{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T16:53:48Z","timestamp":1789923228486,"version":"4.0.1"},"reference-count":97,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T00:00:00Z","timestamp":1736121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Rubella Virus, Cytomegalovirus (CMV), Herpes Simplex Virus-2 (HSV-2), Hepatitis B (HBV) and Hepatitis C virus (HCV) can cause serious fetal disease. The seropositivity rates of these agents vary among countries and geographic regions. This study aimed to analyze the prevalence rates and diagnostic methods used in studies investigating the seroprevalence of viral pathogens in the TORCH group among pregnant women in Turkey between 2005 and 2024. A systematic search was conducted using electronic databases between January 2005 and January 2024. A total of 60 studies meeting the inclusion criteria were included. Data quality control was assessed using the Joanna Briggs Institute guideline prevalence studies checklist. Heterogeneity was measured using the I-squared (I2) statistic in the Comprehensive Meta Analysis (CMA) program. The average seropositivity rates for Rubella, CMV, HSV-2, HBV and HCV in Turkey were determined as 91.18%, 94.81%, 35.52%, 1.66% and 0.25%, respectively. When the diagnostic methods were examined, it was determined that ELISA and ECLIA methods were used most frequently. The seropositivity of the agents did not show statistically significant differences according to the year periods, geographical regions and age of the patients (p &gt; 0.05). The highest prevalence rates of Rubella and HSV-2 in pregnant women were reported in the Mediterranean region, the highest prevalence rates of CMV and HCV in the Southeastern Anatolia region and the highest seroprevalence of Anti HBs in the Marmara region. The results of this study support the necessity of increasing public awareness in the control of fetal infection caused by TORCH viral agents, prenatal screening, vaccination for Rubella and HBV and compliance with hygiene conditions for agents such as CMV, HSV-2 and HCV. The results of this study highlight the need to increase public awareness on prenatal screening for the control of fetal infection caused by all TORCH viral agents, vaccination for Rubella and HBV and compliance with hygiene conditions for agents such as CMV, HSV-2 and HCV.<\/jats:p>","DOI":"10.3390\/pathogens14010037","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T08:08:52Z","timestamp":1736150932000},"page":"37","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Seroprevalence of TORCH Viral Agents in Pregnant Women in Turkey: Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1348-625X","authenticated-orcid":false,"given":"Elmas Pinar","family":"Kahraman Kilbas","sequence":"first","affiliation":[{"name":"Department of Medical Laboratory Techniques, Health Services Vocational School, Fenerbahce University, 34758 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ihsan Hakki","family":"Ciftci","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine, Sakarya University, 54100 Sakarya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imdat","family":"Kilbas","sequence":"additional","affiliation":[{"name":"Medical Microbiology Doctorate Program, Institute of Health Sciences, Istanbul University, 34093 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hande","family":"Toptan","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine, Sakarya University, 54100 Sakarya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/aji.12355","article-title":"Viral infections during pregnancy","volume":"73","author":"Silasi","year":"2015","journal-title":"Am. J. Reprod. Immunol."},{"key":"ref_2","first-page":"154","article-title":"Comparison of enzyme linked immunosorbent assay and indirect haemagglutination test in serologic diagnosis of toxoplasmosis","volume":"23","author":"Malhotra","year":"1991","journal-title":"J. Commun. Dis."},{"key":"ref_3","first-page":"61","article-title":"Investigation of Toxoplasma gondii antibodies with ELISA among women of childbearing age in Sanliurfa province: A three years evaluation","volume":"3","author":"Duygu","year":"2012","journal-title":"J. Clin. Exp. Immunol."