{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T23:46:06Z","timestamp":1787615166984,"version":"build-2736575974"},"reference-count":63,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T00:00:00Z","timestamp":1743120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Candida auris has emerged as a multidrug-resistant yeast implicated in healthcare-associated invasive infections and hospital outbreaks. The aim of the current 38-month period observational study in a multidisciplinary Intensive Care Unit (ICU) was to analyze the epidemiology, potential risk factors, management strategies, and patient outcomes of patients with C. auris. During the study period, 32 patients were identified with C. auris infection (6 patients) or colonization (26 patients) and their clinical characteristics and treatment-related factors were compared. Identification of C. auris isolates was confirmed by MALDI-TOF spectrometry. According to our results, regarding patient-related factors, no significant differences were identified. Regarding treatment-related factors, the proportion of patients already receiving corticosteroids (34.6% vs. 83.3%, p = 0.064) or being on renal replacement treatment (7.7% vs. 33.3%) was higher in infected patients. Median time elapsed from ICU admission to first positive culture was 7 (1\u201321) days and half of cases were ICU-imported. All strains were resistant to fluconazole and susceptible to echinocandines and amphotericin B. Crude mortality of the study population was 43.75%, similar to other previously reported candidemias. Rapid identification of C. auris, continued surveillance, and infection control practices are important elements for controlling successfully its spread in the hospital setting and for establishing promptly its transition from commensalism to infection.<\/jats:p>","DOI":"10.3390\/pathogens14040328","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T06:45:51Z","timestamp":1743144351000},"page":"328","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Impact of Candida auris on Critically Ill Patients: A Three-Year Observational Study in a Greek Intensive Care Unit"],"prefix":"10.3390","volume":"14","author":[{"given":"Maria","family":"Katsiari","sequence":"first","affiliation":[{"name":"Intensive Care Unit, Konstantopouleio-Patision General Hospital, 3-5 Theodorou Konstantopoulou Street, N. Ionia, 14233 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charikleia","family":"Nikolaou","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Konstantopouleio-Patision General Hospital, 3-5 Theodorou Konstantopoulou Street, N. Ionia, 14233 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleftheria","family":"Palla","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Konstantopouleio- Patision General Hospital, 3-5 Theodorou Konstantopoulou Street, N. Ionia, 14233 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalliopi","family":"Theodoridou","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0656-4715","authenticated-orcid":false,"given":"Athanasios","family":"Tsakris","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4766-8238","authenticated-orcid":false,"given":"Georgia","family":"Vrioni","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1348-0421.2008.00083.x","article-title":"Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital","volume":"53","author":"Satoh","year":"2009","journal-title":"Microbiol. Immunol."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Chowdhary, A., Sharma, C., and Meis, J.F. (2017). Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally. PLoS Pathog., 13.","DOI":"10.1371\/journal.ppat.1006290"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jhin.2016.08.004","article-title":"Multidrug-resistant Candida auris: \u2018new kid on the block\u2019 in hospital-associated infections?","volume":"94","author":"Chowdhary","year":"2016","journal-title":"J. Hosp. Infect."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/cid\/ciw691","article-title":"Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses","volume":"64","author":"Lockhart","year":"2017","journal-title":"Clin. Infect. Dis."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"100878","DOI":"10.1016\/S2666-5247(24)00101-0","article-title":"Detection and characterisation of a sixth Candida auris clade in Singapore: A genomic and phenotypic study","volume":"5","author":"Suphavilai","year":"2024","journal-title":"Lancet Microbe"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e03364-19","DOI":"10.1128\/mBio.03364-19","article-title":"Tracing the evolutionary history and global expansion of Candida auris using population genomic analyses","volume":"11","author":"Chow","year":"2020","journal-title":"mBio"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/ajt.14121","article-title":"Investigation of the first seven reported cases of Candida auris, a globally emerging invasive, multidrug-resistant fungus-United States, May 2013\u2013August 2016","volume":"17","author":"Vallabhaneni","year":"2017","journal-title":"Am. J. Transplant."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2302843","DOI":"10.1080\/22221751.2024.2302843","article-title":"Candida auris-associated hospitalizations and outbreaks, China, 2018\u20132023","volume":"13","author":"Bing","year":"2024","journal-title":"Emerg. Microbes Infect."