","first-page":"177","article-title":"A New Method for culturing Hook Worm","volume":"1","author":"Harada","year":"1955","journal-title":"Yonago Acta Med."},{"key":"ref_24","unstructured":"Ash, L.R., Orihe, T.C., and LSavioli, L. (2019). Bench Aids for the Diagnosis of Intestinal Parasites, WHO. [2nd ed.]."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.pt.2015.06.007","article-title":"Diagnostic Tools for Onchocerciasis Elimination Programs","volume":"31","author":"Vlaminck","year":"2015","journal-title":"Trends Parasitol."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Hotterbeekx, A., Perneel, J., Mandro, M., Abhafule, G., Siewe Fodjo, J.N., Dusabimana, A., Abrams, S., Kumar-Singh, S., and Colebunders, R. (2020). Comparison of Diagnostic Tests for Onchocerca volvulus in the Democratic Republic of Congo. Pathogens, 9.","DOI":"10.3390\/pathogens9060435"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s40249-020-0630-9","article-title":"Neglected tropical diseases: An effective global response to local poverty-related disease priorities","volume":"9","author":"Engels","year":"2020","journal-title":"Infect Dis. Poverty"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.ijpara.2009.10.016","article-title":"Epidemiology and control of onchocerciasis: The threshold biting rate of savannah onchocerciasis in Africa","volume":"40","author":"Duerr","year":"2010","journal-title":"Int. J. Parasitol."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Eyang-Assengone, E.R., Makouloutou-Nzassi, P., Mbou-Boutambe, C., Bangueboussa, F., Atsame, J., and Boundenga, L. (2023). Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review. Microorganisms, 11.","DOI":"10.3390\/microorganisms11081946"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Mintsa Nguema, R., Mavoungou, J.F., Mengue Me Ngou-Milama, K., Mabicka Mamfoumbi, M., Koumba, A.A., Sani Lamine, M., Diarra, A., Nkone Asseko, G., Mourou, J.R., and Bouyou Akotet, M.K. (2018). Baseline Mapping of Schistosomiasis and Soil Transmitted Helminthiasis in the Northern and Eastern Health Regions of Gabon, Central Africa: Recommendations for Preventive Chemotherapy. Trop. Med. Infect. Dis., 3.","DOI":"10.20944\/preprints201808.0442.v1"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"844","DOI":"10.4269\/ajtmh.22-0392","article-title":"Integrated Prevalence Assessment of Wuchereria bancrofti and Onchocerca volvulus in Three Co-Endemic Districts of Gambella Region, Ethiopia","volume":"109","author":"Hassen","year":"2023","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"850","DOI":"10.4269\/ajtmh.22-0558","article-title":"Sociodemographics, Clinical Factors, and Biological Factors Associated with Loiasis in Endemic Onchocerciasis Areas in Southern Gabon","volume":"109","author":"Mourou","year":"2023","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Tekalign, E., Bajiro, M., Ayana, M., Tiruneh, A., and Belay, T. (2019). Prevalence and Intensity of Soil-Transmitted Helminth Infection among Rural Community of Southwest Ethiopia: A Community-Based Study. Biomed. Res. Int., 2019.","DOI":"10.1155\/2019\/3687873"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Dieye, Y., Storey, H.L., Barrett, K.L., Gerth-Guyette, E., Di Giorgio, L., Golden, A., Faulx, D., Kalnoky, M., Ndiaye, M.K.N., and Sy, N. (2017). Feasibility of utilizing the SD BIOLINE Onchocerciasis IgG4 rapid test in onchocerciasis surveillance in Senegal. PLoS Neglected Trop. Dis., 11.","DOI":"10.1371\/journal.pntd.0005884"},{"key":"ref_35","unstructured":"WHO (2016). Guidelines for Stopping Mass Drug Administration and Verifying Elimination of Human Onchocerciasis: Criteria and Procedures, WHO\/HTM\/NTD\/PCT\/2016.1."