},{"key":"ref_4","first-page":"169","article-title":"Rubella immunity in pregnant Iranian women: A systematic review and meta-analysis","volume":"13","author":"Azami","year":"2019","journal-title":"Int. J. Fertil. Steril."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1080\/21645515.2020.1729027","article-title":"Sero-prevalence of rubella among pregnant women in Sub-Saharan Africa: A meta-analysis","volume":"16","author":"Kassa","year":"2020","journal-title":"Hum. Vaccin. Immunother."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.15585\/mmwr.mm6544a6","article-title":"Progress toward regional measles elimination-worldwide, 2000\u20132015","volume":"65","author":"Patel","year":"2016","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s13052-017-0358-8","article-title":"Congenital cytomegalovirus infection: Advances and challenges in diagnosis, prevention, and treatment","volume":"43","author":"Marsico","year":"2017","journal-title":"Ital. J. Pediatr."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1055\/s-0034-1385854","article-title":"Congenital disseminated HSV-1 infection in preterm twins after primary gingivostomatitis of the mother: Case report and review of the literature","volume":"218","author":"Mercolini","year":"2014","journal-title":"Z. Geburtshilfe Neonatol."},{"key":"ref_9","first-page":"175A","article-title":"Preventing herpes simplex virus transmission to the neonate","volume":"11","author":"Brown","year":"2004","journal-title":"Herpes"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1093\/cid\/ciy562","article-title":"The epidemiology of herpes simplex virus type 1 in Asia: Systematic review, meta-analyses, and meta-regressions","volume":"68","author":"Khadr","year":"2019","journal-title":"Clin. Infect. Dis."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.2147\/IDR.S359113","article-title":"Intrauterine infection and mother-to-child transmission of hepatitis B virus: Route and molecular mechanism","volume":"15","author":"Zhao","year":"2022","journal-title":"Infect. Drug Resist."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jceh.2019.02.007","article-title":"Indian National Association for the Study of the Liver-Federation of Obstetric and Gynaecological Societies of India Position Statement on management of liver diseases in pregnancy","volume":"9","author":"Arora","year":"2019","journal-title":"J. Clin. Exp. Hepatol."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Dibba, P., Cholankeril, R., and Li, A.A. (2018). Hepatitis C in pregnancy. Diseases, 6.","DOI":"10.3390\/diseases6020031"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1055\/s-0033-1334459","article-title":"Hepatitis C virus in pregnancy","volume":"30","author":"Prasad","year":"2013","journal-title":"Am. J. Perinatol."},{"key":"ref_15","unstructured":"World Health Organization (2024, December 14). Global HIV, Hepatitis and STIs Programmes for the Period 2022\u20132030. Available online: https:\/\/www.who.int\/teams\/global-hiv-hepatitis-and-stis-programmes\/strategies\/global-health-sector-strategies."},{"key":"ref_16","unstructured":"Ministry of Health (2024, December 14). National Guideline for Prevention of Mother-to-Child Transmission of HIV, Syphilis and Hepatitis B Virus. Available online: https:\/\/www.prepwatch.org\/wp-content\/uploads\/2022\/07\/National-Guideline-for-Prevention-of-Mother-to-child-Transmission-of-HIV-Syphilis-and-Hepatitis-B-Virus-2021.pdf."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1002\/jmv.22017","article-title":"Prevalence, risk factors and virological profile of chronic Hepatitis B virus infection in pregnant women in India","volume":"83","author":"Pande","year":"2011","journal-title":"J. Med. Virol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Wondmeneh, T.G., and Mekonnen, A.T. (2024). Epidemiology of Hepatitis B virus infection among pregnant women in Africa: A systematic review and meta-analysis. BMC Infect. Dis., 24.","DOI":"10.1186\/s12879-024-09839-3"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jceh.2017.12.001","article-title":"INASL position statements on prevention, diagnosis and management of Hepatitis B virus infection in India: The Andaman statements","volume":"8","author":"Arora","year":"2018","journal-title":"J. Clin. Exp. Hepatol."