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.1128\/JCM.00319-11","article-title":"First three reported cases of nosocomial fungemia caused by Candida auris","volume":"49","author":"Lee","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1099\/jmm.0.048785-0","article-title":"Invasive candidiasis in Pakistan: Clinical characteristics, species distribution and antifungal susceptibility","volume":"62","author":"Farooqi","year":"2013","journal-title":"J. Med. Microbiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"S79","DOI":"10.1093\/ofid\/ofy358","article-title":"Twenty years of the SENTRY antifungal surveillance program: Results for Candida species from 1997\u20132016","volume":"6","author":"Pfaller","year":"2019","journal-title":"Open Forum Infect. Dis."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e00458-19","DOI":"10.1128\/mSphere.00458-19","article-title":"Combined antifungal resistance and biofilm tolerance: The global threat of Candida auris","volume":"4","author":"Kean","year":"2019","journal-title":"mSphere"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2996","DOI":"10.1128\/JCM.00921-17","article-title":"Survival, persistence, and isolation of the emerging multidrug-resistant pathogenic yeast Candida auris on a plastic health care surface","volume":"55","author":"Welsh","year":"2017","journal-title":"J. Clin. Microbiol."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Cosio, T., Pica, F., Fontana, C., Pistoia, E.S., Favaro, M., Valsecchi, I., Zarabian, N., Campione, E., Botterel, F., and Gaziano, R. (2024). Stephanoascus ciferrii Complex: The Current State of Infections and Drug Resistance in Humans. J. Fungi, 10.","DOI":"10.3390\/jof10040294"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Magr\u00ec, C., De Carolis, E., Ivagnes, V., Di Pilato, V., Spruijtenburg, B., Marchese, A., Meijer, E.F.J., Chowdhary, A., and Sanguinetti, M. (2024). \u201cCLADE-FINDER\u201d: Candida auris Lineage Analysis Determination by Fourier Transform Infrared Spectroscopy and Artificial Neural Networks. Microorganisms, 12.","DOI":"10.3390\/microorganisms12112153"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e01503","DOI":"10.1128\/JCM.01503-19","article-title":"Laboratory analysis of an outbreak of Candida auris in New York from 2016 to 2018: Impact and lessons learned","volume":"58","author":"Zhu","year":"2020","journal-title":"J. Clin. Microbiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1056\/NEJMoa1714373","article-title":"A Candida auris outbreak and its control in an Intensive Care Setting","volume":"379","author":"Eyre","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"ref_18","unstructured":"Edwards, J.E., Dolin, R., and Blaser, M.J. (2015). Mandell, Douglas, and Bennett\u2019s Principles and Practice of Infectious Diseases, Elsevier. [8th ed.]."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1128\/JCM.00367-15","article-title":"Multidrug-Resistant Candida auris Misidentified as Candida haemulonii: Characterization by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and DNA sequencing and its antifungal susceptibility profile variability by Vitek 2, CLSI broth microdilution, and Etest method","volume":"53","author":"Kathuria","year":"2015","journal-title":"J. Clin. Microbiol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"e00189-16","DOI":"10.1128\/mSphere.00189-16","article-title":"Comparative Pathogenicity of United Kingdom isolates of the emerging pathogen Candida auris and other key pathogenic Candida species","volume":"1","author":"Borman","year":"2016","journal-title":"mSphere"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.4014\/jmb.1609.09012","article-title":"Identification of uncommon Candida species using commercial identification systems","volume":"26","author":"Kim","year":"2016","journal-title":"J. Microbiol. Biotechnol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1128\/JCM.00630-17","article-title":"Rapid and accurate molecular identification of the emerging multidrug-resistant pathogen Candida auris","volume":"55","author":"Kordalewska","year":"2017","journal-title":"J. Clin. Microbiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"e01223-17","DOI":"10.1128\/JCM.01223-17","article-title":"Development and validation of a real-time PCR assay for rapid detection of Candida auris from surveillance samples","volume":"56","author":"Leach","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"e01337-18","DOI":"10.1128\/JCM.01337-18","article-title":"Direct detection of emergent fungal pathogen Candida auris in clinical skin swabs by SYBR Green-Based Quantitative PCR Assay","volume":"56","author":"Sexton","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1111\/myc.12817","article-title":"Evaluation of a new T2 Magnetic Resonance assay for rapid detection of emergent fungal pathogen Candida auris on clinical skin swab samples","volume":"61","author":"Sexton","year":"2018","journal-title":"Mycoses"},{"key":"ref_26","unstructured":"U.S.A Centers for Disease Control and Prevention (CDC) (2024, December 24). Candida auris Antifungal Susceptibility Testing and Interpretation, Available online: https:\/\/www.cdc.gov\/fungal\/candida-auris\/c-auris-antifungal.html."