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Yang, D., Yang, Y., Wang, Y., Yang, Y., Dong, S., Chen, Y., and Zho, Y.U. (2018). Prevalence and Risk Factors of Ascaris lumbricoides, Trichuris trichiura and Cryptosporidium Infections in Elementary School Children in Southwestern China: A School-Based Cross-Sectional Study. Int. J. Environ. Res. Public Health, 15.","DOI":"10.3390\/ijerph15091809"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1016\/S0140-6736(15)61022-4","article-title":"Onchocerciasis and lymphatic filariasis elimination in Africa: It\u2019s about time","volume":"385","author":"Evans","year":"2015","journal-title":"Lancet"},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Dolo, H., Coulibaly, Y.I., Dembele, B., Guindo, B., Coulibaly, S.Y., Dicko, I., Doumbia, S.S., Dembele, M., Traore, M.O., and Goita, S. (2019). Integrated seroprevalence-based assessment of Wuchereria bancrofti and Onchocerca volvulus in two lymphatic filariasis evaluation units of Mali with the SD Bioline Onchocerciasis\/LF IgG4 Rapid Test. PLoS Neglected Trop. Dis., 13.","DOI":"10.1371\/journal.pntd.0007064"},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Asfaw, M.A., Gezmu, T., Wegayehu, T., Bekele, A., Hailemariam, Z., Masresha, N., and Gebre, T. (2020). Soil-transmitted helminth infections among pre-school aged children in Gamo Gofa zone, Southern Ethiopia: Prevalence, intensity and intervention status. PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0243946"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1365-3156.2005.01541.x","article-title":"Synergistic associations between hookworm and other helminth species in a rural community in Brazil","volume":"11","author":"Fleming","year":"2006","journal-title":"Trop. Med. Int. Health"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Blackwell, A.D., Martin, M., Kaplan, H., and Gurven, M. (2013). Antagonism between two intestinal parasites in humans: The importance of co-infection for infection risk and recovery dynamics. Proc. Biol. Sci., 280.","DOI":"10.1098\/rspb.2013.1671"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s13071-016-1310-2","article-title":"Epidemiological surveys of, and research on, soil-transmitted helminths in Southeast Asia: A systematic review","volume":"9","author":"Dunn","year":"2016","journal-title":"Parasites Vectors"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1017\/S0021932016000201","article-title":"Potential Contribution of Adult Populations to the Maintenance of Schistosomiasis and Soil-Transmitted Helminth Infections in the Siavonga and Mazabuka Districts of Zambia","volume":"49","author":"Halwindi","year":"2017","journal-title":"J. Biosoc. Sci."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.trstmh.2004.05.006","article-title":"Associations between filarial and gastrointestinal nematodes","volume":"99","author":"Faulkner","year":"2005","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s40249-019-0567-z","article-title":"Reaching the last mile: Main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa","volume":"8","author":"Gebrezgabiher","year":"2019","journal-title":"Infect. Dis. Poverty"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S1473-3099(14)71050-3","article-title":"Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infections: A four-arm, randomised controlled trial","volume":"15","author":"Speich","year":"2015","journal-title":"Lancet Infect. Dis."},{"key":"ref_47","first-page":"100942","article-title":"Effectiveness of one and two doses of ivermectin mass drug administration in reducing the prevalence and intensity of soil-transmitted helminth (STH) infections in Western Province, Solomon Islands: A cluster-randomised, before-after analysis","volume":"42","author":"Le","year":"2024","journal-title":"Lancet Reg. Health West. Pac."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1093\/cid\/ciy423","article-title":"Efficacy of Anthelminthic Drugs and Drug Combinations Against Soil-transmitted Helminths: A Systematic Review and Network Meta-analysis","volume":"68","author":"Clarke","year":"2019","journal-title":"Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am."},{"key":"ref_49","first-page":"35","article-title":"A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp.","volume":"81","author":"Belizario","year":"2003","journal-title":"Bull. World Health Organ."}],"container-title":["Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-0817\/13\/11\/967\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:26:55Z","timestamp":1760113615000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-0817\/13\/11\/967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,6]]},"references-count":49,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11]]}},"alternative-id":["pathogens13110967"],"URL":"https:\/\/doi.org\/10.3390\/pathogens13110967","relation":{},"ISSN":["2076-0817"],"issn-type":[{"value":"2076-0817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,6]]}}}