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Lowe, R., Barcellos, C., Brasil, P., Cruz, O.G., Hon\u00f3rio, N.A., Kuper, H., and Carvalho, M.S. (2018). The Zika virus epidemic in Brazil: From discovery to future implications. Int. J. Environ. Res. Public Health, 15.","DOI":"10.3390\/ijerph15010096"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"k4431","DOI":"10.1136\/bmj.k4431","article-title":"Maternal-fetal transmission and adverse perinatal outcomes in pregnant women infected with Zika virus: Prospective cohort study in French Guiana","volume":"363","author":"Pomar","year":"2018","journal-title":"BMJ"},{"key":"ref_22","first-page":"e34SP112","article-title":"Pregnant women\u2019s perceptions on information sources on Zika virus: A qualitative study","volume":"34","author":"Petra","year":"2024","journal-title":"Physis"},{"key":"ref_23","unstructured":"Centers for Disease Control and Prevention (2024, December 14). Zika Virus. Zika Travel Information, Available online: https:\/\/wwwnc.cdc.gov\/travel\/page\/zika-travel-information."},{"key":"ref_24","first-page":"372n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Aromataris, E., and Munn, Z. (2020). Chapter 5: Systematic reviews of prevalence and incidence. JBI Manual for Evidence Synthesis, JBI.","DOI":"10.46658\/JBIRM-17-01"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/00365540600978880","article-title":"Seroprevalence of Toxoplasma gondii, rubella and cytomegalovirus among pregnant women in southern Turkey","volume":"39","author":"Ocak","year":"2007","journal-title":"Scand. J. Infect. Dis."},{"key":"ref_27","first-page":"451","article-title":"Prevalence of rubella and cytomegalovirus antibodies among pregnant women in northern Turkey","volume":"31","author":"Uyar","year":"2008","journal-title":"New Microbiol."},{"key":"ref_28","first-page":"1","article-title":"The prevalence of Hepatitis B, Hepatitis C, HIV, toxoplasmosis and rubella among pregnant women delivered in our clinic between 2000 and 2005","volume":"40","author":"Dundar","year":"2009","journal-title":"Zeynep Kamil Tip Bulteni"},{"key":"ref_29","first-page":"6","article-title":"Van yoresindeki gebelerde sitomegalovirus, rubella ve toksoplazma antikorlarinin seroprevalansi","volume":"16","author":"Efe","year":"2009","journal-title":"Van Tip Derg."},{"key":"ref_30","first-page":"21","article-title":"Evaluation of rubella, toxoplasma gondii, and cytomegalovirus seroprevalences among pregnant women in Denizli province","volume":"41","author":"Karabulut","year":"2011","journal-title":"Turk. J. Med. Sci."},{"key":"ref_31","first-page":"78","article-title":"Investigation of viral pathogens during pregnancy in a city region in Turkey","volume":"5","author":"Ozdemir","year":"2011","journal-title":"AJCI"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"128","DOI":"10.5505\/ptd.2013.40469","article-title":"Afyon bolgesinde gebelerde toksoplazma ve rubella seroprevalansi","volume":"6","author":"Asik","year":"2013","journal-title":"Pam. Tip Derg."},{"key":"ref_33","first-page":"123","article-title":"Toxoplasma, Rubella, CMV, HBV, AntiHBs, HCV, HIV seroprevalence in first trimester pregnant women","volume":"29","author":"Keskin","year":"2013","journal-title":"Selcuk Tip Derg."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"326","DOI":"10.5798\/diclemedj.0921.2014.02.0425","article-title":"Seroprevalence of Toxoplasma gondii, rubella and cytomegalovirus among pregnant women","volume":"41","author":"Bakacak","year":"2014","journal-title":"Dicle Tip Derg."},{"key":"ref_35","first-page":"19","article-title":"Bir devlet hastanesinde gebe kadinlarda toksoplasma, rubella ve sitomegalovirus seroprevalansinin arastirilmasi","volume":"7","author":"Inci","year":"2014","journal-title":"Pam. Tip Derg."},{"key":"ref_36","first-page":"228","article-title":"Gebelerde Toxoplasma gondii, Rubella, Sitomegalovirus, Sifiliz ve Hepatit B seropozitiflik oranlar\u0131","volume":"38","author":"Ozel","year":"2014","journal-title":"Turkiye Parazitol Derg."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1007\/s00404-014-3340-3","article-title":"Screening cytomegalovirus, rubella and toxoplasma infections in pregnant women with unknown pre-pregnancy serological status","volume":"290","author":"Karacan","year":"2014","journal-title":"Arch. Gynecol. Obstet."