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e00334-18","DOI":"10.1128\/mSphere.00334-18","article-title":"Transcriptome assembly and profiling of Candida auris reveals novel insights into biofilm-mediated resistance","volume":"3","author":"Kean","year":"2018","journal-title":"mSphere"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1900400","DOI":"10.2807\/1560-7917.ES.2019.24.29.1900400","article-title":"Isolation of Candida auris from cystic fibrosis patient, Greece, April 2019","volume":"24","author":"Stathi","year":"2019","journal-title":"Eurosurveillance"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"key":"ref_30","unstructured":"The European Committee on Antimicrobial Susceptibility Testing (2025, February 04). Breakpoint Tables for Interpretation of MICs for Antifungal Agents, Version 11.0. Available online: http:\/\/www.eucast.org\/astoffungi\/clinicalbreakpointsforantifungals\/."},{"key":"ref_31","unstructured":"Politi, L. (2023). The European Programme for Intervention Epidemiology Training (EPIET), 2021 Cohort National Public Health Organization (NPHO), Greece European Centre for Disease Prevention and Control."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Katsiari, M., Mavroidi, A., Kesesidis, N., Palla, E., Zourla, K., Ntorlis, K., Konstantinidis, K., Laskou, M., Strigklis, K., and Sakkalis, A. (2023). Emergence of Clonally-Related South Asian Clade I Clinical Isolates of Candida auris in a Greek COVID-19 Intensive Care Unit. J. Fungi, 9.","DOI":"10.3390\/jof9020243"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.ajem.2024.07.062","article-title":"Candida auris: A focused review for emergency clinicians","volume":"84","author":"Long","year":"2024","journal-title":"Am. J. Emerg. Med."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Dennis, E.K., Chaturvedi, S., and Chaturvedi, V. (2021). So Many Diagnostic Tests, So Little Time: Review and Preview of Candida auris Testing in Clinical and Public Health Laboratories. Front. Microbiol., 12.","DOI":"10.3389\/fmicb.2021.757835"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"2694","DOI":"10.3201\/eid2611.203504","article-title":"Multidrug-resistant Candida auris infections in critically ill coronavirus disease patients, India, April\u2013July 2020","volume":"26","author":"Chowdhary","year":"2020","journal-title":"Emerg. Infect. Dis."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.cmi.2020.12.030","article-title":"Outbreak of Candida auris infection in a COVID-19 hospital in Mexico","volume":"27","year":"2021","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"56","DOI":"10.15585\/mmwr.mm7002e3","article-title":"Candida auris outbreak in a COVID-19 specialty care unit\u2014Florida, July\u2013August 2020","volume":"70","author":"Prestel","year":"2021","journal-title":"Morb. Mortal. Wkly. Rep."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e2836","DOI":"10.1093\/cid\/ciaa1595","article-title":"Candida auris: A latent threat to critically ill patients with coronavirus disease 2019","volume":"73","author":"Rodriguez","year":"2021","journal-title":"Clin. Infect. Dis."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"e00910-19","DOI":"10.1128\/mSphere.00910-19","article-title":"Candida auris forms high-burden biofilms in skin niche conditions and on porcine skin","volume":"5","author":"Horton","year":"2020","journal-title":"mSphere"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.ijantimicag.2018.05.007","article-title":"The comparative efficacy of antiseptics against Candida auris biofilms","volume":"52","author":"Kean","year":"2018","journal-title":"Int. J. Antimicrob. Agents"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s13756-016-0132-5","article-title":"First hospital outbreak of the globally emerging Candida auris in a European hospital","volume":"5","author":"Schelenz","year":"2016","journal-title":"Antimicrob. Resist. Infect. Control"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Yadav, A., Singh, A., Wang, Y., Hi van Haren, M., Singh, A., de Groot, T., Meis, J.F., Xu, J., and Chowdhary, A. (2021). Colonisation and transmission dynamics of Candida auris among chronic respiratory diseases patients hospitalised in a Chest Hospital, Delhi, India: A comparative analysis of whole genome sequencing and microsatellite typing. J. Fungi, 7.","DOI":"10.3390\/jof7020081"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Pandya, N., Cag, Y., Pandak, N., Pekok, A.U., Poojary, A., Ayoade, F., Fasciana, T., Giammanco, A., Caskurlu, H., and Rajani, D.P. (2021). International multicentre study of Candida auris infections. J. Fungi, 7.","DOI":"10.3390\/jof7100878"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/mmy\/myy054","article-title":"Candida auris: The recent emergence of a multidrug-resistant fungal pathogen","volume":"57","author":"Forsberg","year":"2019","journal-title":"Med. Mycol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.3201\/eid2907.221888","article-title":"Nationwide outbreak of Candida auris infections driven by COVID-19 hospitalizations, Israel, 2021\u20132022","volume":"29","author":"Biran","year":"2023","journal-title":"Emerg. Infect. Dis."