{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:41:14Z","timestamp":1787496074779,"version":"build-2736575974"},"reference-count":44,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,12,8]],"date-time":"2024-12-08T00:00:00Z","timestamp":1733616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministerio de Industria y Turismo","award":["IDI-050300-2023-7"],"award-info":[{"award-number":["IDI-050300-2023-7"]}]},{"name":"Ministerio de Industria y Turismo","award":["DIN2020-011251"],"award-info":[{"award-number":["DIN2020-011251"]}]},{"DOI":"10.13039\/501100004837","name":"Industrial Doctoral Program","doi-asserted-by":"publisher","award":["IDI-050300-2023-7"],"award-info":[{"award-number":["IDI-050300-2023-7"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Industrial Doctoral Program","doi-asserted-by":"publisher","award":["DIN2020-011251"],"award-info":[{"award-number":["DIN2020-011251"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European NEXTGENERATION funds","award":["IDI-050300-2023-7"],"award-info":[{"award-number":["IDI-050300-2023-7"]}]},{"name":"European NEXTGENERATION funds","award":["DIN2020-011251"],"award-info":[{"award-number":["DIN2020-011251"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>The Eurasian wild boar (Sus scrofa) is a key wildlife host for tuberculosis (TB) in central and southwestern Spain, posing a challenge to TB eradication in livestock. New strategies, including the use of beneficial microbes, are being explored to mitigate wildlife diseases. This study evaluated the effect of oral supplementation with postbiotic antimycobacterial metabolites produced using Ingulados\u2019 lactic acid bacteria (LAB) collection on TB development in wild boar. A total of 20 game estates in mid-western Spain were divided into two groups: one fed with standard feed containing the postbiotic product and a control group fed without postbiotics. Data were collected from wild boar during hunting events pre- and post-supplementation. The presence of TB-like lesions (TBLLs), lesion severity and seropositivity against Mycobacterium bovis were assessed. Postbiotic supplementation led to a 36.87% reduction in TBLLs and a 35.94% decrease in seropositivity. Notably, young wild boar showed a 64.72% reduction in TBLLs and an 81.80% drop in seropositivity, suggesting reduced transmission. These findings support the potential of postbiotics as a safe, feasible and sustainable tool to control TB in wild boar, offering a promising addition to broader TB eradication efforts.<\/jats:p>","DOI":"10.3390\/pathogens13121078","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T04:01:37Z","timestamp":1733716897000},"page":"1078","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effect of Lactic Acid Bacteria-Derived Postbiotic Supplementation on Tuberculosis in Wild Boar Populations"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2194-3756","authenticated-orcid":false,"given":"Maria","family":"Bravo","sequence":"first","affiliation":[{"name":"Ingulados S.L., Calle Miguel Servet 13, 10003 C\u00e1ceres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Ingulados S.L., Calle Miguel Servet 13, 10003 C\u00e1ceres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waldo","family":"Garc\u00eda-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Ingulados S.L., Calle Miguel Servet 13, 10003 C\u00e1ceres, Spain"},{"name":"Unidad de Histolog\u00eda y Anatom\u00eda Patol\u00f3gica, Departamento de Medicina Animal, Veterinary Faculty, University of C\u00e1ceres, Avenida de la Universidad s\/n, 10003 C\u00e1ceres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Montero","sequence":"additional","affiliation":[{"name":"Ingulados S.L., Calle Miguel Servet 13, 10003 C\u00e1ceres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Cerrato","sequence":"additional","affiliation":[{"name":"Ingulados S.L., Calle Miguel Servet 13, 10003 C\u00e1ceres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Fern\u00e1ndez-Llario","sequence":"additional","affiliation":[{"name":"Ingulados S.L., Calle Miguel Servet 13, 10003 C\u00e1ceres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3405-8801","authenticated-orcid":false,"given":"David","family":"Risco","sequence":"additional","affiliation":[{"name":"Unidad de Histolog\u00eda y Anatom\u00eda Patol\u00f3gica, Departamento de Medicina Animal, Veterinary Faculty, University of C\u00e1ceres, Avenida de la Universidad s\/n, 10003 C\u00e1ceres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Byrne, A.W., Allen, A.R., O\u2019Brien, D.J., and Miller, M.A. (2019). 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