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"90","DOI":"10.5222\/iksst.2014.090","article-title":"Seroprevalence of Rubella, Cytomegalovirus and Toxoplasma antibodies among pregnant women that referred to Sorgun State Hospital","volume":"6","author":"Yapca","year":"2014","journal-title":"Istanbul Kanuni Sultan Suleyman Tip Dergisi"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"79","DOI":"10.4274\/tjod.35902","article-title":"Seroprevalence of Toxoplasma, Rubella, and Cytomegalovirus among pregnant women in Van","volume":"12","author":"Parlak","year":"2015","journal-title":"Turk. J. Obstet. Gynecol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1179\/2295333715Y.0000000021","article-title":"Seroprevalence of Toxoplasma gondii, rubella and Cytomegalovirus among pregnant females in north-western Turkey","volume":"70","author":"Aynioglu","year":"2015","journal-title":"Acta Clin. Belg."},{"key":"ref_41","first-page":"203","article-title":"TORCH seroprevalence among patients attending Obstetric Care Clinic of Haydarpasa Training and Research Hospital affiliated to Association of Istanbul Northern Anatolia Public Hospitals","volume":"2","author":"Numan","year":"2015","journal-title":"North Clin. Istanb."},{"key":"ref_42","unstructured":"Ozdemir, M., Esenkaya Tasbent, F., Terzi, H.A., Cetinkol, Y., Uysal, E.B., Asik, G., Parlak, M., Gulhan, B., and Ciftci, I.H. (2016). Seroprevalence of major viral pathogens during pregnancy: A multicenter study in Turkey. Adv. Clin. Med. Microbiol., 1."},{"key":"ref_43","first-page":"1","article-title":"Afyon Kocatepe Universitesi, Arastirma ve Uygulama Hastanesinde takip edilen gebelerde Toksoplazma, Rubella, Sitomegalovirus ve Herpes Simpleks Virus Tip 2 seroprevalansinin incelenmesi","volume":"8","author":"Simsek","year":"2016","journal-title":"Ortadogu Med. J.\/Ortadogu Tip Derg."},{"key":"ref_44","first-page":"242","article-title":"Dogu Karadeniz Bolgesi\u2019ndeki gebe kadinlarda Rubella virus seroprevalansi","volume":"23","author":"Senturk","year":"2016","journal-title":"Van T\u0131p Derg."},{"key":"ref_45","first-page":"11","article-title":"Gebe Kadinlarda Rubella ve Sitomegalovirus seroprevalansinin ELISA yontemi ile arastirilmasi","volume":"6","author":"Akpinar","year":"2017","journal-title":"Balikesir Saglik Bilimleri Dergisi"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"727","DOI":"10.15537\/smj.2017.7.18182","article-title":"Seroprevalence of Toxoplasma gondii, Rubella virus and Cytomegalovirus among pregnant women and the importance of avidity assays","volume":"38","author":"Sirin","year":"2017","journal-title":"Saudi Med. J."},{"key":"ref_47","first-page":"31","article-title":"Mugla\u2019daki gebelerin Toksoplazma, Rubella, Sitomegalovirus ve Hepatit prevalansinin degerlendirilmesi","volume":"27","author":"Kasap","year":"2017","journal-title":"Izmir Tepecik Egitim ve Arastirma Hastanesi Dergisi"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"7","DOI":"10.2399\/prn.18.0261004","article-title":"Investigation of toxoplasma, cytomegalovirus and rubella seroprevalence in pregnant women admitted to our hospital","volume":"26","author":"Madendag","year":"2018","journal-title":"Perinatal J."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"74","DOI":"10.21613\/GORM.2019.903","article-title":"Antenatal Toxoplasma Gondii, Rubella and Cytomegalovirus infection screening among pregnant women attending tertiary university hospital","volume":"25","author":"Gurlek","year":"2019","journal-title":"Gynecol. Obstet. Reprod. Med."},{"key":"ref_50","first-page":"211","article-title":"Hastanemize basvuran gebelerde Toksoplazma, Rubella Virus ve Sitomegalovirus enfeksiyonlari icin serolojik gostergelerin degerlendirilmesi","volume":"50","author":"Cubuk","year":"2020","journal-title":"Turk. Mikrobiyol. Cemiy. Derg."},{"key":"ref_51","first-page":"326","article-title":"Prevalence of serum antibodies to Toxoplasma, Rubella, Cytomegalovirus among pregnant women","volume":"10","author":"Guzel","year":"2020","journal-title":"Duzce Universitesi Saglik Bilimleri Enstitusu Dergisi"},{"key":"ref_52","first-page":"22","article-title":"Seroprevalence rates of Toxoplasma gondii, Rubella, Cytomegalovirus among first trimester pregnant women in Istanbul","volume":"10","author":"Ozel","year":"2021","journal-title":"Int. J. Reprod. Contracept. Obstet. Gynecol."