{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:08:14Z","timestamp":1777673294748,"version":"3.51.4"},"reference-count":74,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FUNDA\u00c7\u00c3O DE AMPARO \u00c0 PESQUISA E INOVA\u00c7\u00c3O DO ESP\u00cdRITO SANTO","award":["51863.796.17733.30092022"],"award-info":[{"award-number":["51863.796.17733.30092022"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>The filtrate of the nematophagous fungus Duddingtonia flagrans produces silver nanoparticles (AgNPs) with nematicidal potential. However, there are currently no reports of its activity against Toxocara canis eggs. The aim of this study was to investigate the potential ovicidal activity of AgNPs\u2013D. flagrans on T. canis eggs. T. canis eggs were obtained from the dissection of the uterus of adult female nematodes. After the biosynthesis of AgNPs, two experimental assays (A and B) were performed. In assay A, the ovicidal activity of AgNPs on eggs was evaluated after 15 and 30 days of interaction. In assay B, the inhibition (development) of the eggs was measured after 30 days of interaction. The results of assay A showed that the AgNPs destroyed an average of 47% of the eggs tested by the end of the experiment, causing significant structural damage. In assay B, an inhibition rate of 88% was observed at the end of 30 days. The results of the ovicidal activity of AgNP\u2013D. flagrans were promising and indicate the potential for future studies on these biomolecules with ovicidal properties.<\/jats:p>","DOI":"10.3390\/pathogens13121043","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T08:17:42Z","timestamp":1732695462000},"page":"1043","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Silver Nanoparticles from Duddingtonia flagrans: Evaluation of Potential Ovicidal Activity on Toxocara canis Eggs"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0390-3240","authenticated-orcid":false,"given":"Carolina Magri","family":"Ferraz","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Parasitologia Experimental e Controle Biol\u00f3gico, Universidade Vila Velha, Rua S\u00e3o Joao, 48, Vila Velha 29101-420, ES, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lara Coslop","family":"Com\u00e9rio","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Parasitologia Experimental e Controle Biol\u00f3gico, Universidade Vila Velha, Rua S\u00e3o Joao, 48, Vila Velha 29101-420, ES, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vin\u00edcius Bastos Salles","family":"Segantine","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Parasitologia Experimental e Controle Biol\u00f3gico, Universidade Vila Velha, Rua S\u00e3o Joao, 48, Vila Velha 29101-420, ES, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Pedro Barbosa","family":"de Assis","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Parasitologia Experimental e Controle Biol\u00f3gico, Universidade Vila Velha, Rua S\u00e3o Joao, 48, Vila Velha 29101-420, ES, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4278-8089","authenticated-orcid":false,"given":"Laryssa Pinheiro","family":"Costa Silva","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Parasitologia Experimental e Controle Biol\u00f3gico, Universidade Vila Velha, Rua S\u00e3o Joao, 48, Vila Velha 29101-420, ES, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lara De Nadai Rodrigues","family":"Bezerra","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Parasitologia Experimental e Controle Biol\u00f3gico, Universidade Vila Velha, Rua S\u00e3o Joao, 48, Vila Velha 29101-420, ES, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7367-4071","authenticated-orcid":false,"given":"Jackson Victor","family":"de Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Veterin\u00e1ria, Universidade Federal de Vi\u00e7osa, Avenida PH Rolfs, Vi\u00e7osa 36570-000, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9891-7842","authenticated-orcid":false,"given":"Vin\u00edcius Longo Ribeiro","family":"Vilela","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Veterin\u00e1ria, Instituto Federal da Para\u00edba\u2014IFPB, Rua Presidente Tancredo Neves, Sousa 58800-970, PB, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippe Elias de Freitas","family":"Soares","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica, Universidade Federal de Lavras, Rua Professor Edmir S\u00e1 Santos, Lavras 37203-202, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7967-7628","authenticated-orcid":false,"given":"Gabriel Augusto Marques","family":"Rossi","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Parasitologia Experimental e Controle Biol\u00f3gico, Universidade Vila Velha, Rua S\u00e3o Joao, 48, Vila Velha 29101-420, ES, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3841-480X","authenticated-orcid":false,"given":"Fernando Luiz","family":"Tobias","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Parasitologia Experimental e Controle Biol\u00f3gico, Universidade Vila Velha, Rua S\u00e3o Joao, 48, Vila Velha 29101-420, ES, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5127-0762","authenticated-orcid":false,"given":"Helio","family":"Langoni","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Parasitologia Experimental e Controle Biol\u00f3gico, Universidade Vila Velha, Rua S\u00e3o Joao, 48, Vila Velha 29101-420, ES, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio 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