{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T19:10:54Z","timestamp":1760037054589,"version":"build-2065373602"},"reference-count":26,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T00:00:00Z","timestamp":1759795200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Human echinococcosis is a zoonotic disease caused by accidental ingestion of tapeworm eggs of the genus Echinococcus, shed in the feces of animal definitive host. In the human duodenum, these eggs release oncospheres, which penetrate the intestinal wall and via the bloodstream reach the liver\u2014the most common site for development of cysts. However, it is important to remember that any other organ can be affected via the bloodstream, due to larvae size. In Europe, the most diagnostically relevant species are Echinococcus granulosus, with a median incidence of 0.6 cases per 100,000 inhabitants, and Echinococcus multilocularis, with 0.1 cases per 100,000 inhabitants. This article aims to describe an exceptionally unusual location of human cystic echinococcosis in the anterior mediastinum. We describe the role of multidisciplinary diagnostics in establishing the definitive diagnosis. The pathomorphological examination, radiological imaging and serological testing for diagnosing cystic echinococcosis are hereby described. It is particularly important to avoid reporting unspecified Echinococcus (NOS) if possible, as the management and treatment of patients with echinococcosis varies depending on the species.<\/jats:p>","DOI":"10.3390\/pathogens14101016","type":"journal-article","created":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T15:48:30Z","timestamp":1759852110000},"page":"1016","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Unusual Case of Anterior Mediastinal Cystic Echinococcosis Successfully Resolved with Multidisciplinary Approach"],"prefix":"10.3390","volume":"14","author":[{"given":"Katarzyna","family":"Rodak","sequence":"first","affiliation":[{"name":"Department of Pathology, Regional Hospital SPWSZ in Szczecin, 71-455 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3648-0515","authenticated-orcid":false,"given":"Magdalena","family":"Mnichowska-Polanowska","sequence":"additional","affiliation":[{"name":"Department of Microbiology Immunology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Powsta\u0144c\u00f3w Wielkopolskich 72, 70-111 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3286-3779","authenticated-orcid":false,"given":"Arkadiusz","family":"Waloryszak","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery and Transplantation, Pomeranian Medical University in Szczecin, Alfreda Soko\u0142owskiego 11, 70-891 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5205-0489","authenticated-orcid":false,"given":"Konrad","family":"Ptaszy\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Pathology, Regional Hospital SPWSZ in Szczecin, 71-455 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5836-8498","authenticated-orcid":false,"given":"Janusz","family":"W\u00f3jcik","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery and Transplantation, Pomeranian Medical University in Szczecin, Alfreda Soko\u0142owskiego 11, 70-891 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0817-1018","authenticated-orcid":false,"given":"Ma\u0142gorzata Edyta","family":"Wojty\u015b","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery and Transplantation, Pomeranian Medical University in Szczecin, Alfreda Soko\u0142owskiego 11, 70-891 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1128\/CMR.17.1.107-135.2004","article-title":"Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern","volume":"17","author":"Eckert","year":"2004","journal-title":"Clin. 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