},{"key":"ref_53","first-page":"3","article-title":"Seroprevalence of Toxoplasma gondii, Rubella and Cytomegalovirus in the Southeastern Turkey and the current approach","volume":"39","author":"Uzun","year":"2022","journal-title":"Actual Quest. Mod. Gynecol. Perinatol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"202","DOI":"10.38053\/acmj.1062754","article-title":"Rubella, Cytomegalovirus and toxoplasmosis seroprevalence in pregnants in Corum Province","volume":"4","author":"Kahraman","year":"2022","journal-title":"Anatolian Curr. Med. J."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"171","DOI":"10.38175\/phnx.1289083","article-title":"Gebelerde Toxoplasma gondii, Rubella ve Sitomegalovirus seroprevalansi: Ulke geneli cok merkezli calisma","volume":"5","author":"Kul","year":"2023","journal-title":"Phoenix Med. J."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"719","DOI":"10.19127\/bshealthscience.1355918","article-title":"Kafkas Universitesi Saglik Arastirma ve Uygulama Hastanesi\u2019ne basvuran dogurganlik yas grubundaki kadinlarda Toxoplasma gondii, Rubella ve Sitomegalovirus seropozitifligi: Uc yillik degerlendirme","volume":"6","author":"Ozgur","year":"2023","journal-title":"Black Sea J. Health Sci."},{"key":"ref_57","first-page":"29","article-title":"Seroprevalence of Toxoplasma Gondii, Rubella and Cytomegalovirus among pregnant women in our clinic","volume":"10","author":"Kinci","year":"2023","journal-title":"Med. J. Mugla Sitki Kocman Univ."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"28","DOI":"10.54453\/TMCD.2023.44827","article-title":"Konya ili Meram Tip Fakultesi Hastanesi\u2019ne basvuran hamilelerde enzyme linked fluorescent assay yontemiyle tespit edilen Toxoplasma gondii, Rubella, Sitomegalovirus seroprevalansi","volume":"53","author":"Ezer","year":"2023","journal-title":"Turk. Mikrobiyol. Cemiy. Derg."},{"key":"ref_59","first-page":"5304","article-title":"Screening of cytomegalovirus seroprevalence among pregnant women in Ankara, Turkey: A controversy in prenatal care","volume":"5","author":"Oruc","year":"2011","journal-title":"Afr. J. Microbiol. Res."},{"key":"ref_60","first-page":"19","article-title":"Investigation of seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in pregnant population in Istanbul","volume":"5","author":"Alacam","year":"2020","journal-title":"JAMER"},{"key":"ref_61","first-page":"106","article-title":"Asymptomatic herpes simplex virus type 2 (HSV-2) infection among pregnant women in Turkey","volume":"120","author":"Duran","year":"2004","journal-title":"Indian J. Med. Res."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1111\/j.1468-3083.2006.01766.x","article-title":"Seroprevalence of herpes simplex virus type 1 and type 2 in Turkey","volume":"20","author":"Dolar","year":"2006","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1055\/a-0842-6941","article-title":"Herpes Simplex infection during pregnancy, results of a tertiary referral center in Turkey","volume":"224","author":"Sert","year":"2020","journal-title":"Z Geburtshilfe Neonatol."},{"key":"ref_64","first-page":"369","article-title":"Kisa bildiri: Sanliurfa Kadin Hastaliklari ve Dogum Hastanesine basvuran kadinlarda Hepatit B, Hepatit C ve insan immun yetmezlik virusu seropozitifligi","volume":"40","author":"Tekay","year":"2006","journal-title":"Mikrobiyol. Bul."},{"key":"ref_65","first-page":"191","article-title":"Adiyaman\u2019da gebe kadinlarda HBsAg ve Anti-HCV sikligi","volume":"36","author":"Kolgelier","year":"2009","journal-title":"Dicle Tip Dergisi"},{"key":"ref_66","first-page":"146","article-title":"Seroprevalence of Hepatitis B Virus among pregnant women in Northern Turkey","volume":"9","author":"Uyar","year":"2009","journal-title":"Hepat. Mon."},{"key":"ref_67","first-page":"9","article-title":"HBsAg, Anti-HBs, Anti-HCV and Anti-HIV seroprevalence in pregnant women living in Turkey","volume":"3","author":"Guckan","year":"2016","journal-title":"Asian Pac. J. Nurs."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"3942","DOI":"10.5897\/AJMR11.675","article-title":"An unexpected low Hepatitis B seroprevalence in pregnant women from the rural Southeastern Turkey","volume":"5","author":"Yavuzcan","year":"2011","journal-title":"Afr. J. Microbiol. Res."