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jcrc.2020.01.004","article-title":"Candida auris candidaemia in an intensive care unit-prospective observational study to evaluate epidemiology, risk factors, and outcome","volume":"57","author":"Shastri","year":"2020","journal-title":"J. Crit. Care"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.ijantimicag.2019.08.013","article-title":"Control of Candida auris in healthcare institutions: Outcome of an International Society for Antimicrobial Chemotherapy expert meeting","volume":"54","author":"Kenters","year":"2019","journal-title":"Int. J. Antimicrob. Agents"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1016\/j.cmi.2020.02.001","article-title":"A clinical predictive model of candidaemia by Candida auris in previously colonized critically ill patients","volume":"26","author":"Salavert","year":"2020","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1007\/s40121-022-00625-9","article-title":"Candida auris candidemia in critically ill, colonized patients: Cumulative incidence and risk factors","volume":"11","author":"Briano","year":"2022","journal-title":"Infect. Dis. Ther."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Sayeed, M.A., Farooqi, J., Jabeen, K., Awan, S., and Mahmood, S.F. (2019). Clinical spectrum and factors impacting outcome of Candida auris: A single center study from Pakistan. BMC Infect. Dis., 19.","DOI":"10.1186\/s12879-019-3999-y"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s40560-018-0342-4","article-title":"Epidemiology, clinical characteristics, resistance, and treatment of infections by Candida auris","volume":"6","author":"Cortegiani","year":"2018","journal-title":"J. Intensive Care"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"e00842-22","DOI":"10.1128\/mbio.00842-22","article-title":"Genomic diversity across Candida auris clinical isolates shapes rapid development of antifungal resistance in vitro and in vivo","volume":"13","author":"Burrack","year":"2022","journal-title":"mBio"},{"key":"ref_53","first-page":"334","article-title":"Recurrent candidemia and isolation of echinocandin-resistant Candida auris in a patient with a long-term central catheter","volume":"40","year":"2022","journal-title":"Enferm. Infecc. Microbiol. Clin. (Engl. Ed.)"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"ofz262","DOI":"10.1093\/ofid\/ofz262","article-title":"Development of high-level echinocandin resistance in a patient with recurrent Candida auris candidemia secondary to chronic candiduria","volume":"6","author":"Biagi","year":"2019","journal-title":"Open Forum Infect. Dis."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.chom.2023.02.010","article-title":"One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome","volume":"31","author":"Proctor","year":"2023","journal-title":"Cell Host Microbe"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Caballero, U., Kim, S., Eraso, E., Quind\u00f3s, G., Vozmediano, V., Schmidt, S., and Jauregizar, N. (2021). In vitro synergistic interactions of isavuconazole and echinocandins against Candida auris. Antibiotics, 10.","DOI":"10.3390\/antibiotics10040355"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"e314","DOI":"10.1016\/S2666-5247(20)30194-4","article-title":"Micafungin and amphotericin b synergy against Candida auris","volume":"1","author":"Jaggavarapu","year":"2020","journal-title":"Lancet Microbe"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s12281-023-00451-7","article-title":"Strategies to prevent transmission of Candida auris in healthcare settings","volume":"17","author":"Ahmad","year":"2023","journal-title":"Curr. Fungal Infect. Rep."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Chen, J., Tian, S., Han, X., Chu, Y., Wang, Q., Zhou, B., and Shang, H. (2020). Is the superbug fungus really so scary? A systematic review and meta-analysis of global epidemiology and mortality of Candida auris. BMC Infect. Dis., 20.","DOI":"10.1186\/s12879-020-05543-0"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.jinf.2019.09.007","article-title":"Candida auris outbreak: Mortality, interventions and cost of sustaining control","volume":"79","author":"Taori","year":"2019","journal-title":"J. Infect."},{"key":"ref_61","unstructured":"ECDC Rapid Risk Assessment (2020, August 20). Candida Auris in Healthcare Settings-Europe. European Centre for Disease Prevention and Control; Stockholm. Available online: https:\/\/www.ecdc.europa.eu\/sites\/default\/files\/documents\/RRA-Candida-auris-European-Union-countries.pdf."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1093\/cid\/cix744","article-title":"Approach to the investigation and management of patients with Candida auris, an emerging multidrug-resistant yeast","volume":"66","author":"Tsay","year":"2018","journal-title":"Clin. Infect. Dis."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Sabino, R., Ver\u00edssimo, C., Pereira, \u00c1.A., and Antunes, F. (2020). Candida auris, an agent of hospital-associated outbreaks: Which challenging issues do we need to have in mind?. Microorganisms, 8.","DOI":"10.3390\/microorganisms8020181"}],"container-title":["Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-0817\/14\/4\/328\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:04:13Z","timestamp":1760029453000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-0817\/14\/4\/328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,28]]},"references-count":63,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4]]}},"alternative-id":["pathogens14040328"],"URL":"https:\/\/doi.org\/10.3390\/pathogens14040328","relation":{},"ISSN":["2076-0817"],"issn-type":[{"value":"2076-0817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,28]]}}}