{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T16:36:14Z","timestamp":1763829374500,"version":"build-2065373602"},"reference-count":19,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Grant Funding Project 2023\u20132025 of the Science Committee of Science, Ministry of Science and Higher Education of the Republic of Kazakhstan","award":["AP19679451"],"award-info":[{"award-number":["AP19679451"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Antiseptics are essential in infection control within veterinary medicine and are widely used for wound care, dermatological treatments, and disinfection. Growing interest in eco-friendly antiseptics has led to research on natural formulations. The aim of this study is to evaluate the efficacy and safety of natural antiseptic agents in combating pathogenic microorganisms and their use in disinfection. This article presents the results of efficacy testing, particularly focusing on Shozan (anolyte + ozone + shungite), which demonstrated strong bactericidal activity against pathogenic bacteria such as Brucella melitensis, effectively inhibiting their growth across various concentrations and exposure times. In contrast, Shuprozan (anolyte + ozone + shungite + propolis) and Prozan (anolyte + ozone + propolis) did not exhibit significant antibacterial effects. No antiviral activity was detected against the lumpy skin disease virus and foot-and-mouth disease virus, and no fungicidal properties were observed against Trichophyton verrucosum and Histoplasma farciminosum. This study\u2019s results confirm the high efficacy and safety of natural antiseptics.<\/jats:p>","DOI":"10.3390\/pathogens14040321","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T04:11:40Z","timestamp":1743135100000},"page":"321","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Natural Antiseptics in Veterinary Practice: Evaluation of Efficacy and Safety"],"prefix":"10.3390","volume":"14","author":[{"given":"Askar","family":"Nametov","sequence":"first","affiliation":[{"name":"Institute of Veterinary and Agrotechnology, Zhangir Khan West Kazakhstan Agrarian Technical University, Zhangir Khan St. 51, Uralsk 090009, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2565-3107","authenticated-orcid":false,"given":"Rashid","family":"Karmaliyev","sequence":"additional","affiliation":[{"name":"Institute of Veterinary and Agrotechnology, Zhangir Khan West Kazakhstan Agrarian Technical University, Zhangir Khan St. 51, Uralsk 090009, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5161-5561","authenticated-orcid":false,"given":"Bakytkanym","family":"Kadraliyeva","sequence":"additional","affiliation":[{"name":"Institute of Veterinary and Agrotechnology, Zhangir Khan West Kazakhstan Agrarian Technical University, Zhangir Khan St. 51, Uralsk 090009, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenzhebek","family":"Murzabayev","sequence":"additional","affiliation":[{"name":"Institute of Veterinary and Agrotechnology, Zhangir Khan West Kazakhstan Agrarian Technical University, Zhangir Khan St. 51, Uralsk 090009, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Dushayeva","sequence":"additional","affiliation":[{"name":"Institute of Veterinary and Agrotechnology, Zhangir Khan West Kazakhstan Agrarian Technical University, Zhangir Khan St. 51, Uralsk 090009, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanat","family":"Orynkhanov","sequence":"additional","affiliation":[{"name":"Veterinary and Zooengineering Faculty, Kazakh National Agrarian Research University, Abay Ave. 8, Almaty 050010, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karagulov","family":"Adilbay","sequence":"additional","affiliation":[{"name":"Institute of Veterinary and Agrotechnology, Zhangir Khan West Kazakhstan Agrarian Technical University, Zhangir Khan St. 51, Uralsk 090009, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marat","family":"Magzhan","sequence":"additional","affiliation":[{"name":"Institute of Veterinary and Agrotechnology, Zhangir Khan West Kazakhstan Agrarian Technical University, Zhangir Khan St. 51, Uralsk 090009, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S93","DOI":"10.1086\/340246","article-title":"Antimicrobial Use and Resistance in Animals","volume":"34","author":"McEwen","year":"2002","journal-title":"Clin. 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