},{"key":"ref_69","first-page":"15","article-title":"Hepatitis B and Hepatitis C seropositivities in women admitted to Gynecology and Obstetrics Hospital in Sanliurfa City: A 3-Year Evaluation","volume":"18","author":"Duygu","year":"2012","journal-title":"Viral Hepat. J."},{"key":"ref_70","first-page":"166","article-title":"Ucuncu basamak bir hastanedeki gebe ve\/veya jinekolojik hastalikli kadinlarda HBsAg, Anti-HCV ve Anti-HIV sikligi","volume":"4","author":"Ozlu","year":"2013","journal-title":"J. Clin. Exp. Investig."},{"key":"ref_71","first-page":"254","article-title":"Rize bolgesinde yasayan gebe kadinlarda HBsAg, Anti-HBs ve Anti-HCV seroprevalansi","volume":"40","author":"Balik","year":"2013","journal-title":"Dicle Tip Dergisi"},{"key":"ref_72","first-page":"1","article-title":"Kirikkale bolgesinde yasayan gebelerde Hepatit B ve Hepatit C seropozitiflik oranlari","volume":"5","author":"Gul","year":"2015","journal-title":"Bozok Tip Dergisi"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1136\/postgradmedj-2015-133876","article-title":"Changes in the prevalence of HBV infection in pregnant women in Turkey between 1995 and 2015: A 20-year evaluation","volume":"92","author":"Furuncuoglu","year":"2016","journal-title":"Postgrad. Med. J."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"120","DOI":"10.5578\/flora.64056","article-title":"Ege Universitesi Tip Fakultesi Hastanesinde gebelerde HBsAg, Anti-HIV1\/2 ve Anti-HCV seroprevalansi","volume":"22","year":"2017","journal-title":"FLORA"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"904","DOI":"10.3855\/jidc.10018","article-title":"Seroprevalence of hepatitis B surface antigen and associated risk factors among pregnant women","volume":"12","author":"Cetin","year":"2018","journal-title":"J. Infect. Dev. Ctries"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4274\/vhd.0010","article-title":"Seroprevalence of Hepatitis B Surface Antigen, Anti-Hepatitis B Surface and Anti-Hepatitis C Virus among pregnant women residing in Sirnak province","volume":"24","author":"Sahin","year":"2018","journal-title":"Viral Hepat. J."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"260","DOI":"10.5152\/tjg.2018.17634","article-title":"Seroprevalence of hepatitis B, hepatitis C, and HIV in pregnant women from Eastern Turkey","volume":"30","author":"Ozkurt","year":"2019","journal-title":"Turk. J. Gastroenterol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"95","DOI":"10.4274\/tjod.galenos.2019.15564","article-title":"Comparison of hepatitis B, hepatitis C, and HIV seropositivity of Syrian and Turkish pregnant women","volume":"16","author":"Turan","year":"2019","journal-title":"Turk. J. Obstet. Gynecol."},{"key":"ref_79","first-page":"89","article-title":"Hepatitis B, Hepatitis C and HIV Seroprevalence in pregnant women: Six years of experience","volume":"2","author":"Kale","year":"2020","journal-title":"Turk. J. Womens Health Neonatol."},{"key":"ref_80","first-page":"156","article-title":"Gebelerde HBsAg ve Anti-HCV Seroprevalansi ile hepatit b bagisikliginin degerlendirilmesi: Tanimlayici calisma","volume":"5","author":"Oner","year":"2021","journal-title":"Med. J. West Black Sea"},{"key":"ref_81","first-page":"359","article-title":"Prevalence of HBsAg seropositivity during pregnancy and evaluation of vaccination programs: A multicenter study in Turkey","volume":"8","author":"Bilman","year":"2021","journal-title":"North Clin. Istanb."},{"key":"ref_82","first-page":"507","article-title":"Trabzon ilinde gebelerde Hepatit B, Hepatit C, HIV ve RPR seropozitifligi","volume":"10","author":"Erin","year":"2021","journal-title":"Gumushane Universitesi Saglik Bilimleri Dergisi."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"14","DOI":"10.4274\/vhd.galenos.2021.2020-12-9","article-title":"A Study of the Hepatitis B frequency and its possible adverse outcomes on pregnancy at a university hospital","volume":"28","author":"Gulseren","year":"2022","journal-title":"Viral Hepat. J."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"e20221446","DOI":"10.1590\/1806-9282.20221446","article-title":"Comparison of Hepatitis B surface antigen, Anti-Hepatitis B surface, and Anti-Hepatitis C Virus prevalence in Syrian refugee pregnant women and Turkish pregnant women","volume":"69","author":"Hansu","year":"2023","journal-title":"Rev. Assoc. Med. Bras."},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Nasimi, A., Fani, M., Salehi, M., Ghasemi, H., Nezami, H., and Haghighi, F.H. (2021). Seroprevalence of Toxoplasma gondii, Rubella and Cytomegalovirus among women of reproductive age in Mashhad, Northeast of Iran. Res. Sq., 1\u201314.","DOI":"10.21203\/rs.3.rs-1184788\/v1"},{"key":"ref_86","first-page":"119","article-title":"Gebelerde Sitomegalovirus seroprevalansi ve Turkiye\u2019nin dunyadaki seroepidemiyolojik durumu; bir meta-analiz arastirmasi","volume":"24","author":"Cetinkaya","year":"2019","journal-title":"FLORA"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1093\/eurpub\/ckw259","article-title":"Global seroprevalence of Rubella among pregnant and childbearing age women: A meta-analysis","volume":"27","author":"Pandolfi","year":"2017","journal-title":"Eur. J. Public Health"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"101101","DOI":"10.1016\/j.ajogmf.2023.101101","article-title":"Treatment with valacyclovir during pregnancy for prevention of congenital cytomegalovirus infection: A real-life multicenter Italian observational study","volume":"5","author":"Zammarchi","year":"2023","journal-title":"Am. J. Obstet. Gynecol. MFM"},{"key":"ref_89","first-page":"179","article-title":"TORCH infection status in women of childbearing age in China: A meta-analysis","volume":"7","author":"Wang","year":"2023","journal-title":"J. Clin. Nurs. Res."},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"Radoi, C.L., Cristea, O.M., Vulcanescu, D.D., Voinescu, A., Dragomir, T.L., Sima, L.V., Tanasescu, S., Harich, O.O., Balasoiu, A.T., and Iliescu, D.G. (2024). Seroprevalence of Herpes Simplex Virus Types 1 and 2 among pregnant women in South-Western Romania. Life, 14.","DOI":"10.3390\/life14050596"},{"key":"ref_91","unstructured":"Berghella, V. (2009). Maternal-Fetal Tip Kanita Dayali Klinik Kilavuzlar. Maternal-Fetal Evidence Based Guidelines, Istanbul Medikal Yayincilik."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1016\/j.jceh.2022.08.005","article-title":"Seroprevalence of hepatitis B virus among pregnant women in India: A systematic review and meta-analysis","volume":"12","author":"Giri","year":"2022","journal-title":"J. Clin. Exp. Hepatol."},{"key":"ref_93","doi-asserted-by":"crossref","unstructured":"Larebo, Y.M., Anshebo, A.A., Abdo, R.A., Behera, S.K., and Gopalan, N. (2024). Prevalence of hepatitis B virus infection among pregnant women in Africa: A systematic review and meta-analysis. PLoS ONE, 19.","DOI":"10.1371\/journal.pone.0305838"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4274\/vhd.30932","article-title":"Seroepidemiology of Hepatitis B Virus infection in Istanbul: A 20-year survey","volume":"22","author":"Furuncuoglu","year":"2016","journal-title":"Viral Hepat. J."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1365-2893.2010.01413.x","article-title":"Hepatitis C virus infection during pregnancy and the newborn period: Are they opportunities for treatment?","volume":"18","author":"Arshad","year":"2011","journal-title":"J. Viral Hepat."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"B2","DOI":"10.1016\/j.ajog.2017.07.039","article-title":"Hepatitis C in pregnancy: Screening, treatment, and management","volume":"217","author":"Hughes","year":"2017","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_97","first-page":"142","article-title":"Healthcare related risk factors account for the majority of HCV transmissions in Middle Black Sea region of Turkey: A Case-Control Study","volume":"31","author":"Barut","year":"2011","journal-title":"Turk. Klin. J. Med. Sci."}],"container-title":["Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-0817\/14\/1\/37\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:23:37Z","timestamp":1759919017000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-0817\/14\/1\/37"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,6]]},"references-count":97,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1]]}},"alternative-id":["pathogens14010037"],"URL":"https:\/\/doi.org\/10.3390\/pathogens14010037","relation":{},"ISSN":["2076-0817"],"issn-type":[{"value":"2076-0817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,6]]}}}